weebly clinical case study
TRANSCRIPT
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CLINICAL NUTRITION MANAGEMENT
OFSUPERIOR MESENTERIC ARTERY
THROMBOSIS
Dana Magee
ARAMARK Distance Dietetic Internship
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OVERVIEW
Disease Description
Evidenced Based Nutrition Recommendations
Case Presentation
Nutrition Care Process
Assessment
Nutrition Diagnosis
Interventions
Monitoring and Evaluation
Conclusion
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ACUTE MESENTERIC ISCHEMIA
(AMI)
Inadequate blood flow to the bowel caused by:
Non- occlusive Mesenteric Ischemia (NOMI)
Mesenteric Vein Thrombosis (MVT)
Acute Mesenteric Atrial (AMA) Embolus
Acute Mesenteric Atrial (AMA) Thrombosis
http://emedicine.medscape.com/article/191560
-overview#showall
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OCCLUSIVE MESENTERIC
ISCHEMIAEmbolus Thrombosis
50% of AMI cases 25% of AMI cases
Occurs in distal branches Occur at origin of SMA
Quick onset Gradual onset
Low collateral blood flow Larger portion of bowelaffected
Smaller portion of bowel
affected
Can affect multiple arteries
Associated with MI, mitral
stenosis, Afib, endocarditis,mycotic aneurysm,
dislodged plaque
Associated with CAD,
stroke, PAD, dehydration,MI, HF
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ACUTE MESENTERIC ISCHEMIA
Risks for AMI
Age over 50 years old
Atherosclerosis (African Americans as higher risk)
AFib
Hypercoaguable states (Critical Care)
Epidemiology
AMI accounts for .1% of hospital admissions in US
Mortality rate is 71% (AMA thrombosis is highest mortalityrate)
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SIGNS AND SYMPTOMS
Abdominal pain out of proportion to expectation
Benign abdominal exams
Fear of eating due to postprandial pain
N,V, D
GI bleed
Bad breath
AFib
Signs of sepsis
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SMA BLOCKAGE
Ischemia can lead to:
Vomiting and diarrhea
GI bleed
Necrotic bowel (8-12 hrs)
Bacterial overgrowth
Perforated bowel
Sepsis
HF
Multi- organ system failure
http://emedicine.medscape.com/article/191560-
overview#showall
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DIAGNOSIS
Aortography gold standard
Distinguish between SMA thrombosis and embolism
CT scan / ultrasound
Not as specific or sensitive Can see blockage of SMA
Can rule out other reasons for abdominal pain
Lab results helpful- not for diagnosis
CBC, PPT, acid base balance, lactate
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TREATMENT
Immediate exploratory surgery
Remove ischemic/ necrotic bowel
Embolectomy
In surgery: Peristalsis
Coloring
Doppler ultrasonography
IV fluorescent under Woodlamp
Second look surgery
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CASE PRESENTATION
Presented with abdominal pain out of proportion
Admitting diagnosis: SMA thrombosis
PMH: A-Fib, stroke, CAD, HTN, cardiomyopathy.
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http://web.uni-plovdiv.bg/stu1104541018/docs/res/skandalakis'%20surgical%20anatomy%20-
%202004/Chapter%2018_%20Large%20Intestine%20and%20Anorectum.htm
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CASE PRESENTATION
CT scan showed SMA thrombosis
Started on TPN
Exploratory laparotomy
30 cm small bowel resected, NGT decompressionSecond look surgery
GI bleed
Pacemaker
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EVIDENCED BASED GUIDELINES
Early or late parenteral nutrition: ASPEN vs. ESPEN
Casaer MP, Mesotten D, Hermans G et al
Objective: Comparing the early initiation of PN (European)
vs. late initiation of PN (American and Canadian)
Prospective, randomized, controlled, parallel- group,
multicenter trial in Belgium
Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. New England Journal of Medicine. 2011; 365 (6): 506-517.
Doi: 10.1056/NEJMoa1102662.
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EVIDENCED BASED GUIDELINES
Protocol:
2312 patients receiving PN in 48 hours
2328 patients receiving PN after seven days
Patients must be at nutritional risk
Excluded patients with BMI
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EVIDENCED BASED GUIDELINES
PN 48 hours post admission ICU
1 day shorter LOS in ICU (p
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EVIDENCE BASED GUIDELINES
Conclusion: Late initiation better outcomes for patients.
Limitations:
No glutamine in PN or other modulators
Premixed PN
No indirect calorimetry
Not double blinded study
Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. New England Journal of Medicine. 2011; 365 (6): 506-517.
Doi: 10.1056/NEJMoa1102662.
