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    Dr. Mavrych, MD, PhD, DSc [email protected]

    100 must importantGA conceptions

     Dr. Mavrych, MD, PhD, DSc

     Dr. Bolgova, MD, PhD

    Understand first, then memorize and apply

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    Dr. Mavrych, MD, PhD, DSc [email protected]

    Dear students, youcanusethis presentationlikeaguideduring yourpreparing for GA exams.

    It does NOT cover all material of theGross Anatomy course. TocompleteGA material youshouldwork with ALL professor’s

    presentations.

    GoodLuck andAll thebest!Dr . Mavrych  

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    1. Lumbar puncture (tap) and

    Epidural anesthesia When lumbar puncture isperformed, the needleenters the subarachnoidspace to extractcerebrospinal fluid (CSF)or to inject anesthetic to

    epidural space. The needle is usually

    inserted between L3/L4 orL4/L5. Level of horizontalline through upper pointsof iliac crests.

    Remember, the spinal cord

    may ends as low as L2 inadults and does end at L3in children and dural sacextends caudally to level ofS2.

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    Patients typically have historyof back pain that may radiatedown to the lower limb.

    Herniation of disc usuallyoccurs in lumbar (L4/L5 or L5/S1) or cervical regions(C5/C6 or C6/C7) ofindividuals younger than age50.

    Herniated lumbar disc usuallycompreses the nerve root onenumber below: traversing root(e.g., the herniation L4/L5 willcompress L5 root).

    The pain begins soon afterpatient lifted some heavy thing.

    Lower limb reflexes aredecreased on the affected

    side

    2. Herniated IV disc

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    3. Abnormal curvatures of the

    spine Kyphosis is an exaggeration of

    the thoracic curvature that may

    occur in elderly persons as a result

    of osteoporosis (multiply

    compression fracture of vertebralbodies) or disk degeneration.

    Lordosis is an exaggeration of the

    lumbar curvature that may be

    temporary and occurs as a result

    of pregnancy, spondylolisthesisor potbelly.

    Scoliosis is a complex lateral

    deviation, or torsion, that is

    caused by poliomyelitis, a leg-

    length discrepancy, or hip disease.

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    4. Upper l imb fractures:

    Humerus fracturesSites of potential injury to major

    nerves in fractures of the humerus:

    1.  Axillary nerve and posterior

    humeral circumflex artery at thesurgical neck.

    2. Radial nerve and profunda brachii

    artery at midshaft. Midshaft

    fracture affect origin of brachialis

    muscle.

    3. Brachial artery and median nerve

    at the supracondylar region.

    4. Ulnar nerve at the medial

    epicondyle.

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    Fracture of distal radius: Transverse fracture within the distal 2 cm of

    the radius. Most common fracture of the

    forearm (after 50).

    Smith's fracture results from a fall or a blowon the dorsal aspect of the flexed wrist

    and produces a ventral angulation of the

    wrist. The distal fragment of the radius is

     ANTERIORLY displaced.

    Colles' fracture results from forced

    extension of the hand, usually as a result oftrying to ease a fall by outstretching the

    upper limb. Distal fragment is displaced

    DORSALLY - “dinner fork deformity”.

    Often the ulnar styloid process is avulced

    (broken off)

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    Scaphoid fracture Occurs as a result of a fall onto

    the palm when the hand isabducted

    Pain occurs primarily on thelateral side of the wrist,especially during wrist extensionand abduction

    Scaphoid fracture may not showon X-ray films for 2 to 3 weeks,but a deep tenderness will bepresent in the anatomicalsnuffbox.

    The proximal fragment mayundergo avascular necrosisbecause the blood supply isinterrupted.

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    Boxer’s fracture Necks of the metacarpal

    bones are frequently

    fractured during fistfights.

    Typically, fractures of 2d

    and3d metacarpals are seen in

    professional boxers, and

    fractures of 5th and sometimes

    4th metacarpals are seen in

    unskilled fighters.

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    Mallet or Baseball Finger  This deformity results from the DIP joint suddenly

    being forced into extreme flexion (hyperflexion)

    when, for example, a baseball is miscaught or a

    finger is jammed into the base pad.

    These actions avulse the attachment of theextensor digitorum tendon to the base of the

    distal phalanx. As a result, the person cannot

    extend the DIP joint. The resultant deformity bears

    some resemblance to a mallet.

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    5. Rotator cuff muscles – SITS Support the shoulder joint by

    forming a musculotendinous

    rotator cuff around it

    Reinforces joint on all sides

    except inferiorly, where

    dislocation is most likely

    Rotator cuff muscles are:

    Supraspinatus

    Infraspinatus

    Teres minor

    SubscapularisRight humerus

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    6. Abduction of the upper limb (0°-15°)  Abduction of the

    upper extremity is initiatedby the supraspinatusmuscle (suprascapular nerve).

    (15°-110º) Further abductionto the horizontal position is afunction of the deltoidmuscle (axillary nerve).

    (110°-180°) Raising theextremity above thehorizontal position requiresscapular rotation by actionof the trapezius (accessorynerve CNXI) and serratusanterior (long thoracic

    nerve).

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    Subacromial bursitis &

    Tearing of supraspinatus tendon Subacromial bursitis (inflammation of

    the subacromial bursa) is often due to

    calcific supraspinatus tendinitis,

    causing a painful arc of abduction.

    The same symptoms will be in case ofinflammation or trauma of the

    supraspinatus tendon (MRI→ torn

    tendon)

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    7. Three Elbows: Student's elbow

    (Subcutaneous olecranon bursitis) The olecranon, to which the triceps

    tendon attaches distally, is easilypalpated. It is separated from theskin by only the olecranon bursa,

    which allow the mobility of theoverlying skin.

    Repeated excessive pressure and

    friction may cause this bursa to

    become inflamed, producing a

    friction subcutaneous olecranon

    bursitis.

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    Tennis elbow

    (Lateral epicondylitis) Lateral epicondyli tis: repeated

    forceful flexion and extension of thewrist resulting strain attachment ofcommon extensor tendon and

    inflammation of periosteum oflateral epicondyle. Pain felt over lateral epicondyle and radiatesdown posterior aspect of forearm.Pain often felt when opening adoor or lifting a glass

    Origins of following muscles may

    be affected:1. Extensor Carpi Radialis

    Longus & Brevis

    2. Extensor Digitorum

    3. Extensor Digiti Minimi

    4. Extensor Carpi Ulnaris

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    Golfer’s elbow

    (Medial epicondylitis) Medial epicondyli tis is

    inflammation of the common

    flexor tendon of the wrist

    where it originates on the

    medial epicondyle of thehumerus.

    Origins of following musclesmay be affected:

    1. Pronator Teres

    2. Flexor Carpi Radialis3. Palmaris Longus

    4. Flexor Carpi Ulnaris

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    8. Arterial anastomoses

    around the scapula Blockage of the

    Subclavian or Axillaryartery can be bypassedby anastomoses

    between branches ofthe Thyrocervical andSubscapular arteries:

    Transverse cervical

    Suprascapular 

    Subscapular 

    Circumflex scapular 

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    9. Cubital fossa Contents from lateral to medial:

    1. Biceps brachii tendon

    2. Brachial artery

    3. Median nerve

    Subcutaneos structures from lateral tomedial:

    1. Cephalic vein

    2. Median cubi tal vein: joins cephalicand basilic veins

    3. Basilic vein

    Sites of venipuncture is usually mediancubital vein because: Overlies bicipital aponeurosis, so deep

    structures protected

    Not accompanied by nerves

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    10. Carpal Tunnel Syndrome Results from a lesion that

    reduces the size of the carpaltunnel (fluid retention, infection,dislocation of lunate bone)

    Median nerve – most sensitive

    structure in the carpal tunneland is the most affected

    Clinical manifestations: Pins and needles or anesthesia

    of the lateral 3.5 digits

    palm sensation is not affectedbecause superficial palmar

    cutaneous branch passessuperficially to carpal tunnel

     Apehand deformity - absentof OPPOSITION

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    11. Test of the proximal and

    distal interphalangeal joints

    PIP – FDS

    DID - FDP

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    12. Lesion of UL nerves

    Upper Brachial Palsy Injury of upper roots and trunk

    Usually results from excessiveincrease in the angle between theneck and the shoulder stretching or

    tearing of the superior parts of thebrachial plexus (C5 and C6 roots orsuperior trunk)

    May occur as birth injury fromforceful pulling on infant's headduring difficult delivery

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    Upper Brachial Palsy

    (Erb-Duchenne palsy) In all cases, paralysis of the muscles of the

    shoulder and arm supplied by C5 and C6 spinal

    nerves (roots) of the upper trunk.

