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  • YOUR CHALLENGES OUR SOLUTIONS...Big oste oph y ,d fn aro w j tspa ce,s v rcl d def init d orm yoh bo. OAR SI Gr ad e 1 Jo int Sp ac eN ar ow ing (0 -3) 3 0 Scle ro sis (0- 3) 2 0 Oste
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YOUR CHALLENGES The knee joint is not only the largest joint in the body but also a very complex structure. Extracting the relevant information can be tedious and time consuming. Even a minimal subjectivity can lead to distractions in the assessment of diseases. Consistent reporting is the key when making decisions that may affect patients quality of life. OUR SOLUTIONS Physicians assisted with KOALA agree 23% more between each other and show reduced rate at which healthy patients are mistakenly diagnosed with osteoarthritis.* KOALA allows to monitor disease progression treatment effciency in an objective and standardized matter. KOALA enables objective and consistent reporting allowing effective patient communication and treatment. A novel way of assessing knee osteoarthritis with the power of AI WHAT EXPERTS SAY “Exact diagnosis and reproducible follow-up exams of osteoarthritis is the basis for a pre- ventive and successful osteoarthritis therapy. Soſtware-based methods can assist the physician in the therapy management and adjustment process.” Michael Gruber, MD Radiologist, MSK Radiology “What the computer recognizes and describes, I do not have to. This reduces the amount of work to make a diagnosis, and the findings become more accurate. An objective value is given which can be used both for monitoring and forecasting the progress. We offer our patients something that others don’t have.” Stefan Nehrer, MD Orthopedic Surgery, Regenerative Medicine *measured by scoring orthopedic surgeons with and without KOALA assistance against a large longitudinal study based on US data. marked and FDA 510k pending.

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Page 1: YOUR CHALLENGES OUR SOLUTIONS...Big oste oph y ,d fn aro w j tspa ce,s v rcl d def init d orm yoh bo. OAR SI Gr ad e 1 Jo int Sp ac eN ar ow ing (0 -3) 3 0 Scle ro sis (0- 3) 2 0 Oste

YOUR CHALLENGES

The knee joint is not only the largest joint in the body but also a very complex structure. Extracting the relevant information can be tedious and time consuming. Even a minimal subjectivity can lead to distractions in the assessment of diseases.

Consistent reporting is the key when making decisions that may affect patients quality of life.

OUR SOLUTIONS

Physicians assisted with KOALA agree 23% more between each other and show reduced rate at which healthy patients are mistakenly diagnosed with osteoarthritis.*

KOALA allows to monitor disease progression treatment effciency in an objective and standardized matter.

KOALA enables objective and consistent reporting allowing effective patient communication and treatment.

A novel way of assessing knee osteoarthritis with the power of AI

WHAT EXPERTS SAY

“Exact diagnosis and reproducible follow-up exams of osteoarthritis is the basis for a pre-ventive and successful osteoarthritis therapy.

Software-based methods can assist the physician in the therapy management and adjustment

process.”

Michael Gruber, MD Radiologist, MSK Radiology

“What the computer recognizes and describes, I do not have to. This reduces the amount of work

to make a diagnosis, and the findings become more accurate. An objective value is given which can be used both for monitoring and forecasting

the progress. We offer our patients something that others don’t have.”

Stefan Nehrer, MD Orthopedic Surgery, Regenerative Medicine

*measured by scoring orthopedic surgeons with and without KOALA assistance against a large longitudinal study based on US data.

marked and FDA 510k pending.

Page 2: YOUR CHALLENGES OUR SOLUTIONS...Big oste oph y ,d fn aro w j tspa ce,s v rcl d def init d orm yoh bo. OAR SI Gr ad e 1 Jo int Sp ac eN ar ow ing (0 -3) 3 0 Scle ro sis (0- 3) 2 0 Oste

© 2018 IB Lab GmbH | [email protected] | www.ImageBiopsy.ai

KOALA - ZERO WORKFLOW CHANGES

POWERED BY ARTIFICIAL INTELLIGENCEFully-automated image processing AI software intended to support medical professionals. Precisely, in the standardized measurement of joint space narrowing, as well as radiographic features of osteoarthritis.

