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LLTTP P is a software company dedicated to improving workflow efficiency and productivity in the clinical laboratory

LLTTP P Products: Automate results verification, review, follow-up actions

and disposition for Hematology, Coagulation, Chemistry & Immunochemistry, and Urinalysis

Optimize by monitoring workflow in real-time and retrospectively

Provide real-time Quality Control compliance Allow you to expand your hematology services to

automate BALBAL and other fluid analyses

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What LLTTPP does

How LLTTPP worksHow the LLTTPP review-criteria optimization

process works

How LLTTPP reduces operating costs/improves profitability

What LLTTPP products are available products are available3

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LLTTPP ACHIEVERACHIEVER™™

LLTTPP OPTIMIZEROPTIMIZER™™

LLTTPP BALBAL/HEMATOLOGY/HEMATOLOGY™™

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LLTTPP QC SENTINELQC SENTINEL™™

LabLabThroughThroughPutPut ™™

GlobaLab Efficiency Products

LLTTPP MIDDLEWAREMIDDLEWARE™ ™ SYSTEM SYSTEM ConfigurationConfiguration

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LLTTPP GlobaLabGlobaLab ™ ™ Products Products

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LLTTPP HEMATOLOGYHEMATOLOGY™™

LLTTPP COAGULATIONCOAGULATION™™ LLTTPP CHEMISTRYCHEMISTRY™™ LLTTPP URINALYSISURINALYSIS™™



LLTTPP QC SENTINELQC SENTINEL™™

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LLTTPP ACHIEVERACHIEVER is a system that optimizes results processing in the laboratory and improves productivity

ACHIEVER MODULESACHIEVER MODULES

◼ SYSTEM SETUP and SECURITY

◼ INSTRUMENT MANAGER

◼ EVALUATOR

◼ PROCESSOR

◼ ENDSHIFT

◼ MONITOR

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ACHIEVER MODULE ACHIEVER MODULE Functionality◼ SYSTEM SETUP and SECURITY

Provides for Defining: access level heirarchy, user/password control, parameters, review rules, edit/display order, and Shift report content and distribution

◼ INSTRUMENT MANAGERControls data transmission: receives data from analyzers and

LIS, transmits to analyzers and LIS; monitors connectivity

◼ EVALUATOR Evaluates results by autoverification of User Rules: assigns

samples to worklists and locates them for tech data entry screens, provides disposition of results

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ACHIEVER MODULE ACHIEVER MODULE Functionality PROCESSOR

Provides for all operations: label printing, data entry/modification, Supervisory review/approval, tracks current status and audit trail of results, and provides for archive and retrieval

ENDSHIFTCloses Instrument Manager at defined end of shift times;

creates, distributes and saves End of Shift Reports

MONITORChecks Instrument Manager and Evaluator continually, in the

background, for proper functioning of data entry/modification

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WHAT LLTTPP ACHIEVERACHIEVER DOES LLTTPP ACHIEVERACHIEVER is a complete results

processing system.◼ Auto-verifies analyzer results◼ Issues follow-up worklists along with procedures ◼ Provides data entry screens for necessary results

changesOn-screen diffpad for microscopic observation entry

◼ Determines final disposition◼ Transmits results to the host computer system for

release◼ Stores every state of every specimen record in a

database; maintains audit trail◼ Self-monitors and diagnoses system operations◼ Produces activity and productivity reports

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Functions User-definable setup of:

Review Rules Instrument and Lab-defined parameters to receive Parameters to be displayed/edited by techs, including

display order Parameters to be transmitted to LIS User names/passwords Access levels to system functions Shift Report contents and E-mail recipients

Features User defines which parameter value fields can be

edited by tech, and under which circumstances Parameter field background colors are user-

definable for clarity10

SYSTEM SETUP & SECURITY MODULESYSTEM SETUP & SECURITY MODULE


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LLTTPP SYSTEM SETUP SCREENSSYSTEM SETUP SCREENS

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LLTTPP SYSTEM SETUP REVIEW CRITERIA REPORTSYSTEM SETUP REVIEW CRITERIA REPORT

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Functions Receives data from analyzers and LIS Transmits data to analyzers and LIS

