Value Brief

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The ANTHEM™ Total Knee System is designed to meet the needs of all stakeholders.

SURGEONThe ANTHEM Total Knee System builds upon established design fundamentals, while incorporating advanced features to improve implant fit, enhance the surgical experience, and reduce clinical compromise. After extensive research in conjunction with global experts, the ANTHEM design has been optimized to provide a better implant fit for a wider range of patient anatomies 1. Built upon the clinically successful technology based on the GENESIS™ II design and its nearly 20 years of clinical data, the ANTHEM knee provides the same clinically proven articulation 2,3,4.

The ORTHOMATCH™ Universal Instrumentation platform reduces the number of surgical steps in a three tray configration*. By use of multifunction, ergonomic, and modular instruments the surgical flow is streamlined, while not sacrificing intraoperative flexibility.

PATIENTConceived to satisfy the unmet needs of the global patient, the ANTHEM Total Knee System is based on a trusted design that has provided reliable pain relief and improvement in knee function to TKA patients for over 15 years. The fit of the ANTHEM implant has been specifically developed to accommodate the differences seen in the size and shape of patients bones from diverse population groups worldwide.

The ANTHEM knee has been designed to deliver improved value for those undergoing medical care with a goal to make total knee replacement more accessible, more affordable and more appropriate without compromising on quality, functional outcome, or implant longevity.

PROVIDERWith increased social awareness related to Total Knee Arthroplasty, higher expectations from patients, and increasing pressure on hospital budgets, healthcare providers demand reliable, high quality products that are both cost effective and continue to improve patient outcomes1. The ANTHEM knee system offers exceptional value in Total Knee Arthroplasty by harnessing cutting edge technological advances while incorporating local insights and design inputs3. By offering a total knee system in a three tray configuration, significant cost saving can be realized by reduced processing and sterilization, in addition to significant procedural efficiency gains in the operating room. To facilitate tangible economic value realization for payers, the ANTHEM knee is also is coupled with Syncera™, a progressive operating model offering a portfolio of value solutions personalized to customers needs.

With a continued dedication to innovation, the ANTHEM Total Knee System drives enhanced value to all facets of the healthcare system, providing tangible advantages for arthroplasty surgeons, patients and healthcare providers

* when utilizing polymer femoral trials

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Advanced technology• Equivalent implant tibio-femoral kinematics and articulation

to the clinically successful GENESIS II design 2,3,4

• Patella Friendly S-curve funnels patella to facilitate tracking toward midline in deep flexion

• Hi Flexion insert accommodates up to 155 degrees of flexion• Tibial base plate with patented DURAHONE™ Advanced Finishing

technology surface finish to reduce surface roughness and to decrease micromotion minimizing hackside wear

• The ANTHEM Knee System is compatible with all GENESIS and LEGION™ tibial inserts and tibial baseplates for addition of stems and wedges for complex primary procedures

The ANTHEM Total Knee System was designed to provide an advanced and globally relevant prosthesis and instrumentation system while being accessible to all arthroplasty surgeons and patients.

Improving anatomic implant fit• Enhanced femoral and tibial anatomic implant fit for all patients• Anthropometrically optimized low profile femoral anterior

flange to reduce incidence of overhang• Bone conserving femoral PS box design preserving intercondylar notch bone stock• Anatomic asymmetric tibial baseplate design with shorter, medialized tibial stem to

suit a wider range of anatomies

Effciency through intelligent design• ORTHOMATCH Universal Instrumentation platform encompasses

a comprehensive primary TKA system in just three trays*• Efficient, Intuitive, and Effective system providing

streamlined and reproducible surgical flow• State of the art low weight, durable materials with reduced

instrument footprint to reduce hospital costs

• The ANTHEM knee system is a total knee prosthesis with advanced femoral and tibial anatomic design to promote improved anatomic implant fit for all patients globally 4

• The ANTHEM knee system is based upon trusted design pedigree incorporating clinically advanced technology such as the tibio-femoral articulation and patello-femoral function equivalent to the GENESIS™ II Total Knee System, which exhibits a 98% survivorship at 15 years 5,6

• The ANTHEM Total Knee System coupled with ORTHOMATCH™ Universal Instrumentation platform has been developed in conjunction with leading surgeons from Emerging Markets and Europe proving benefits by creating efficiency through intelligent design which translates into tangible value for surgeons, patients and healthcare providers

* ORTHOMATCH three Tray configuration includes polymer femoral trails

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References

1. ANTHEM AdAM (Anatomical Data Mining) CT data utilsing Caucasian, Chinese, India, Middle Eastern and African data sets . Data on file

2. Smith & Nephew, Inc. ANTHEM™ PS Total Knee System: 510(k) Summary. Pg E2-1-2

3. Bourne et al. Survivorship of the Genesis II Total Knee Arthroplasty at a Mean of 15 years. COA poster presentation. 2014.

4. Victor et al, Total knee arthroplasty at 15–17 years: Does implant design affect outcome? International Orthopaedics; 2014. 38:235–24

5. Wei, David H., et al. “Improving Value in Musculoskeletal Care Delivery.”The Journal of Bone & Joint Surgery 97.9, 2015

6. Hwang J, Christensen C, Disruptive Innovation in Health Care Delivery: A framework for Business Model Innovation, Health Affairs, 2008

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Telephone: 901-396-2121Information: 1-800-238-7538Orders/inquires: 1-800-238-7538www.smith-nephew.com

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