100% SeMet incorporationTrivial to solve

Impossible to solve

100% S -Met incorporation

Exchanging Se for S

00.10.20.30.40.50.60.70.80.9

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1

solvent flattened

fraction Sulfur

corr

elat

ion

co

effi

cien

t

ARP/wARP performance

00.10.20.30.40.50.60.70.80.9

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1

solvent flattened

ARP/wARP 7

fraction Sulfur

corr

elat

ion

co

effi

cien

t

29% Se 71% S

28% Se 72% S

ARP/wARP performance

00.10.20.30.40.50.60.70.80.9

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1

solvent flattened

ARP/wARP 7

phenix.autobuild

fraction Sulfur

corr

elat

ion

co

effi

cien

t

ARP/wARP performance

00.10.20.30.40.50.60.70.80.9

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1

solvent flattened

ARP/wARP 7

phenix.autobuild

crank2

fraction Sulfur

corr

elat

ion

co

effi

cien

t

ARP/wARP performance

00.10.20.30.40.50.60.70.80.9

1

0 0.1 0.2 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1

solvent flattened

ARP/wARP 7

phenix.autobuild

crank2

Tom Terwilliger

fraction Sulfur

corr

elat

ion

co

effi

cien

t

21% Se 79% S

11% Se 89% S