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EVIDENCE BASED GUIDELINES
ASPEN: Adult Critical Care Guidelines:
Early PN feeding with protein calorie malnutrition
Indicated with recent weight loss of 10-15%
Studies show:
Lower risk for complications (p
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EVIDENCE BASED GUIDELINES
Efficacy of Parenteral Nutrition Supplemented with Glutamine
Dipeptide to decrease Hospital Infections in Critically Ill Surgical
Patients
Estivariz CF, Griffith DP, Luo M, et al
Double blind, randomized, controlled study Objective: Effect of glutamine PN (GLN-PN) vs. standard PN
(STD-PN) on infections in critically ill surgery patients
Estivariz CF, Griffith DP, Luo M, et al. Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in
critically ill surgical patients. Journal of Parenteral and Enteral Nutrition. 2008; 32 (4): 389-402. doi: 10.1177/0148607108317880.
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EVIDENCE BASED GUIDELINES
Methods:
2 Cohorts: pancreatic necrosis surgery and
cardiac/vascular/colonic surgery
Ages 18-80
s/p one of five surgeries
Required PN for at least 7 days
Estivariz CF, Griffith DP, Luo M, et al. Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in
critically ill surgical patients. Journal of Parenteral and Enteral Nutrition. 2008; 32 (4): 389-402. doi: 10.1177/0148607108317880.
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EVIDENCE BASED GUIDELINES
GLN- PN
30 subjects
0.5 g/kg/day glutamine
with 1 g/kg/day amino
acid solution
STD- PN
29 subjects
1.5 g/kg/day amino acid
solution
Estivariz CF, Griffith DP, Luo M, et al. Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in
critically ill surgical patients. Journal of Parenteral and Enteral Nutrition. 2008; 32 (4): 389-402. doi: 10.1177/0148607108317880.
Limitations:
Availability of glutamine- two time periods of
research
Limited number of postoperative PN
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EVIDENCE BASED GUIDELINES
No significant changes in infection in the pancreatic cohort
In non- pancreatic cohort GLN- PN
Decrease in total infections (p
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EVIDENCE BASED GUIDELINES
Critical Illness Nutrition Practice Guidelines 2012
Recommend glutamine considered in treatment for critically ill
Associated with decreased risk of infection
Not sufficient evidence for decreased LOS, intubation
period, medical cost, or mortality
Academy of Nutrition and Dietetics. Recommendations Summary CIU: Supplemental Glutamine. Evidence Analysis Library.
http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201. Accessed March 22, 2013.
http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201 -
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EVIDENCE BASED GUIDELINES
Aspen Adult Critical Care Guidelines
Recommend 0.5 g/kg/day glutamine in PN
Associated with decreased risk of infection, LOS, and mortality
McClave SA, Martindale RG, Vanek VW, et al. Guidelines for the Provision and Assessment of Nutrition Therapy in Adult Critically
Ill Patient. Journal of Parenteral and Enteral Nutrition. 2009; 33 (3): 285-290. Doi: 10.1177/0148607109335234.
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NUTRITION CARE PROCESS
Assessment: Client History
A-Fib uncontrolled
Does not work
Lives at home with a caregiver
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NUTRITION CARE PROCESS
Assessment: Food/Nutrition-Related History:
Poor appetite after stroke, 40 pound weight loss
Patient reported 11 pound weight loss in one week
PTA following a low fat diet
Assessment: Nutrition-Focused Physical Findings:
Nausea and vomiting X two days
Abdominal pain out of proportion to expectation
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NUTRITION CARE PROCESS
Assessment: Anthropometric Measurements
Height discrepancies 62-71 inches
Weight 145 pounds
BMI 22.79
Usual weight 156 pounds
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NUTRITION CARE PROCESS
Assessment: Nutrient Needs
Energy: 1650-1848 kcal
(25-28 kcal/kg actual body weight)
Protein 79-99g protein
(1.2-1.5g/kg actual body weight)
Fluid needs: 1680-1890 ml
(25-30 ml/kg actual body weight)
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NUTRITION CARE PROCESS
Assessment: ARAMARK Nutrition Status Classification
Nutrition Care Indicator Category
Highest Points Assigned
Nutrition History 3 (poor appetite and vomiting)
Feeding Modality/Nutrition Care Order
4 (anticipated TPN)
Unintentional Weight Loss 4 (greater than 2% weight loss in one
week)
Weight Status 0
*Serum Albumin or Pre-albumin
0
Dx/Condition 3 (anticipated GI surgery)
TOTAL POINTS 14 Nutritionally severely compromised
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NUTRITION CARE PROCESS
DRG Coding
Weight loss of 5-10% of usual body weight
Albumin 3.5-5
Mild Protein calorie malnutrition
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NUTRITION CARE PROCESS
Nutrition Diagnosis
Inadequate oral intake related to GI distress as evidenced by
NPO diet order, 0% intake and not meeting estimated kcal or
protein needs.
Inadequate parenteral infusion related to parenteral prescriptiondoes not meet estimated nutritional needs as evidenced by
parenteral regimen providing 67% of estimated caloric needs.