Features Analyzer/Instrument Manager connectivity

diagnostics Host/Instrument Manager connectivity

diagnostics Issue connectivity alerts audibly, via E-mail and via text

messaging

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INSTRUMENT MANAGER MODULEINSTRUMENT MANAGER MODULE


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LLTTPP INSTRUMENT MANAGER SCREENINSTRUMENT MANAGER SCREEN

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EVALUATOR Features: Follow-up procedure worklists are created based

on User criteria Special follow-up options include automatic

replacement of instrument parameter values by values obtained on the instrument by other means; e.g. WIC/WOC or analyte dilution results

Audit trail maintenance: Database archival of up to 1,000,000 specimen records Every state of every record is stored in a database All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made– WHAT Method used to make the change

Final disposition state for each specimen record is recorded

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EVALUATOR MODULEEVALUATOR MODULE

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LLTTPP EVALUATOR MODULE SCREENEVALUATOR MODULE SCREEN

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PROCESSOR Features: Open architecture supports simultaneous

analysis of any combination of:Multiple SpeciesAnalyzer manufacturers/models Body fluid types

Analyzes specimen results on-line in real-time, using your verification criteria. Special verification options include:

– Activation/de-activation of individual rules within a set– Advanced delta-check techniques – Color coding for: Rerun, Diff needed, Spun Hct– Tech ID, data entry, results and workstation tracked

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PROCESSOR MODULEPROCESSOR MODULE

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ENDSHIFT MODULEENDSHIFT MODULE

Endshift Features The Endshift process is entirely automatic

Stops Instrument Manager and Evaluator automatically

Restarts Instrument Manager and Evaluator automatically when Endshift process is completed

Endshift Report contents and recipients are User definable

Endshift will not occur if LLTTPP detects that specimens are still being processed

Endshift times can vary by day and shift Multiple Endshifts per day can be programmed Number of Endshift retries and retry intervals are

user definable


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MONITOR Features: Monitors Evaluator and Instrument Manager for

functional compliance Starts automatically at beginning of shift and runs

in the background Restarts application(s) if fault is detected Maintains an all inclusive event Log

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MONITOR MODULEMONITOR MODULE

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LLTTPP MONITOR MODULE SCREEN MONITOR MODULE SCREEN

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WHAT LLTTPP OPTIMIZER OPTIMIZER DOES LLTTPP OPTIMIZER OPTIMIZER ™ helps you optimize

specimen results throughput in the laboratory Uses your results-verification criteria to measure

the overall specimen-result review rate in the laboratory

Determines the frequency of follow-ups based on each criterion, and the frequency of each follow-up procedure; eg. analyzer reruns or manual differentials

Allows readjustment of criteria and re-analyzes the results to optimize criteria and improve throughput

Provides database query capability

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WHAT LLTTP P OPTIMIZER OPTIMIZER DOESOPTIMIZER Features

LLTTP P OPTIMIZEROPTIMIZER™ provides review rates: For all specimens combined Based on individual review criterion Based on instrument, for multiple-instrument

systems Based on instrument model, for labs using more

than one analyzer model (open architecture) Based on body fluid type, for labs running whole

blood samples and other body fluids Based on species, for veterinary labs

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Functions Queries either the live or archival database for

performance parameters Productivity summary by analyzer or by operator # of specimens analyzed over time interval per species,

analyzer, tech, body fluid type, etc. # of specimens work-listed per rule, per species, per

analyzer, per body fluid type # of follow-up actions per rule, per species, per analyzer, per

body fluid type

Features Analysis of archived results based on rules applied

live Analysis of archived results using modified review

rules23

LLTTPP OPTIMIZER OPTIMIZER QUERY MODULEQUERY MODULE


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WHAT LLTTPP ACHIEVERACHIEVER/HEMATOLOGY/HEMATOLOGY™ ™ DOES LLTTPP ACHIEVERACHIEVER/HEMATOLOGY /HEMATOLOGY is a complete

results processing system. Auto-verifies hematology analyzer results Issues follow-up worklists along with procedures Provides data entry screens for necessary results

changesOn-screen diffpad

Determines final disposition Transmits results to the host computer system for

release Stores every state of every specimen record in a

database

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LLTTPP ACHIEVERACHIEVER/HEMATOLOGY/HEMATOLOGY™™

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HOW the LLTTPP review-criteria optimization process works

