welcome to forth!medlab.cc.uoi.gr/hercules/images/pdf/agenda.pdf · 2012-02-01 · vorgia d6.2...

WELCOME TO FORTH!

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3rd Hercules Project Consortium Meeting, 2-3 September 2010,

Hercules Consortium Meeting

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Hercules Consortium Meeting2-3 September 2010

FORTH, Heraklion, Crete

Agenda

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Hercules Consortium Meeting, 2-3 September 2010

FORTH, Crete

Agenda of the meetingDay 1 Thursday, September 2nd

9:00 - 9:15 Welcome, Meeting Objectives and Organiza tional Details (Dimitris Kafetzopoulos)

9:15 – 10:45 Presentations of Work-packages

A. Bioethical and regulatory issues - progress in informed consent forms and approval procedures (Voula Tsinorema)

B. Childhood epilepsy, target cases, collection of samples (Pelagia Vorgia)

Hercules 2nd Consortium Meeting, 2-3 September 2010, Heraklion Crete

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C. Epilepsy genetics, DNA microarray platforms and methods for gene expression analysis and genotyping (Vasiliki Danilatou, Dimitris Kafetzopoulos)

10.45 – 11:15 Coffee break

11:15 – 13:15 Presentations of Work-packages -continued

D. Current trends in medical informatics and electronic health record systems (Oystein Nytroe )

E. Electronic database management system for biobank (Manolis Tsiknakis, Vangelis Kritsotakis and Aris Apostolakis)

F. Telematics systems and web-based medical collaboration within the Hercules project (Dimitris Fotiadis & Fanis Kalaitzis)

Agenda of the meeting

Day 1 Thursday, September 2nd (continued)

13:15 - 14:30 Lunch

14:30 – 16.30 Work packages’ presentations -continue d

G. Video-EEG monitoring systems and automated analysis tools (Mattheus Pediaditis)

H. Management, publicity and dissemination activities (Dimitris Fotiadis & Fanis Kalaitzis)


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H. Management, publicity and dissemination activities (Dimitris Fotiadis & Fanis Kalaitzis)

I. Concluding Remarks and Project Overview and Discussion (Dimitris Kafetzopoulos)

20:00 – 23:00 Dinner at Thalassina Fish Tavern, Kalon Limenon 27, Dilina 2810 251378

Agenda of the meeting

Day 2 Friday, September 3 rd(continued)

9:15 – 10:45 Open project discussion (Coordinated by Dimitris Fotiadis and Dimitris Kafetzopoulos )

Administrative issues• General Project Implementation Guidelines• Procurement procedures and contract assignments• Project timeline and timetable of deliverables• Critical issues for project implementation

10.45 – 11:15 Coffee break

11:15 – 13:30 Open project discussion continued


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11:15 – 13:30 Open project discussion continued

Financial issues• Budget implementation per partner and cost category• Project payments and allocation of resources

Other Pending issues• Development of a strategic plan for effective project implementation-Treatment of

delays according to the form send by the ministry• Questions to be addressed during the meeting of 8/9/2010 in Athens• Towards the ITAB 2010 and the Corfu project meeting

13:30 - 14:30 Lunch

14:30- 17:30 Separate thematic project meetings

Project Administrative Issues


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FORTH, Crete

Important Projects Implementation Parameters

Period of Eligibility of expenses: 17/05/10 - 30/04/11

Disbursal requests before 30/10/2011

Costs (mostly equipment) above 15000 Euros require procurement procedures otherwise should conform


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procurement procedures otherwise should conform to institutional regulations

All other costs (including hiring of personnel) should follow open and transparent procedures and a letter of compliance to these rules should be sent

Project timeline and timetable of activities

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FORTH, Crete

Deadline& Status

Coordinator Contributors No Title of Deliverable

20/4/1020/4/10 Tsinorema Mavridi , CharalambousVidalis , KafetzopoulosDanilatou

D1.1 Design of patients’ and legal guardians’ informed

consent form

20/4/1020/4/10 Tsinorema Chlomou , Vidalis Kalmanti , KafetzopoulosDanilatou , Nytroe

D1.2Definition of bioethics standards for the protection of

personal data, collection and management of genetic data and biobanking of human samples.

WP1. Review of Bioethical and Legal issues and Defi nition of Functional Requirements and Technical Specification s

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20/4/1020/4/10 Kafetzopoulos

DanilatouFotiadis D1.3

Technological review and market search for diagnostic tools of gene expression analysis and genotyping.

20/4/1020/4/10 Tsiknakis Pediaditis , KalmantiVorgia , Nytroe D1.4

Technological review and market search for video-EEG monitoring systems.

20/4/1020/4/10 Fotiadis Kalaitzis , NytroeD1.5

Technological review and market search for telematic and tele-communicating systems.

20/4/1020/4/10 Fotiadis Kalaitzis , PediaditisTsiknakis , Kalmanti ,

NytroeD1.6

Technological review and market search for electronic recording systems.

20/4/10 Kalmanti Danilatou ,Kafetzopoulos,Tsiknakis

D2.1Technological review and market search for biobanking

consumables and technologies.