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NUTRITION CARE PROCESS
Interventions
Once PICC is functional initiate day one TPN. 1700 ml volume:
70g protein, 150g CHO, 15g lipid.
Day two recommend 1700 ml volume: 80g protein, 255g CHO,
and 15g lipids to provide 1337 kcal, 80g protein, GIR 2.68 (81% ofnutritional needs)
Increase CHO in TPN to 255g.
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NUTRITION CARE PROCESS
Monitoring and evaluation
Food and nutrient intake: Parenteral nutrition administration
Monitor parenteral access
Food and nutrient administration: Parenteral nutrition intake
formula/ solutionAnthropometric Measurements: Body weight
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MONITORING AND EVALUATION
Biochemical data, medical tests, and procedures: Electrolytes
and renal profile potassium, magnesium, and phosphorus
Biochemical data, medical tests, and procedures: glucose
endocrine profile, glucose casual
Nutrition- focused physical findings: Digestive system: returnof GI function.
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CONCLUSION
SMA thrombosis, NPO
Patient reported recent significant weight loss, TPN initiated
Small bowel resection
NGT suctioning, GI bleed, low hemoglobin, multiple transfusions
Pacemaker, NPO
Aspiration, Chopped, nectar thickened liquids
Weaning off TPN with cardiac diet
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CONCLUSIONS
Late initiation of PN linked to decreased LOS, time on dialysis,
time on ventilator, ad risk for infections
Early PN support in patients that are admitted to the ICU
malnourished for less complications
Consideration of adding glutamine to PN for patients in the ICU,especially surgical patients
Decrease infections
More research on LOS and mortality
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REFERENCES
Dang CD. Acute Mesenteric Ischemia. Medscape.http://emedicine.medscape.com/article/189146-overview. Updated February 22, 2013.Accessed March 22, 2013.
Tessier DJ. Mesenteric Artery Thrombosis. Medscape.http://emedicine.medscape.com/article/191560-overview. Updated January 6, 2012.Accessed March 22, 2013.
American Heart Association. What is Atrial Fibrillation (AFib or AF)?. American HeartAssociation. http://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-
is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsp. Updated October 18, 2012.Accessed March 22, 2012.
American Heart Association. Coronary Artery Disease- Coronary Heart Disease. AmericanHeart Association.http://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsp. Updated February 27, 2013.Accessed March 22, 2013.
American Heart Association. Prevention and treatment of High Blood Pressure. American
Heart Association.http://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsp.Updated June 6, 2012. Accessed March 22, 2012.
http://emedicine.medscape.com/article/189146-overviewhttp://emedicine.medscape.com/article/191560-overviewhttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/HighBloodPressure/PreventionTreatmentofHighBloodPressure/Prevention-Treatment-of-High-Blood-Pressure_UCM_002054_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/More/MyHeartandStrokeNews/Coronary-Artery-Disease---The-ABCs-of-CAD_UCM_436416_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://www.heart.org/HEARTORG/Conditions/Arrhythmia/AboutArrhythmia/What-is-Atrial-Fibrillation-AFib-or-AF_UCM_423748_Article.jsphttp://emedicine.medscape.com/article/191560-overviewhttp://emedicine.medscape.com/article/191560-overviewhttp://emedicine.medscape.com/article/191560-overviewhttp://emedicine.medscape.com/article/189146-overviewhttp://emedicine.medscape.com/article/189146-overviewhttp://emedicine.medscape.com/article/189146-overview 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REFERENCES
McClave SA, Martindale RG, Vanek VW, et al. Guidelines for the Provision and Assessmentof Nutrition Therapy in Adult Critically Ill Patient. Journal of Parenteral and Enteral Nutrition.2009; 33 (3): 285-290. Doi: 10.1177/0148607109335234.
Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically illadults. New England Journal of Medicine. 2011; 365 (6): 506-517. Doi:10.1056/NEJMoa1102662.
Estivariz CF, Griffith DP, Luo M, et al. Efficacy of parenteral nutrition supplemented withglutamine dipeptide to decrease hospital infections in critically ill surgical patients. Journal ofParenteral and Enteral Nutrition. 2008; 32 (4): 389-402. doi: 10.1177/0148607108317880.
Academy of Nutrition and Dietetics. Recommendations Summary CIU: SupplementalGlutamine. Evidence Analysis Library.http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201. AccessedMarch 22, 2013.
International Dietetics & Nutrition Terminology (IDNT) Reference Manual Third Edition.Chicago, IL: American Dietetic Association; 2011.
ARAMARK. Patient Food Services Policies & Procedures Volume IV. Updated March 10,
2010. ARAMARK. Malnutrition Assessment & Diagnosis (DRG coding form).
Pronsky ZM, Crowe JP. Food Medication Interactions 16thEdition. Birchrunville, PA: Food-Medication Interactions; 2010.
http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201http://andevidencelibrary.com/template.cfm?template=guide_summary&key=3201