SETUP REVIEW CRITERIA & SECURITY ENTER (AND EDIT) REVIEW CRITERIA

REVIEW-CRITERIA BATCH SCREEN REVIEW-CRITERION EDITOR

Review specimen record data Examine results of specimen record

review Edit review criteria and re-analyze data

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Functions User-definable setup of:

Review Rules Instrument and Lab-defined parameters to receive Parameters to be displayed/edited by techs, including

display order Parameters to be transmitted to LIS User names/passwords Access levels to system functions Shift Report contents and E-mail recipients

Features User defines which parameter value fields can be

edited by tech, and under which circumstances Parameter field background colors are user-

definable for clarity26

SYSTEM SETUP & SECURITY MODULESYSTEM SETUP & SECURITY MODULE


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LLTTPP HEMATOLOGY HEMATOLOGY SYSTEM SETUP SCREENSSYSTEM SETUP SCREENS

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LLTTPP HEMATOLOGY HEMATOLOGY SYSTEM SETUP REVIEW CRITERIA REPORTSYSTEM SETUP REVIEW CRITERIA REPORT

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LLTTPP HEMATOLOGY HEMATOLOGY REVIEW CRITERION SETUP SCREENREVIEW CRITERION SETUP SCREEN

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Review criteria are grouped. A set (“batch”) of criteria is entered for each combination of instrument type/body fluid type/species (see slide 12)

Multiple sets can be active simultaneously, but only one set at a time can be active for each combination of instrument type/body fluid type/species

Sets and individual criteria can be de-activated

Specimens not matching any set are flagged Sets can be printed

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ENTER/EDIT REVIEW CRITERIAENTER/EDIT REVIEW CRITERIA


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Review criteria include Limits

Parameter values Products of 2 parameter values Ratios of 2 parameter values Sums of 2 parameter values Differences of 2 parameter values % differences of 2 parameter values

Morphology Flags Presence Severity

System Operational Alerts Presence Severity

(CONTINUED ON NEXT SLIDE)

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Review criteria include: Demographics

Age Gender

Blanked resultsDelta Checks (Apply to any combination of parameters listed

above under limits) Difference Absolute difference % difference Absolute % difference Rate of delta for any of the above, by:

– Day, Week or Month

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INSTRUMENT TYPE

SPECIES

SPECIMEN TYPE

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LLTTPP HEMATOLOGY HEMATOLOGY REVIEW CRITERIA BATCH SCREENREVIEW CRITERIA BATCH SCREEN

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FORMULAS

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LLTTPP HEMATOLOGY REVIEW CRITERION EDITOR SCREENHEMATOLOGY REVIEW CRITERION EDITOR SCREEN

CRITERIONACTION

PARAMETER THAT IS RE-ANALYZED AFFECTED PARAMETER(S)

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PARAMETER LIST

35

LLTTPP HEMATOLOGY HEMATOLOGY REVIEW CRITERION EDITOR SCREENREVIEW CRITERION EDITOR SCREEN

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MORPHOLOGY FLAG LIST

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SYSTEM OPERATIONAL ALERTS

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LLTTPP HEMATOLOGY HEMATOLOGY REVIEW CRITERION EDITOR SCREENREVIEW CRITERION EDITOR SCREEN

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OPERATORS

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RELATIONAL OPERATORS

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LIST OF ACTIONS

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EVALUATOR Features Follow-up procedure worklists are created based

on your criteria Special follow-up options include automatic

replacement of instrument parameter values by values obtained on the instrument by other means; e.g. WIC/WOC

Audit trail maintenance: Database archival of up to 500,000 specimen records Every state of every record is stored in a database All changes made to results are recorded/audit trailed

– WHO, WHEN and WHY any change was made– WHAT Method used to make the change


41


EVALUATOR MODULEEVALUATOR MODULE

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LLTTPP HEMATOLOGY HEMATOLOGY EVALUATOR MODULE SCREENEVALUATOR MODULE SCREEN

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Functions Provides for all operations: label printing, data

entry/modification, Supervisory review/approval, tracks current status and audit trail of results, and provides for archive and retrieval

