VTT TECHNICAL RESEARCH CENTRE OF FINLANDwww.vtt.fi

Additional information

JouniAhtinenKeyAccountManagerTel.+358503531145Jouni.Ahtinen@vtt.fi

HannuLampolaVicePresidentBiotechnology,pharmaceuticalandfoodindustriesTel.+358400530994Hannu.Lampola@vtt.fi

VTT - YOUR EXPERIENCED AND INNOVATIVE PARTNER

•Strongtrackrecordwithindustrialcustomersandprojectwork

•ExperienceandR&Dsupportalsocoverssmallstart-ups

•3,200employees,ofwhich300inbiotechnology

•UniquecombinationofdifferenttechnologiesacrossthewholeofVTT

•Reliability–over70yearsofinnovation

Wehavedevelopedseveralinnovativeproductionprocessesforourindustrialcustomers.Oursugarplatformtechnologyisbasedonbiomasshydrolysisandfermentationofsugarsintoindustrialproducts.Accordingtothecustomer´sneedwecanfocusontheoptimisationof a single process stepordevelopa novel conceptallthewayfrom biomass to product.

www.vtt.fi

BIOMASS PRE-PROCESSING

• Biomass composition and structure analysis

• Evaluation of pretreatment techniques

• Biomass fractionation

ENZYMATIC HYDROLYSIS

• Optimisation of enzyme mixture and process conditions

• Technology for the production of hydrolytic enzymes

FERMENTATION

• Production host engineering

• Bioprocess development and scale-up

• Simultaneous C5 and C6 fermentation

CONSOLIDATED BIOPROCESSING

• Production of hydrolytic enzymes and fermentation in the same production host

• Techno-economic evaluation of different process concepts

PROOF OF CONCEPTIN PILOT SCALE

Technology and market foresight • Strategic research • Product and service development • IPR and licensing • Assesments, testing, inspection, certification • Technology and innovation management • Technology partnership

SUGAR PLATFORM - VTT´S TECHNOLOGY OFFERING

industrial biotechnologyCreatingbusinessfrom

TiinaNakari-SetäläVicePresidentValuenetworksTel.+358408215794Tiina.Nakari-Setala@vtt.fi

Tailor-made production organisms

• biofuels• pharmaceuticals• bioplasticsandbiochemicals• foodandcosmeticingredients• industrialenzymes

Synthetic biology

• pathwaydesignandengineering• developmentofintracellular

regulatorycircuits

Biorefinery development

• pilotingofdifferentprocess conceptsfrombiomasstoproduct

• techno-economicfeasibilitystudies• optimisationofhydrolysisand

fermentationinhighconsistencyconditions

• versatilesmallandbenchscalebioreactorfacilities

• productioninfullyequipped1200lbiomanufacturingpilotplant

Improvement of protein production

VTThasbeengainingexperienceofTrichodermatechnologyandproteinproductionsincethe70s.Wethereforehavetheknowledgeforunderstandingthemolecularbackgroundandphysiologybehindproteinproduction.

From renewable feedstocks to sustainable industrial solutions

VTT BIOTECHNOLOGY OFFERING

Enzymes for industrial applications

• totalandtargetedhydrolysisoflignocellulose

• foodprocessing• pulpandpaperindustry• biosensorsandbiofuelcells• modificationandfunctionalisation

ofbiomolecules

Discovery of new enzymes and engineering of enzyme properties

• classicalscreening• screeningfrommetagenomic

librariesandavailablegenomes• rationalandrandomapproaches

forproteinengineering

VTT Culture Collection

• collectionof6000micro-organisms

Recent solutions for our customers• Bioethanol – from lignocellulose to ethanol using consolidated bioprocessing• Bioplastics - lactic acid production in yeast• Plant biotechnology – cloudberry stem cells as a bioactive cosmetic ingredient• Characterisation of bacterial strains and enzymes for lignocellulose hydrolysis and fermentation• Improvement of enzyme properties e.g. thermostability

Recent biotechnological advancements have challenged the oil-based industry with solutions based on renewable resources. VTT develops new process concepts for the production of biobased products for its customers. We have strong expertise in the engineering of efficient biological production hosts for different industrial applications.

Biotechnological utilisation of plants

Theversatilityofthecompoundsnaturallyproducedbyplantsoffersinterestingpossibilitiesfornovelproductionconcepts.Weutiliseplantcellculturesfortheproductionofrecombinantproteinsandsecondarymetabolitesinbioreactorenvironment.

VTT TECHNICAL RESEARCH CENTRE OF FINLANDwww.vtt.fi

Additional information

JouniAhtinenKeyAccountManagerTel.+358503531145Jouni.Ahtinen@vtt.fi

HannuLampolaVicePresidentBiotechnology,pharmaceuticalandfoodindustriesTel.+358400530994Hannu.Lampola@vtt.fi

VTT - YOUR EXPERIENCED AND INNOVATIVE PARTNER

•Strongtrackrecordwithindustrialcustomersandprojectwork

•ExperienceandR&Dsupportalsocoverssmallstart-ups

•3,200employees,ofwhich300inbiotechnology

•UniquecombinationofdifferenttechnologiesacrossthewholeofVTT

•Reliability–over70yearsofinnovation

Wehavedevelopedseveralinnovativeproductionprocessesforourindustrialcustomers.Oursugarplatformtechnologyisbasedonbiomasshydrolysisandfermentationofsugarsintoindustrialproducts.Accordingtothecustomer´sneedwecanfocusontheoptimisationof a single process stepordevelopa novel conceptallthewayfrom biomass to product.

www.vtt.fi

BIOMASS PRE-PROCESSING

• Biomass composition and structure analysis

• Evaluation of pretreatment techniques

• Biomass fractionation

ENZYMATIC HYDROLYSIS

• Optimisation of enzyme mixture and process conditions

• Technology for the production of hydrolytic enzymes

FERMENTATION

• Production host engineering

• Bioprocess development and scale-up

• Simultaneous C5 and C6 fermentation

CONSOLIDATED BIOPROCESSING

• Production of hydrolytic enzymes and fermentation in the same production host

• Techno-economic evaluation of different process concepts

PROOF OF CONCEPTIN PILOT SCALE

Technology and market foresight • Strategic research • Product and service development • IPR and licensing • Assesments, testing, inspection, certification • Technology and innovation management • Technology partnership

SUGAR PLATFORM - VTT´S TECHNOLOGY OFFERING

industrial biotechnologyCreatingbusinessfrom

TiinaNakari-SetäläVicePresidentValuenetworksTel.+358408215794Tiina.Nakari-Setala@vtt.fi