• Free, open source, on-line broswer for genomes
• Contains ~100 genomes, from nematodes to human.
• Many tools that can be used to analyze genomic data
Genome browser
How to find a gene of interest?
Lets take a look at the gene
Sequences +Links to other
databases
Information about the gene
mRNA length
Protein sequence,mRNA sequence
Zooming in can help us identifying alternative splicing events
How to download a gene sequence?
Different parts of the gene
1. In which chromosome can you find the CFTR gene in human?
2. In which chromosome can you find the CFTR gene in mouse?
3. How many exons does the CFTR gene have?
4. Suggest a way to discover exons without searching for mRNA
5. Which animo acid(s) will join the protein if the termination codon will be mutated?
6. Which genes are close to CFTR on chromosome 7?
7. What is the orientation of the gene? Plus or minus?
8. download the promoter area of the CFTR gene (1000 bp)
9. How many polyadenylation sites are known on the CFTR gene?
10. Are there microsatellites on the CFTR gene?