Features Auto-verifies analyzer results Issues follow-up worklists along with procedures Provides data entry screens for necessary results

changesOn-screen diffpad or microscopic observation entry

Determines final disposition Stores every state of every specimen record in a

database

43



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PROCESSOR Features Open architecture supports any combination of:

Analyzer manufacturers/models Body fluid types Species


– Activation/de-activation of individual rules within a set– Advanced delta-check techniques – Color coding for: Rerun, Diff needed, Spun Hct– Tech ID, data entry, results and workstation tracked

44



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LLTTPP HEMATOLOGY HEMATOLOGY PROCESSOR SCREENPROCESSOR SCREEN

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MORE SPECIMENINFORMATION

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LLTTPP HEMATOLOGY HEMATOLOGY REVIEW SPECIMEN RECORD DATA SCREENREVIEW SPECIMEN RECORD DATA SCREEN

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REVIEW RATE BY ACTION

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LLTTPP HEMATOLOGY HEMATOLOGY REVIEW SPECIMEN RECORD DATA SCREENREVIEW SPECIMEN RECORD DATA SCREEN

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LLTTPP HEMATOLOGY HEMATOLOGY PROCESSOR SCREENPROCESSOR SCREEN

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50



FunctionsCloses Instrument Manager and

Evaluator at predetermined times during the day

Creates shift reports that include Overall workshift output Technologist productivity Analyzer outputs by table and graphical

display Review rules analysis

Saves reports on system server and emails reports to designated addresses

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51



Features Endshift times can vary by day and shift Multiple Endshifts per day can be programmed Report contents and recipients are user definable The Endshift process is entirely automatic

Stops Instrument Manager and Evaluator automatically

Restarts Instrument Manager and Evaluator automatically when Endshift process is completed

Endshift will not occur if LLTTPP detects that specimens are still being processed

Number of Endshift retries and retry intervals are user definable

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LLTTPP ENDSHIFT REPORTED RESULTSENDSHIFT REPORTED RESULTS

YOUR LAB ADDRESS, ETC

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LLTTPP ENDSHIFT PENDING RESULTSENDSHIFT PENDING RESULTS


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LLTTPP ENDSHIFT CUMULATIVE INSTRUMENT REPORTENDSHIFT CUMULATIVE INSTRUMENT REPORT


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LLTTPP ENDSHIFT INSTRUMENT MANAGER REPORTENDSHIFT INSTRUMENT MANAGER REPORT


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WHAT LLTTPP OPTIMIZER OPTIMIZER DOES LLTTPP OPTIMIZEROPTIMIZER/HEMATOLOGY/HEMATOLOGYTM TM is

software that helps you optimize specimen results throughput in the laboratory It uses your results-verification criteria to

measure the overall specimen-result review rate in the laboratory

It determines the frequency of follow-ups based on each criterion, and the frequency of each follow-up procedure such as analyzer reruns or manual differentials

It allows you to adjust the criteria and re-analyze the results so that you can optimize your criteria and improve throughput

59

LLTTPP OPTIMIZER/OPTIMIZER/HEMATOLOGYHEMATOLOGY™™

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WHAT LLTTPP OPTIMIZER OPTIMIZER DOESFeatures

LLTTPP OPTIMIZEROPTIMIZER/HEMATOLOGY/HEMATOLOGYTM TM

provides review rates: For all specimens combined Based on individual review criterion Based on instrument, for multiple-instrument

systems Based on instrument model, for labs using

more than one analyzer model (open architecture)

Based on body fluid type, for labs running whole blood samples and other body fluids

Based on species, for veterinary labs

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LLTTPP OPTIMIZEROPTIMIZER/HEMATOLOGY/HEMATOLOGY™™

©

Functions Queries either the live or archival database for

performance parameters Productivity summary by analyzer or by operator # of specimens analyzed over time interval per species,

analyzer, tech, body fluid type, etc. # of specimens work-listed per rule, per species, per

analyzer, per body fluid type # of follow-up actions per rule, per species, per analyzer,

per body fluid type

Features Analysis of archived results based on rules applied

live Analysis of archived results using modified review

rules61

LLTTPP OPTIMIZER OPTIMIZER QUERY MODULEQUERY MODULE

LLTTPP OPTIMIZEROPTIMIZER/HEMATOLOGY/HEMATOLOGY™™

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LLTTPP OPTIMIZER OPTIMIZER QUERY CATEGORIES SCREENQUERY CATEGORIES SCREEN

