why would a cell divide? as cells absorb nutrients and get larger, the volume of the cell increases...

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Ch 10 Cell Division

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Ch 10 Cell Division

Comparing Sexual and Asexual Reproduction

Why Would a Cell Divide?As cells absorb nutrients and get larger, the volume

of the cell increases faster than the surface area

This means that a cell can no longer absorb nutrients and get rid of wastes fast enough to support its demands (volume)

So what’s a cell to do?

Solution: divide in 2!

Surface area for exchange not great enough to support cell’s needs

Three reasons why cells reproduce by asexual reproduction:

1. Growth 2. Repair 3. Replacement

Different cells divide at different rates:Most mammalian cells = 12-24 hoursSome bacterial cells = 20-30 minutes

Cell Type Typical Lifespan

Intestinal Lining

?

Skin Cell ?

Red Blood Cell ?

Liver Cell ?

Intestine –Muscle and other tissue

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Cell Type Typical Lifespan

Intestinal Lining

4-5 Days

Skin Cell 2 Weeks

Red Blood Cell 4 Months

Liver Cell 300 – 500 Days

Intestine –Muscle and other tissue

16 years

Eukaryotic Cell Cycle

REMEMBER!

InterphaseProphaseMetaphaseAnaphaseTelophaseCytokinesis

IPMATC

Interphase occurs before mitosis begins

• Chromosomes are copied (# doubles)

• Cell growth and organelles are doubled

• Preparing for mitosis

Prophase 1st step in Mitosis

• Mitosis begins (cell begins to divide)

• Centrioles appear and begin to move to opposite end of the cell.

• Spindle fibers form between the poles.

Metaphase 2nd step in Mitosis

• Chromatids (or pairs of chromosomes) attach to the spindle fibers and line in middle.

Anaphase 3rd step in Mitosis

• Chromatids (or pairs of chromosomes) separate and begin to move to opposite ends of the cell.

Telophase 4th step in Mitosis

• Two new nuclei form. • Chromosomes appear

as chromatin (threads rather than rods).

• Mitosis ends.

Cytokinesisoccurs after mitosis

• Cell membrane moves inward to create two daughter cells – each with its own nucleus with identical chromosomes.

The Stages of the Cell Cycle

Regulatory Proteins Internal- Protein that regulates the

timing of the cell cycle inside the cell (ex: cyclin).

External- Protein that can cause the cell cycle to speed up or slow down (ex: growth factors, contact inhibition).

*Apoptosis*-programmed cell death.

Uncontrolled growth of cells

Cancer – body loses ability to control growth.› *Damaged P53 gene*› Causes: tobacco, radiation exposure, viral

infection, etc. Tumors- mass of cells

› Can damage surrounding area› Can break off and spread throughout body

Stem Cells Unspecialized

cells process by which

cells become specialized is known as differentiation.

Stem Cell Research

Replacing damaged heart cells.