    Combination lesions of axillary, suprascapular 

    and musculocutaneous nerves with loss of theshoulder mm and anterior arm.

     As result patient has “ waiter’s tip” hand:

    adducted shoulder 

    medially rotated arm

    extended elbow

    loss of sensation in the lateral aspect of the

    upper limb

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    Lower Brachial Palsy

    (Klumpke paralysis) Injury of lower roots and

    trunk

    May occur when the upper

    limb is suddenly pulled

    superiorly: stretching ortearing of the inferior parts

    of the brachial plexus (C8

    and T1 roots or inferior

    trunk)

    E.g., grabbing supportduring falling f rom height

    or as a birth injury, or 

    TOS – thoracic outlet

    syndrome

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    Lower Brachial Palsy

    (Klumpke paralysis)  All intrinsic muscles of the hand

    supplied by the C8 and T1 roots ofthe lower trunk affected.

    Combination lesions of ulnar nerve (“claw hand”) and mediannerve (“ape hand”)

    Loss of sensation in the medialaspect of the upper limb andmedial 1,5 fingers.

    May include a Horner syndrome

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    Injury to musculocutaneous

    nerve Usually results from lesions

    of lateral cord

    Greatly weakens f lexion ofelbow (biceps and brachialismuscles) and supination offorearm (biceps muscle)

    May be accompanied by

    anesthesia over lateralaspect of forearm

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    Cutaneous innervation

    of the hand

    Dorsum: 1,5-U and 3,5 R Palm: 1,5-U and 3,5 M

    In reality, in case of superficial branch of

    radial nerve lesion it will be skin deficitbetween 1 & 2 digi ts on the dorsum of the

    hand ONLY because of nerve overlapping

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    13. Cardiac catheterization

    The femoral artery isused for cardiaccatheterization

    It can be cannulatedfor left cardiacangiography & alsofor visualizing thecoronary arteries – along, slender catheteris insertedpercutaneously and

    passed up theexternal iliac artery,common iliac artery,aorta, to the leftventricle of the heart

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    14. Injury of the gluteal region

    Fractures of Femoral Neck

     A common fracture inelderly women withosteoporosis is fracture of the femoral neck.

    Fractures of the femoral

    neck cause shortness andlateral rotation of the lowerlimb.

    Fractures of the femoralneck often disrupt the bloodsupply to the head of thefemur.

     At present time the best wayin case of femoral neckfracture is hip replacement.

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     Avascular necrosis

    of femoral head

    Transcervical fracturedisrupts blood supply tothe head of the femur viaretinacular arteries (frommedial circumflex femoral

    artery) and may causeavascular necrosis of thefemoral head if bloodsupply through the ligamentto the head is inadequate.

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    Injury to sciatic nerve

    Weakened hipextension and kneeflexion

    Footdrop (lack ofdorsiflexion)

    Flail foot (lack ofboth dorsiflexion andplantar flexion)

    Cause of injury:

    caused byimproperly placedgluteal injectionsbut may result fromposterior hipdislocation

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    Posterior hip dislocations They are most common. A head-on

    collision that causes the knee to

    strike the dashboard may dislocate

    the hip when the femoral head is

    forced out of the acetabulum.

    The joint capsule ruptures inferiorly

    and posteriorly (fracture of ishium),

    allowing the femoral head to pass

    through the tear in the capsule

    (tearing of ishiofemoral lig.) and

    over the posterior margin of the

    acetabulum onto the lateral surface

    of the ilium, shortening and

    medial rotating the limb.

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    Superior gluteal

    nerve injury The superior gluteal nerve

    may be injured during surgery,posterior dislocation of thehip or poliomyelitis.

    Paralysis of the gluteus

    medius and gluteus minimusmuscles occurs so that theability to pull the pelvis upand abduction of the thighare lost.

    Trendelenburg sign:

    If the superior gluteal nerve on

    the right side is injured, the leftpelvis falls downward when thepatient raises the left foot off theground.

    Note that side is contralateral tothe nerve injury.

    Right

    superior

    gluteal nerve

    injury

    Normal

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    Injury to inferior gluteal nerve

    Weakened hip extension(gluteus maximus), mostnoticeable when climbing

    stairs or standing from aseated posit ion

    Cause of in jury: posteriorhip dislocation, surgery inthis region

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    Injury of obturator 

    nerve

    Difficulty adducting th igh

    (e.g., crossing legs while

    sitting)

    Decreased sensation

    over upper medial thigh

    Cause of injury: anterior

    hip dislocation, radical

    retropubic prostatectomia

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     Avulsion fractures occurwhere muscles areattached - ischialtuberosities

    Hamstrings muscles:

    1. Biceps femoris

    2. Semitendinosus

    3. Semimembranosus

     Action: extension of hip

     joint and flexion of knee joint

    Nerve supply – Tibialnerve (short head ofbiceps femoris is suppliedby the common fibular nerve)

    15. Avulsion fractures

    of the hip bone and

    hamstrings muscles

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    16. Structures under inguinal

    ligament:

    From lateral tomedial side:

    Iliopsoas muscle

    Femoral nerve Femoral artery

    Femoral vein

    Femoral canal

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    Femoral hernia

     A femoral hernia passes below

    inguinal ligament through the femoral

    ring into the femoral canal to form a

    swelling in the upper thigh inferior andlateral to the pubic tubercle

    The hernial sac may protrude through

    the saphenous hiatus into the

    superficial fascia

     A femoral hernia occurs more

    frequently in females and is dangerousbecause the hernial sac may become

    strangulated

     An aberrant obturator artery is

    vulnerable during surgical repair 

    Inguinal lig .

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    17. Knee joint injuries:

    Unhappy triad

    Because the lateral side of theknee is struck more often(e.g., in a football tackle), thetibial collateral ligament is

    the most frequently tornligament at the knee.

    The unhappy triad of athleticknee injuries involves:

    1. Tibial collateral l igament

    2. Medial meniscus

    3.  Anterior cruciate ligament

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    Tibial collateral ligament

    (medial collateral ligament)

    Broad flat band

    extending from medial

    epicondyle of femur to

    medial condyle andshaft of tibia

    Blends with capsule and

    firmly attaches to

    medial meniscus

    Limits extension and

    abduction of leg at

    knee

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    Fibular collateral l igament

    (lateral collateral ligament)

    Rounded cord between

    lateral epicondyle of femur

    and head of fibula

    Does NOT blend with jointcapsule and does NOT

    attach to lateral meniscus

    Limits extension and

    adduction of leg at knee

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    Rupture of the

    cruciate ligaments

    With rupture of the anteriorcruciate ligament, the tibiacan be pulled forwardexcessively on the femur,

    exhibiting anterior drawersign.

    In the less common rupture ofthe posterior cruciateligament, the tibia can bepushed backward excessively

    on the femur, exhibitingposterior drawer sign.

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    Prepatellar bursa

    Suprapatellar bursa

    Prepatellar bursa: between

    superficial surface of patella

    and skin. May become

    inflamed and swollen

    (prepatellar bursitis).

    Suprapatellar bursa: superior

    extension of synovial cavity

    between distal end of femur

    and quadriceps muscle and

    tendon. Usual place for intra-

    articular injections. May

    become inflamed and swollen

    (suprapatellar bursitis).

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    Knee jerk reflex

    The patellar reflexis tested by tappingthe patellarligament with a

    reflex hammer toelicit extension atthe knee joint. Bothafferent andefferent limbs ofthe reflex arch arein the femoral

    nerve (L2-L4).

    Knee jerk reflex:tests spinal nervesL2-L4.

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    18. Ankle joint injuries:

     Ankle sprains

    Sprains are the most commonankle injuries

     A sprained ankle is nearlyalways an inversion injury,

    involving twisting of the weight-bearing plantarflexed foot.