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LLTTPP OPTIMIZER OPTIMIZER QUERY RESULTS SCREENQUERY RESULTS SCREEN

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HOW LLTTPP REDUCES OPERATING COSTS

Redeployment of skilled results-review staff

Eliminates erroneous specimen record handling decisions

Optimizes review criteria/follow-up processes

Provides audit trail

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Hematology Products


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LLTTPP QCQC SENTINELSENTINEL/HEMATOLOGY/HEMATOLOGY™™

LLTTPP MOUSE MOUSE BALBAL™™ LLTTPP RAT RAT BALBAL™™ LLTTPP GUINEA PIG GUINEA PIG BALBAL™™

LLTTPP MONKEY MONKEY BALBAL™™

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WHAT LLTTPP BAL/HEMATOLOGY DOES LLTTPP BAL/HEMATOLOGY is software that

automates BAL fluid specimen analyses on ADVIA 120/2120 No sample preparation Reduces sample analysis time to approximately 1

minute/sample Reports results in XL spreadsheet format

WBC #,%Neuts #,%Eos #,% Mononuclear cells

Does NOT affect or alter ADVIA 120/2120 software

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WHAT LLTTPP BAL/HEMATOLOGY DOES Product Features

WBC count @20 cells/µL Differential @50 cells/µL No RBC interference in WBC analysis Species supported

Mouse allergic model and smoke inhalation modelRat allergic model and smoke inhalation modelCynomolgus monkey allergic modelGuinea pig allergic model

Does NOT affect or alter ADVIA 120/2120 software

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Mouse

Whole Blood

Mouse BAL

Eos Model

Whole Blood Archetype

Mouse BAL

Eos Model

BAL Archetype

WBC

(/uL)

%N %E %L %MNC

MAN 103 7.0 55.7 6.7 30.7

WB ARCH

180 12.6 38.7 32.8

15.9

BAL

ARCH100 0.0 50.0 10.

040.0

Comparative Results

Eos

Lymphs

MNCLipid

MN

PMN

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LLTTPP BALBAL/HEMATOLO/HEMATOLO

GYGY™™

LLTTPP MOUSE MOUSE BALBAL™™

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Mouse BAL

EOS + Neuts Model


Mouse BAL

Eos + Neuts Model

BAL Archetype

WBC

(/uL)

%N %E %L %MNC

MAN No Manual

31 8 3 58

WB ARCH

NA 16.2 13.8 25.2 43.9

BAL

ARCHNA 37.8 8.9 13.3 40.0

Comparative Results

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GYGY™™

Mouse


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Mouse BAL

Smoke Inhalation

Negative Control


Mouse BAL

Smoke Inhalation

Negative Control

BAL Archetype

WBC

(/uL)

%N %MNC

MAN 12.5 0.5 99.5

WB

ARCH

70 28.3 47.2

BAL ARCH

20 0 100

Comparative Results

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GYGY™™

Mouse


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Mouse BAL

Smoke Inhalation

Positive CTRL


Mouse BAL

Smoke Inhalation

Positive CTRL

BAL Archetype

WBC

(/uL)

%N %MNC

MAN 142.5 43.5 56.5

WB

ARCH

460 50.9 32.0

BAL

ARCH

120 50 50

Comparative Results

Debris

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GYGY™™

Mouse


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Mouse BAL

Smoke Inhalation

Drug-Treated


Mouse BAL

Smoke Inhalation

Drug-Treated

BAL Archetype

WBC

(/uL)

%N %MNC

MAN 70 28 72

WB ARCH

190 28.5 47.8

BAL

ARCH

58 31 69

Comparative Results

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GYGY™™

Mouse


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Rat

Whole Blood

BAL

Allergic Model

Negative Control


BAL

Allergic Model

Negative Control

BAL Archetype

WBC

(/uL)

