1 st year mbbs study guide - cmh lahore medical and dental ...€¦ · ovulation & implantation...
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1
1st Year MBBS
STUDY GUIDE
CMH Lahore Medical College & Institute of
Dentistry
2
MBBS ANATOMY PROGRAMME AT NUMS
Vision: To train undergraduate students by qualified faculty and state of the art infrastructure and technology so that students can meet the community challenges of 21st century.
Mission: To impart core knowledge of anatomy in interesting, compact and practical way to undergraduate students by Hybrid/Spiral integrated system of teaching so that they can differentiate between normal and abnormal structure at gross, microscopic and embryological level.
Objectives: For this we need to impart: Knowledge of Anatomy - On principles of pedagogy Skills Dissection & Prosection
Simulation – Models Cyber teaching Surface Anatomy Modern Histological techniques
Attitude: Communication Skills
- Lecture & Presentation Self directed learning
- CBL, Museum Atlas - Integrated Journal - Cyber Teaching - E-Learning
Quest for Research - Journal club meeting
- Library Professionalism
Empathy Inter Personal Skills Extra Curricular activities
3
Contents
Description Page No
List of Faculty 4
Overview 5
Time Table 6
Block –I 7
Block – II 16
Block – III 30
Table of Specifications 43
List of Recommended Books 44
4
List of Faculty
Dr. Nazreen Sharif Professor & Head of Department
Dr. Ansa Rabia Professor
Dr. Shaista Arshad Jarral Associate Professor
Dr. Tayyaba Mahmud Assistant Professor
Demonstrators
Dr. Ayesha Taimur
Dr. Yumna Muzaffar
Dr. Arwa Khawar
Dr. Falaq Shahid
Dr. Saman Rauf
Dr. Sarah Ismail
Dr. Hammad Ali
5
Overview
Module No
Subject
Teaching & Learning
Evaluation
Block-I (14 Weeks)
Gross Anatomy Upper Limb 3 Substages *EOB - I
General Anatomy General anatomical
terms Bone
Joints Muscular system
Nervous system-I
(Introduction)
*EOB - I
Embryology Mitosis and meiosis,
Gametogenesis
Ovulation &
Implantation 1st week of
development 2nd week
of development 3rd
week of development
*EOB - I
Histology Cell (Introduction,
staining, cytoskeleton,
cell junctions)Surface
and glandular
epithelium Connective
tissue (General)Bone
Cartilage Muscle
*EOB - I
Block-II (10 Weeks)
Gross Anatomy Thorax 2 Substages *EOB - II
Embryology Embryonic period,
Fetal period
Placenta and fetal
membranes Twining
CVS
*EOB – II
Histology Circulatory System
Immune system *EOB – II
General Anatomy Lymphatic system
Circulatory system
*EOB - II
Block-III (10 weeks)
Gross Anatomy Lower Limb 3 Substages *EOB – III
General Anatomy Skin Fascia Vertebral
column Nervous system-
II
*EOB - III
Embryology Birth defects Body
cavities
Respiratory system
Muscular System
Skeletal system except
head and neck
Development of limbs
*EOB - III
Histology Respiratory system *EOB - III
6
Pre Prof / Send-up exam
*EOB – End of Block Exam
7
8
Block-I
Anatomy
9
COURSE CONTENTS, PROPOSED LEARNING OBJECTIVES
SUGGESTED MIT (mode of information transfer)
Summary
Code MODULE - I
Name Anatomy
Duration 14 weeks
Broad Themes of Module
(Theme: a subject that is being
integrated a majority of time of module)
Introduction 2. Cells and genetics 3. Blood 4. Loco motor (Upper limb)
Subject Themes
Gross anatomy
Upper limb
General Anatomy
General anatomical terns
Bone Joints Muscular system Nervous system-I (Introduction)
Embryology
Mitosis and meiosis, Gametogenesis
Ovulation &Implantation
1st week of development
2nd week of development
3rd week of development
Histology
Cell(Introduction, staining, cytoskeleton, cell junctions)
Surface and glandular epithelium
Connective tissue(General)
Bone Cartilage
Muscle Prerequisite Module None
Mode of Information Transfer:
MIT
Lectures
Dissection
Demonstration
CBL
Practical
Dissection movies
10
GROSS ANATOMY
Topic Learning Objectives Students should be able to:
MIT (Mode of information transfer)
GROSS ANATOMY UPPER LIMB
Identify important bony land marks of Scapula
Describe the attachment of muscles& ligaments of Scapula
Identify important bony land marks of Clavicle
Describe the attachments of muscles and ligaments of clavicle.
Identify important bony land marks of Humerus.
Identify the different types of fractures of humerus and nerve injuries
Describe the attachment of muscles & ligaments of Humerus
Identify important bony land marks of radius &Ulna.
Describe the attachments of muscles & ligaments of radius and Ulna
Identify the common sites of fractures of radius &Ulna.
LGIS/ Demo
Bones of upper limb
Breast Knowledge
Discuss the structure and divisions of breast tissue
Discuss importance of fibrous septa
Discuss its blood supply and venous drainage
Discuss lymphatic drainage of each quadrant of breast
Discuss the importance of sentinel lymph node
Describe supernumerary and retracted nipples Describe breast abscess and CA breast
LGIS/ Demo
Scapular region Knowledge
Describe muscles connecting the upper limb to thoracic wall
Describe muscles connecting the scapula to humerus
Discuss origin insertion, nerve and blood supply of these muscles
Identify the boundaries of quadrangular and triangular spaces
Identify structures present in these spaces
Discuss arteries and nerves present in this region Skill
Study prosected specimen and identify the muscles of this region
LGIS/ Demo
Acromioclavicular Knowledge
Describe formation, ligaments and articulation of these joints
Discuss scapulohumeral mechanism
Discuss blood supply and nerve supply of these joints Discuss injury and dislocation of these joints
and
sternoclavicular LGIS/ Demo
joint
Shoulder joint Knowledge
Describe movements, ligaments, nerve supply & blood supply of Shoulder joint
Describe arterial anastomosis around shoulder joint Describe the Dislocation of shoulder joint
LGIS/ Demo
Anatomy learning outcomes:
11
Explain Rotator Cuff & enumerate the injuries to it.