    The lateral ligament (anteriortalofibular ligament) is injuredbecause it is much weaker thanthe medial ligament.

    In severe sprains, the lateralmalleolus of the fibula may befractured.

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    Pott’s fracture

    It is fracture-dislocations of

    the ankle joint Reason - forced eversion

    (abduction) of the foot

    The Deltoid ligamentavulses the medialmalleolus and after thatfibula fractures at ahigher level

    Pott's fracture

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     Ankle jerk reflex

     Achilles tendon reflex is

    tested by tapping the

    calcaneal tendon to elicit

    plantar flexion at the ankle joint.

    Both afferent and efferent

    limbs of the reflex arc are

    carried in the tibial nerve

    (S1, S2).

     Ankle jerk reflex: tests

    spinal nerves S1-S2.

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    19. Injures of the leg and foot:

    Fracture of the fibular neck May cause an injury to the common

    peroneal nerve, which windslaterally around the neck of thefibula.

    This injury results in paralysis of allmuscles in the anterior and lateralcompartments of the leg(dorsiflexors and evertors of thefoot) and loosing sensation on thedorsum of the foot.

    Causing foot drop.

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    Rupture of the Achilles tendon

    and Triceps surae muscle

     Avulsion or rupture of the calcaneal

    ( Achilles) tendon disables the triceps

    sure muscle (gastrocnemius & soleus)

    so that the patient cannot plantar flexthe foot.

    Triceps surae muscle:

    2 Heads of Gastrocnemius m.

    1 Head - Soleus muscle

    Plantaris

    small fusiform belly with long thintendon;

    sometimes may becomehypertrophy

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    Plantar Fasciitis (calcaneal spur)

    Plantar fasciitis is the

    most common hindfoot

    problem in runners. It

    causes pain on the

    plantar surface of thefoot and heel.

    Point tenderness is

    located at the proximal

    attachment of the plantar

    aponeurosis to themedial tubercle of the

    calcaneus and on the

    medial surface of this

    bone.

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    20. Injury of tibial nerve

    In popliteal fossa: loss ofplantar flexion of foot (mainlygastrocnernius and soleusmuscles) and weakened

    inversion (tibialis posteriormuscle), causingcalcaneovalgus.

    Inabili ty to stand on toes

    Loss of sensation andparalysis of intrinsic musclesof the sole of the foot Popliteal fossa from superficial to

    deep, contains:

    Tibial nerve

    Popliteal vein

    Popliteal artery

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    On soil of the foot there are two terminal

    branches of tibial n:

    Medial plantar nerve supplies:

    1.  Abductor hallucis,2. Flexor hallucis brevis

    3. Flexor digitorum brevis

    4. 1st lumbrical muscles

    skin of medial 3.5 digits

    Lateral plantar nerve supplies:  All intrinsic plantar muscles which

    are not innervated by medial plantar

    nerve

    skin of lateral 1.5 digits

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    21. Breast:

    Carcinoma of the Breast

    Carcinomas of thebreast are malignanttumors, usuallyadenocarcinomasarising from theepithelial cells of thelactiferous ducts in themammary glandlobules

    1. It enlarges, attachesto suspensory(Cooper‘s) ligaments,and producesshortening of theligaments, causingdepression or dimplingof the overlying skin.

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    Lymphatic drainage

    of the breast

    It is important becauseof its role in themetastasis of cancercells.

    Most lymph (> 75%),especially from thelateral breastquadrants , drains tothe axillary lymphnodes, initially to theanterior (pectoral)nodes for the most

    part. Most of the remaining

    lymph, particularly fromthe medial breastquadrants, drains to theparasternal lymphnodes or to theopposite breast.

    75% 25%

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    Mastectomy

    Radical mastectomy, a more extensive surgicalprocedure, involves removal of the breast, pectoralmuscles, fat, fascia, and as many lymph nodes aspossible in the axilla and pectoral region.

    1. During a radical mastectomy, the long thoracicnerve may be lesioned during ligation of the lateral

    thoracic artery. A few weeks after surgery, the

    female may present with a winged scapula and

    weakness in abduction of the arm above 90°

    because serratus anterior m. paralysis.

    2. The intercostobrachial nerve may also be

    damaged during mastectomy, resulting in skin

    deficit of the medial arm.

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    Breast infection

    Mastitis is an infection of the tissue

    of the breast that occurs most

    frequently during the time of

    breastfeeding (1 to 3months after the

    delivery of a baby).

    This infection causes pain, swelling,

    redness, and increased temperature

    of the breast.

    It can occur when bacteria, often from

    the baby's mouth, enter a milk ductthrough a crack in the nipple.

    It can occur in women who have not

    recently delivered as well as in women

    after menopause.

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    22. Thoracic wall & Diaphragm:

    Intercostal spaces

    Intercostal blood vesselsand nerves:

    run between theinternal intercostal andinnermost intercostal

    muscles in the costalgroove

    arranged from superiorto inferior as vein,artery, nerve

    Most vulnerablestructures – intercostalnerve and posteriorintercostal arterybecause they are notcovering by ribs.

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    Diaphragm:

    Paralysis of half and ruptures

    Paralysis of the halfof the Diaphragmmay result from injuryor operative division of

    the phrenic nerve ofsame side

    It can be detectedradiologically .

    Paradoxicalmovement: dome ofdiaphragm of injuredside pushed superiorlyby abdominal visceraduring inspirationinstead of descending

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    Phrenic nerve

     Arises from the anteriorbranches C3-C5 nerves andlies in front of the anteriorscalene muscle.

    Runs anterior to the root ofthe lung, whereas the vagusnerve runs posterior to theroot of the lung.

    Innervates the fibrouspericardium, themediastinal anddiaphragmatic pleurae(sensory innervation), andthe diaphragm for motor and its central tendon forsensory.

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    Diaphragmatic ruptures

    Diaphragmatic injuries are

    relatively rare and result from

    either blunt trauma or 

    penetrating trauma.

    Presently, 80-90% of blunt

    diaphragmatic ruptures resultfrom motor vehicle crashes.

    The majority (80-90%) of blunt

    diaphragmatic ruptures have

    occurred on the left side.

    Blunt trauma typically produceslarge radial tears measuring 5-15

    cm, most often at the

    posterolateral aspect of the

    diaphragm.

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    23. Cardiac hypertrophy Left atrial enlargement

    (hypertrophy) secondary to

    mitral valve failure may

    compress on theesophagus and manifest

    as dysphagia (difficulty in

    swallowing).

    It may be observed as a

    filling defect in the

    esophagus by barium

    swallow on the lateral

    thoracic X-Ray

    P A j ti

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    Cardiac Shadow

    Right border is formed by:

    1. SVC,2. Right atrium

    Left border is formed by:

    1.  Aortic arch2. Pulmonary trunk

    3. Left auricle

    4. Left ventricle

    P-A projection

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    24. Auscultation of Heart

    Valves

    Right 2 ICS

    PSL

    Left 5 ICS

    MCL

    Left 4 ICS

    PSL

    Left 2 ICS

    PSL

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     Auscultation sites for

    mitral and aortic murmurs

     A heart murmur is heard downstream from the valve: stenosis is orthograde direction from valve

    insufficiency is retrograde direction from valve

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    25. Conducting System

    of the Heart Sinoatrial (SA) node site where contraction of heart muscle is

    initiated (pacemaker of the heart)

    situated in the upper part of the sulcusterminalis just near to the opening ofthe SVC

     Atrioventr icular (AV) node the AV node receives impulses from the

    SA node; situated in the lower part ofthe atrial septum near coronary sinus

     Atrioventr icular bundle of His

    descends from the AV node to themembranous portion of the ventricularseptum where it divides into the left andright bundle branches

    Right bundle branch – passes down toreach the moderator band - rightventricle

    left bundle branch – passes down leftside of ventricular septum

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    26. Blood supply of the Heart:

    Right coronary artery (RCA) It supplies major parts of the right

    atrium and the right ventricle.

