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    Trigeminal Nerve:

    V1 and V2

    Trigeminal Nerve:

    V1 and V2

    Alex Forrest

    Associate Professor of Forensic OdontologyForensic Science Research & Innovation Centre, Griffith University

    Consultant Forensic Odontologist,

    Queensland Health Forensic and Scientific Services,

    39 Kessels Rd, Coopers Plains, Queensland, Australia 4108

    Oral Biology

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    COMMONWEALTH OF AUSTRALIA

    Copyright Regulations 1968

    WARNING

    This material has been reproduced and communicated to you by, or onbehalf of, Griffith University, pursuant to Part VB of The Copyright Act 1968

    (The Act; a copy of the Act is available at SCALEPlus, the legal

    information retrieval system owned by the Australian Attorney Generals

    Department, at http://scaleplus.law.gov.au).

    The material in this communication may be subject to copyright under the

    Act. Any further reproduction or communication of this material by you may

    be the subject of Copyright Protection under the Act.

    Information or excerpts from this material may be used for the purposes of

    private study, research, criticism or review as permitted under the Act, and

    may only be reproduced as permitted under the Act.

    Do not remove this notice.

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    Learning ObjectivesLearning Objectives

    1. You should be able to understand and explain the gross

    anatomy of V in detail2. You should be able to understand and explain the anatomy

    of V in both structural and functional terms, showing how

    these are correlated.

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    Learning ObjectivesLearning Objectives

    3. You should be able to understand and explain in detail the

    nerve supply of the upper and lower teeth, and the

    anatomical relations of the nerves involved.

    4. You should understand, and be able to explain, how this

    information is important in local anaesthesia in the clinical

    setting, with particular reference to accessory nervesupplies to oral structures.

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    Trigeminal NerveTrigeminal Nerve

    The trigeminal nerve, or cranial nerve number five (V), is thecranial nerve of greatest importance to the dentist.

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    Trigeminal NerveTrigeminal Nerve

    It is the sensory nerve of

    the front of the head andthe face.

    It is also the motor nerve

    that supplies motorinnervation to the

    muscles of mastication,

    the anterior belly of the

    digastric and the

    mylohyoid.

    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

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    Trigeminal NerveTrigeminal Nerve

    It provides sensory innervation to the oral cavity and to the

    dental and paradental structures.

    For this reason, it is branches of this nerve that are most

    commonly anaesthetized so that otherwise painful dental

    procedures can be performed comfortably for patients.

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

    The three peripheral

    divisions of the

    trigeminal nerve

    supply common

    sensation (touch,pressure, temperature

    and pain) to the skin of

    the front of the face

    and the scalp as farback as the vertex of

    the head.

    Cutaneous DistributionCutaneous Distribution

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

    Cutaneous DistributionCutaneous Distribution

    The ophthalmic

    division (V1) supplies

    the skin of the

    anterior portion ofthe scalp and the

    forehead, the upper

    eyelid, and the front

    of the nose as fardown as its tip.

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

    Cutaneous DistributionCutaneous Distribution

    The maxillary

    division (V2) supplies

    the skin at the side

    of the nose, the

    lower eyelid and the

    upper part of the

    cheek and upper lip.

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

    Cutaneous DistributionCutaneous Distribution

    The mandibular

    division (V3) supplies

    the chin and lower

    lip, the skin in frontof the ear, and the

    skin of the side of

    the head up to the

    area supplied by theophthalmic division.

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1106

    Cutaneous DistributionCutaneous Distribution

    The angle of themandible is not

    supplied by the

    trigeminal nerve; it,

    along with the backof the head and

    much of the neck, is

    supplied by cervical

    nerves C2 and C3.

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    Central ConnectionsCentral Connections

    The unipolarsomatic

    sensory cells of the

    trigeminal nerve do nothave their cell bodies

    located in the central

    nervous system.

    Instead, they are found in

    the trigeminal ganglion in

    the same way that the cell

    bodies of spinal somaticsensory cells are located

    in the dorsal root ganglion

    of a spinal nerve.Modified from Grays Anatomy, Longmans, London, 38th Ed 1989

    p. 1107

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    Central ConnectionsCentral Connections

    The fibres terminate

    in the only nuclei for

    general sensation inthe brainstem, the

    spinal nucleus and

    the chief sensory

    nucleus.

    Modified from Grays Anatomy, Longmans, London, 38th Ed 1989 p. 953

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    Central ConnectionsCentral Connections

    Modified from Grays Anatomy, Longmans, London, 38th Ed 1989 p. 953

    Proprioceptive fibres are

    important in various reflex

    responses involving thejaws, and because they

    need to be able to act very

    fast, these are the only

    peripheral sensory cells in

    the body whose cell bodies

    are located within the

    central nervous system.They lie in the

    mesencephalic nucleus.