Discuss rotator cuff tendinitis
Describe rupture of supraspinatus tendon
Discuss dislocation of shoulder joint
Discuss shoulder pain
Skill
Perform movements of shoulder joint
Study the model of shoulder joint and mark its ligaments and
rotator cuff muscles around it
Axilla Knowledge
Describe the boundaries & contents of Axilla
Describe the relation of cords of brachial plexus
Describe injury to the Axillary Vein and artery
Describe axillary lymph nodes, their location, division and
area of drainage
Discuss lymphangitis and lymphadenitis
Describe the importance of axillary lymph nodes in CA
breast Skill
Study prosected specimen and models of axilla
LGIS/ Demo
Arm Knowledge
Discuss anterior and posterior compartment of arm and
structures present in it
Discuss origin, insertion of muscles of anterior and posterior
compartment of arm
Discuss blood supply and nerve supply of these
compartments Skill
Study the models and prosected specimen of arm and
identify the structures present in this region.
LGIS/ Demo
Elbow joint
Proximal and
distal
radioulna
r joints
Knowledge
Describe the type, capsule and ligaments of these joints
Discuss the movements of these joints
Discuss muscles performing these movements
Discuss blood supply and nerve supply of these joints
Describe the anatomical significance of carrying angle
Discuss dislocation and clinical correlation of these joints
Discuss structures getting damaged in elbow
joint dislocation Skill
Perform movements at elbow joint and discuss the muscles
involved in these movements
Study the models of elbow joint and recognize the bones and ligaments forming the joint
LGIS/ Demo
Cubital fossa Describe the boundaries of cubital fossa
Enlist the contents of cubital fossa and their arrangement
Discuss the importance of structures present in cubital fossa Skill
Mark the boundaries and contents of cubital fossa on a
model
LGIS/ Demo
12
Forearm Knowledge
Discuss contents of anterior lateral and posterior fascial
compartments of forearm
Discuss muscles of these compartments and their blood
supply
Discuss the course of nerves and arteries present in this
region
Discuss boundaries of anatomical snuff box and its
importance
Describe flexor and extensor retinaculum
Discuss clinical correlations of this compartment including
tennis elbow Skill
Study prosected specimen of forearm and identify muscles,
blood vessels and nerves present in this region
Study the models of forearm and discuss origin and insertion
of muscles Mark the extensor and flexor retinacula on the model
LGIS/ Demo
The region of
wrist and palm of
hand
Knowledge
Discuss bones of Hand
Describe functions of muscles in Thenar, Hypothenar &
Central compartments
Describe the fibrous sheaths of the digits of the hand
Discuss the anatomical structures involved in Tenosynovitis
Describe Palmar aponeurosis
Enumerate fascial spaces of Palm
Describe boundaries & contents of spaces of palm
Discuss clinical importance of spaces of palm
Discuss wrist joint
Explain the movements at wrist joint
Discuss ligaments of wrist joint and its relations
Discuss the anatomical structures involved in Wrist fractures
Explain the formation of Carpal tunnel and its contents
Explain the Carpal tunnel syndrome
Describe the course & branches of nerves in Hand
Discuss metacarpophalangeal and interphalangeal joints of
hand Skill
Perform movements of wrist joint and recognize the muscles
involved in these movements
Study the model of hand to visualize muscles of hand and
insertion of long tendons
Study prosected specimen of hand to identify muscles and
blood vessels of hand.
LGIS/ Demo
Nerves of upper
limb & brachial
plexus
Knowledge
Describe formation of Brachial Plexus with emphasis on
Cords, Roots & trunk
Discuss injuries of the brachial plexus:
Klumpke paralysis & Erb-Duchenne palsy
Describe formation, distribution & important relations of following nerves:
LGIS/ Demo
13
Axillary nerve Musculocutaneous nerve Median nerve Radial nerve Ulnar nerve Describe the innervation of each compartment and the specific deficits that occur with lesions of individual nerves at different parts along the course of following nerves: Musculocutaneous nerve Median nerve Radial nerve Ulnar nerve discuss the anatomical sites of lesion of nerve correlating them to sensory and motor loss within area of distribution
Cutaneous nerves of upper limb
Knowledge
Describe the cutaneous innervation of the arm, forearm and hand.
Compare and contrast dermatomes with the cutaneous innervation of specific nerves in Arm & forearm
Skill
Draw & label cutaneous innervation of lower limb
Draw & label the dermatomes of lower limb
LGIS/ Demo
Blood supply of upper limb
Knowledge
Discuss the course, extent & branches of Axillary, Brachial, Ulnar and Radial arteries
Describe the anatomical sites of lesion of artery correlating them to ischemia within area of distribution
Describe the formation of Superficial and Deep Palmar Arches in hand
Describe the structures involved in Laceration of Palmar Arches
Describe the formation & drainage of following Veins:
Axillary vein
Basilic vein
Cephalic vein
Median cubital vein
Discuss the importance of Median Cubital Vein in
venipuncture
LGIS/ Demo
Lymphatic drainage of upper limb
Discuss the lymphatic drainage of upper limb in detail
LGIS/ Demo
DISSECTION Perform dissection to identify main muscles of scapular region along with their nerve supply Perform dissection to identify main muscles of arm along with their nerve supply Perform dissection to identify main muscles of forearm along with their nerve supply. Perform dissection to identify main muscles of hand along with their nerve supply Perform dissection to identify muscles forming boundaries of cubital fossa
Dissection
14
Perform dissection to identify contents of cubital fossa
IMAGING Identify the common sites of fracture on radiographs correlating its
predisposition to fracture in the following bones:
Scapula
Clavicle
Humerus
Radius
Ulna Identify the bones and bony articulations of upper limb on AP and
Lateral view of Radiographs
Demo
EMBROLOGY
MITOSIS & MEIOSIS Define Meiosis
Differentiate first and second meiotic divisions.
State the phases of meiotic divisions.
Justify the importance and result of meiosis in both sexes
Differentiate between mitosis and meiosis.