    It anastomoses with the marginalbranch of the left coronary arteryposteriorly

    Branches:

    1.  Anterior cardiac branches – supplies the right atrium

    2. Nodal branch – supplies the (1) SAnode, (2) AV node

    3. Marginal artery – supplies the rightventricle

    4. Posterior interventricular artery – supplies (1) diafragmatic (inferior)surface of both ventricles and (2)posterior 1/3 of the IV septum

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    Left coronary artery

    (LCA)Branches:

    1.  Anterior (descending)

    interventricular artery – most

    common place of MI descends in the

    anterior interventricular sulcus and

    provides branches to the (1) anterior

    heard wall, (2) anterior 2/3 of IV

    septum, (3) bundle of His, and (4)

    apex of the heart.

    2. Circumflex artery – winds around the

    left margin of the heart in theatrioventricular groove to anastomose

    with the right coronary artery

    posteriorly; supplies the left atrium

    and left ventricle

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    Blood supply of the conducting

    system SA node – RCA

     AV node – RCA

     AV bundle (andmoderator band)- LCA

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    27. Congenital cardiac defects:

     Atrial Septal Defect (ASD) It is less frequent than

    VSD

    It results from failure toclose of the foramenovale after birth (failure ofthe septum primum andseptum secundum tofuse)

    Postnatally, ASDs resultin left-to-right shunting(between right and left

    atrium) and are non-cyanotic conditions.

    If it is small, has noclinical significance & iflarge - necessary surgicalrepair 

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    Ventricular Septal

    Defect (VSD) Ventricular septal defect

    (VSD) is the most commonof the congenital heart defects

    It may be found in the

    membranous part of theventricular septum andresults from failure to fuse ofthe membranous portion withthe muscular portion of theventricular septum

    In this case, present left–to-

    right shunt (right ventricularhypertrophy (RVH)) andagain non-cyanotic.

    Necessary surgery for largedefects

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    Patent Ductus Arteriosus (PDA) It results from failure of the ductus

    arteriosus (a connection between thepulmonary trunk and aorta) to constrict andclose after birth.

    Prostaglandin E and low O2 tension sustainpatency of the ductus arteriosus in the fetalperiod.

    PDA is common in premature infants and incases of maternal rubella infection.

    Left –to-right shunt increased pressure inpulmonary circulation (pulmonary

    hypertension) and is non-cyanotic Treatment: surgical division and ligation

    imperative. In great danger is left recurrentnerve (wrapping aorta arch). Injure of thisnerve results in hoarseness.

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     Aneurysm of the aorta

     Aneurysm of the aortic arch:compresses the left recurrentlaryngeal nerve, leading tocoughing, hoarseness, andparalys is of the ipsilateral vocal

    cord. It may cause dysphagia(difficulty in swallowing), resultingfrom pressure on the esophagus,and dyspnea (difficulty inbreathing), resulting frompressure on the trachea, root ofthe lung, or phrenic nerve

     Aneurysm of the thoracic aortamay compress and tug on thetrachea with each cardiac systoleso that the aneurysm can be feltby palpating the trachea at thesternal notch (T2).

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     Abdominal aortic aneurysm

    It is a localized dilatation of the

    aorta. It is typically happened

     just above of the bifurcation at

    level of L4 and crossed by 3rd

    part of duodenum.

    Pulsations of a large aneurysm

    can be detected to the left of

    the midline at the umbilical

    region.

     Acute rupture of an abdominal

    aortic aneurysm is associated

    with severe pain in theabdomen or back (mortality rate

    is nearly 90%).

    Surgeons can repair an

    aneurysm by opening it and

    inserting a prosthetic graft.

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    Coarctation of the Aorta It results from congenital

    narrowing of the aorta distal to theoffshoot of the left subclavianartery.

    Cardinal clinical sign: higher blood

    pressure in the upper limbscompared to the lower limbs.

    Coarctation of the aorta results inthe intercostal arteries providingcollateral circulation between theinternal thoracic artery and thethoracic aorta to provide blood

    supply to the lower parts of thebody

    Coarctation of the Aortacharacteristic X-ray picture:serrated appearance of inferiorborders of ribs (rib notching)

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    28. Aspiration of Foreign

    Bodies & Bronchopulmonary

    segments Aspiration of Foreign Bodies:

    Inhalation of FB’s (e.g. pins,parts of teeth, screws, nuts,bolts, toys) into the lowerrespiratory tract is common,especially in children

    More likely to enter the rightprimary bronchus and pass intothe middle or lower lobebronchi

    If the vertical position of thebody, the foreign body usuallyfalls into the posterior basalsegment of the right inferiorlobe.

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    Right lung:

    10 bronchopulmonary segments

    Superior lobe:

    1.  Apical2.  Anterior 

    3. Posterior Middle lobe:

    4. Lateral5. MedialInferior lobe:

    6. Superior 7.  Anterior basal8. Posterior basal9. Lateral basal10.Medial basal

    1

    8

    97

    6 4

    5

    2

    3

    10

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    Left lung:

    9 bronchopulmonary segments

    Superior lobe:

    1.  Apicoposterior 2.  Anterior 3. Superior lingular 4. Inferior lingular Inferior lobe:

    5. Superior 6.  Anterior basal

    7. Posterior basal8. Lateral basal9. Medial basal

    1

    3 5

    7

    89

    6

    2

    4

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    29. Lung diseases:

    Pneumonia Pneumonia is an inflammation

    of the lung, caused by an

    infection or chemical injury to the

    lungs.

    Three common causes are

    bacteria, viruses and fungi.

    Symptoms: cough, chest pain,

    fever, and difficulty in breathing.

    Chest x-rays: areas of opacity

    (seen as white) of the lungparenchyma and enlargement of

    bronchomediastinal lymph

    nodes (mediastinal widening).

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    Bronchogenic Carcinoma

     Arises in the mucosa of thelarge bronchi

    Produces as persistent,

    productive cough orhemoptysis

    Early metastasis to thoracic(bronchomediatinal) lymphnodes

    Hematogenous spread to thebrain, bones, lungs,

    suprarenal glands  A tumor at the apex of the

    lung (Pancoast tumor ) mayresult in thoracic outletsyndrome

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    Bronchogenic carcinoma

    may lead to:1. Thoracic outlet syndrome (TOS)

    It can cause pressure on the lowertrunk of the brachial plexus C8-T1and subclavian artery by cervical

    rib or pancoast tumor. It results inpain down the medial side of theforearm and hand and atrophy ofthe intrinsic hand muscles)

    2. Horner syndrome:

    miosis - constriction of the pupildue to paralysis of the dilator

    pupillae muscle ptosis - drooping of the eyelid due

    to paralysis of the superior tarsalmuscle

    hemianhydrosis - loss of sweatingon one side

    11

    22

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    Bronchogenic carcinoma

    may lead to:3. Superior vena cava

    syndrome, which causesdilation of the head andneck veins, facial swelling,and cyanosis

    4. Dysphagia as a result ofesophageal obstruction

    5. Hoarseness as a result ofrecurrent laryngeal nerveinvolvement

    6. Paralysis of the

    diaphragm as a result ofphrenic nerve involvement33

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    Qs about Auscultation

    and penetrated wounds To listen to breath sounds of the

    superior lobes of the right and left

    lungs, the stethoscope is placed on

    the superior area of the anterior

    chest wall (above the 4th rib for the

    right lung & above 6th for the left

    one).

    For breath sounds from the

    middle lobe of the right lung, the

    stethoscope is placed on the

    anterior chest wall between the 4th

    and 6th ribs

    For the inferior lobes of both

    lungs, breath sounds are primarily

    heard on the posterior chest wall.

    4

    6

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    30. Open pneumothorax &

    pleura It is entry of air into a pleural

    cavity causing lung collapse.

    Open pneumothorax – due to stabwounds of the thoracic wall whichpierce the parietal pleura so thatthe pleural cavity is open to theoutside air via the lung or throughthe chest wall.

     Air moves freely through thewound during inspiration andexpiration. During inspiration, airenters the chest wall and the

    mediastinum will shift toward otherside and compress the oppositelung. During expiration , air exitsthe wound and the mediastinummoves back toward the affectedside.

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    Pleura & Pleural Cavity 1. Cervical p leura may be affected in

    case of improper subclavianvenipuncture.