20/4/10 Kalmanti DanilatouKafetzopoulosFotiadisTsinorema

D2.2Literature review concerning the value and applications

of biobanks, international protocols and standards.

Deadline& Status


WP2. Development of Biobank


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TsinoremaTsiknakis

of biobanks, international protocols and standards.

20/4/10 Kalmanti DanilatouKafetzopoulos D2.3

Development of a protocol of standard methods for collection, processing and storage of biological specimens.

30/12/10 Kalmanti FotiadisTsinoremaTsiknakisPediaditisVorgiaNytroe

D2.4Development of an electronic database for the

recording of clinical information and interconnection with the biobank’s database.

WP3. Post-genomics and Pharmacogenomics Research

Deadline& Status

Coordinator

Contributors No Title of Deliverable

30/4/11 Kafetzopoulos

Danilatou , Fotiadis , Tsinorema

Kalmanti , TsiknakisD3.1

Selection of gene biomarkers that are associated with treatment response. Association with clinical outcome.

30/4/11 Kafetzopoulos

Danilatou , Fotiadis ,TsinoremaKalmanti , Tsiknakis

D3.2

Blood gene expression profiling in children with CND and disease classification. Development of gene expression profiles with diagnostic and prognostic


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with diagnostic and prognostic significance.

WP 4. Medical Information Systems-EHR & Pilot Imple mentation & Evaluation of the Technological Platform Related to EHR

Deadline& Status

Coordinator

Contributors No Title of Deliverable

30/09/10 Fotiadis Kalaitzis , PediaditisDanilatou , KafetzopoulosTsiknakis , Kalmanti , Nytroe

D4.1Literature review concerning modern systems

of electronic health records and integration of post-genomic data.

30/12/10 Fotiadis Kalaitzis , Tsiknakis , PediaditisDanilatou , KafetzopoulosVorgia , KalmantiTsinorema ,

D4.2Design and development of an integrated

electronic health record


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Tsinorema ,Nytroe

electronic health record

Deadline& Status


20/4/10 Fotiadis KalaitzisNytroe D5.1

Literature review concerning modern systems of telematics and cost-effectiveness analysis.

30/04/11 Fotiadis KalaitzisTsinoremaNytroe

D5.2Development of a system of web-based

collaboration

WP5. Web-based Medical Collaboration Services


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Nytroe

Deadline& Status


30/12/10 Tsiknakis PediaditisKalmantiVorgia

D6.1 Technological platform of video-telemetry

30/3/11 Tsiknakis PediaditisVorgia D6.2 Automatic Analysis Systems

WP 6. Video-Telemetry and Automatic Analysis System s (VT/AAS) and pilot implementation and evaluation of the technical platform related to VT/AAS


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Vorgia

30/3/11 Tsiknakis PediaditisVorgiaKalmantiFotiadisTsinoremaNytroe

D6.3Clinical data-results from the application of video-

EEG monitoring in the University Hospital of Heraklion

WP7. Publicity and management

Deadline& Status


16/12/09 Fotiadis Tsinorema , KalmantiKafetzopoulosTsiknakis , Nytroe

D7.1 Consortium Agreement

20/4/1020/4/11

Fotiadis Kalaitzis , TsinoremaKalmantiKafetzopoulosTsiknakis , Nytroe

D7.2.1,D7.2.2

Annual progress reports (Financial & Implementation Progress Reports) (month 12,24)

30/4/11 Fotiadis Kalaitzis , Tsinorema


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30/4/11 Fotiadis Kalaitzis , TsinoremaKalmantiKafetzopoulosTsiknakis , Nytroe

D7.3 Final detailed progress report

30/9/10 Fotiadis Kalaitzis , Tsiknakis D7.4 Creation of a website

30/9/10 Fotiadis Kalaitzis , TsinoremaKafetzopoulos

D7.5 Creation of electronic newsletters

30/4/11 Fotiadis Kalaitzis , TsinoremaKalmantiKafetzopoulosTsiknakis , Nytroe

D7.6 Report of activities concerning publicity

Project financial issues

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FORTH, Crete

CategoryCost

UoI

UoC FORTH

NUSTSchool of

MedicineUnit of Bioethics ΙΜΒΒ ICS Total

CurrentExpecte

dCurr. Expect. Current

Expected

Current Expect.Curren

tExpecte

dCurren

tExpect

.