Describe the structure abnormalities in chromosomes like
Euploid, Aneuploid, Trisomy, Non-disjunction, Translation
Correlate the structure abnormalities with clinical conditions
like: Down’s syndrome Klinefelter and Tuner syndromes
LGIS
GAMETOGENESIS-I Describe the events of spermatogenesis.
Describe the morphological changes during maturation of the
gametes
Enlist the differences between spermiogenesis and spermatogenesis
GAMETOGENESIS-II Define the ovarian cycle
Describe the stages of follicular maturation primary preantral,
secondary, preovulatory, Explain the hormonal control (FSH,
LH) of ovarian cycle Discuss the transport of ovum from the surface of ovary to
ampulla of fallopian tube
LGIS
OVULATION &
IMPLANTATION
Define fertilization
State normal site of fertilization
Describe the results of fertilization Mentions the factors affecting fertilization
Enumerate the changes that occur in spermatozoa before
fertilization
Explain the factors affecting penetration of sperm through the
zona pellucida for formation of Pro nuclei Discuss the formation of zygote
Correlate the transport of zygote from ampulla of fallopian tube
to the uterine cavity and cleavage Explain the formation of blastocyst
LGIS
1ST WEEK OF
DEVELOPMENT
Explain the formation of outer and inner cell masses
Discuss the further development of outer cell mass
(trophoblast),
Differentiate syncytiotrophoblast and cytotrophoblast with its
microscopic appearance Describe the process of implantation (day wise change)
LGIS
15
2ND WEEK OF
DEVELOPMENT
State the differentiation of embryonic pole and development of
bilaminar germ disc with formation of Epiblast and hypoblast,
their cavities (amniotic cavity and primary yolk sac) Discuss the
development of the chorionic sac and formation of primary
chorionic villi and growth of syncytiotrophablast Explain the establishment of utero placental circulation Explain
why the second week is known “ as week of two’s”
LGIS
3RD WEEK OF
DEVELOPMENT
Define gastrulation (formation of three germ layers)
Discuss the development of primitive streak and related
congenital anomalies (Sacrococcygeal teratoma)
Describe the development of notochordal process, notochord
canal, prechordal plate and cloacal membrane
Define Neurulation
List the steps of development of Neural Tube
Enumerate the derivatives of Neural Crest Cells
State the congenital anomalies resulting from abnormal
neurulation
Describe the formation of three germ layers and enlist their
derivatives
Differentiate three components of Mesoderm (Paraxial,
Intermediate and Lateral Plate Mesoderm) Define Somites
LGIS
HISTOLOGY
CELL
(INTRODUCTION,
STAINING,
CYTOSKELETON,
CELL JUNCTIONS)
KNOWLEDGE
Identify parts of Light Microscope
Discuss the working & magnification of Light Microscope
Identify different types of Microscopes and their functions
Define resolution
Describe the steps involved in tissue processing Define
cell, identify various types of cells and shapes Define
Cytoskeleton.
Enumerate the cell junctions and describe their histological
structure SKILL
Identify and draw the different parts of microscope and
illustrate their usage.
Focus the prepared slide at different magnifications. Identify
the different shapes of cells and their examples Draw a
labelled diagram of different types of shapes of cells
LGIS
Lab
SURFACE
& GLANDULAR
EPITHELIUM
Classify the body tissue into categories
Define Epithelium Classify various types of Epithelium
Discuss general features of Epithelial cells (basal, apical and
lateral surfaces)
Explain the different types of epithelium with examples
Describe glandular epithelium
Differentiate the structure of serous and mucus secreting
cells SKILL
Identify the different types of Epithelia and their examples
Draw a labelled diagram of different types of simple and
stratified epithelia
LGIS
Lab
16
Identify mucous and serous acini with haematoxylin and
eosin Draw a labelled diagram of mucous and serous acini with haematoxylin and eosin
CONNECTIVE TISSUE
(GENERAL)
KNOWLEDGE
Explain the components of connective tissue Describe
different types of cells in connective tissue Describe
different types of fibers in connective tissue Discuss
various constituents of ground substance Classify
various types of connective tissues
Describe the histology of different types of adipose tissue
SKILL
Identify the microscopic structure of loose connective tissue,
dense regular and irregular connective tissue
Draw a labeled diagram showing the microscopic structure of
loose connective tissue, dense regular and irregular connective
tissue with haematoxylin and eosin
Draw a labeled diagram of the connective tissue
wit
h haematoxylin and eosin
LGIS
Lab
BONE KNOWLEDGE
Describe microscopic features of bones and types of ossification
Enlist the location of different types of bones
SKILL
Identify different types of bone microscopically
Draw a labelled diagram showing the histological structure of
different types of bone with hematoxylin and eosin
LGIS
Lab
CARTILAGE KNOWLEDGE Describe microscopic features of various types of cartilage SKILL
Identify different types of cartilage microscopically
Draw a labeled diagram showing the histologic structure of different types of cartilage with hematoxylin and eosin
LGIS
Lab
MUSCLE KNOWLEDGE
Describe the microscopic features of skeletal, smooth and
cardiac muscle SKILL
Identify the different types of muscle microscopically
Draw a labeled histological diagram of different types of muscles with hematoxylin and eosin
LGIS
Lab
List of Histology Practical’s- 1st Year MBBS Class first module
Topic
Histology and Its Methods of Study
Epithelial Tissue
Connective Tissue
Muscle tissue
Bone
Cartilage
17
Block-II
Anatomy
18
COURSE CONTENTS, PROPOSED LEARNING OBJECTIVES
SUGGESTED MIT (mode of information transfer)
Summary
Code MODULE - II
Name Anatomy
Duration 10 weeks
Broad Themes of Module
(Theme: a subject that is being
integrated a majority of time of
module)
1.Thorax
2.Cardiovascular system
Subject Themes
Gross anatomy
Thorax
Embryology
Embryonic period, Fetal period
Placenta and fetal membranes
Twining
CVS
Histology
Circulatory System
Immune system
General Anatomy
Lymphatic system
Circulatory system
Prerequisite Module Y1M1
Mode of Information Transfer:
MIT
Lectures
Dissection
Tutorials (PTT)
CBL
Practicals
Class tests
19
Anatomy learning outcomes
Anatomy
PROPOSED LEARNING OBJECTIVES AND SUGGESTED MITs (mode of
information transfer)
GENERAL ANATOMY
S.NO. TOPICS LEARNING OBJECTIVES MIT
Circulatory
System
Discuss the general structural plan of
blood vessels.
