uncovering the basis of a severe degree of acidemia in a patient with diabetic ketoacidosis by m....
TRANSCRIPT
Uncovering the basis of a severe degree of acidemia in a patient with diabetic ketoacidosis
by M. Gowrishankar, A.P.C.P. Carlotti, C. St George-Hyslop, D. Bohn, K.S. Kamel, M.R. Davids, and M.L. Halperin
QJMVolume 100(11):721-735
October 30, 2007
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Overview of the biochemistry and physiology of ketoacidosis.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Uncoupling of oxidative phosphorylation and hepatic ketogenesis.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Balance for H+ and β-HB− when ketoacids are accumulating.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Indirect loss of NaHCO3.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Buffering of H+ in the brain in a patient with a contracted ‘effective’ arterial blood volume.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]
Time course for the rise in the PHCO3 in this patient.
M. Gowrishankar et al. QJM 2007;100:721-735
© The Author 2007. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: [email protected]