%N %E %MNC

MAN 133 8 5 87

WB

ARCH

140 36.6 3.6 59.9

BAL ARCH

130 13.8 1.5 84.6

Comparative Results

MN

PMN

MNC

LymphsNeuts

Eos

Debris

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GYGY™™

LLTTPP RAT RAT BALBAL™™

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Rat

Rat BAL

Allergic Model

Positive Control


Rat BAL

Allergic Model

Positive Control

BAL Archetype

WBC

(/uL)

%N %E %MNC

MAN 450 34 29 37

WB

ARCH

460 40.7 26.9 30.8

BAL ARCH

421 45.6 21.1 33.3

Comparative Results

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GYGY™™


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Rat BAL

Allergic Model

Drug-Treated


Rat BAL

Allergic Model

Drug-Treated

BAL Archetype

WBC

(/uL)

%N %E %MNC

MAN 623 25 65 10

WB

ARCH

620 14.3 70.0 15.5

BAL ARCH

576 24.8 59.5 15.6

Comparative Results

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GYGY™™

Rat


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CynomolgusMonkeyWhole Blood

Cyno Monkey BAL

Allergic Model

Negative Control


Cyno Monkey

Allergic Model

Negative Control

BAL Archetype

WBC

(/uL)

%N %E %MNC

MAN 100 1 1 98

WB ARCH

190 39.7 1.3 59

BAL ARCH

92 7.5 6 86.5

Comparative Results

MN PMN

Debris

MNC

Lymphs

Neuts

Eos

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GYGY™™


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Cyno Monkey BAL

Allergic Model

Positive Control


Cyno Monkey BAL

Allergic Model

Positive Control

BAL Archetype

WBC

(/uL)

%N %E %MNC

MAN 346 7.3 49.0 43.7

WB

ARCH

440 52.0 12.0 36.0

BAL ARCH

342 4.5 39.7 55.7

Comparative Results

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GYGY™™

CynomolgusMonkey


©

Guinea Pig

Whole Blood

Guinea Pig BAL Allergic Model

Positive Control


Guinea Pig BAL Allergic Model

Positive Control

BAL Archetype

WBC

(/uL)

%Neut %Eos %MNC

Man 2900 36.5 45.5 18.0

WB

Arch

2950 46.4 29.4 24.2

BAL Arch

2950 31.0 45.5 23.5

Comparative Results

Debris

Eos

NMC

Neuts

78Debris


GYGY™™

LLTTPP GUINEA PIG GUINEA PIG BALBAL™™

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HOW LLTTPP REDUCES OPERATING COSTS

Automate time intensive manual process Provide standardized objective criteria Reduces specimen analysis time Allows redeployment of skilled staff

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LLTTPP ACHIEVERACHIEVER/COAGULATION/COAGULATION™™

LLTTPP OPTIMIZEROPTIMIZER/COAGULATION/COAGULATION™™

Coagulation Products

LLTTPP COAGULATIONCOAGULATION™™

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LLTTPP QCQC SENTINELSENTINEL/COAGULATION/COAGULATION™™

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WHAT LLTTPP ACHIEVERACHIEVER DOES LLTTPP ACHIEVERACHIEVER /COAGULATION /COAGULATION is a

complete results processing system. Auto-verifies coagulation analyzer results Issues follow-up worklists along with procedures Provides data entry screens for necessary results

changes Determines final disposition Transmits results to the host computer system for


database

81


©

WHAT LLTTPP ACHIEVERACHIEVER DOESFeatures

Open architecture supports any combination of:Analyzer manufacturers/models Body fluid types Species


– Activation/de-activation of individual rules within a set– Advanced delta-check techniques – Rerun-only criteria

82


©

WHAT LLTTPP ACHIEVERACHIEVER DOES Features

Follow-up procedure worklists are created based on your criteria


– WHO, WHEN and WHY any change was made

– WHAT Method used to make the change


83


©

WHAT LLTTPP OPTIMIZEROPTIMIZER DOES LLTTPP OPTIMIZEROPTIMIZER /COAGULATION /COAGULATION ™ is

software that helps you optimize specimen results throughput in the laboratory It uses your coagulation results-verification

criteria to measure the overall specimen-result review rate in the laboratory

It determines the frequency of follow-ups based on each criterion, and the frequency of each follow-up procedure such as analyzer reruns or prolonged clotting times


84

LLTTPP OPTIMIZER/OPTIMIZER/COAGULATIONCOAGULATION™™

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WHAT LLTTPP OPTIMIZEROPTIMIZER DOESFeatures