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    Central ConnectionsCentral Connections

    Motor cells of the

    trigeminal nerveoriginate in the

    trigeminal motor

    nucleus.

    Modified from: From Grays Anatomy, Longman, London, 38th

    Edition, 1989. p 953.

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    The Ophthalmic Division (V1)

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    Ophthalmic Division (V1)Ophthalmic Division (V1)

    The ophthalmic division, or V1 as it is commonly known (for

    division "1" of "V", the fifth cranial nerve), is purely a sensory

    nerve. It contains no somatic motor fibres at all.

    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1101

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    V1 OriginsV1 Origins

    It originates in and

    around the orbit andforms three main

    branches, which pass

    into the cranium

    through the superior

    orbital fissure, and join

    up with each other to

    run in the lateral wallof the cavernous sinus

    with three other cranial

    nerves (III, IV and VI).Grays Anatomy, Longmans, London, 38th Ed 1989 p. 803

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    V1 BranchesV1 Branches

    There are three major peripheral branches of this nerve, and

    each of those has several further branches:

    Frontal Nerve

    Lacrimal Nerve

    Nasociliary Nerve

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    The frontal nerve runs

    across the top of the

    orbit, and as it comescloser to the face, it

    divides into two major

    branches.

    These are the

    supraorbital nerve and

    the supratrochlear

    nerves.

    Grays Anatomy, Longmans, London,

    38th Ed 1989 p. 1098

    V1 BranchesV1 Branches

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    Grays Anatomy, Longmans, London,

    38th Ed 1989 p. 1098

    The supraorbital nerve

    emerges onto the face

    through thesupraorbital foramen

    (sometimes this is just

    a notch rather than afull-blown foramen),

    and runs up onto the

    forehead to supply the

    tissues of theforehead and scalp.

    V1 BranchesV1 Branches

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    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1098

    The supratrochlear

    nerve runs more

    medially and emerges

    from the orbit close toits medial edge.

    Here it runs up to

    supply the medialportion of the upper

    eyelid and the skin of

    the forehead and scalp

    towards the medial

    aspect of the forehead

    and the skin above the

    root of the nose.

    V1 BranchesV1 Branches

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    Grays Anatomy, Longmans, London,

    38th Ed 1989 p. 1098

    The lacrimal nervesupplies the

    conjunctiva and skin of

    the lateral side of the

    upper eyelid and the

    lacrimal gland with

    common sensation.

    The secretomotor

    nerves to the lacrimal

    gland are passed to

    the lacrimal nerve fromthe maxillary division

    of the trigeminal nerve.

    V1 BranchesV1 Branches

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    Hence the statement that the ophthalmic nerve is purely a

    sensory nerve remains correct. It simply receives

    communication from another source, but the motor nerves do

    not originate with the ophthalmic nerve.

    Grays Anatomy, Longmans, London, 38th Ed 1989 p. 1100

    V1 BranchesV1 Branches

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    In fact, they do not even originate with the trigeminal nerve, but

    instead with the facial nerve (VII) via the greater superficial

    petrosal nerve and the pterygopalatine ganglion.

    This is a phenomenon to which we will become used - the

    ability of certain groups of nerve fibres to "hitch a ride" with any

    passing nerve trunk that is convenient and is heading in the

    correct direction.

    V1 BranchesV1 Branches

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    Grays Anatomy, Longmans, London,38th Ed 1989 p. 1098

    The nasociliary nerve

    supplies the more medial

    structures associated

    with the orbit.

    These include the lining

    membranes of the

    sphenoidal and ethmoidalsinuses, the tissues of

    the roof of the nose and

    the skin over the front of

    the nose down as far as

    its tip.

    V1 BranchesV1 Branches

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    You should make

    an effort to

    understand how the

    nerves that radiatefrom the orbit

    beneath the skin

    contribute to the

    pattern of

    cutaneous nerve

    sensation in the

    area supplied byV1.

    Modified from: Evers H &

    Haegerstam G. Introduction to

    Dental Local Anaesthesia.,

    Mediglobe SA, Fribourg, 2nd Ed.1990, p. 12.

    V1 BranchesV1 Branches

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    The Maxillary Division (V2)

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    The maxillarydivision of the

    trigeminal nerve,

    often known simply

    as the maxillary

    nerve, also contains

    only sensory fibres.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973

    p. 1005

    The Maxillary Division (V2)The Maxillary Division (V2)

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    The nerve originates

    from the trigeminal

    ganglion as itsintermediate branch,

    lying between those of

    V1 and V3.

    It runs forward in the

    middle cranial fossa in

    the lateral wall of the

    cavernous sinus andpasses out of the

    cranium through

    foramen rotundum. Modified from Grays Anatomy, Longmans, London, 38th Ed 1989p. 1107

    The Maxillary Division (V2)The Maxillary Division (V2)

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    Just before it runs through the foramen, it gives off a smallbranch to supply the dura mater of the middle cranial fossa.

