untangling the effects of white-nose syndrome on endangered bats · 2019-03-29 · dr. tina cheng....
TRANSCRIPT
Wings in the Night:
Untangling the effects of white-nose syndrome
on endangered bats
Dr. Christina DavyTrent University / [email protected]; @Christina_Davy Photo: Brock and Sherri Fenton
Photo: Joe Crowley
Photo: Heather Fotherby
Dr. Vikram Misra
Dr. Mike Donaldson
Dr. Chris Kyle
Dr. Gaby Mastromonaco
Dr. Craig Willis
Photo: Brock and Sherri Fenton
Foley et al. 2018 Science Advances
Ind
ex o
f lo
nge
vity
Log (body mass) (g)
Photo: Brock Fenton
Photo: Nancy Heaslip
Photo: Karen Vanderwolf
Photo
: Anne F
roschau
er
1,142 little brown bats14 microsatellite loci
Red star = most westerly record of WNS
Davy et al. 2017, FACETS
Davy et al. 2017, FACETS
Donaldson, Davy, Willis, McBurney, Park and Kyle (2017) Evolutionary Applications
Evidence for local immunogenetic adaptation
Evidence for direct selection by WNSon immune genes
Inferred in M. lucifugus from SNPs in 138 immune genes and their regulatory regions
Do we see a signature of immunogenetic selection related to WNS?
Yes (so far, in little brown bats)
Hooton, Cameron, Hale, Fenton, and Davy in review
Dr. Tina Cheng
Hypothesis: the fungal pathogen and the different bat hosts exhibit reciprocal, context-dependent molecular responses.
Davy, Donaldson, Willis, Saville, McGuire, Mayberry, Wilcox, Wibbelt, Misra, Bollinger and Kyle (2017, 2018) Ecology and EvolutionDavy, Donaldson, Willis, Pikula […] and Kyle (in prep.)
Do in vitro studies accurately represent the response of the fungus to bats?
Does the fungus respond the same way among in vitro conditions?
Dr. Mike Donaldson Karen Vanderwolf
Donaldson, Davy, Vanderwolf, Willis, Saville and Kyle (2018), Mycologia
Does the fungus respond the same way on bats and culture plates?
North American
Little brown bat
(Myotis lucifugus)
WNS-susceptible
North American
big brown bat
(Eptesicus fuscus)
WNS-tolerant
European
greater mouse-eared bat
(Myotis myotis)
WNS-tolerant
Davy, Donaldson, Willis, Pikula […] and Kyle (in prep.)
Davy, Donaldson, Willis, Pikula […] and Kyle (in prep.)
Tolerant big brown batsSusceptible little brown batsTolerant greater mouse-eared bats
Davy, Donaldson, Willis, Pikula […] and Kyle (in prep.)
Cluster dendrogram grouping samples by similarity of gene
expression
Tolerantgreater mouse-eared bats
Tolerant big brown bats
Susceptible little brown bats
Davy, Donaldson, Willis, Pikula […] and Kyle (in prep.)
Lesion-positive wing tissueLesion-negative wing tissue
The Accidental Pathogen?
Whoops!
Sonu Subudhi Dr. Vikram Misra
Davy, Donaldson, Rapin, Subudhi, et al., 2018, Scientific Reports
Gene expression (ileum) varies among Pd-infected, CoV-infected, and coinfected Myotis lucifugus
Context Matters
Davy, Mastromonaco, Riley, Baxter-Gilbert, Mayberry, and Willis. (2017), Conservation Biology
Does the pathogen’s impact reach past the point of recovery?
Claw sampling
Cortisol deposition
Davy, Mastromonaco, Riley, Baxter-Gilbert, Mayberry, and Willis. (2017), Conservation Biology
Naïve Exposed Naïve Exposed
Davy, Mastromonaco, Riley, Baxter-Gilbert, Mayberry, and Willis. (2017), Conservation Biology
Does the pathogen’s impact reach past the point of recovery?
Photo: Brock Fenton Photo: Laura Scott
Dr. Thomas Jung
Brian Slough
Val Von Zuben
Davy, Von Zuben, Slough and Jung (in preparation)
Forearm
Davy, Von Zuben, Slough and Jung (in preparation)
0 10,000 20,000 30,000 40,000
"Aquatic habitat""Marine habitat"
Freshwater habitat"Riverine habitat""Littoral habitat"
"Terrestrial habitat""Desert habitat"
"Montane habitat""Woodland habitat"
"Aerial habitat"
Google Scholar results
Also reference “conservation”
Do not reference “conservation”
Google Scholar search results (September 6, 2015) for representation of selected habitat types in scientific literature.
Aerial habitats are under-represented in the literature
292 records; 53 referring to the airspace as habitat
Davy, Ford and Fraser (2017), Conservation Letters
Davy, Ford and Fraser (2017), Conservation Letters
Aerial species are well-represented in global lists of SAR. Yet aerial habitats are not defined.
Data from the International Union for the Conservation of Nature
Habitat classifications for the airspace
Davy, Ford and Fraser (2017), Conservation Letters
Photo: Susan Heaslip, DFO Photo: Jeol Trick, USFWS
Eel and Warbler
Basoaerial habitat fragmentation (0-1 km altitude)
Red= airportsBlue = cities
Black= roads White = windfarms
Purple = FCC communications towers
Davy, Ford and Fraser (2017), Conservation Letters
Photo: Brock Fenton
Aerial habitat fragmentation can be quantified using existing tools from terrestrial ecology
Davy, Ford and Fraser (2017), Conservation Letters
Photo: Lauren Hooton
Lauren Hooton
