www.ionsigtech.com 1 ion signature technology, inc. ion signature (ist) is the leader in...

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Ion Signature Technology, Inc.

Ion Signature (IST) is the leader in deconvolution for mass spectrometry. We develop and market software for laboratories that demand accurate and highly productive chemical analysis using mass spectrometry. Our products reduce the time required to prepare and analyze complex chemical samples and interpret the data resulting in improved economics for the user.

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EPA Testimonial

EPA Quote:“Software Performance InformationThe Ion Signature Software is capable of identifying low concentrations of target analytes in the presence of high levels of matrixinterferences. By “seeing through”

the matrix interferences, the software reduces the need for sample re-analysis anddilution, and increases confidence in surrogate, internal standard, and target compound identification and quantification.”

Conversion of an Abandoned Chemical Plant to anEntertainment Complex

BrownfieldsRedevelopment

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Technology - Concept and Benefits

• Complex samples contain many components which overlap, thus producing complexity• IST software is able to “untangle” these multiple components. • The software accurately calculates and displays each individual component

Deconvolution: a mathematical technique for quickly and accurately extracting the equivalent of clean spectral data from background noise, matrix interferences or co-eluting compound peaks. Conceptually, deconvolution is similar to simultaneously solving ten or more jigsaw puzzles after putting all of the pieces in one box

• Broadly used in speech recognition, telephone processing equipment, and analytical instrumentation• Can be applied to any narrow band, time correlated

data. Line spectra are best• Mass Spectral Data is a perfect candidate for

deconvolution

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IST Software

The Unique proprietary deconvolution algorithms allow the Ion Signature software to:

Dramatically shortens runtime

Productivity: 10 – 100 fold Improvement

Sensitivity: 10 fold improvement

• Current products provide unmatched:

Accuracy Precision

Selectivity Sensitivity

Speed

Improve data quality reduces

Re-analysis rates:reduced by 50%

Data review time: reduced by 75%

Sample prep time: reduced by 50%

• Based on proprietary data analysis algorithms

“The value of our products centers on recognizing chemical entities that improve people's lives or threaten their security in seconds, not minutes or hours.”

“The value of our products centers on recognizing chemical entities that improve people's lives or threaten their security in seconds, not minutes or hours.”

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Market-Product

• Industry leading quantitative deconvolution software for mass spectrometry

• Precise, rapid target compound identification and quantification

• Unique set of advanced deconvolution algorithms that out-perform the competition

• Extract the qualifier ions for each target compound• Deconvolve the signal from all noise, matrix and

co-elution contributions• Identify, integrate and report the compounds found

The industry’s most powerful tool for untangling mass spectra

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Markets-Multiple Applications

• Petrochemicals- petrochemical composition, fingerprinting• Chemicals – QA/QC, R&D, brand equity• Environmental – air, water, soil analyses• Flavor and Fragrance – flavors and aromatics• Food and Beverage – flavors, colorings in food and drinks• Forensic- trace evidence in criminal investigations• Toxicology – drugs and poisons• Life Science –pharmaceuticals, drug discovery• Homeland Security-explosives, warfare agents analyses

The above applications may be grouped into three different equipment markets: The Laboratory Instrument MarketThe Portable Instrument MarketThe On-Site, In-Situ Probe Market

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Market Opportunities

Laboratory instrument market

Portable instrument market

On-Site In-situ probe market

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Markets - Trends in Analytical Procedures

Trends in analyses common to all applications:• Faster and faster analysis methods• Increase measurement sensitivity• Increase productivity• Reduce labor costs• Identification of target and unknown compounds• Application specific libraries• Taking the analytical capability closer to the site• The analytical tool is measured by R.O.I.

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Markets Served

• Dramatically reduce costly re-analysis rates

• Cut data review times by 75%• Replace long, complex, multi-tiered

analysis times with extremely short, simple ones

• Virtually eliminate arduous sample preparation

• Revenue gains > 10% for the user• Increased profit margins

All while maintaining or improving

data accuracy!

For Independent Testing Labs; the Key Is Throughput

45 minutes vs. 5 minutes – equivalent data quality

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EPA Confirmation of Results


Markets Served

For R & D and Manufacturing Support Labs,

the Emphasis Is on Accuracy

Accurately identify targetcompounds:In complex matricesObscured by co-eluting peaksUnder Fast GC conditions

While maintaining the industry’s:Lowest method detection limitsHighest repeatabilityFastest time to analysis

And then handle tentative identification of unknowns!


Challenges Faced by Labs Today

Interpreting mass spectra in the presence of high noise levels is one of the biggest challenges faced by labs.


Typical Complex Samples

More than 100 compounds are in this sample of PCBs, PAHs, and chlorinated pesticides.


Accurately Identify And Quantify50 Compounds In less than 10 Seconds


Compound Identification – Simple, Intuitive, Visual

Detailed view of all peaks using Ion Signature software.


Petroleum Example


Petroleum Example - Identification


Customer Testimonials

•“The software gives us insurance that we are in fact looking at the correct compound. The accuracy of our results has increased tremendously, justifying the purchase of the software.” Pernod-Ricard (#2 beverage company world-wide)

•“I am very impressed with the software. The software is easy to use. I love it!” General Motors

•“So far the software has exceeded our expectations. What was taking 11/2 hours now takes 10 seconds with the IST software. We immediately saw the productivity benefits.” North Dakota State Crime Lab

•“The software is able to pick out trace level compounds very easily. It is a wonderful screening tool.” Irish Distillers

•“The IST software was one of the most instrumental tools to help us win a 7 instrument sale.” Shimadzu, Australia

•“For complex samples the IST software is the perfect solution. We have been very pleased and surprised by our sales peoples positive response.” PerkinElmer


30 Day Free Trial

According to the EPA, "Ion Signature software reduces the need for re-analysis and dilution, and increases confidence in surrogate, internal standard, and target compound identification and quantification.“

Get a 30-day free trial of the software! Simply go to

http://www.ionsigtech.com/products/products_ionsignature_getademo.php OR

Go to our web site www.ionsigtech.com and click on “Download FREE 30 day Demo”


Contact

Contact John Moore with any follow up questions:

Tel. 401-767-4360

Email: [email protected]

www.ionsigtech.com 1 ion signature technology, inc. ion signature (ist) is the leader in...

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