Classify blood vessels on anatomical and
functional basis
Explain each type of blood vessel and give
examples
Discuss general plan of systemic,
pulmonary and coronary circulatory
system.
Discuss general plan of portal system with
brief accounts of arterial and venous
portal systems giving examples.
Differentiate between anatomic end
arteries and functional end arteries giving
examples
Define anastomosis; describe various
types of anastomosis with examples and
their clinical significance.
Describe blood supply of arteries and
veins.
Explain the importance of collateral
circulation
LGIS
(Large
group
interactive
session)
Lymphatic
System
Discuss general plan of the lymphatic
circulatory system of the body.
Explain the mechanism of formation and
flow of lymph.
Enumerate the factors responsible for
flow of lymph.
Discuss the structural plan of lymphatic
vessels.
Describe the structural plan of lymph
nodes and their role in lymphatic system
Enumerate the capsulated
lymphoid
organs
LGIS
20
Correlate the role of lymphatic system
with spread of cancer and infection.
Correlate the role of lymphatic system
with development of edema.
HISTOLOGY
Circulatory
System
KNOWLEDGE:
Discuss the general histological plan of
blood vessels.
Describe and compare the histological
structure of:
Elastic artery
Muscular artery
Arteriole
Different types of Capillaries
Venule
Medium sized vein
Large vein
Describe histological changes in intima in
atherosclerosis or arteriosclerosis
SKILLS:
Identify elastic artery, muscular artery and
large vein under light microscope and
enlist at least two identification points for
each.
Draw labelled diagram of elastic artery,
muscular artery and large vein with the
help of eosin and hematoxylin pencils on
the histology notebook
LGIS
Lab
Immune
System
KNOWLEDGE:
Enumerate the cells of immune system.
Describe the structure of primary and
secondary lymph nodule.
Describe the histological features of:
Lymph node
Thymus
Spleen
Tonsils
Compare the histological structure of
thymus, lymph node, spleen and tonsils.
SKILLS:
Identify slides of lymph node, thymus,
spleen and palatine tonsils under light
microscope and enlist at least two
identification points for each.
LGIS
Lab
21
Draw labelled diagram of lymph node,
thymus, spleen and palatine tonsils with
the help of eosin and hematoxylin pencils
on the histology notebook
EMBRYOLOGY
KNOWLEDGE
Embryonic
period
(3rd to 8th week)
Define neurulation
Describe process of formation of neural
plate, neural tube and neural crest cells.
Enlist derivatives of:
Surface ectoderm
Neurectoderm
Neural crest
Intraembryonic mesoderm (paraxial,
intermediate, lateral plate)
Endoderm
Describe somitogenesis and early
differentiation of somites.
Describe the development of
intraembryonic coelom
Describe the folding of the embryo in the
longitudinal plane and correlate it with its
consequences
Describe the folding of the embryo in the
horizontal plane and correlate it with its
consequences
Describe relocation of connecting stalk to
the anterior abdominal wall and its
differentiation into umbilical cord.
Describe the process of formation of blood
and blood vessels and differentiate
between angiogenesis and
vasculogenesis
Explain the embryological basis of the
neural tube defects like anencephaly and
spina bifida
Define hemangioma and explain its
embryological basis
LGIS
Fetal period
(third month to
birth)
Define fetal period
Enumerate various methods to estimate
fetal age
Describe factors affecting fetal growth
LGIS
22
Enlist the external body landmarks from
third month to birth
Define intrauterine growth retardation
Placenta and
fetal
membranes
Enlist types of chorion and give fate of
each.
Enlist types of decidua and give fate of
each.
Enumerate the fetal and maternal
components of placenta.
Differentiate between stem, anchoring and
terminal villi
Enumerate the layers forming placental
barrier
Describe placental circulation (maternal
and fetal)
Enumerate functions of the placenta Enlist
the features of maternal and fetal surfaces
of placenta.
Enumerate placental changes by the end
of pregnancy
List fetal membranes and their functions
Describe production, circulation and
significance of the amniotic fluid.
Describe the development of umbilical cord
Define preeclampsia and correlate it with
trophoblastic differentiation
Describe the embryological basis of
amniotic bands, umbilical cord defects,
erythroblastosis fetalis and hydrops fetalis
Define poly and oligohydramnios.
Enumerate their embryological causes and
adverse effects
LGIS
Twining
Name two basic types of twins.
Describe the mechanism behind
occurrence of dizygotic & monozygotic
twins.
Discuss the possible arrangements of fetal
membranes in case of monozygotic twins.
Discuss fetus papyraceus, twin
transfusion syndrome and conjoined
LGIS
23
twins on basis of knowledge of
embryology
CVS-I
(Heart)
Explain the formation of heart tube.