    2. Costodiaphragmatic Recess isdeepest place in pleural cavity, aroundthe chest wall, there are two ribinterspaces separating the inferiorlimit of parietal pleural reflections fromthe inferior border of the lungs andvisceral pleura:

    1. Midclavicular line - between ribs 6-82. Midaxillary line - between ribs 8-10

    3. Paravertebral line between ribs 10-12

    2

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    Nerve supply of the pleuraParietal Pleura – sensitive to general

    sensibilities (pain, temperature, touch,and pressure) - somatic sensoryinnervation:

    costal pleura – intercostal nervesblock may be used to decreasethoracic pain

    mediastinal pleura – phrenic nerve

    diaphragmatic pleura – phrenic nerveover the domes and lower 6 intercostalnerves around the periphery

    Visceral Pleura – sensitive to stretch butinsensitive to general sensibilities;autonomic nerve supply from thepulmonary plexus

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    31. Mediastinum

    Superior mediastinum Improperly done

    sternal puncturemay affectstructures related

    to the posteriorsurface of themanubriumsternum:

    In upper part – Leftbrachiocephalic

    vein In lower part – 

     Aort ic arch

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    Thoracic duct

    Function – conveys to theblood all lymph from thelower limbs, pelvic cavity,abdominal cavity, left side

    of the thorax, left side ofthe head & neck, and leftupper limb (3/4 of thebody)

    Tributaries – at the root of theneck

    Left jugular lymph trunk Left subclavian lymph

    trunk

    Left bronchomediastinallymph trunk

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    Constrictions of the esophagusThere are sites where ingested

    foreign bodies can lodge orwhere strictures may developfollowing ingestion of causticfluids, common sites of

    esophageal carcinoma

    1. C6 - where the pharynx joinsthe upper end (6" from theupper incisors)

    2. T4-T5 - where the aortic archand left main bronchus cross

    its anterior surface (10" from theupper incisors)

    3. T10 - where it passes throughthe diaphragm into thestomach (16" from the upperincisors)

    1

    2

    3

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    32. Anterior abdominal wall

    The liver and gallbladder are in the right upperquadrant;

    The stomach and spleen

    are in the left upperquadrant;

    The cecum and appendixare in the right lowerquadrant;

    The end of the descendingcolon and sigmoid colonare in the left lowerquadrant.

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    Referred abdominal pain

    Pain arising out of theforegut derived structuresis referred to the

    epigastric region.

    Pain arising out of themidgut derived structuresis referred to theumbilical region.

    Pain arising out of thehindgut derivedstructures is referred tothe hypogastric region.

    Nerve supply of the

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    Nerve supply of the

    anterior abdominal wall

    Therefore totally 7 nerves:lower 5 intercostals, 1subcostal and L1(iliphypogastric andilioinguinal) nerves supply

    the anterior abdominal wall. L1 can be anaesthetized by

    injecting 1 inch (2.5 cm)superior to the anteriorsuperior iliac spine.

     All nerves and deep blood

    vessels lie in theneurovascular plane:between internal obliqueand transversus muscles

    Arterial supply of the anterior

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     Arterial supply of the anterior

    abdominal wall:

    Important SUPERFICIAL

     ARTERIES (supply skin) are:

    1. Superficial epigastric

    2. Superficial circumflex iliac

    Important DEEP ARTERIES lie inthe neurovascular plane:

    1. Superior epigastric

    2. Posterior intercostals arteries

    3. Lumbar arteries

    4. Deep circumflex iliac artery

    5. Inferior epigastric

    33 Herniations

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    33. Herniations

    Hernia consist of 3 parts:

    Hernial sac is a pouch(diverticulum) of peritoneum andhas a neck and a body

    Hernial contents may consist ofany structure found in the

    abdominal cavity (more offen – loops of small intestine andpiece of omentum major)

    Hernial coverings are formedfrom the layers of the abdominalwall through which the hernial

    sac passes

    T li f i i th FIRST

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    Transversalis fascia is the FIRST

    STRUCTURE which is crossed by

    any abdominal hernia

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    Indirect Inguinal Hernia

    Indirect inguinal hernia is the mostcommon form of hernia and is believedto be congenital in origin (boys 0-3years).

    It passes through the deep inguinal ring

    lateral to the inferior epigastricvessels, inguinal canal, superficialinguinal ring and descend into thescrotum.

     An indirect inguinal hernia is about 20times more common in males than infemales, and nearly 1/3 are bilateral.

    It is more common on the right(normally, the right processus vaginalisbecomes obliterated after the left; theright testis descends later than the left).

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    Direct Inguinal Hernia

    Direct inguinal hernia composesabout 15% of all inguinal hernias.

    During a direct inguinal hernia,the abdominal contents willprotrude through the weak area of

    the posterior wall of the inguinalcanal medial to the inferiorepigastric vessels in the inguinal[Hesselbach's] triangle and afterthat through superficial inguinalring. It never descends into thescrotum.

    It is a disease of old men withweak abdominal muscles. Directinguinal hernias are rare in women,and most are bilateral.

    34 P it l t t

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    34. Peritoneal structures:

    Lesser omentum

    Consist of 2 ligaments:

    hepatogastric

    hepatoduodenal

    Contents : Right & Left gastric

    vessels

    Connective and fattytissue

    and Portal triad:

    Bile duct

    Portal vein

    Proper hepatic artery

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    Epiploic (winslow’s) foramen

     Anteriorly: The freeborder of thehepatoduodenalligament, containingportal triad (DV A).

    Posteriorly: IVC

    Superiorly: Caudate

    lobe of the liver .

    Inferiorly: The 1st

    part of theduodenum.

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    Douglas (rectouterine) pouch

    Rectouterine pouch(pouch of Douglas):deeper point of

    peritoneal space invertical position of thefemale body between therectum and the cervix ofuterus.

    It is space of the pelvic

    abscess location.

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    Culdocentesis

    Culdocentesis isaspiration of fluid fromthe cul-de-sac ofDouglas (rectouterinepouch) by a needle

    puncture of theposterior vaginalfornix near the midlinebetween the uterosacralligaments

    Because therectouterine pouch is

    the lowest portion ofthe female peritonealcavity, it can collectinflammatory fluid(pelvic abscess).

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    35. Smart Table

    FOREGUT MIDGUT HINDGUT

    Esophagus

    Stomach

    Duodenum (1st and

    2nd parts)

    Liver 

    Pancreas

    Biliary apparatus

    Gallbladder 

    Duodenum (2nd, 3rd,

    4th

    parts)

    Jejunum

    Ileum

    Cecum (with

     Appendix)

     Ascending colon

    Transverse colon(proximal 2/3)

    Transverse colon

    (distal 1/3)

    Descending colon

    Sigmoid colon

    Rectum (anal canal

    above pectinate line)

    FOREGUT MIDGUT HINDGUT

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    FOREGUT MIDGUT HINDGUT

     Artery: CA  Artery: SMA  Artery: IMA

    Parasympathetic

    innervation: vagus

    nerves, CNX

    Parasympathetic

    innervation: vagus

    nerves, CNX

    Parasympathetic

    innervation: pelvic

    splanchnic nerves, S2-S4

    Sympathetic

    innervation:

    •Preganglionics: greater splanchnic nerves, T5-T9

    •Postganglionics:

    celiac ganglion

    Sympathetic

    innervation:

    •Preganglionics: lesser splanchnic nerves, T10-

    T11

    •Postganglionics:

    superior mesenteric

    ganglion

    Sympathetic

    innervation:

    •Preganglionics: lumbar splanchnic nerves, L1-L2

    •Postganglionics: inferior 

    mesenteric ganglion

    Sensory Innervation:DRG T5-T9

    Sensory Innervation:DRG T10-T11

    Sensory Innervation:DRG L1-L2

    Referred Pain:

    Epigastrium

    Referred Pain:

    Umbilical

    Referred Pain:

    Hypogastrium

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    36. Posterior gastric ulcer 

    1. Posterior gastric ulcer mayerode through the posteriorwall of the stomach into the

    Omental bursa (Lesserperitoneal sac) and affectpancreas resulting inreferred pain to the back.

    2. Erosion of splenic artery is

    very common in posteriorgastric ulcers as wellbecause of the proximity ofthe artery to this wall.

    37 Congenital diaphragmatic

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    37. Congenital diaphragmatic

    hernia

    Hernia of stomach orintestine through aposterolateral defect

    in diaphragm(foramen ofBochadalek).