LTP OPTIMIZEROPTIMIZER /COAGULATION /COAGULATION ™ provides review rates:

For all specimens combined Based on individual review criterion Based on instrument, for multiple-instrument





85

LLTTPP OPTIMIZEROPTIMIZER/COAGULATION/COAGULATION™™

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LLTTPP ACHIEVERACHIEVER/CHEMISTRY/CHEMISTRY™™

LLTTPP OPTIMIZEROPTIMIZER/CHEMISTRY/CHEMISTRY™™

Chemistry Products

LLTTPP CHEMISTRYCHEMISTRY™™

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LLTTPP QCQC SENTINELSENTINEL/CHEMISTRY/CHEMISTRY™™

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WHAT LLTTPP ACHIEVERACHIEVER DOES LLTTPP ACHIEVERACHIEVER/CHEMISTRY /CHEMISTRY is a complete

results processing system. Auto-verifies chemistry analyzer results Issues follow-up worklists along with procedures Provides data entry screens for necessary results

changes Determines final disposition Transmits results to the host computer system for


database

87


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WHAT LLTTPP OPTIMIZEROPTIMIZER DOES LLTTPP OPTIMIZEROPTIMIZER/CHEMISTRY /CHEMISTRY ™ is software

that helps you optimize specimen results throughput in the laboratory It uses your chemistry results-verification criteria

to measure the overall specimen-result review rate in the laboratory

It determines the frequency of follow-ups based on each criterion, and the frequency of each follow-up procedure such as analyzer reruns, below detection limit or dilutions needed.


90

LLTTPP OPTIMIZER/OPTIMIZER/CHEMISTRYCHEMISTRY™™

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WHAT LLTTPP OPTIMIZER OPTIMIZER DOESFeatures

LLTTPP OPTIMIZER OPTIMIZER /CHEMISTRY /CHEMISTRY ™ provides review rates:

For all specimens and parameters combined Based on your individual review criterion Based on instrument, for multiple-instrument





91

LLTTPP OPTIMIZEROPTIMIZER/CHEMISTRY/CHEMISTRY™™

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LLTTPP ACHIEVERACHIEVER/URINALYSIS/URINALYSIS™™

LLTTPP OPTIMIZEROPTIMIZER/URINALYSIS/URINALYSIS™™

Urinalysis Products

LLTTPP URINALYSISURINALYSIS™™

92

LLTTPP QCQC SENTINELSENTINEL/URINALYSIS/URINALYSIS™™

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WHAT LLTTPP ACHIEVERACHIEVER DOES LLTTPP ACHIEVERACHIEVER/URINALYSIS /URINALYSIS is a complete

results processing system. Auto-verifies urinalysis analyzer results Issues follow-up worklists along with procedures Provides data entry screens for necessary results

changesOn-screen microscopic observation data entry pad

Determines final disposition Transmits results to the host computer system for


database93


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95


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WHAT LLTTPP OPTIMIZEROPTIMIZER DOES LLTTP P OPTIMIZER/OPTIMIZER/URINALYSISURINALYSIS™ ™ is software

that helps you optimize specimen results throughput in the laboratory It uses your urinalysis results-verification criteria

to measure the overall specimen-result review rate in the laboratory

It determines the frequency of follow-ups based on each criterion, and the frequency of each follow-up procedure such as analyzer reruns or microscopic element types (eg. crystals)


96

LLTTPP OPTIMIZER/OPTIMIZER/URINALYSISURINALYSIS™™

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WHAT LLTTP P OPTIMIZEROPTIMIZER DOES Features

provides review rates: For all specimens combined Based on your individual review criterion Based on instrument, for multiple-instrument





97

LLTTPP OPTIMIZEROPTIMIZER/URINALYSIS/URINALYSIS™™

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LabLabThroughThroughPutPut ™™ Products Products

98



LLTTPP QCQC SENTINELSENTINEL™™

Quality Control Module

QC SENTINELQC SENTINEL MODULEMODULE

IS PRESENTLY UNDER IS PRESENTLY UNDER DEVELOPMENTDEVELOPMENT

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99

WITHOUT LLTTPP MIDDLEWAREMIDDLEWARE

General LIS ConfigurationGeneral LIS Configuration

An LIS LIS has multiple connections multiple connections and interfaces, in multiple categoriesAnalyzer – LIS