Describe the mechanism of cardiac
looping
Enlist the parts of heart tube and their
definitive derivatives
Explain the embryological basis of
dextrocardia
Describe histogenesis of heart
Describe contribution of bulbs cordis and
sinus venosus to the development of heart
Explain different methods of septal
formation
Describe division of atrioventricular canal
Explain the embryological steps involved
in formation of interatrial septum
Correlate the internal differentiation of
right atrium with internal structure of
right atrium of definitive heart
Describe the formation of left atrium and
pulmonary veins
Explain the division of conotruncus
Describe the formation of interventricular
septum and identify sources of
its different parts
Describe the development of valves of
heart
Describe the development of conducting
system of heart
Explain the embryological basis of the
following heart defects:
Various forms of atrial septal defects
Ventricular septal defects
Fallot’s tetralogy
Transposition of great vessels
Persistent truncus arteriosus
Pulmonary stenosis
Aortic stenosis
Tricuspid atresia
Hypertrophic right and left heart
syndromes
LGIS
24
Ectopia cordis
CVS-II
(Arteria
l
system)
Define aortic arches
Explain the development and fate of aortic
arches
Enumerate the developmental sources of
aorta
Justify the relationship of recurrent
laryngeal nerves on the basis of your
knowledge of embryology
Enumerate the segmental branches of
dorsal aortae & give their fate
Explain the fate of vitelline & umbilical
arteries
Explain the development of arteries of the
limbs
Enumerate & explain the congenital
anomalies of arterial system which
include:
Patent Ductus Arteriosus
Coarctation of aorta
Double aortic arch
Right aortic arch
Abnormal origin of the Right Subclavian
Artery
An interrupted aortic arch
LGIS
CVS-III
(Venous
system)
Explain the fate of vitelline, umbilical and
cardinal veins
Explain the development of inferior vena
cava
Explain the development of superior vena
cava
Correlate following anomalies of venae
cavae with their development
Double Inferior Vena Cava
Absence of Inferior Vena Cava
Left Superior Vena Cava Double
Superior Vena Cava
Explain the development of lymphatic
system
LGIS
25
CVS-IV
(Fetal
circulation
)
Describe fetal circulation
Describe following fetal
circulatory changes at birth:
Closure of the umbilical vein and ductus
venosus
Closure of the ductus arteriosus
Closure of the oval foramen
LGIS
SKILLS
Embryology
Identify the structures related to general
development and development of
cardiovascular system on given models
and diagrams
SGD
(Small
group
discussion)
GROSS ANATOMY
THORAX
KNOWLEDGE:
Thoracic wall
(Bones and soft
parts)
Enumerate the bones contributing in
thoracic cage
Describe the bony framework of the
thoracic cage with topographic placement
of each bone
Identify structures forming the thoracic
inlet and outlet/costal margin
Discuss sternum, with reference to its parts
and attachments
Define sternal angle and discuss its
importance in clinical practice
Classify ribs into true and false
Determine side of ribs
Discuss parts of a typical rib
Differentiate between typical and atypical
ribs
Identify typical thoracic vertebra, describe
its different parts and identification points
Compare a typical and atypical thoracic
vertebra
Describe the joints of thorax
with reference to their types and
movements Discuss and differentiate
between the pump handle and
bucket handle movements and
their effect on diameters
of chest cavity
SGD and
dissection
26
Discuss the role of the accessory
respiratory muscles during inspiration
and expiration
Enlist the contents of a typical intercostal
space including muscles, nerves and
vessels
Describe the attachments, actions and
nerve supply of thoracic muscles Discuss
the arterial supply and venous drainage of
the thoracic wall.
Discuss the course and distribution of a
thoracic spinal nerve
Identify and justify the most suitable site
for an invasive procedure in an intercostal
space
Analyze the clinical scenario related to
blunt chest trauma and its complications
with anatomical reasoning
Diaphragm
Describe the parts, attachments and nerve
supply of diaphragm
Enlist the apertures in diaphragm with
their levels and structures passing
through each
Discuss the role of diaphragm and scalene
muscles in increasing the vertical diameter
of thoracic cavity
Analyze the clinical scenario related to
diaphragmatic hernia and phrenic nerve
lesions with anatomical reasoning
Correlate the tip of shoulder pain with
irritation of diaphragm
SGD and
dissection
Pleura
Enumerate and discuss various parts of
pleura and identify their locations
Describe the pleural reflections and
recesses
Describe the innervation of the visceral and
parietal layers of the pleura
Discuss the clinical significance of
reflections and recesses of pleura and
pleural cavity
Define pleural effusion, pneumothorax,
empyema and hemothorax
SGD and
dissection
27
Enlist the anatomical structures
encountered in chest tube insertion
Lungs
Identify the side of lungs
Enlist borders and surfaces of lungs
Discuss the topographic arrangement of
structures in hilum of each lung
Discuss the blood supply, nerve supply ,
lymphatic drainage and relations of
various surfaces of both lungs
Define bronchopulmonary segments.
Enlist them in each lung. Discuss their
significance.
Discuss with anatomical reasoning, the
clinical presentation of bronchogenic
carcinoma and lung trauma
SGD and
dissection
Mediastinum
(General
outline)
Define mediastinum
Describe how the mediastinum is further
divided
Enlist the structures lying at the level of
transverse thoracic plane
Outline the boundaries of each division of
mediastinum
Enumerate contents of each division of
mediastinum
SGD and
dissection
Anterior
mediastinum
Outline the boundaries of
anterior mediastinum
Enumerate the contents of
anterior mediastinum
Describe the shape, relations and blood
supply of thymus
SGD and
dissection
Superior
mediastinum
Outline the boundaries of superior
mediastinum and describe its general
topography
Enumerate the contents of
superior mediastinum
Identify carina at the site of bifurcation of
trachea into main principal bronchi
Describe immediate relations, blood and
nerve supply of thoracic part of trachea
SGD and
dissection
28
Justify the right bronchus being the most
probable site of foreign body impaction in
respiratory tract
Describe the orientation, relations and
branches of arch of aorta
Describe the formation, relations and
tributaries of superior vena cava and
brachiocephalic veins
Determine the site of ligamentum
arteriosum and its relation to left recurrent
laryngeal nerve
Describe the origin, course, relations and
distribution of both phrenic nerves
Analyze the clinical scenarios related to
compression of trachea and
damage/irritation of phrenic nerve based
upon your knowledge of Anatomy
Posterior
mediastinum
Outline the boundaries of posterior
mediastinum and describe its general
topography
Enumerate the contents of posterior
mediastinum
Describe the relations and branches of
descending aorta
Describe the course, relations and
constrictions of thoracic part of esophagus
Discuss the reason behind esophageal
varices in case of portal hypertension
Describe the thoracic duct with reference
to its formation, course,
tributaries, termination and area of
drainage Analyze the clinical scenarios
related to chylothorax with the help
of your knowledge of Anatomy
Describe the course, relations and
distribution of both vagus nerves in thorax
Discuss the azygos system of veins with
reference to formation, course, relations,
tributaries and area of drainage of both
azygos and hemiazygos veins
Discuss the role of azygos vein in case of
caval obstruction
SGD and
dissection
29
Identify the lymph nodes in the posterior
mediastinum
Define splanchnic nerves and identify the
location of thoracic sympathetic chain
Pericardium
Enumerate various layers of pericardium
Describe the gross features of fibrous
pericardium
Describe the gross features of serous
pericardium (both parietal and visceral
layers)
Describe the reflections of parietal and
visceral pericardium resulting in formation
of transverse and oblique sinuses Identify
the locations of
pericardial sinuses
Describe the surgical significance of the
Transverse Pericardial Sinus
Discuss the innervation of various layers
of the pericardium
Define pericarditis and pericardial
effusion
Identify the best location for and enlist the
anatomical structures encountered
in pericardiocentesis
SGD and
dissection
Heart
Describe anatomical position, borders,
surfaces, apex and base of heart Describe
external features of the heart Describe
internal structure of various chambers of
heart
Compare the functional anatomy of right
and left ventricles
Describe structure of various valves of
heart
Enumerate the structures comprising the
cardiac skeleton and describe its
significance
Describe the arterial supply of heart
Explain the basis of right or
left dominance of heart
Describe the venous drainage of heart
Describe nerve supply of heart
Define angina pectoris, myocardial
infarction and cardiac tamponade
SGD and
dissection
30
Describe variations of coronary arteries in
context of myocardial infarction
Justify the chest pain, left upper limb pain,
jaw pain and epigastric discomfort as
presenting complaint of ischemic heart
disease with anatomical reasoning
SKILLS:
Gross Anatomy
of Thorax
Identify muscles, bones, ligaments, nerves,
vessels, organs and their parts located in
thorax:
on a cadaver after performing dissection
on prossected specimens
on provided models
SGD and
dissection
Surface
marking
Identify the important bony landmarks of
thorax and mark them on a subject.
