* wnt proteins bind to frizzled receptors and inhibit the degradation of -catenin
TRANSCRIPT
* Wnt proteins bind to frizzled receptors and inhibit the degradation of -catenin
Extracellular signal molecule
Receptor protein
Intracellular signaling proteins
Target proteins
Metabolic enzyme
Gene regulatory protein
Cytoskeletal protein
Extracelluar signal
molecules bind to specific receptors
Three classes of cell-surface receptors
oror
Gene transcription is activated by a rise in cAMP conc
Relay protein
Amplifier and transducer protein
Messenger protein
MAP-kinase serine/threonine phosphorylation pathway activated by
Ras
Raf
MEK
MAPK
Cytokine receptors activate the Jak-STAT signaling pathway
JAKsJAK1JAK2JAK3Tyk2
Signal transducers and activators of transcription
* Wnt proteins bind to frizzled receptors and inhibit the degradation of -catenin