    It is seen in infantsand the mortality rate ishigh because of left

    lung hypoplasia.

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    38. Sliding hiatal hernia

     A sliding hiatal hernia which

    occurs in individuals past

    middle age is caused by

    the hernia of cardia of thestomach into the thorax

    through the esophageal

    hiatus of the diaphragm.

    This can damage the vagal

    trunks as they pass throughthe hiatus and resulting in

    hyposecretion of gastric

     juice.

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    39. Meckel's diverticulum

    Meckel's diverticulum is a congenitalanomaly representing a persistent portion ofthe vitellointestinal duct.

    This condition is often asymptomatic butoccasionally becomes inflamed if it containsectopic gastric, pancreatic, or endometrial

    tissue, which may produce ulceration. Meckel's diverticulum is located on the

    Ileum about 2 feet (61 cm) before theileocecal junction and SMA supply it. Itoccurs in 2% of patients and is about 2 inches(5 cm) long.

    The diverticulum is clinically importantbecause diverticulitis, liberation, bleeding,perforation, and obstruction are complicationsrequiring surgical intervention and frequentlymimicking the symptoms of acuteappendicitis.

    40 Features of the large

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    40. Features of the large

    intestine

    Features of the large intestine:

    1.  Appendices epiploic

    2. Sacculations(haustrations)

    3. Taeniae coli

    The taeniae coli meettogether at the base ofthe appendix where theyform a complete

    longitudinal muscle coatfor the appendix.

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    Colon

    The ascending colon liesretroperitoneally and lacks amesentery.

    It is continuous with thetransverse colon at the right(hepatic) flexure (1) of colon.

    The transverse colon (3) hasits own mesentery called thetransverse mesocolon(intraperitoneal position).

    It becomes continuous with thedescending colon at the left

    (splenic) flexure (2) of colon. The sigmoid colon (4) is

    suspended by the sigmoidmesocolon (intraperitonealposition).

    1

    3

    4

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    41. Pain of Appendicitis

    In appendicitis, first pain isreferred around the umbilicus.Visceral pain in the appendix isproduced by distention of itslumen or spasm of its muscle.

    The afferent pain fibers enterthe spinal cord at the level ofT10 segment, and a vaguereferred pain is felt in the regionof the umbilicus.

    Later if parietal peritoneum

    gets involved, and then the painis shifted laterally to the McBurney’s point. Here the painis precise, severe, and localized(second pain)

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    Mc Burney's point

    This point indicatesthe surface markingof the base of theappendix.

    It is a point at the

     junction between thelateral 1/3 andmedial 2/3 of a line

     joining the rightanterior superior iliacspine with theumbilicus.

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    42. Volvulus

    Because of its extreme mobility,

    the Jejunum, Ileum and

    Sigmoid colon sometimes

    rotates around its mesentery.It results in avascular necrosis

    corresponding part of interstine.

    This may correct itself

    spontaneously, or the rotation

    may continue until the blood

    supply of the gut is cut off

    completely.

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    43. Hirschsprung's Disease

    It is a rare congenital abnormality thatresults in obstruction because theintestines do not work normally.

    It is commonly found in Down Syndromechildren.

    The inadequate motility is a result of anaganglionic section (congenital absentsof postganglionic parasympatheticneurons inside of the intestinal wall) of theintestines resulting in megacolon.

    In a newborn, the main signs andsymptoms are failure to pass a

    meconium stool within 1-2 days afterbirth, reluctance to eat, bile-stained(green) vomiting, and abdominaldistension.

    Treatment is removal of the aganglionicportion of the colon.

    44 Branches of Abdominal aorta

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    44. Branches of Abdominal aorta

    and Mesenteric ischemia

    Celiac trunk (CA) originatesfrom the aorta at the lowerborder of T12 vertebra

    Superior mesenteric arteryoriginates at the lower

    border of L1 vertebra Renal arteries originate at

    approximately L2 vertebra

    Inferior mesenteric arteryoriginates at L3 vertebra

    Two terminal branches are

    common iliac arteries atthe level of L4 vertebra

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    CELIAC ARTERY (TRUNK)

    Origin: T12, just below the

    aortic opening of the

    diaphragm.

    The CA passes above the

    superior border of thepancreas and then divides

    into three retroperitoneal

    branches:

    Left gastric artery (1)

    Common hepatic artery (2) Splenic artery (3)

    2

    3

    1

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    Left gastric artery

    The left gastric artery (1)

    courses upward to the left to

    reach the lesser curvature of

    the stomach and may be

    subject to erosion by a

    penetrating ulcer of thelesser curvature of the

    stomach.

    Branches:

    Esophageal branches (2) - tothe abdominal part of theesophagus

    Gastr ic branches (3) supply

    the left side of the lesser

    curvature of the stomach and

    make anastomosis with right

    gastric artery.

    2

    3

    1

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    Common hepatic artery

    The common hepatic artery

    (1) passes to the right to

    reach the superior surface of

    the first part of the duodenum,

    where it divides into its two

    terminal branches:

    Proper hepatic artery (2)

    Gastroduodenal artery (3)

    1

    2

    3

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    Proper hepatic artery Proper hepatic artery (1) gives

    off right gastric artery (2) and

    then ascends within the

    hepatoduodenal ligament of the

    lesser omentum to reach the

    porta hepatis, where it divides

    into the right (4) and left (3)hepatic arteries.

    The right and left arteries enter the

    two lobes of the liver , right

    hepatic artery gives cystic artery

    (5) to the gallbladder .

    Right gastric artery (2) suppliesthe right side of the lesser

    curvature of the stomach where it

    anastomoses the left gastric

    artery.

    54

    3

    21

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    Gastroduodenal artery

    Gastroduodenal artery (1)

    descends posterior to the first

    part of the duodenum (may be

    subject to erosion by a

    penetrating ulcer in this place)

    and divides into two branches:

    Right gastroepiploic artery (2)

    (supplies the right side of the

    greater curvature of the

    stomach where it anastomoses

    the left gastroepiploic)

    Superior pancreaticoduodenal

    arteries (3) (supply the head of

    the pancreas, where they

    anastomoses the inferior

    pancreaticoduodenal arteries

    from the SMA).

    1

    2

    3

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    Ligature of the hepatic artery:

    The hepatic artery may beligated proximal to the originof its gastroduodenal branch,a collateral circulation to theliver is established throughthe left and right gastric

    arteries, left and rightgastroepiploic andgastroduodenal arteries.

    The right hepatic arterymay be mistakenly ligatedduring holecystectomy in

    Calot triangle together withthe cystic artery, right lobehepatic necrosis commonlyoccurs.

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    Splenic artery

    Splenic artery (1) runs a

    tortuous horizontal course to

    the left along the upper border

    of the pancreas, behind the

    peritoneum of the posterior

    wall of the lesser sac, forming apart of the stomach bed.

    The splenic artery may be

    subject to erosion by a

    penetrating ulcer of the

    posterior wall of the stomach

    into the lesser sac.

    N.B. The splenic vein runs amore straight course below theartery and behind of thepancreas.

    1

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    Splenic artery

    Splenic (1) a. is retroperitoneal

    until it reaches the tail of the

    pancreas, where it enters the

    splenorenal ligament to enter

    the hilum of the spleen.

    Branches: Branches to the spleen (2)

    Branches to the neck, body, and

    tai l of pancreas (3)

    Left gastroepiploic (4) artery that

    supplies the left side of the

    greater curvature of the stomachwhere it anastomoses the right

    gastroepiploic

    Short gastric (5) branches that

    supply fundus of the stomach

    5

    43

    1 2

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    SMA Branches:

    (1) Inferiorpancreaticoduodenalarteries

    (2)Jejunal and (3)Ileal branches

    (4) Ileocolic artery

     Ascending branch

     Anterior cecal artery

    Posterior cecal artery

    (5) Appendicularartery

    (6) Right colic artery

    (7) Middle colic artery

    17

    6

    5

    4

    3

    2

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    IMA Branches:

    (1) Left colic artery

    (2) Sigmoid arteries

    (3) Superior rectal artery

    3

    2

    1

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    Mesenteric ischemia  Atherosclerosis, which slows the

    amount blood flowing through arteries, isa frequent cause of chronic mesentericischemia.