INTRODUCING KOALA KNEE OSTEOARTHRITIS LABELING ASSISTANT

Images are forwarded from PACS to KOALA, and annotations are attached to the original study. The results can be viewed in any DICOM viewer. The report is available in a black PDF/SC printable PDF as well.

PACSX-RAY

On premise server OR HIPAA-Compilant Cloud

KOALA

YOUR BENEFITS AT A GLANCE ✓ Consistent Reading:

Results are displayed immediately. Consistent reports summarize findings.

✓ Clinical Importance: Combining standartization, automatization and digitaliziation for more consistent results and better patient outcome.

✓ Flexible Integration: Further automation of your reporting work-flows possible by our structured reports.

✓ Better Reporting: Reading results automatically summarized as PDF report for referring physicians.

23% INCREASE

Physicians agreement rate

to gold-standard [%]

RESULTS AT A GLANCE93%

ACCURACY

Detecting joint space narrowing

92%PRECISION

Detecting Osteoarthritis

Soware Supported Assessment of Osteoarthritis Based on Kellgren & Lawrence | OARSI

Patient Name AnonymizedPatient ID 0Date of Birth --Accession #Date of Capture 2016-07-29

Kellgren & Lawrence (KL) Grade

0KL-Grade

(0-4) 4No signs of OA Description

Big osteophytes, definite narrowingof joint space, severe sclerosis, anddefinite deformity of the bone.

OARSI Grade

1 Joint Space Narrowing (0-3) 30 Sclerosis (0-3) 20 Osteophythosis (0-3) 3

Joint Space Measurements

Lateral/L1 Medial/M1 Laterality/ROI Medial/M2 Lateral/L2

7.8 7.4 7.8 7.4 8.6 7.5 6.7 6.6 Joint Space Width [mm] 1.6 1.9 3.0 4.3 10.2 10.1 9.8 9.3

Additional Measurements

7.0 6.6 7.0 6.6 7.7 6.7 6.0 5.8 Standardized JSW* [mm] 1.5 1.8 2.8 4.0 9.4 9.3 9.0 8.6

125.25 119.87 Joint Space Area [mm²] 41.82 156.29

51.10 48.90 Area Imbalance [%] 21.11 78.89

These images are notfor diagnostic use!

*Based on a normalized tibia width of 80 mm.

Soware Supported Assessment of Osteoarthritis Based on Kellgren & Lawrence | OARSI

Patient Name AnonymizedPatient ID 0Date of Birth --Accession #Date of Capture 2016-07-29

Kellgren & Lawrence (KL) Grade

0KL-Grade

(0-4) 4No signs of OA Description

Big osteophytes, definite narrowingof joint space, severe sclerosis, anddefinite deformity of the bone.

OARSI Grade

1 Joint Space Narrowing (0-3) 30 Sclerosis (0-3) 20 Osteophythosis (0-3) 3

Joint Space Measurements

Lateral/L1 Medial/M1 Laterality/ROI Medial/M2 Lateral/L2

7.8 7.4 7.8 7.4 8.6 7.5 6.7 6.6 Joint Space Width [mm] 1.6 1.9 3.0 4.3 10.2 10.1 9.8 9.3

Additional Measurements

7.0 6.6 7.0 6.6 7.7 6.7 6.0 5.8 Standardized JSW* [mm] 1.5 1.8 2.8 4.0 9.4 9.3 9.0 8.6

125.25 119.87 Joint Space Area [mm²] 41.82 156.29

51.10 48.90 Area Imbalance [%] 21.11 78.89

These images are notfor diagnostic use!

*Based on a normalized tibia width of 80 mm.


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