unicystic ameloblastoma with diverse histological variants and hyaline ring granulomas

1
FERNANDA GONÇALVES SALUM, KAREN CHERUBINI, VINICIUS DUVAL DA SILVA, MARIA ANTONIA ZANCANARO DE FIGUEIREDO. PONTIFICAL CATH- OLIC UNIVERSITY OF RIO GRANDE DO SUL. Woman, 22, was referred to a specialized service with alleged gum injury that had developed over 7 days. She also reported discomfort, pressure, fever, and facial asymmetry. Intraoral exami- nation detected a rm nodule at the buccal aspect of the right mandibular region that was attached to the bony tissues and was reddish purple. It was covered by ulcerated mucosa and measured 2 cm in diameter. Imaging studies revealed a radiolucent lesion involving the rst and second premolars with disruption of cortical bone and bony crest. Incisional biopsy was performed. Histopath- ological and immunohistochemical ndings were consistent with undifferentiated high-grade sarcoma. Due to the aggressiveness of the disease, the treatment of choice was hemimandibulectomy fol- lowed by mandibular reconstruction, neck dissection, and chemo- therapy. Subsequently, the patient suffered complications and postponed aesthetic surgical interventions. During clinical follow- up for 10 months no signs of recurrence developed. PE-327 - UNICYSTIC AMELOBLASTOMA WITH DIVERSE HISTOLOGICAL VARIANTS AND HYALINE RING GRANULOMAS. JOSÉ BURGOS PONCE, HELITON GUSTAVO DE LIMA, TAIANE PRISCILA GARDIZANI, MOACYR TADEU VICENTE RODRIGUES, RODRIGO QUEIROZ ALEIXO, FABRICIO GUIMARÃES DE SOUZA, VANESSA SOARES LARA. BAURU SCHOOL OF DENTISTRY, UNIVERSITY OF SÃO PAULO, DEPARTMENT OF STOMATOLOGY, AREA OF PATHOLOGY. Man, 23, had a unilocular radiolucent lesion extending from the lower second premolar to the ramus of the mandibule that involved the impacted third molar. After excisional biopsy, the denitive diagnosis was unicystic ameloblastoma with luminal and mural tumor growth. The epithelial component showed frequent squamous metaplasia, resulting in an acanthomatous pattern, as well as other histological variants, including basal cell and granular cell types. There were also hyaline ring granulomas in the brous wall. This granuloma has been described under various names, such as pulse granuloma and oral vegetable granuloma. Hyaline ring granuloma is a rare oral lesion with a controversial etiology that is characterized by the presence of rings of palely eosinophilic structureless material with foreign body type multinucleated giant cells around and within the rings. Occasionally the lesions occur in the wall of inammatory odontogenic cysts. No other report doc- uments their presence in unicystic ameloblastoma. PE-328 - UNUSUAL PRESENTATION OF THE ODON- TOGENIC KERATOCYST WITH EXTENSIVE CALCIFIED AREAS. CYNTIA HELENA PEREIRA DE CARVALHO, CASSIANO FRANCISCO WEEGE NONAKA, ANA RAFAELA LUZ DE AQUINO, BRUNA AGUIAR DO AMARAL, JOSÉ IVO QUEIROZ AMARAL, LÉLIA BATISTA DE SOUZA, LEÃO PEREIRA PINTO. UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE. Odontogenic keratocyst (OKC) is a locally aggressive odontogenic lesion lined by parakeratinized stratied squamous epithelium. Foci of calcication in the brous capsule of OKC have been reported previously, but are considered rare. Woman, 25, had an OKC in the right posterior maxilla. Panoramic ra- diographs revealed a unilocular radiolucency involving unerupted permanent tooth #18 and extending to the maxillary sinus. Computed tomography showed a hypodense lesion circumscribed by a hyperdense halo and content consisting of uid material and calcications. Based on a suspected diagnosis of calcifying cystic odontogenic tumor, incisional biopsy was performed. Micro- scopic examination revealed a cystic cavity lined by parakerati- nized stratied squamous epithelium with a corrugated surface. In areas of the brous wall, scattered irregular eosinophilic masses, dystrophic calcications with circular shape, and hairpin-shaped structures were found. With the denitive diagnosis of OKC, total enucleation of the lesion was performed. The patient remains under follow-up. PE-329 - USE OF TOOLS TO IMPROVE REFERRAL PRO- CESS BETWEEN PRIMARY AND SPECIALTY CARE IN ORAL MEDICINE. CAROLINE ZIMMERMANN, MARIA INÊS MEURER, FERNANDA DA SILVA DO NASCIMENTO, JOSIMARI TELINO DE LACERDA, LILIANE JANETE GRANDO. UNIVERSIDADE FEDERAL DE SANTA CATARINA. In Brazil, the Public Health System is deploying an online in- formation system to schedule consultations. A regulatory system sets the schedule depending on the urgency of the health problem as conveyed by the clinical description. In Florianópolis, SC, insuf- cient descriptions of oral lesions have been identied as the greatest problem in determining care priorities. Communication is essential to the referral process, and failures can delay diagnoses and increase health care costs. Tools to guide health professionals to write referral letters can be useful to improve communication. This study evalu- ated the self-assessments of 32 dentists and 64 students of dentistry regarding their ability to describe oral lesions with no guide (freedescription) and supported by two different guide tools. Describing oral lesions using guide tools improves competence, ease, and agility during the process. The most detailed guide was considered the more effective support to fullling this task. PE-330 - VERRUCIFORM XANTHOMA OF THE PALATE: CASE REPORT. ANA PAULA MOLINA VIVAS, GUSTAVO HENRIQUE CAMPOS RODRIGUES, GABRIELA SANCHEZ NAGATA, ALEXANDER KRAUL SCARPATI, CELSO AUGUSTO LEMOS JÚNIOR, MARÍLIA TRIERVEILER MARTINS, FÁBIO DE ABREU ALVES. FOUSP. Verruciform xanthoma is an uncommon benign lesion of unknown etiology that mainly affects the oral mucosa. Clinically, this painless plaque has a papillary or verrucous surface. Man, 52, was referred for evaluation of an asymptomatic lesion on the palate. The lesion had appeared 6 years earlier, but had never been treated. Intraoral examination showed a 0.8-cm, well- demarcated, rounded whitish plaque with a verrucous surface and reddish background on the left side of the hard palate. The patient denied prior local trauma and reported tobacco use. Papilloma was the presumptive clinical diagnosis and an excisional biopsy was performed. Histopathological analysis revealed papillary epithelial hyperplasia and foamy macrophages in the lamina propria papillary zone. After 1 month of follow-up there is no sign of recurrence. The histopathological characterization of verruciform xanthoma is essential for the diagnosis, which clin- ically is often mistaken for a papilloma, condyloma, or wart. PE-331 - IMMUNOEXPRESSION OF TRANSFORMING GROWTH FACTOR BETA (TGF-ß) AND INTERLEUKIN-6 (IL-6) IN ORAL LICHEN PLANUS. THÂMARA MANOELA MARINHO BEZERRA, MÁRCIA CRISTINA DA COSTA OOOO ABSTRACTS Volume 117, Number 2 Abstracts e195

