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6/24/2014 Truetest

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Dealing with ContactDermatitis

Allergen Components(Found in)

Patch Testing

Interpretation of Patch TestResults

Allergen Components (Found In)

1. Nickel sulphate

Concentration: 0.20 mg/cm

Allergen component per patch: Nickel, 0.036 mg

Vehicle: Hydroxypropyl cellulose

Other substances to which thepatient may react:

Cobalt, chromium, disulfiram

Found in: Jewelry, metal, and metal-plated objects;occasionally in eye cosmetics

2. Wool alcohols (lanolin)


Allergen component per patch: Cholesterol, lanosterol, agnosterol (and dihydroderivatives); straight- and branched-chain aliphaticalcohols; 0.81 mg total (the active allergeniccomponent has not been identified)

Vehicle: Polyvidone

Synonyms and/orcomponents:

Lanolin, anhydrous lanolin, wool fat, wool wax,wool grease, ClearlinTM, GlossylanTM, GoldenDawn, HycholTM, NodorianTM, SparklelanTM,adeps lanae anhydrous, aloholes lanaeAlso modified lanolins, such as lanolin aid, lanolinalcohol, lanolin oil, lanolin wax, Amerchol L-101,and Amerchol CAB


Eucerin, Aquaphor

Found in: Cosmetics, soaps, and topical medications

3. Neomycin sulphate


Allergen component per patch: Neomycin sulfate, USP, 0.19 mg

Vehicle: Methylcellulose


Gentamicin sulfate, bacitracin, kanamycin,streptomycin sulfate injection, spectinomycin HCl,tobramycin sulfate

Found in: Topical antibiotics

4. Potassium dichromate


Allergen component per patch: Chromium, 0.0067 mg

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6/24/2014 Truetest




Chromium, chrome, chromate, chromite

Found in: Cement, chrome-tanned leather, welding fumes,cutting oils, antirust paints, other industrialchemicals

5. Caine mix


Allergen component per patch: Benzocaine, USP, 0.364 mg; tetracaine HCl,USP, 0.063 mg; dibucaine HCl, USP, 0.064 mg

Vehicle: Polyvidone


Benzocaine: ethyl aminobenzoate, p-aminobenzoic, acid (PABA) ethyl ester,Aethoform, Americaine, Anesthesin,Anesthane, Orthesin, Parathesin,Anesthone

Tetracaine HCl: tetracaine, Pontocaine

Dibucaine HCl: dibucaine, Nupercaine


Benzoic acid derivatives:PABA esters: procaine, benoxinate HCl,butamben picrate, butacaine, butethamine HCl,naepaine, orthocaine, propoxycaine, risocaine,chloroprocaine HCl m-Aminobenzoic acid esters: metabutethamine,proparacaine Benzoic acid esters: cocaine HCl, amylocaine,benzamine, cyclomethycaine, meprylcaine HCl,metabutozycaine, piperocaine HCl, hexylcaineHCl, proparacaine HCl Other agents: Procainamide, hydrochlorothiazide,PABA and PABA ester sunscreens, Azo andaniline dyes, p-phenylenediamine, sulfonamides,sulfonylureas, p-aminosalicylic acid

Found in: Topical anesthetics

6. Fragrance mix


Allergen component per patch: Geraniol, 0.070 mg; cinnamaldehyde, 0.034 mg;hydroxycitronellal, 0.054 mg; cinnamyl alcohol,0.054 mg; eugenol, 0.034 mg; isoeugenol, 0.015mg; amylcinnamaldehyde, 0.015 mg; oak moss,0.070 mg

Vehicle: Hydroxypropyl cellulose, cyclodextrin


Synonyms: cologne, toilet water, perfume,masking or unscented perfume or fragrance,aroma chemicals, essential oils of plants andanimals. Individual fragrance allergens: cinnamic alcohol,

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cinnamic aldehyde, oak moss absolute,amylcinnamic alcohol, anisyl alcohol, benzylalcohol, benzyl salicylate, coumarin, sandalwoodoil, musk ambrette, wood tars


