tsxv:bee dr. john sutton, christoph lehnen abim

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Bee Vectoring of Biologicals is a highly effective and efficient Crop Protection Tool ABIM October, 2019 Dr. John Sutton, Christoph Lehnen TSXV:BEE 1 Nature’s Solution for Healthy Crops

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Bee Vectoring of Biologicals is a highly effective and efficient Crop Protection Tool

ABIMOctober, 2019

Dr. John Sutton, Christoph Lehnen

TSXV:BEE

1

Nature’s Solution for Healthy Crops

Tomato trial Mexico 2019

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0 DAA 14 DAA 21 DAA 28 DAA

PESINC % 80 Flowers / plot

Untreated

Serenade Max 4kg/ha

CR-7 3x10^6 CFU/gvect

CR-7 3x10^7 CFU/gvect

CR-7 3x10^8 CFU/gvect

CR-7 3x10^7 CFU/gsprayed (1 g/L ofwater)

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PESSEV % 80 Flowers / plotUntreated

Serenade Max 4kg/ha

CR-7 3x10^6 CFU/gvect

CR-7 3x10^7 CFU/gvect

CR-7 3x10^8 CFU/gvect

CR-7 3x10^7 CFU/gsprayed (1 g/L ofwater)

STRICTLY CONFIDENTIAL 2

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25/02/2019 09/03/2019 21/03/2019 30/03/2019 05/04/2019 16/04/2019

% fruit with fruit rot / 50 plants

Untreated Fungicide BVT-CR7 BVT-CR7 + Fungicide

BVT-CR-7 vectored by bees (tomato trial Italy 2019): good control of Botrytis = useful instrument for IPM

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BVT-CR7 BVT-CR7 + Fungicide

© BVT International Inc.

Different letters (a,b,c) = significant difference

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Number of fruit with fruit rot

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Performance of BVT System: excellent reduction of Botrytis on fruit and enhancement of yield

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Yield

Yield fresh fruit in Kg

Untreated Fungicide CR-7 CR-7 + Fungicide

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© BVT International Inc.

Tomato trial Italy 2017

Tomato trial 2018 (Greenhouse – Switzerland)Bumble bee vectoring

STRICTLY CONFIDENTIAL 5

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% Incidence of Botrytis in new stem wounds(Regular Tomato variety)

UTC BVT-CR-7

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* = significantly different

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% Incidence of Botrytis in new stem wounds (Cherry Tomato variety)

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© BVT International

Tomato trial 2018 (Greenhouse – Switzerland)Bumble bee vectoring

STRICTLY CONFIDENTIAL 6

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% fruit with disease symptoms after 10 days storage at 10-12°C (variety DR564)

Cherry Tomato – Post harvestRegular Tomato – Post harvest

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UTC BVT-CR-7

% Severity (Regular tomato variety)

Incidence: all tomatoes in UTCand BVT-CR-7 showed symptomsafter 10 days storage

© BVT International

BVT-CR-7 vectored by bumble bees: equivalent control of Botrytis on strawberries

3.8%

0.5%0.7% 0.6%

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Untreated Check Standard FungicideProgram

BVT Vectorite withCR7

BVT Vectorite withCR7 + Fungicide

Program

% Botrytis on fruitAverage visual assessment of Botrytis incidence over 13 harvests

© BVT International

BVT-CR-7 vectored by bees: enhancing yield in strawberries

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Untreated Check Standard FungicideProgram

BVT Vectorite with CR7 BVT Vectorite with CR7+ Fungicide Program

marketable yield/ ha after 13 pickings

© BVT International

Strawberry- Storage (rating during 4 consecutive days)enhancing shelf life

State University of Florida

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Fungicide program BVT Vectorite +CR7

BVT Vectorite +CR7 & Fungicide

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© BVT International

Uses of Clonostachys rosea

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❖ Bee Vectoring – Delivery to crops via managed pollinator colonies for targeted control of necrotrophic diseases

❖ Botrytis, Sclerotinia, Monilinia

❖ Foliar spray – Formulations for conventional application methods for broad bio-fungicidal use

❖ MRL exempt (residue-free), resistance management, 0-day pre-harvest interval, no re-entry interval

❖ Endophyte

❖ Seed treatment and root disease control – Formulation for seed coatings for plant growth promotion and root disease control

❖ Endophyte

❖ Early emergence; plant vigor

C.rosea is effective against the following diseases:

▪ Botrytis – Gray Mold

▪ Sclerotinia- white mold

▪ Monilinia- brown rot

▪ Rhizopus- red leak

▪ Alternaria- early blight

▪ Phomopsis

▪ Anthracnose

And more…

Focus of BVT

Exploited via Third Parties

© BVT International

2 delivery Systems To Meet Unique Grower and Crop Needs

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Bumblebee hive lid designed to incorporate dispenser tray

Removable tray with VectoriteTM

powder and plant treatment agent

Bees walk across the tray, pick up plant treatment, exit hive, and deliver it to the plant

Bumble bees, with current channel of distribution -mostly indoors Honeybees, all outdoors larger crops

-4-

❖ Larger insects with greater carrying capacity

❖ Generally better fliers in cold/damp weather

❖ Existing market structure (commercial bumble bee production)