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Page 1: Unicystic Ameloblastoma With Diverse Histological Variants And Hyaline Ring Granulomas

OOOO ABSTRACTS

Volume 117, Number 2 Abstracts e195

FERNANDA GONÇALVES SALUM, KAREN CHERUBINI,VINICIUS DUVAL DA SILVA, MARIA ANTONIAZANCANARO DE FIGUEIREDO. PONTIFICAL CATH-OLIC UNIVERSITY OF RIO GRANDE DO SUL.

Woman, 22, was referred to a specialized service with allegedgum injury that had developed over 7 days. She also reporteddiscomfort, pressure, fever, and facial asymmetry. Intraoral exami-nation detected a firm nodule at the buccal aspect of the rightmandibular region that was attached to the bony tissues and wasreddish purple. It was covered by ulcerated mucosa and measured2 cm in diameter. Imaging studies revealed a radiolucent lesioninvolving the first and second premolars with disruption of corticalbone and bony crest. Incisional biopsy was performed. Histopath-ological and immunohistochemical findings were consistent withundifferentiated high-grade sarcoma. Due to the aggressiveness ofthe disease, the treatment of choice was hemimandibulectomy fol-lowed by mandibular reconstruction, neck dissection, and chemo-therapy. Subsequently, the patient suffered complications andpostponed aesthetic surgical interventions. During clinical follow-up for 10 months no signs of recurrence developed.

PE-327 - UNICYSTIC AMELOBLASTOMA WITHDIVERSE HISTOLOGICAL VARIANTS AND HYALINERING GRANULOMAS. JOSÉ BURGOS PONCE, HELITONGUSTAVO DE LIMA, TAIANE PRISCILA GARDIZANI,MOACYR TADEU VICENTE RODRIGUES, RODRIGOQUEIROZ ALEIXO, FABRICIO GUIMARÃES DE SOUZA,VANESSA SOARES LARA. BAURU SCHOOL OFDENTISTRY, UNIVERSITY OF SÃO PAULO, DEPARTMENTOF STOMATOLOGY, AREA OF PATHOLOGY.

Man, 23, had a unilocular radiolucent lesion extending fromthe lower second premolar to the ramus of the mandibule thatinvolved the impacted third molar. After excisional biopsy, thedefinitive diagnosis was unicystic ameloblastoma with luminal andmural tumor growth. The epithelial component showed frequentsquamous metaplasia, resulting in an acanthomatous pattern, aswell as other histological variants, including basal cell and granularcell types. There were also hyaline ring granulomas in the fibrouswall. This granuloma has been described under various names,such as pulse granuloma and oral vegetable granuloma. Hyalinering granuloma is a rare oral lesion with a controversial etiologythat is characterized by the presence of rings of palely eosinophilicstructureless material with foreign body�type multinucleated giantcells around and within the rings. Occasionally the lesions occur inthe wall of inflammatory odontogenic cysts. No other report doc-uments their presence in unicystic ameloblastoma.