A different interface for each analyzer brand

Numerous Data Entry WorkstationsPrinters

©

MainServer

BackupServer

SLIDES SLIDES SLIDES SLIDES

A4

BC PRT

PRT

SLIDES DIFFS DIFFS DIFFSDIFFS DIFFS DIFFS DIFFS DIFFS

A1

A2

A3

A5

A6

CD4

CD3

A7

CD2

A8

CD1

A14

A9

A10

A11

A12

A13

SupWS3

SupWS2

SupWS1

ANTRIM

External Storage

SLIDES = slide-making workstations

DIFFS = Diff-reader workstations

PRT = Printer

BC PRT = Barcode printer

SUP WS1-3 = Supervisor workstations

InstMgr12 = Instrument Manager workstation

External Storage = Terabyte drive

A1-A14 = ADVIA 120 Analyzers

CD1-CD4 = CellDyn 3500 Analyzers

Notes:

1. Server-to-Server connection by dedicated NICs.

2. InstMgr-to-Analyzer and InstMgr-to-ANTRIM connections via serial ports.

3. Analyzer-to-ANTRIM failsafe direct serial port connections not shown.

4. Circled numbers are hub connection #s

General LIS Configuration

1-6 8-15

©

101

WITH WITH LLTTPP MIDDLEWAREMIDDLEWARE

LLTTPP MIDDLEWAREMIDDLEWARE™ ™ SYSTEM SYSTEM ConfigurationConfiguration

The LIS LIS has only a single connection single connection to LLTTPP Middleware Middleware

LLTTPP Middleware Middleware is responsible for interfacing to the various categories of devices

LLTTPP Middleware Middleware unburdens the LIS LIS of interfacing with multiple laboratory devices, each with its own interface specification

Bidirectional LLTTPP Middleware – Middleware – LIS LIS interfaces follow standards such as ASTM1381/1395 or HL7

©

MainServer

BackupServer

SLIDES SLIDES SLIDES SLIDES

A4

BC PRT

PRT

SLIDES DIFFS DIFFS DIFFSDIFFS DIFFS DIFFS DIFFS DIFFS

A1

A2

A3

A5

A6

CD4

CD3

A7

CD2

A8

CD1

A14

A9

A10

A11

A12

A13

LLTTPPInstMgr

SupWS3

SupWS2

SupWS1

ANTRIM

External Storage

SLIDES = slide-making workstations

DIFFS = Diff-reader workstations

PRT = Printer

BC PRT = Barcode printer

SUP WS1-3 = Supervisor workstations

InstMgr12 = Instrument Manager workstation

External Storage = Terabyte drive

A1-A14 = ADVIA 120 Analyzers

CD1-CD4 = CellDyn 3500 Analyzers

Notes:

1. Server-to-Server connection by dedicated NICs.

2. InstMgr-to-Analyzer and InstMgr-to-ANTRIM connections via serial ports.

3. Analyzer-to-ANTRIM failsafe direct serial port connections not shown.

4. Circled numbers are hub connection #s

DSL

Hub

1-67

8-15

16-1920

21 22

LLTTPP Middleware System Configuration

©

103

LLTTPP System Backup System Backup

LLTTPP MIDDLEWAREMIDDLEWARE™ ™ SYSTEMSYSTEM

LLTTPP MIDDLEWAREMIDDLEWARE automatically copies the system environment, including applications and DB, to External Media daily

LLTTPP MIDDLEWARE MIDDLEWARE also continually replicates the environment to a Backup Server

The LLTTPP Backup Server automatically takes over if the Main Server fails

©

104

LLTTPP MIDDLEWAREMIDDLEWARE™ ™ SYSTEMSYSTEM

LLTTPP TECHNICAL SUPPORT Available whenever the laboratory is in

operation Lab personnel can call a telephone number

and speak directly with support staff Support staff have remote access to the

middleware system which enables them to quickly diagnose a problem and to make any necessary changes

LLTTPP System Technical Support System Technical Support

©

Thank YouThank You

for your attention.for your attention.

105

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