    Ischemia occurs when blood cannot flowthrough arteries as well as it should, and

    intestines do not receive the necessaryoxygen to perform normally. Mesentericischemia usually involves SMA and smallintestine.

    Mesenteric ischemia primarily affectsorgans which locate far away fromanastomoses with CA & IMA. Usually

    blood supply of the Jejunum and Ileum ismost compromised.

    Mesenteric ischemia typically occurs inpeople older than age 60 with history ofsmoking and high cholesterol level.

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    45. Biliary system & gallstones

    Bile is secreted by the liver cells,stored, and concentrated in thegallbladder and later it isdelivered to the duodenum.

    The gallbladder lies in it’s fossa

    on the visceral surface of theliver right side of quadrate lobe.

    It stores and concentrates bile,which enters and leaves itthrough the cystic duct.

    The cystic duct joins the

    common hepatic (from leftand right hepatic) due to formthe common bile duct.

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    Biliary system

    The common bile duct descends in

    the hepatoduodenal ligament,then passes posterior to the firstpart of the duodenum

    It penetrates the head of thepancreas where it joins the mainpancreatic duct and they form the

    hepatopancreatic ampulla(sphincter of Oddi), which drainsinto posteromedial wall thesecond part of the duodenum at themajor duodenal papilla

    Cholelithiasis (gallstones)

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    Cholelithiasis (gallstones)

    The distal end of the hepato-

    pancreatic ampul la (Bile duct) is the

    narrowest part of the biliary passages

    and is the common si te for impaction

    of gallstones.

     As result of common hepatic (1), bile

    duct (2), or hepatopancreatic

    ampulla (3) obstruction patient will

    have yellow eyes and jaundice

    Gallstones may also lodge in the

    cystic duct. A stone lodged in thecystic duct (4) causes biliary colic

    (intense, spasmodic pain in the

    gallbladder) but doesn't produce

     jaundice.

    1

    2

    3

    4

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    Gallstones

    The fundus [1] of the gallbladder isin contact with the transverse colonand thus gallstones erode through theposterior wall of the gallbladder andenter the transverse colon. They arepassed naturally to the rectum

    through the descending colon andsigmoid colon.

    Gallstones lodged in the body [2] ofthe gallbladder may ulcerate throughthe posterior wall of the body of thegallbladder into the duodenum

    (because the gallbladder body is incontact with the duodenum) and maybe held up at the ileocecal junction,producing an intestinal obstruction.

    2

    1

    46. Nerve supply of the liver

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    and gallbladder 

    Sensory innervation of the liver: by the rightphrenic nerve (C3-C5). Pain may radiate to ther ight shoulder .

    The liver receives parasympathetic innervation

    from the vagi nerves (CNX), reaching it throughthe celiac plexuses around the supplying arteries.The preganglionic fibers synapse on the cells ofthe uxtramural plexuses in hilum of the liver andshot postganglionic fibers supply organs.

    Sympathetic f ibers of preganglionic neurons

    T5-T9 segments (IML) come through thesympathetic trunk and form greater splanchnicnerves. They contribute to the celiac plexus,where postganglionic neurons are located.Branches of celiac plexus reach the liver wrappingaround the branches of the celiac artery.

    47. Portal Hypertension &

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    Portocaval shunts

    Portal hypertension is acommon clinical condition, andfor this reason portal-systemicanastomoses should beremembered.

    [1] Extrahepatic portocavalshunt for the treatment ofportal hypertension: thesplenic vein may beanastomoses to the left renalvein after removing the

    spleen. [2] Intrahepatic portocaval

    shunt : between portal veinand hepatic veins

    Large intestine metastases &

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    Portocaval anastomosis

    Metastases of the Large intestine

    cancer typically rich the Liver via

    portal venous system: Rectum -

    IMV - splenic vein - portal vein -

    Liver

    If there is an obstruction to flowthrough the portal system (portal

    hypertension), blood can flow in a

    retrograde direction and pass

    through anastomoses to reach the

    caval system. Sites for these

    anastomoses include:

    (1) esophageal veins

    (2) paraumbilical veins

    (3) rectal veins

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    Esophageal anastomosis

     Anastomosis between thetributaries of the left gastricvein (portal vein) and thetributaries of the azygousvein (SVC) in the wall of thelower end of the esophagus.

    In portal hypertension theseveins enlarge in the wall of theesophagus and later burstinto the lumen of the

    esophagus (esophagealvarices) resulting inhematemesis (vomiting redblood).

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    Umbilical anastomosis

     Anastomosis between theparaumbilical veins (portalvein) and the superior andinferior epigastric veins(SVC and IVC) in anteriorabdominal wall around theumbilicus.

    In portal hypertension, thisanastomosis gets enlargedand dilated veins form “caputMedussae” around theumbilicus.

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    Rectal anastomosis

     Anastomosis between thesuperior rectal vein(inferior mesenteric veinand then portal vein) andinferior rectal vein whichdrains into the internal iliac

    vein (from IVC system). In portal hypertension

    (chronic alcoholics) thisanastomosis gets dilatedresulting in internalhemorrhoids and bleedingper anus from superior

    rectal vein.

    48. Pancreas:

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    Head and uncinate process

    The head of the pancreasrests within the C-shapedarea formed by theduodenum and istraversed by the commonbile duct.

    It includes the uncinateprocess which is crossedby the superiormesenteric vessels.

    Cancer of the head

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    of the pancreas

    Cancer of the head of thepancreas compresses the bileduct and results inOBSTRUCTIVE TYPE OFJAUNDICE.

    Pain will be conveyed to sensoryneurons T5-T9 dorsal rootganglia via celiac plexus andgreater splanchnic nerve.

    This type of jaundice is NOTusually associated with fever .

    Hepatitis also causes jaundicebut is associated with thefever .

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    Neck of the pancreas

    Posterior to theneck of thepancreas is the siteof formation of thePORTAL VEIN.

    (1)Splenic vein joins with (2)superiormesenteric vein toform (3) portal vein.

    3

    2

    1

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    Body of the pancreas

    The body passes to theleft and anterior to the (1)aorta and the (2) leftkidney.

    The (3) splenic arteryundulates along thesuperior border of thebody of the pancreas withthe splenic vein coursingposterior to the body.

    3

    2

    1

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    Tail of the pancreas

    The tail of the pancreasenters the splenorenalligament to reach thehilum of the spleen.

    It is the only part of thepancreas that isintraperitoneal.

    Tail of the pancreas maybe mistakenly removedduring spleenectomy(ligation of splenic artery

    and vein) and resulting insugar diabetes because itcontains a lot endocrinecells.

     Arterial supply of the

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    pancreas

    Head and Duodenum:

    (1) Superiorpancreaticoduodenal arteries -branches of gastroduodenalartery.

    (2) Inferior pancreaticoduodenal

    arteries - branches of SMA This region is important for

    collateral c irculation becausethere are anastomoses betweenthese branches of the CA andSMA.

    Neck, Body, and Tail of thepancreas:

    Pancreatic branches of the (3)Splenic artery.

    1

    2

    3

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     Annular Pancreas  Annular pancreas is caused by

    malformation during the

    development of the pancreas,

    before birth.

    Occurs when the ventral and dorsal

    pancreatic buds form a ring aroundthe duodenum, thereby causing an

    obstruction of the duodenum and

    polyhydramnios

    Symptoms:

    1. Feeding intolerance in newborns

    2. Fullness after eating

    3. Nausea and bile-stained vomiting

    Half of cases are not diagnosed

    until symptoms occur in adulthood.

    49. Spleen:

    R t f th S l

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    Rapture of the Spleen

    Rapture of the spleen may beresult of the left 9th and 10th ribsfracture or blunt trauma of theleft upper abdomen.

    The spleen is a peritoneal organ

    in the upper left quadrant that isdeep to the left 9th, 10th, and 11th

    ribs.

    The spleen follows the contour ofrib 10 (axis of the spleen).

    When blood collected deep to the

    diaphragm phrenic nerveirritates and pain may irradiate toleft shoulder .

    When spleen is ruptured, itcannot be sutured thereforeremoving is required.