Balsam of Peru, ethylene bassylate (Musk T),cloves, cinnamon, cassia oil, citronella candles

Found in: Fragrances, toiletries, scented householdproducts, flavorings, food, industrial products

7. Colophony


Allergen component per patch: Colophony, 0.69 mg

Vehicle: Polyvidone


Rosin, resina terebinthinae, gum rosin, rosin gum,W-W wood rosin, tall oil, abietic acid, methylabietate alcohol, abietic alcohol, abietyl alcohol,Dertomal 18, Abitol, Hercolyn D, Foral105, Staybelite 10, Granolite SG, DercolyteZS, Dertophene 18


Wood tars, other coniferous trees, other plantmaterials including Chrysanthemum, somespices, fragrances, oils

Found in: Cosmetics, adhesives, a variety of household andindustrial products

8. Epoxy resin


Allergen component per patch: Diglycidylether of bisphenol A, 0.032 mg



4,4'-Isopropylidenediphenol-epichlorohydrin,diglycidyl ether, bisphenol A [2,2-bis(4-hydroxyphenyl)propane] (diphenylpropane),epichlorohydrin (1-chloro-2,3-epoxypropane) (8-chloropropylene oxide)


The hardening agent of a two-part adhesive,specifically components such as ethylenediamine

Found in: Two-part adhesives, surface coatings, paints

9. Quinoline mix


Allergen component per patch: Clioquinol: 0.077 mg, Clorquinaldol: 0.077 mg

Vehicle: Polyvidone


5-chloro-7-iodo-8-hydroxyquinoline5,7-dichloro-8-2-methylquinoline


Vioform, chlorquinaldol quinoform, entroquinol,sterosan, quinaband, iodinechloridequinoline.Enterovioform (R)

Found in: Paste bandages, medicated creams and oinments

6/24/2014 Truetest


10. Balsam of Peru


Allergen component per patch: Balsam of Peru, 0.65 mg total

Vehicle: Polyvidone


Synonyms: balsamum peruvianim, Peruvianbalsam, Indian balsam, China oil, black balsam,Honduras balsam, Surinam balsam Components or chemically related allergens:Cinnamic acid, benzyl salicylate, vanillin, benzoicalcohol, benzyl acetate, benzaldehyde, benzylbenzoate and other benzoates, benzoic acid,cinnamic alcohol, cinnamic aldehyde, cinnamylcinnamate, methylcinnamate, eugenol,isoeugenol, coniferyl alcohols, resinoussubstances.


Cinnamein (essential oil), oil of cinnamon, tinctureof krameria, balsam of Copaiba, storax (styrax),essence of orange peel, spices (e.g., Jamaicanpepper, cinnamon, cloves, nutmeg, paprika, curry,vanilla), Tiger Balm (oriental), benzoin tincture(gum benzoin), wood tars, colophony, balsam ofTolu, turpentine, beeswax, coumarin,diethylstilbestrol, propolis

Found in: Foods, cosmetics, fragrances, flavorings, topicalmedications

11. Ethylenediamine dihydrochloride


Allergen component per patch: Ethylenediamine, 0.018 mg

Vehicle: Methylcellulose


1,2-Ethanediamine, 1,2-diaminoethane,chlorethamine


Aminophylline, hydroxyzine, piperazine-basedantihistamines (meclizine, buclizine,chlorcyclizine, cyclizine), tripelennamine,promethazine HCl, epoxy resin catalysts(ethylenediamine and chemically related aminessuch as diethylenediamine, dipropylenetriamine,triethylenetetramine, tetraethylenetetramine,trimethylhexamethylenediamine)

Found in: Topical medications, eyedrops, industrial solvents,anticorrosive agents

12. Cobalt dichloride


Allergen component per patch: Cobalt, 0.0040 mg


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Cobalt blue, cobaltous (modifying any word)

Alloys containing cobalt: Stellite, Vitallium, Alnico, Durlium,Mobilium, Permalloy, Ticonium, Wolframcarbide