Mark the borders of lungs, pleural
reflections, borders and apex of heart,
valves of heart, thoracic duct, esophagus,
trachea, main vessels and nerves of
thorax on the given subject
SGD and
Skills lab
Imaging of
head and neck
Identify the bones of thorax, aortic
knuckle, borders of heart, lungs, trachea,
hilar shadows, diaphragm and its recesses
on chest radiographs
SGD and
skills lab
List of Practical Histology (Anatomy):
Cardiac muscle
The Circulatory System-I
The Circulatory System-II
The Circulatory System-III
31
Block-III
Anatomy
32
COURSE CONTENTS, PROPOSED LEARNING OBJECTIVES
SUGGESTED MIT (mode of information transfer)
Summary
Code MODULE - III
Name Anatomy
Duration 10 weeks
Broad Themes of Module
(Theme: a subject that is being
integrated a majority of time of
module)
Lower Limb
Respiratory System
Subject Themes
Gross anatomy
Lower Limb
General Anatomy
Skin Fascia
Vertebral column
Nervous system-II
Embryology
Birth defects
Body cavities
Respiratory system
Muscular System
Skeletal system except head and neck
Development of limbs
Histology
Respiratory system
Prerequisite Module Y1M1 & Y1M2
Mode of Information Transfer:
MIT
Lectures
Dissection
Tutorials (PTT)
CBL
Practicals
Class tests
33
Anatomy learning outcomes:
ANATOMY
LEARNING OUTCOMES
S.
N
TOPIC DISCI-
PLINE
MIT LEARNING OUTCOMES
1 Hip bone Gross
Anatomy
SG
D
Skill:
Demonstrate the anatomical position of bone and
determine the side
Recognize important bony land marks on gross
inspection as well as on radiographs
Identify the muscles & ligamentous attachments on
bone
Knowledge:
Describe the muscles & ligamentous attachments on
bone
Discuss injuries of hip bone and identify them on
radiographs
Compare gender differences of hip bone
2 Gluteal Region Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of
gluteal region of the cadaver after performing
dissection.
Knowledge:
Describe in tabulated form the origin, insertion,
nerve supply and action of gluteal muscles
Enumerate structures deep to gluteus maximus
Describe boundaries of greater sciatic and lesser
sciatic foramina and enumerate structures
passing through them
Summarize the origin, relations and main
branches of nerves and vessels of gluteal region
Analyze clinical scenarios regarding:
Injury to superior gluteal nerve
Injury to inferior gluteal nerve
Injury to sciatic nerve
Intragluteal injections
3 Femur Gross
Anatomy
SG
D
Skill:
Demonstrate the anatomical position of bone and
determine the side
Recognize important bony land marks on gross
inspection as well as on radiographs
Knowledge:
34
Describe the muscle & ligamentous attachments on
bone
Describe femoral fractures and identify them on
radiographs
Analyze clinical scenarios related with coxa vera
and coxa valga
Analyze clinical scenarios related with interruption
of blood supply to head & neck of femur
4 Anterior fascial
Compartment of
Thigh
Gross
Anatomy
SG
D
Skill:
Dissect the front of thigh to:
Trace continuity of fascial layers of abdominal wall
with perineum & thigh
Explore the arrangement of superficial inguinal
lymph nodes & their drainage area
Locate the superficial inguinal ring
Reveal the course of great saphenous vein Explore
the fascia lata and opening contained in it Identify
the attachments of muscles of anterior facial
compartments of thigh along with their blood and
nerve supply
Explain the boundaries and contents of femoral
canal
identify the boundaries and contents of femoral
triangle
Knowledge:
Describe the boundaries, compartments, contents
and importance of femoral sheath
Describe in tabulated form the origin, insertion,
blood and nerve supply and actions of muscles of
anterior facial compartments of thigh
Analyze the clinical scenarios related with: Varicose
veins
Great saphenous vein cutdown
5 Medial fascial
Compartment of
Thigh
Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of
medial compartment of thigh of the cadaver after
performing dissection.
Knowledge:
Describe the origin, insertion, nerve supply and
actions of muscles of medial facial compartments of
thigh
Analyze the clinical scenario related with obturator nerve injury
35
6 The back of the
thigh
Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of back
of thigh of the cadaver after performing dissection.
