where does the future of pharmacoeconomics lie?

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CURRENT ISSUES Where does the future of pharmacoeconomics lie? The future of pharmacoeconomics lies in further developing both trial-based and modelling studies, improving the credibility of such studies, and identifying and catering for the needs of healthcare decision-makers, says Professor Michael Drummond from the University of York, UK. limitations in current methodology He believes that methodological limitations in current pharrnacoeconomic analyses include the use of: an inappropriate comparator; inadequate medical evidence; the wrong type of economic analysis; and a limited range of cost and outcome measures. Professor Drummond also suggests that there is an inappropriate balance between optimism for the product and conservatism in the methodological approaches used. Focus on the end-user There has been a move away from pharrnaco- economic modelling in the medical literature, compared with an increase in the use of modelling early in product development. Although more naturalistic, trial-based pharrnacoeconomic studies are being encouraged, they are not always feasible, notes Professor Drummond. Because pharmacoeconomic decision-making and communications are more likely to occur at the local health system level, consideration must be given to the costs and outcomes of the intervention in real-life practice and the transparency of results to enable interpretation in different settings. Professor Drummond adds that there is a need for standardisation of methodologies to improve the practice, interpretation, relevance and credibility of pharmacoeconomic studies. Drummond ME The future of pharmacoeconomics: bridging science and practice. Clinical Therapeutics 18: 969-978. Sep-Oct 1996 llOO487"" 1173-5503/96/0093-00051$01.00°Adls International L1mltad 1996. All rights reserved PharmacoEconomics & Outcomes News 21 Dec 1996 No. 93 5

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Page 1: Where does the future of pharmacoeconomics lie?

CURRENT ISSUES

Where does the futureof pharmacoeconomics lie?

The future of pharmacoeconomics lies in furtherdeveloping both trial-based and modelling studies,improving the credibility of such studies, andidentifying and catering for the needs of healthcaredecision-makers, says Professor Michael Drummondfrom the University of York, UK.

limitations in current methodologyHe believes that methodological limitations in

current pharrnacoeconomic analyses include the useof: an inappropriate comparator; inadequate medicalevidence; the wrong type of economic analysis;and a limited range of cost and outcome measures.

Professor Drummond also suggests that there is aninappropriate balance between optimism for theproduct and conservatism in the methodologicalapproaches used.

Focus on the end-userThere has been a move away from pharrnaco­

economic modelling in the medical literature,compared with an increase in the use of modellingearly in product development. Although morenaturalistic, trial-based pharrnacoeconomic studiesare being encouraged, they are not always feasible,notes Professor Drummond.

Because pharmacoeconomic decision-making andcommunications are more likely to occur at the localhealth system level, consideration must be given tothe costs and outcomes of the intervention in real-lifepractice and the transparency of results to enableinterpretation in different settings.

Professor Drummond adds that there is a need forstandardisation of methodologies to improve thepractice, interpretation, relevance and credibility ofpharmacoeconomic studies.Drummond ME The future of pharmacoeconomics: bridging science andpractice. Clinical Therapeutics 18: 969-978. Sep-Oct 1996 llOO487""

1173-5503/96/0093-00051$01.00°Adls International L1mltad 1996. All rights reserved PharmacoEconomics & Outcomes News 21 Dec 1996 No. 93

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