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HPV vaccination in IndonesiaSetiawan, Didik

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Citation for published version (APA):Setiawan, D. (2017). HPV vaccination in Indonesia: A health-economic & comparative perspective.University of Groningen.

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________________________________________________

HPV Vaccination in Indonesia:

a Health-economic & Comparative Perspective

________________________________________________

Didik Setiawan

Paranimphs:

Adhyatmika

Jurjen van der Schans

The work presented on this thesis was funded by the Directorate General of Higher Education (DIKTI),

Ministry of Research and Higher Education, Republic of Indonesia. Printing of this thesis was financially

supported by the University of Groningen, the Graduate School of Science (GSS) and Institute of Science

in Healthy Aging & healthcaRE (SHARE)

Cover design : Doti P Martono

Layout : Didik Setiawan

Printing : Off Page (www.offpage.nl)

ISBN: (book) : 978-90-367-9490-9

ISBN: (electronic version) : 978-90-367-9489-3

© 2017 Didik Setiawan. No part of this thesis may be reproduced or transmitted in any form or by any

means without permission from the author. The copy right of previously published chapters of this

thesis remains with the publisher or journal.

HPV Vaccination in Indonesia A Health-economic & Comparative Perspective

PhD thesis

to obtain the degree of PhD at the

University of Groningen

on the authority of the

Rector Magnificus Prof. E. Sterken

and in accordance with

the decision by the College of Deans.

This thesis will be defended in public on

Friday 17 February 2017 at 16.15 hours

by

Didik Setiawan

born on 27 July 1983

in Yogyakarta, Indonesia

Supervisors

Prof. M.J. Postma

Prof. B. Wilffert

Co-supervisor

Dr. J.A. Thobari

Assessment Committee

Prof. T.S. van der Werf

Prof. H.J. Guchelaar

Prof. I. Dwiprahasto

To my Beloved Family:

Rosel – Najwa - Nafi – Maryam

Thank you for all your support and love

TABLE OF CONTENTS

Chapter 1 General Introduction:

Prophylactic HPV vaccination: challenges

and opportunities for two different worlds

9

Chapter 2 Reviewing cost-effectiveness of HPV-

vaccination on top of screening in the

specific Dutch context

21

Chapter 3 Immunogenicity and safety of human

papillomavirus (HPV) vaccination in Asian

populations from six countries: A meta-

analysis

51

Chapter 4 The health-economic studies of HPV

vaccination in South East Asian Region: A

Systematic Review

75

Chapter 5 Health-related Quality of Life of Patients

with HPV-related cancers in Indonesia

99

Chapter 6 Cost Utility Analysis of Human

Papillomavirus Vaccination and cervical

screening on cervical cancer patient in

Indonesia

119

Chapter 7 Assessment of the broader economic

consequences of HPV prevention from a

government-perspective: A fiscal analytic

approach

143

Chapter 8 General Discussion:

Introducing Human Papillomavirus vaccine

in Indonesia: A comprehensive review and

policy recommendation

161

Summary 187

Samenvatting 191

Ringkasan 195

Acknowledgment 199

List of Publication 203

Curriculum Vitae 205

Research Institute SHARE 207