    Relations of the Spleen and

    L ft Kid

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    Left Kidney

    The spleen followsthe contour of 10th riband extends from thesuperior pole of theleft kidney to just

    posterior to themidaxillary line.

    The border betweenspleen and upperpole of the left kidney

    is 11th rib.

    50. Kidney:

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    Dimensions and position

    During life, kidneys arereddish brown and measureapproximately 11-12 cm inlength, 5-6 cm in width, and2.5-3 cm in thickness.

    They are extending from thelevel of T12 to the level of L3,the right kidney lying about2-3 cm lower than the leftone.

    The lateral border of thekidney is convex. Its medial

    border is convex at both endsbut concave in the middlewhere there is the hilum ofthe kidney (L1).

     Anterior relations

    f th i ht kid

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    of the right kidney

    1. Right suprarenal gland

    2. 2nd part of theduodenum

    3. Right lobe of the liver 

    4. Right colic flexure

    5. Small intestine

     Anterior relations

    f th l ft kid

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    of the left kidney

    1. Left suprarenal gland

    2. Stomach

    3. Spleen

    4. Body of pancreas andsplenic vessels

    5. Descending colon

    6. Small intestine

    R l (G t ) f i

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    Renal (Gerota) fascia

    Enclosing the perinephric fat is

    a membranous condensation

    of the extraperitoneal fascia -

    the renal fascia (3).

    The suprarenal glands (4) are

    also enclosed in this fascial

    compartment, usually

    separated from the kidneys by

    a thin septum.

    N.B. The renal fascia must

    be incised in any surgicalapproach to this organ.

    3

    4

    P i h i b

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    Perinephric abscess

    Most infections of the perinephricspace occur as a result of extensionof an ascending urinary tractinfection, commonly in associationwith nephrolithiasis or tuberculosis.

    Perinephric abscess typicallydescends down between 2 sheets ofthe renal fascia along the psoasmajor muscle.

    In case if abscess locates behind ofthe psoas major muscle it descendsdown and may affect hip joint.

    If abscess spreads up it’ll reach thediaphragm and irritate phrenicnerve. As result patient will feel painin shoulder region.

    51 N h lithi i

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    51. Nephrolithiasis

    Renal calculi are solid concretions

    (crystal aggregations) formed in the

    kidneys from dissolved urinary minerals.

    There are several types of kidney

    stones. The majority are calcium

    oxalate stones, followed by calcium

    phosphate stones.

    Kidney stones typically leave the body

    by passage in the urine stream, and

    many stones are formed and passed

    without causing symptoms. If stones grow to sufficient size before

    passage (at least 2-3 mm), they can

    cause obstruction of the ureter (renal

    colic).

    3 t i ti f t

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    3 constrictions of ureter:

    Ureter located on the anteriorsurface of the Psoas majormuscle and has 3 constrictions:

    1st constriction is at thepelviureteric junction (level of L1)

    2d constriction lies at the level ofpelvic brim (level of the sacroiliac

     joint)

    3d constriction appears whereureter lies obliquely in the wall ofurinary bladder (level of ischial

    spine)

    1

    2

    Staghorn calc li

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    Staghorn calculi

    Renal stone that develops in the

    renal pelvis and greater calices,

    and in advanced cases has a

    branching configuration which

    resembles the antlers of a stag.

    Staghorn calculi are composed of

    magnesium ammonium

    phosphate, which forms in urine

    that has an abnormally high pH

    (above 7.2).

    This high pH usually developsbecause of recurrent urinary tract

    infection with microorganisms

    such as Proteus mirabilis.

    52 Suprarenal glands

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    52. Suprarenal glands

    They are endocrine glands

    having cortex and medulla.

    The adrenal cortex [1]

    secretes aldosterone,

    corticosteroids and

    genital hormones.

    1

    2

    The chromaffin cells of the adrenal medulla [2]

    secrete two catecholamines : epinephrine and

    norepinephrine, which affect smooth muscle, cardiac

    muscle, and glands in the same way as sympathetic

    stimulation. Sympathetic stimulation or hypersecretion of

    catecholamines (tumor of adrenal medulla orsympathetic chain ganglia) resulting in: episodes oftachycardia, sweating and high blood pressure.

    Unpaired tributaries of IVC

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    Unpaired tributaries of IVC

    The right renal (1) vein ismuch shorter than the left.Both veins lie anterior to thecorresponding artery inhilum of kidneys.

    The long left renal vein (2)is joined by the leftsuprarenal (3) and leftgonadal (4) (testicular or ovarian) veins before itreached IVC.

    Right suprarenal vein andright gonadal vein draindirectly to IVC (unpairedIVC tributaries).

    1

    2

    3

    4

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    53. Varicocele

    It is enlargement of thepampiniform plexus thatproduces a wormlike scrotalmass and enlargement of thespermatic cord. Varicocelemay be reason of low spermcount.

    Varicocele formation is usuallyon the lef t side and maydisappear in supine positionof the body.

    Varicocele may indicatekidney disease or may signala retro peritoneal malignancyobstructing the testicularvein.

    Pampiniform plexus

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    Each testicular or ovarian vein isformed by coalescence of apampiniform plexus: thetesticular at the deep inguinalring, the ovarian at the margin ofthe superior aperture of the

    pelvis. The veins run accompanied by

    the corresponding arteries. Theleft pampiniform plexus entersthe left renal vein; the right oneenters directly the IVC inferiorto the renal vein.

    That is why varicocely(engorgement of the pampiniformplexus that produces a scrotalmass) is more often located onthe left.

    54 Hydrocele

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    54. Hydrocele

    The tunica vaginalis testis orother remnants of the processusvaginalis may form a hydroceleor hematocele.

    In spermatic cord it is smooth

    sausage-shaped structure thatpersists under gentlecompression and isn’t disappearin supine position.

    In the scrotum withtransillumination, a hydroceleproduces a reddish glow,

    whereas light will not penetrateother scrotal masses such as ahematocele, solid tumor , orherniated bowel.

    55. Hemorrhoids:

    V d i f t

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    Venous drainage from rectum

     Above pectinate line: superior

    rectal vein [1] into portal

    system [2].

    Below pectinate line: inferior

    rectal vein [3] into inferior

    vena cava [4].

    1

    2

    3

    4

    E t l h h id

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    External hemorrhoids

    Hemorrhoids are masses that

    typically protrude from anus

    during defecation.

    Hemorrhoids are commonly

    associated with constipation,extended sitting and straining at

    the toilet, pregnancy, and

    disorders that hinder venous return.

    1. External hemorrhoids are

    dilated tributaries of the inferior

    rectal veins (IRV) BELOW THE

    PECTINATE LINE and are painful

    because the mucosa is supplied by

    somatic afferent fibers of the

    inferior rectal nerves (from

    pudendal).

    1

    1

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    Internal hemorrhoids

    2. Internal hemorrhoidsare dilated tributaries of thesuperior rectal veins(SRV) ABOVE THE

    PECTINATE LINE and arenot painful because themucosa is supplied byvisceral afferent fibers.

    Internal hemorrhoids

    frequently develop inchronic alcoholicsbecause of liver cirrhosisand portal hypertensionsyndrome.

    2

    2

    2

    56. Perineal pouches:

    Deep perineal pouch

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    Deep perineal pouch

    The deep perineal pouch is

    formed by the fasciae and

    muscles of the urogenital

    diaphragm.

    It contains:1. Sphincter urethrae

    muscle

    2. Deep transverse

    perineal muscle

    3. Bulbourethral

    (Cowper ) glands (inthe male only) - ducts

    perforate perineal

    membrane and enters

    bulbar urethra.

    Superficial perineal pouch1 I hi l l t d t th C f th

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    1. Ischiocavernosus muscle – related to the Crus of thepenis (Male) & Crus of the clitoris (Female)

    2. Bulbospongiosus muscle – related to the Bulb ofvestibule (Female) & Bulb of the penis (Male)

    3. Superficial transverse perineal muscle – related to thePerineal body (both genders)

    1

    2

    3

    Urine leaks

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    Urine leaks

     After a crushing blow or a

    penetrating injury, the spongy

    urethra commonly ruptures

    within the bulb of the penis, and

    urine leaks into the superficialperineal pouch.

    The superficial perineal fascia

    keeps ur