❖ Simpler “passive” mechanical system

❖ Much larger hives (20,000 vs 300)

❖ Greater coverage (acres) per hive

❖ Electro-mechanical system; could include hive health monitoring

❖ 4.2 million hives in USA alone

Where from here: extending to biologicals and bioagents for other targets

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CR-7 Compatibility

Product CR-7 Recoverability (%)Compatibility level

Water Control 0

BVT CR-7 Spray 83

F1 17 low

B1 33 moderate

F2 50 moderate

F3 100 high

F4a 83 high

F4b 67 high

B2 50 moderate

F = Fungus; B = Bacteria

1.0E+00

1.0E+01

1.0E+02

1.0E+03

1.0E+04

1.0E+05

1.0E+06

1.0E+07

F1 B1 F2 F3 F4 B2 CR-7*

AVG CFU/bee

Ag-Biologicals: A major opportunity to reduce Chemicals

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Market Drivers Favor Ag-Biologicals

✓ Growers need higher yields

✓ New sustainable tools

✓ Reductions in chemicals

✓ Increasing regulatory hurdles (new chemical pesticide can cost $500million to develop)

✓ Consumer demand for “Safe” food with no residues

✓ Food Chain / Retailers need transparency

On Farm

Beyond Farm

$50BN Chemical Pesticide Industry Being Eroded and Replaced by Ag-Biologicals

Benefits of Ag-Biologicals

✓ No chemical residues

▪ Meets global trade needs and secondary standards of retailers

✓ Enhance yield and quality

▪ Improved plant vigor; help manage biotic and abiotic stresses

✓ Resistance management

▪ New modes of action minimize development of resistance

✓ Inherently less toxic than conventional pesticides

▪ Short re-entry and post harvest intervals gives flexibility

BVT: A Novel Disruptive Crop Production Tool

14All-Natural System: Pollination + Crop Protection + Crop Enhancement

Higher yields

Better quality Longer

shelf-life

Better Crops

Less chemicals

Less waterLess machinery

Reduced Impact

BVT System

An Alternative to Chemicals

An Alternative to Spraying

Savings:❑Water: 2500 – 5000 liters + per hectare❑Diesel: 10 – 20 liters or more per hectare

Bee Vectoring: A great Alternative to Spraying

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Rationale for Vectoring:

❖ Same principles as natural pollination

❖ The flower is the primary portal of entry for many diseases & insects

❖ Flowers are the best place for the active ingredient to inoculate the plant

Benefits of Vectoring:

❖ Substantially minimizes waste of control agent; no water

❖ Continual delivery throughout the bloom period (spraying can miss blooms)

❖ Additional yield, residue & quality benefits from improved pollination

Bee Vectoring: Use of commercial bees to deliver natural control agents to flowering crops to manage key crop diseases and pests and enhance quality and yields of crops

115 crops worldwide; 85 require pollination

Bees contribute to 1/3 of food in human diet

80+ million honey beehives globally; 5 million bumblebee hives grown every year

Confluence of Pressures to Sustainably Feed the World

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World population ~10bill by 2050

Crop productivity needs to Double

Consumers are looking for safe, healthy food

with less chemicals

Use of chemicals being limited or banned

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2015 2020 2025

Global Ag-Biologicals Market ($ Bil l)

Growers are using Ag-Biologicals* at a growing rate at expense of current $50 Billion pesticide industry

* Products derived from natural sources used to increased crop productivity

Growth in Use of Ag-Biologicals*

Bee Vectoring Technologies

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Founded in 2012 to pioneer disruptive sustainable crop production tools

▪ Use commercial bees to deliver plant treatment agents to crops

▪ System developed and optimized over 20+ years

▪ 60+ patent applications worldwide (40+ granted, 20+ pending, in 37 key countries ) in 5 technology areas

Superior Value Proposition

▪ Biopesticide controls key diseases, therefore less chemicals, sustainable crops, more profits for farmers

▪ Field trials and grower demos consistently showing higher yields, beating chemicals

▪ 100% natural (no synthetic or genetic changes) beneficial system that reduces impact on environment

BVT Today

▪ In rapid commercialization phase: regulatory process completed; year over year demos & trials with exceptional results completed; customers seeking BVT out

▪ Building partnerships with global agri-businesses

▪ Proven exceptional technology production facility can support > $20+Mill annual sales; easy to expand

Mission: To integrate innovative technologies to produce healthy food with environmentally-responsible practices that improve grower profits, benefit human consumption, and safeguard the Earth by protecting crops in the most efficient and targeted way.

Thanks / Contact Details

18

✓ Bumble and honeybees effectively deliver bioagents to the flowers in crops

✓ The BVT System is a sustainable and disruptive crop production tool

✓ Proven to manage Botrytis and improve shelf life; increase yields; enhance crops

✓ Highly suitable for IPM

✓ Proprietary system – simple and effective✓ Platform that is scalable

Contact Info

Bee Vectoring Technologywww.beevt.com

Toronto TSX.V: BEE.VUS OTC: BEVVFFrankfurt Börse: 1UR1

General: [email protected]: [email protected]

Christoph LehnenR&D [email protected]

© BVT International Inc.