Nickel, chromate

Found in: Metal-plated objects, paints, cement, vitamin B12

13. p-tert-butylphenol formaldehyde resin


Allergen component per patch: p-tert-Butylphenol formaldehyde, 0.041 mg



Paratertiary butylphenol formaldehyde resin, PTBPformaldehyde, butylphen, 4(1,1-dimethylethyl)phenol


Degaplast glue, neoprene adhesives

Found in: Waterproof glues, bonded leather, constructionmaterials, paper, fabrics

14. Paraben mix


Allergen component per patch: Methyl p-hydroxybenzoate, 0.162 mg;ethyl p-hydroxybenzoate, 0.162 mg;propyl p-hydroxybenzoate, 0.162 mg;butyl p-hydroxybenzoate, 0.162 mg;benzyl p-hydroxybenzoate, 0.162 mg;

Vehicle: Polyvidone


Methylparaben, ethylparaben, propylparaben,butylparaben, p-hydroxybenzoate, p-hydroxybenzoic acid, Nipagin, Perservaben,Protaben, Aseptoform, Lexgard, Parasept,Liqua Par, Germaben II (mixture), Nipastat(mixture), Phenonip (mixture), undebenzofene-C(mixture)


p-Aminobenzoic acid (PABA) esters, p-phenylenediamine (rarely)

Found in: Preservative in topical formulations, cosmetics,foods, industrial preparations

15. Carba mix


Allergen component per patch: Diphenylguanidine, 0.067 mg;zincdibutyldithiocarbamate, 0.067 mg;zincdiethyldithiocarbamate, 0.067 mg;


6/24/2014 Truetest



Carbamate, carbanilate, 1,3-diphenylguanidine/(DPG, Nocceler D,Sanceler D, Soxinol D),zincdibutyldithiocarbamate (ZBC, butazin, butylzimate, Nocceler BZ, Soxinol BZ, Butazate,Butasan), zincdiethyldithiocarbamate (ZDC,ZDEC, Etazin, Ethasan, ethyl zimate,Nocceler EZ, Soxinol EZ, Ethazate)


Thiuram mix, mercapto mix,mercaptobenzothiazole, disulfiram (Antabuse).

Found in: Rubber products, glues for leather, pesticides,vinyl, soaps, shampoos, disinfectants

16. Black rubber mix


Allergen component per patch: N-Isopropyl-N'-phenyl paraphenylenediamine,0.0102 mg; N-cyclohexyl-N'-phenylparaphenylenediamine, 0.0255 mg; N,N'-diphenylparaphenylene-diamine, 0.0255 mg

Vehicle: Polyvidone


N-Phenyl-N'-cyclohexyl-p-phenylenediamine(CPPD): phenylcyclohexyl PPD, Flexzone GH N-Isopropyl-N'-phenyl-p-phenylenediamine (IPPD):isopropyl 0 PPD, Akrochem Antioxidant PD1,ANTO'H', Flexzone 3-C, Permanex IPPD,Santoflex IP N,N'-Diphenyl-p-phenylenediamine (DPPD):Diphenyl PPD


Hair dye chemicals: p-aminodiphenylamine, p-phenylenediamine

Found in: All black rubber products, some hair dyes

17. Cl+ Me- Isothiazolinone


Allergen component per patch: 5-Chloro-2-methyl-4-isothiazolin-3-one, 0.0024 mg;2-methyl-4-isothiazolin-3-one, 0.0008 mg

Vehicle: Polyvidone


Methylchloroisothiazolinone (MCI),methylisothiazolinone (MI), Kathon


Other isothiazolinones

Found in: Cosmetics and skin care products, topicalmedications, household cleaning products; asKathon in industrial products

18. Quaternium-15


6/24/2014 Truetest


Allergen component per patch: Quaternium-15, 0.081 mg



N-(3-chloroallyl)-Hexaminium chloride, cis-1-(3-chloroallyl)-3,5,7-triaza-1-azonium-adamantanechloride, 1-(3-chloroallyl)-3,5,7-triaza-1-azonium-adamantane chloride, Preventol D 1,methanamine-3-chloroallylochloride, chloroallylmethanamine chloride, Dowicil 75 (or 100 or200), azonium-adamantane chloride