PE-328 - UNUSUAL PRESENTATION OF THE ODON-TOGENIC KERATOCYST WITH EXTENSIVE CALCIFIEDAREAS. CYNTIA HELENA PEREIRA DE CARVALHO,CASSIANO FRANCISCO WEEGE NONAKA, ANARAFAELA LUZ DE AQUINO, BRUNA AGUIAR DOAMARAL, JOSÉ IVO QUEIROZ AMARAL, LÉLIA BATISTADE SOUZA, LEÃO PEREIRA PINTO. UNIVERSIDADEFEDERAL DO RIO GRANDE DO NORTE.

Odontogenic keratocyst (OKC) is a locally aggressiveodontogenic lesion lined by parakeratinized stratified squamousepithelium. Foci of calcification in the fibrous capsule of OKChave been reported previously, but are considered rare. Woman,25, had an OKC in the right posterior maxilla. Panoramic ra-diographs revealed a unilocular radiolucency involving uneruptedpermanent tooth #18 and extending to the maxillary sinus.

Computed tomography showed a hypodense lesion circumscribedby a hyperdense halo and content consisting of fluid material andcalcifications. Based on a suspected diagnosis of calcifying cysticodontogenic tumor, incisional biopsy was performed. Micro-scopic examination revealed a cystic cavity lined by parakerati-nized stratified squamous epithelium with a corrugated surface. Inareas of the fibrous wall, scattered irregular eosinophilic masses,dystrophic calcifications with circular shape, and hairpin-shapedstructures were found. With the definitive diagnosis of OKC, totalenucleation of the lesion was performed. The patient remainsunder follow-up.

PE-329 - USE OF TOOLS TO IMPROVE REFERRAL PRO-CESS BETWEEN PRIMARY AND SPECIALTY CARE INORAL MEDICINE. CAROLINE ZIMMERMANN, MARIAINÊS MEURER, FERNANDA DA SILVA DO NASCIMENTO,JOSIMARI TELINO DE LACERDA, LILIANE JANETEGRANDO. UNIVERSIDADE FEDERAL DE SANTACATARINA.

In Brazil, the Public Health System is deploying an online in-formation system to schedule consultations. A regulatory systemsets the schedule depending on the urgency of the health problem asconveyed by the clinical description. In Florianópolis, SC, insuffi-cient descriptions of oral lesions have been identified as the greatestproblem in determining care priorities. Communication is essentialto the referral process, and failures can delay diagnoses and increasehealth care costs. Tools to guide health professionals to write referralletters can be useful to improve communication. This study evalu-ated the self-assessments of 32 dentists and 64 students of dentistryregarding their ability to describe oral lesions with no guide (“free”description) and supported by two different guide tools. Describingoral lesions using guide tools improves competence, ease, andagility during the process. The most detailed guide was consideredthe more effective support to fulfilling this task.

PE-330 - VERRUCIFORM XANTHOMA OF THE PALATE:CASE REPORT. ANA PAULA MOLINA VIVAS, GUSTAVOHENRIQUE CAMPOS RODRIGUES, GABRIELA SANCHEZNAGATA, ALEXANDER KRAUL SCARPATI, CELSOAUGUSTO LEMOS JÚNIOR, MARÍLIA TRIERVEILERMARTINS, FÁBIO DE ABREU ALVES. FOUSP.

Verruciform xanthoma is an uncommon benign lesion ofunknown etiology that mainly affects the oral mucosa. Clinically,this painless plaque has a papillary or verrucous surface. Man, 52,was referred for evaluation of an asymptomatic lesion on thepalate. The lesion had appeared 6 years earlier, but had neverbeen treated. Intraoral examination showed a 0.8-cm, well-demarcated, rounded whitish plaque with a verrucous surface andreddish background on the left side of the hard palate. The patientdenied prior local trauma and reported tobacco use. Papillomawas the presumptive clinical diagnosis and an excisional biopsywas performed. Histopathological analysis revealed papillaryepithelial hyperplasia and foamy macrophages in the laminapropria papillary zone. After 1 month of follow-up there is nosign of recurrence. The histopathological characterization ofverruciform xanthoma is essential for the diagnosis, which clin-ically is often mistaken for a papilloma, condyloma, or wart.

PE-331 - IMMUNOEXPRESSION OF TRANSFORMINGGROWTH FACTOR BETA (TGF-ß) AND INTERLEUKIN-6(IL-6) IN ORAL LICHEN PLANUS. THÂMARA MANOELAMARINHO BEZERRA, MÁRCIA CRISTINA DA COSTA