Knowledge:
Describe the origin, insertion, nerve supply and
actions of muscles of posterior facial compartments
of thigh
Mark the deep seated structures on the surface of
region
Analyze the clinical scenario related with sciatic
7 Hip joint Gross
Anatomy
SG
D
Skill:
Demonstrate the articulation of hip joint
Knowledge:
Describe the articulation, type, capsule, ligaments,
synovial membrane, nerve supply, blood supply
and important relations of hip joint
Discuss the various movements of hip joint along
with muscles responsible for these movements
Discuss the importance of artery to the ligament of
the femoral head in Fractures of the Femoral Neck
Discuss the anatomical structures involved in
Dislocation of Hip Joint
Analyze the clinical scenarios related with hip joint stability and trendelenburg’s sign
8 Bones of leg Gross
Anatomy
SG
D
Skill:
Identify the patella and its landmarks Demonstrate
the anatomical position of tibia & fibula and
determine their side
Recognize important bony land marks on gross
inspection as well as on radiographs
Knowledge:
Discuss patellar dislocations & patellar fractures
Describe and identify the muscle & ligamentous
attachments on tibia & fibula
Identify the common sites of fractures of tibia and
fibula and correlate them with their clinical
presentation based on the knowledge of Anatomy
Discuss clinical importance of intraosseous
infusion of tibia in infants
9 Popliteal fossa Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of
popliteal fossa of the cadaver after performing
dissection.
Knowledge:
36
Enlist the structures forming various boundaries of
popliteal fossa
Enumerate the contents of popliteal fossa and
discuss their inter-relationships
Draw and label genicular anastomosis and
discuss its clinical significance
10 Fascial
compartments of
leg
Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of
fascial compartments of leg of the cadaver after
performing dissection
Knowledge:
Enumerate the contents of anterior, lateral and
posterior compartments of leg.
Describe origin, insertion and actions of muscles
contained within anterior, lateral and posterior
compartment of leg.
Explain blood and nerve supply of anterior, lateral
and posterior compartment of leg
Discuss the following clinical conditions related
with structures in the region of leg:
Anterior compartment of leg syndrome
Tenosynovitis & dislocation of peroneus longus &
brevis tendons
Gastrocnemius & soleus muscle tears
Ruptured tendocalcaneus
Rupture of plantaris tendon
Plantaris tendon & autografts
Deep vein thrombosis & long distance air travel
Describe the retinaculae of ankle with reference to
their attachments and structures passing
underneath them
Analyze the clinical scenarios related with
common peroneal and tibial nerve injuries
37
11 Knee joint Gross
Anatomy
SG
D
Skill:
Demonstrate the articulation of knee joint
Knowledge:
Describe the articulation, type, capsule, ligaments
(extra and intra articular), synovial membrane,
nerve supply, blood supply, important relations,
and movements related to the knee joint
Explain the mechanism of locking and unlocking of
the knee joint
Name the bursae related to knee joint and point
out those which communicate with the joint cavity
Analyze the clinical scenarios related with patellar
tendon reflex and various types of bursitis Discuss
the following:
Quadriceps femoris as knee joint stabilizer
Strength of knee joint
Knee injury and synovial membrane
Ligamentous injury of knee joint
Meniscal injury of knee joint
Pneumoarthrography
12 Proximal &
distal
Tibiofibular joints
Gross
Anatomy
SG
D
Knowledge:
Describe the articulation, type, capsule, ligaments,
nerve supply, blood supply, and movements
related to these joints
13 Ankle joint Gross
Anatomy
SG
D
Skill:
Demonstrate the articulation of ankle joint
Knowledge:
Describe the articulation, type, capsule, ligaments,
synovial membrane, nerve supply, blood supply,
movements and important relations of the joint
Differentiate between acute sprains of lateral ankle
and medial ankle
Describe the fracture dislocation of ankle joint
Discuss the sensory and motor loss associated with
tibial nerve entrapment in tarsal tunnel syndrome
Analyze the clinical scenario related with achilles
38
14 Articulated foot Gross
Anatomy
SG
D
Skill:
Identify the bones of foot
Demonstrate anatomical position and determine
their side of calcaneus and talus
Recognize important bony landmarks, muscular &
ligamentous attachments on calcaneus & talus
Knowledge:
Describe articulation among various bones of foot
Describe foot as a functional unit
Describe arches of foot with reference to bones of
arches, and mechanisms of arch support
Discuss mechanism of walking
Discuss the clinical problems associated with the
arches of foot 15 Intertarsal joints Gross
Anatomy
SG
D
Skill:
Identify articulation, type of joint,
important ligaments and movements at
these joints on an
16 Sole of foot Gross
Anatomy
SG
D
Skill:
Explore and identify the structural anatomy of six
layers of sole of foot of the cadaver after
performing dissection
Knowledge:
Describe the attachments and relations of plantar
aponeurosis
Describe in tabulated form the origin, insertion,
nerve supply and action of muscles of sole of foot
Describe arteries and nerves of sole of foot
17 The dorsum of foot Gross
Anatomy
SG
D
Knowledge:
Describe the origin, insertion, nerve supply and
action of extensor digitorum brevis
Describe arteries and nerves of dorsum of foot
18 Cutaneous
innervations of
lower limb
Gross
Anatomy
SG
D
Knowledge:
Describe the cutaneous nerve supply of lower limb
Draw & label cutaneous innervation of lower limb
Draw & label the dermatomes of lower limb
39
19 Blood supply of
lower limb
Gross
Anatomy
SG
D
Knowledge:
Describe blood supply of lower limb
Discuss the following:
Arterial palpation
Collateral circulation
Traumatic injury to femoral artery
Arterial occlusive disease of the leg
Saphnous cut down
20 Lymphatic drainage
of lower limb
Gross
Anatomy
SG
D
Knowledge:
Describe the lymphatic drainage of lower limb
21 Surface marking Gross
Anatomy
SG
D
Skill:
Mark the nerves and vessels of lower limb on the
surface of region with the help of important bony
HISTOLOGY
22 Respiratory system Histolog
y
IL Enlist the main divisions of respiratory passage
along with the structures constituting each?
