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TRANSCRIPT
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Functional considerations of the Vagus nerve:
An Endobiogenic perspective
Kamyar M. Hedayat, MDPresident, American Society of Endobiogenic Medicine and Integrative Physiology
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Overview
• Endobiogeny: A theory of terrain• Types of Adaptation• Function of the Vagus nerve• Vagotonia and foundation of disease• ANS and Adaptation• Assessment of vagal excess• Conclusions
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Endobiogeny: A theory of terrain
• Presented by French physician Christian Duraffourd, MD in the early 1980’s
• Terrain: functional expression of structural constitution in its internal equilibrium– Dynamic and Ceaseless– Consists of Inductive and Reactive elements
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Endobiogeny: A theory of terrain
• Terrain– Constitution: Genetic heritage, potential capacity
of the structure– Structure: materialized constitutive elements that
assure life. The achievement of constitution– Function: all the biologic and metabolic mechanics
that assure functioning of structure and dynamics of the organism
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Endobiogeny: A theory of terrain
• Morphology: Exterior configuration of structure in its function
Vagotonic 18 yo female with Migrainesseizuresceliac
Vagotonic 6 yo male with moderately severe asthma, eczema
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States of adaptation
• Adaptation: Momentary adjustment of equilibrium
• General adaptation syndrome (GAS): response to a non-recognized attack; progressive, ordered, and chronologic
• Adaptability: Adaptation to a new level of functioning without invoking GAS
• Adaptative states: Adaptation that does not return to the prior state of equilibrium
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ANS and Adaptation
• Parasympathetic– Origin: Cranial nerve: Pons– Nerve: Vagus nerve– Neurotransmitter: Acetyl Choline– Functions: Rest and digest:• Basal physiologic state• Increases the rate of production and volume of all
secretions, facilitates sleep and stillness• Solicits alpha-sympathetic activity
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Vagotonia and disease
• Vagotonic individuals susceptible to disorders due to parasympathetic hyper-functioning– DERM: Eczema, Psoriasis– PULM: Asthma, Bronchitis– CNS: Migraines– GI: Crohn’s disease, Ulcerative colitis, Gastritis
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ANS and Adaptation
• Alpha-sympathetic– Origin: Locus ceruleus, Pons– Nerve: Sympathetic Ganglion– Functions: Initiates, calibrates and/or maintains each type
of adaptation state, installs tension• Beta-sympathetic– Origin: Adrenal medula, Adrenal gland– Nerve: N/A, neurohoromone– Functions: facilitates movement, relieves tension through
the excretion of secretions, regulates serum glucose levels
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Global ANS Function
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ANS Dynamism and Entrainment
Alpha Sympathetic
Beta Sympathetic
Para Sympathetic
SEROTONIN CORTISOL
HISTAMINE
AUTONOMIC NERVOUS SYSTEM
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Altered ANS equilibrium: POTS
Alpha Sympathetic
Para Sympathetic
SEROTONIN
HISTAMINE
ANXIETY
Beta Sympathetic
CORTISOL
TACHYCARDIAVOMITING
Venodilation
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Assessment of Para: History
• Infancy: Quiet, easy baby, good eater• Toddler: Shy, timid; ENT pathologies,
Pulmonary pathologies• Adolescence: Sweats easily and throughout
body, falls asleep easily• General: Hungry first thing in morning,
abundant saliva
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Assessment of Para: Exam
• General: Round face• General signs of
digestive insufficiency– Enlarged parotids, dilated
canal of Stenon, tenderness of pancreas
• Signs of post-pubertal growth hormone related to the above– Bulbous nose, fleshy ear
lobes, large chin
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Conclusions
• 10th cranial nerve has an impact on nearly every aspect of basal and adaptive physiologic activity
• Contextualize Vagus nerve activity within the scheme of global functioning of the patient
• Endobiogeny offers a sophisticated method of evaluating functional implications of vagus dysfunction in psychological, mental and physical spheres
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Opportunities for learning
• ASEMIP offers fellowship in Endobiogeny:– History taking and physical exam skills– Systems-based evaluation of biomarkers– Phytotherapy, Aromatherapy, Diet, lifestyle guidance
• Applications being considered for 2014-2016 teaching cycle: www.endobiogeny.com
• To learn more and receive a free copy of this lecture:– Text: “Endo” to 619-456-0155– Email: [email protected]– Call: 858-455-9726
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Questions and Answers