who statement on the first meeting of the (ihr(2005...
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• WHO statement on the first meeting of the International Health Regulations (2005) (IHR(2005) Emergency Committee on Zika virus and observed increase in neurological disorders and neonatal malformations:
• The Director-General declared a Public Health Emergency of International Concern (PHEIC) on 1 February 2016
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•Zika virus (ZIKV) is an emerging
arthropod borne
virus (arbovirus) transmitted by
Aedes mosquitoes.
•The virus belongs to the genus
Flavivirus family Flaviviridae, and
is closely related to other
flaviviruses of public health
relevance including dengue
(DENV), yellow fever
CHICKUNGUNYA and West Nile
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Vector-borne Diseases of Concern (cont.) Disease Pathogen Vector Transmission
Viral
Dengue * DEN-1,2,3,4 flaviviruses Aedes aegypti mosquito Anthroponotic
Yellow fever Yellow fever flavivirus Aedes aegypti mosquito Anthroponotic
Chikungunya RNA virus that belongs to the alphavirus genus of the family Togaviridae
Aedes aegypti and Aedes albopictus, Anthroponotic
ZIKA Flavivirus Aedes aegypti Aedes mosquito species (notably Ae. africanus, Ae. albopictus, Ae. polynesiensis, Ae. unilineatus, Ae. vittatus and Ae. hensilli) are considered as potential vectors
Japanese encephalitis
flavivirus Culex species (mainly Culex tritaeniorhynchus).
Encephalitis (West Nile, Lyme, etc.)
Flavi-,alpha- and bunyaviruses Mosquitoes and ticks Zoonotic
Firlarial nematodes
Lymphatic filariasis * Brugia malayi, timori, Wuchereria bancrofti
Anopheles, Culex, Aedes mosquitoes Anthroponotic
Onchocerciasis * Onchocerca volvulus Simulium spp. blackflies Anthroponotic
* WHO neglected tropical disease
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PENYAKIT BAWAAN NYAMOK
Penyakit Chic Zika Denggi Malaria D.Kuning W.Nile JE
Vector
Agent Penyakit
Virus Chikungunya
Virus Zika
Virus Denggi
Parasit Plasmodium
Virus Yellow Fever
Virus West Nile
Virus J. Encpelatis
Rawatan khusus
Vaksinasi
Kejadian di Malaysia
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CASE DEFINITION FOR ZIKA
VIRUS INFECTION Suspected case:
• Patient with rash and one or more of the following symptoms (not explained by other medical conditions):
- Fever (>37.5°C) – Arthralgia or myalgia
– Arthritis/Periarticular Edema
– Non-purulent conjunctivitis or conjunctival hyperemia
– Presented with **Guillain-Barre Syndrome or microcephaly (age less than 1 year)
AND – Recent history of travelling to the country affected with
Zika infection (within 7 days after arrival) or history of *contact with confirm Zika case.
*person who live in the same locality with the Suspected case or history of sexual intercourse with person who had travelled to affected countries. **Signs and symptoms of Guillain-Barre syndrome may include: - Prickling, "pins and needles" sensations in your fingers, toes, ankles or wrists, Weakness in your legs that spreads to your upper body, Unsteady walking or inability to walk or climb stairs, Difficulty with eye or facial movements, including speaking, chewing or swallowing ,Severe pain that may feel achy or cramp-like and may be worse at night, Difficulty with bladder control or bowel function, Rapid heart rate, Low or high blood pressure, Difficulty breathing
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HISTORICAL SPREAD OF ZIKA VIRUS
ZIKV was first isolated from a rhesus
monkey in the Zika Forest of Uganda, in
1947 (Dick et al. 1952).
For half a century, the virus was
described as causing sporadic
human infections in Africa and
Asia,
Zika fever epidemics
took place in Yap
Island,
Micronesia (Duffy et al.
2009)
In 2013, a large epidemic
was reported in French Polynesia,
concomitant with a
dengue epidemic caused by serotypes 1 and 3
In the early 2015, records of
patients presenting a “dengue-like
syndrome” appeared in the city
of Natal state
of Rio Grande do Norte, Brazil.
laboratory findings indicated a
non-DENV and non-Chikun Pcr
CONFIRMED zIKv
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GIGITAN NYAMOK
HUBUNGAN SEX TRANSFUSI DARAH
BAYI DLM KANDUNGAN
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Kesan Jangkitan Zika:
• Microcephaly
• Guillain-Barré Syndrome
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