Management 9.000 9.000 4.000 3.000 0 0 4.000 2.000 0 0 3.000 3.000 20.000

Permanent staff

50.000 40.000 15.000 12.000 8.000 6.150 12.000 12.000 12.000 0 40.000 22.000 137.000

Personnel costs

58.500 68.500 23.500 23.500 10.000 14.250 18.500 44.225 20.500 32.500 19.250 37.250 150.250

Functional

Budget implementation plan per partner and category


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Functional costs

7.500 7.500 5.000 5.000 1.250 1.250 5.500 5.500 2.000 2.000 3.750 3.750 25.000

Equipment 10.000 10.000 45.000 48.000 3.000 2.350 36.000 22.025 3.000 3.000 3.000 0 100.000

Dissemination

5.000 5.000 1.000 2.000 0 0 1.000 0 0 0 1.000 0 8.000

Travel 10.000 10.000 4.000 3.000 2.750 1.000 6.000 2.500 2.500 2.500 5.000 9.000 30.250

Consumables 0 0 2.500 2.500 0 0 27.000 21.750 0 0 0 0 29.500

Summary 150.000 150.000 100.000 100.000 25.000 25.000 110.000 110.000 40.000 40.000 75.000 75.000 500.000

Financial issues

• Project (no)payments• Deviations in Budget categories above

15% (if any)• Request for budget amendment


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• Request for budget amendment• Internal loans

FMO rules relating to processing and deciding on requests for project modifications

• Request for a project modification in letter, fax, or email form to the Focal Point– Background information– Justification for modification


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– Justification for modification– Detailed description

Modifications that do not require budget amendment

• Certain modifications which do not affect the project implementation and thus do not require an amendment of the Grant Offer Letter or of the Grant Agreement should be decided by the FP. These modifications are: – increase in total eligible costs (up to 15%, but not more than

200,000 EUR); – increase in total project cost up to 100% (non-eligible part); – improvements in target indicators;


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– improvements in target indicators; – other modifications of the baseline and/or target indicator that

change the difference between them less than 15%; – financial transfers between budget headings or activities up to

15%;– new activities outside the scope of the project and not funded by

the grant; or – other changes of minor relevance.

Financial transfers between activities or budget headings

• The Grant Agreement contains a limit of 15% financial transfers between activities and between budget headings. A transfer beyond that limit must be justified by the project promoter and approved by the Focal Point. The PAG may consider allowing such transfers when:

– (a) the financial increase in the activity or the budget heading results in either measurable improved (increased) results which correspond to the financial increase, or as a minimum benefits the purpose and overall objective of the project; and

– (b) the financial decrease in the activities or budget headings from which the funds are taken is a result of genuine savings; and

– (c) the decrease does not result in diminished or lower quality activity or project element


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– (c) the decrease does not result in diminished or lower quality activity or project element compared to the initial plan.

• Where changes between activities and/or budget headings are the result of these activities / budget headings having been subject to a single public procurement procedure, the FMO will normally approve such changes. The term ‘single public procurement procedure’ refers to procedures when one procurement notice is issued and one contractor selected for the tasks that fall under these activities/budget headings.

• Management costs cannot be increased unless, in addition to the above reasons, the PAG deems that there are extraordinary and compelling reasons for approving such a change. Management costs cannot exceed 10% of the estimated eligible project cost.

Critical Project Implementation

Issues


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FORTH, Crete

Critical Project Implementation Issues

� Approval by Scientific & Bioethical Committees� Approval by the Personal Data Protection Authority� Update of IC and procedures (forms) according to the latest requirements� Procurement for equipment - Project payments – Budget implementation� Collection of Samples and Biobank IS� Video EEG motion events to identify and availability of Video EEG data


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� Video EEG motion events to identify and availability of Video EEG data� Post-genomic markers and signatures� Data model for clinical information, E-HR and IT and link to Biobank� Definition collaborative scenario and development of IT infrastructure� Web site and newsletter � Project Indicators� Project review and hearing on the 8th of September 2010� 3rd Consortium Meeting during ITAB2010� Project delivery

Overall objective (long term effects) Indicator Baseline Target

Health improvement of children population

Number of children 0 10%

Reduced hospitalization cost 100% 30%

Number of institutions that they will benefit from the implementation of the project

0 4

Purpose (direct and immediate effects) Indicator Baseline Target

Design of an integrated sc for effective, continuous follow-up and individualized treatment of children with chronic neurological diseases.

Development of research on the post-genomic level. Implementation of genotyping and gene-expression analysis methods (Number of advanced

analysis methods)0 3

Improvement of access of rural areas in specialised medical care. Use of technological tools for telemedicine and tele-consulting.

0 50%

Implementation of new technological standards with video-EEG monitoring for immediate and prompt diagnosis and treatment.

0 1

Results (goods and services produced) Indicator Baseline Target

PR

OJE

CT

IND

ICA

TOR

S


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Development of biobank infrastructure and services of post-genomic and pharmacogenomic research.

Number of human samples in the biobank, according to ethical and legal specifications

0 250

Number of specimens in which gene expression analysis will be performed. 0 30

Number of tools, methods, products, services that will be developed. 0 5

Medical Informatics Systems- Electronic Health Record

Computerised record of clinical and imaging data 0 100%

Electronic integration of meta-genomic data in the clinical medical record 0 30%

Integration of medical decision support tools 0 30%

Web-based services of Medical collaboration, Video-telemetry and Automatic Analysis Systems

New electronic services 0 4

Number of end-users that will benefit from the results 0 40

Number of tools, methods, products, services that will be developed. 0 6

PR

OJE

CT

IND

ICA

TOR

S

welcome to forth!medlab.cc.uoi.gr/hercules/images/pdf/agenda.pdf · 2012-02-01 · vorgia d6.2...

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