Formaldehyde:Formaldehyde-releasing preservatives found incosmetics and topical agents: Germall 115(imidazolidinyl urea), Germall II (diazolidinylurea), Glydant [DMDM (dimethylolmethyl)hydantoin], Bronopol (2-bromo-2-nitropropane-1,3-diol), Tris Nitro [tris (hydroxymethyl)nitromethane] Formaldehyde-releasing preservatives found inindustrial and metal-working fluids: Dowicil 75,Tris Nitro, Grotan HD2, Grotan BK,Triadine-10, Onyxide 200, Vancide TH,Myacide BT

Found in: preservative in cosmetics and skin care products,household polishes and cleaners, industrialproducts

19. Mercaptobenzothiazole


Allergen component per patch: Mercaptobenzothiazole, 0.061 mg

Vehicle: Polyvidone


MBT, 2-benzathiazalethiol, Captax, Dermacid,Mertax, Thiotax, Nocceler M, Rotax


Mercapto mix, thiuram mix, carba mix

Found in: Rubber products, adhesives, industrial products,veterinary tick/flea sprays and powders, filmemulsion

20. p-Phenylenediamine


Allergen component per patch: p-Phenylenediamine, 0.073 mg

Vehicle: Polyvidone


Paraphenylenediamine (PPD or PPDA), 1,4-benzenediamine, 1,4-phenylenediamine, RodolD, p-aminoaniline, Orsin, p-diaminobenzene,Ursol D


PABA-based sunscreens or creams, other dyechemicals, Azo or disperse textile dyes, p-aminosalicylic acid, black rubber products,

6/24/2014 Truetest


diaminodiphenylmethane (epoxy hardener), p-toluenediamine, p-aminodiphenylamine, 2,4-diaminoanisole, o-animophenolOccasionally, 'sulfa' drugs (sulfonamides), 'caine'drugs such as benzocaine

Found in: Permanent (coal tar) or semipermanent hair dyes,dyed textiles, cosmetics, printing ink,photodeveloper

21. Formaldehyde


Allergen component per patch: Formaldehyde, 0.15

Vehicle: Polyvidone


Oxymethylene, methanal, formalin

Formaldehyde-releasingpreservatives:

Preservatives found in cosmetics and topicalagents: Quaternium-15, Germall 115(imidazolidinyl urea), Germall II (diazolidinylurea), Glydant [DMDM(dimethylolmethyl)hydantoin], Bronopol (2-bromo-2-nitropropane-1,3-diol), Tris Nitro [tris (hydroxymethyl)nitromethane] Preservatives found in industrial and metal-workingfluids: Dowicil 75, Tris Nitro, Grotan HD2,Grotan BK, Triadine-10, Onyxide 200,Vancide TH, Myacide BT.

Found in: Fabric finishes, cosmetics, plastics, syntheticresins, glues, textiles, construction material

22. Mercapto mix


Allergen component per patch: N-Cyclohexylbenzothiazyl-sulfenamide, 0.0203mg; dibenzothiazyl disulfide, 0.0203 mg;morpholinylmercaptobenzothiazole, 0.0203 mg

Vehicle: Polyvidone


N-Cyclohexyl-2-benzothiazole-sulfenamide (CBTS,CBS): cyclohexylbenzothiazyl-sulphenamide,Durax, SantocureDibenzothiazyl disulfide: 2,2'-benzothiazyldisulfide, Altax, Thiofide, Naugex MBT,Vulkacit DMMorpholinylmercaptobenzothiazole (MOR, MMBT):4-morpholinyl-2-benzothiazyl disulfide