Define respiratory and olfactory epithelium
Enumerate cells comprising respiratory & olfactory
epithelium. Describe their light microscopic
structure with the help of diagram
Describe the histological structure of the following
with the help of diagram:
Paranasal air sinuses
Nasopharynx
Larynx
Trachea
Lungs
Pleura
Differentiate various parts of bronchial tree on the
basis of lining epithelium, presence of cilia, glands,
cartilage, smooth muscles, and elastic fibers Analyze
clinical scenario regarding:
Immotile cilia syndrome
EMBRYOLOGY
40
23 Birth defects Embryo IL Enumerate types of birth abnormalities & define
each of them with at least one example Summarize
principles of teratology
Classify teratogens with associated human
malformations in tabulated form
Enlist numerical & structural chromosomal
abnormalities
Discuss the following numerical chromosomal
abnormalities:
Trisomy 21
Trisomy 18
Trisomy 13
Klinefelter syndrome
Turner syndrome
Discuss the following structural chromosomal
abnormalities:
Cri-du-chat syndrome
Angelman’s syndrome
Prader-willi syndrome
Miler-dieker syndrome
Define mosaicism & discuss its embryological basis
Discuss critical periods of prenatal human
development
Discuss invasive and noninvasive approaches for
assessing growth & development of fetus in utero
24 Development of
body cavities
Embryo IL Explain transformation of single intraembryonic
coelom into pericardial, pleural and peritoneal
cavities
Enlist development sources of diaphragm Describe
development of diaphragm
Discuss positional changes of diaphragm with
reference to age of fetus
Explain the innervation of diaphragm with
reference to its developmental sources
Analyze clinical scenarios regarding:
41
25 Development of
respiratory system
Embryo IL Describe the development of the following:
Larynx
Trachea
Bronchi
Lungs
Describe different stages of lung maturation Enlist
factors responsible for normal lung
maturation
Enlist the postnatal changes that occur in lungs
Analyze clinical scenarios regarding:
Various types of tracheoesophageal fistulas
Respiratory distress syndrome
26 Development of
skeletal system
Embryo IL Describe histogenesis of cartilage
Describe histogenesis of bone
Explain development of joints
Describe development of vertebral column
Define spina bifida. Enlist its different types. Give
embryological basis of bifid spine
alongwith methods of prenatal
assessment in this anomaly Explain development
of ribs and sternum with congenital defects
Discuss embryological basis and associated birth
defects of:
Klippel feil syndrome
Accessory ribs Fused
ribs Hemivertebra
Rachiscisis
Anomalies of sternum
42
27 Development of
muscular system
Embryo IL Describe development of skeletal musculature
Define lateral somitic frontier. Enlist the structures
whose borders are defined by lateral somitic
frontier.
Enumerate the muscles derived from primaxial and
abaxial domains
Summarize the innervation of axial skeletal
muscles
Enlist the developmental source of:
Head muscles
Limb muscles
Cardiac muscles
Smooth muscles
Discuss the following clinical anomalies:
Poland sequence
28 Development of
limbs
Embryo IL Describe the formation of limb buds
Define apical ectodermal ridge and discuss its role
in limb development including digits
Describe limb growth and development
Discuss rotation of limbs during development.
Describe the relationship between rotation of limbs
& cutaneous nerve supply of limbs Differentiate
between development of upper and lower limbs
Discuss development of limb musculature
Enumerate and describe the various types of limb
defects. Discuss their embryological basis
General Anatomy
29 Skin & fascia General
Anatomy
SG
D
Enumerate the components of integumentary
system.
Enlist the functions of integumentary system Enlist
the two main parts of skin. Enumerate its layers
with their general features.
Enumerate appendages of skin. Describe their
general features.
Define cleavage lines? Describe their clinical
importance.
30 Vertebral column General
Anatomy
SG
D
Describe the anatomy of vertebral column with
reference to:
Number of vertebra in different regions
Curvatures of vertebral column
Describe defects in the curvature of vertebral
43
31 Nervous system-II General
Anatomy
SG
D
Describe division of nervous system on gross
anatomical basis
Enumerate components of central and peripheral
nervous system. Describe their general features
Define autonomic nervous system (ANS). Enlist the
differences between autonomic and somatic
nervous system
Enlist the main divisions of ANS? Describe
differences of its two main divisions in tabulated
form.
Enumerate cranial parasympathetic ganglia.
Describe their general features
Define enteric nervous system. Describe its
general features.
List of Practical work:
Histology of Bronchial
Tree Histology of Lung -I
Histology of Lung -II
44
First Professional MBBS Examination
ANATOMY
Table of Specifications for Annual First Professional Examination: Theory
Time Allowed =03 hrs (Including MCQs)
Marks of theory paper =90
Internal assessment =10
Total marks =100
Pass Marks =50
Paper- 1
45 x MCQs (on separate sheet) (45 Marks) Time =50 min
Paper- 2
6x SAQs/SEQs (Recall) = 05 marks each
3 x SAQs/SEQs (Application) = 05 marks each (45 Marks) Time = 2 hours 10 minutes
S.No
Topic
NUMBER OF MCQs (45)
Recall:25
Application: 20
1 mark each
NUMBER OF SAQs/SEQs (09)
05 marks each
Recall Application
1. Embryology 08 01 01
2. Histology 07 01 -
3. General Anatomy 05 - -
4. Upper limb 09 1.5 01
5. Lower limb 09 1.5
6. Thorax 07 01 01
Total 45 (45 Marks) 06(30 Marks) 03(15 Marks)
09(45 Marks)
Viva 50 Marks Practical 40 Marks
Internal Assessment Calculation 20 Marks (10% of Exam)
Module I Module II Module III Sendup Total Written & VIVA
05 Marks 05 Marks 05 Marks 05 Marks 20 Marks 10+10 Marks
CBL/Assignments / Gross Sketch copy included in each modular assessment.
42
42
HISTOLOGY
Text Books Reference Books
Basic Histology
By Luiz carlos Junqeira (14th
Edition)
Medical Histology by Prof. Laiq
Hussain (6th
edition)
Di-fiore`s Atlas of Histology (12th
Edition) Histology
By Michel H. Ross (6th
Edition)
Contextual journal of Histology Vol-I (For
both MBBS and BDS)
By Prof. Dr. Nazreen Sharif
Contextual journal of Histology Vol-II
By Prof. Dr. Nazreen Sharif (for BDS only)