Mercaptobenzothiazole, carba mix, thiuram mix

Found in: Rubber products, glues for leather and plastics,industrial products

23. Thiomersal


6/24/2014 Truetest


Allergen component per patch: Thiomersal, 0.0065 mg


Synonyms and/or components: Merthiolate, Mercurochrome, sodium

ethylmercurithiosalicylate, mercurothiolate, merzonin,

mertorgan, merfamin, ethyl (2-mercaptobenzoato-S) mercury

(sodium salt), thiomersalate, thiomersal, thiomersalan, [(o-

carboxyphenyl)thio] ethylmercury (sodium salt)

Other substances to w hich the

patient may react:

Other organic (not metallic) mercury compounds, piroxicam

(Feldene)

Found in: Preservative in contact lens solutions, cosmetics, nose and

ear preparations, injectable drugs

24. Thiuram mix


Allergen component per patch: Tetramethylthiuram monosulfide, 0.0051 mg;tetramethylthiuram disulfide, 0.0051 mg;disulfiram, USP, 0.0051 mg;dipentamethylenethiuram disulfide, 0.0051 mg

Vehicle: Polyvidone


Tetramethylthiuram monosulfide (TMTM) Tetramethylthiuram disulfide (TMTD): Thiram,thiurad, Thiosan, Thylate, Thiuramyl,Tiuramyl, Puralin, Fernasan, Nomersan,Rezifilm, Pomarsal, Tersan, Tuads,Tulisan, Arasan Disulfiram: Antabuse, bis(diethylthiocarbamoyl)disulfide, tetraethylthiuram disulfide (TETD),Cronetal, Abstenisil, Stopetyl, Contralin,Robac TET, Antadix, Antiethanol, ethylthiurad, Etabus, Rosulfiram, Abstinyl,Thiuranide, Tetradine, Noxal Dipentamethylenethiuram disulfide (PTD):Robac PTD


Mercapto mix, mercaptobenzothiazole, carba mix

Found in: Rubber products, adhesives, pesticides, gloves,drugs

25. Diazolidinyl urea


Allergen component per patch: Diazolidinyl urea, 0.45 mg

Vehicle: Polyvidone


Imidazolidinyl urea (Germall 115),benzylhemiformal, Bronopol, Quarternium-15,DMDM hydantoin, trimetylolnitromethan

Found in: Cosmetics, shampoos and skin care products.Liquid soaps, hair conditioners, gels, bubblebaths, baby wipes

6/24/2014 Truetest


26. Imidazolidinyl urea


Allergen component per patch: Imidazolidinyl urea, 0.49 mg



Diazolidinyl urea (Germall II), benzylhemiformal,bromonitropropanediol, Quarternium-15, DMDMhydantoin, trimethylolnitromethan

Found in: Cosmetics, shampoos and skin care products.Liquid soaps, hair conditioners, gels, bubblebaths, baby wipes.

27. Budesonide


Allergen component per patch: Budesonide, 0.00081 mg

Vehicle: Polyvidone


Amcinonide, desonide, flucloronide, flunisolide,fluocinonide, halcinonide, procinonide,triamcinolone

Found in: In medications prescribed topically for eczemaand other local inflammations. Creams, lotions,ointments, and powders. Ear, nose and eye dropsfor rhinitis, otitis, and conjunctivitis

28. Tixocortol Pivalate


Allergen component per patch: Tixocortol Pivalate, 0.0024 mg

Vehicle: Polyvidone


Hydrocortisone, prednisolone, fludrocortisoneacetate, methylprednisolone, cloprednol

Found in: Creams, lotions, ointments, powders, ear, nodeand eye drops for the treatment of eczema andother local inflammations.

29. Hydrocortisone-17-butyrate


Allergen component per patch: Hydrocortisone-17-butyrate, 0.016 mg

Vehicle: Polyvidone


Hydrocortisone-17-aceponate, hydrocortisone-17-buteprat, methylprednisolone aceponate,prednicarbate

Found in: Ezcema medication. Creams, lotions, ointments,and powders. Ear, nose and eye drops for rhinitis,otitis, and conjunctivitis

6/24/2014 Truetest


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