    The Maxillary Division (V2)The Maxillary Division (V2)

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    Once it enters foramen

    rotundum, it passes

    through the bone toemerge in the

    pterygopalatine fossa.

    Illustrated Handbook in Local Anaesthesia,

    Ed: E. Eriksson, Munksgaard, Denmark,

    1969, p.66.

    The Maxillary Division (V2)The Maxillary Division (V2)

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    When it reaches the pterygopalatine fossa, it gives off a

    number of branches.

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 1006

    The Maxillary Division (V2)The Maxillary Division (V2)

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    Lying inferior to the nervetrunk is a parasympathetic

    ganglion called the

    pterygopalatine ganglion.

    Two branches from the nerve

    pass towards this, and

    subsequently continue

    through the ganglion to formfurther branches within the

    pterygopalatine fossa.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973 p. 1005

    The Maxillary Division (V2)The Maxillary Division (V2)

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    The main trunk of the nerve,

    however, continues anteriorly

    to run through the inferior

    orbital fissure (be sure youunderstand how this relates to

    the pterygopalatine fossa by

    looking at a skull), and

    changes its name to theinfraorbital nerve.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973 p. 1005

    The Maxillary Division (V2)The Maxillary Division (V2)

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    It sinks down into a depressed

    groove in the orbital surface of

    the maxilla where it often gives

    off a middle superior dental

    nerve, and this groove

    eventually roofs over to formthe infraorbital canal.

    The nerve runs through this

    canal, and eventually emerges

    on the facial surface of the

    maxilla through the infraorbital

    foramen.Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973 p. 1005

    The Maxillary Division (V2)The Maxillary Division (V2)

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    Here it gives of branches to

    the upper lip, lower eyelid

    and the side of the nose.

    In the canal, the infraorbital

    nerve gives off the smallanterior superior dental

    nerve, the nerve supply to

    the upper anterior teeth,

    running in canaliculus

    sinosus.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973 p. 1005

    The Maxillary Division (V2)The Maxillary Division (V2)

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    The branches of the maxillary nerve in the pterygopalatine

    fossa include:

    posterior superior dental nerves

    palatine nerves

    sphenopalatine nerves (nasal nerves)

    pharyngeal nerves

    zygomatic nerve

    The Maxillary Division (V2)The Maxillary Division (V2)

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    The Posterior Superior Dental NervesThe Posterior Superior Dental Nerves

    The posterior superior dentalnerve ornerves (there are

    usually several) contribute to

    the nerve supply of the upper

    teeth.

    They run downwards on the

    back of the maxilla and pass

    into the bone through aseries of small foramina.

    Modified from Grays Anatomy, Longmans,

    London, 35th Ed 1973 p. 1005

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    Here they run into the body of

    the maxilla, and reach the

    lining tissue of the maxillarysinus which they supply with

    sensory nerve endings.

    From here, the fibres aredistributed further to form the

    molar part of the nerve plexus

    that supplies the upper teeth.

    This is known as the superior

    dental nerve plexus.

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 1005

    The Posterior Superior Dental NervesThe Posterior Superior Dental Nerves

    SS

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    Small nerve twiglets are also supplied to the gingivae on the

    buccal aspect of the molar teeth, and also to the superior

    portion of the cheek in the molar area.

    Because the same nerves that supply the teeth also supply the

    maxillary sinus lining, the pain of maxillary sinusitis is often

    referred to the upper teeth, especially in the premolar area.

    The Posterior Superior Dental NervesThe Posterior Superior Dental Nerves

    Th P l ti NTh P l ti N

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    The Palatine NervesThe Palatine Nerves

    The palatine nerves, as their names imply, provide somaticsensory nerve supply to the palate, and parasympathetic

    secretomotor nerves to the minor salivary glands contained in

    the palatal mucosa.The somatic fibres originate at first in the branches of the

    maxillary nerve that extend into the pterygopalatine ganglion,

    and emerge from this without having synapsed, because they

    are somatic sensory nerve fibres which do not synapse along

    their length.

    The Palatine NervesThe Palatine Nerves

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    The Palatine NervesThe Palatine Nerves

    While the fibres that will become the palatine nerve are in theganglion however, some post-ganglionic parasympathetic

    secretomotor fibres from the ganglion get picked up and run

    with them to be distributed to the minor salivary glands. The

    nerve also contains some taste fibres.

    Modified from

    Grays

    Anatomy,

    Longmans,

    London, 35th

    Ed 1973 p.

    1006

    The Palatine NervesThe Palatine Nerves

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    The Palatine NervesThe Palatine Nerves

    Modified from

    Grays

    Anatomy,

    Longmans,

    London, 35th

    Ed 1973 p.

    1006

    Some branches of the palatine nerve emerge through thelesser palatine foramina in the palatine bones, and these are

    termed the lesser palatine nerves. They provide taste fibres,

    secretomotor fibres and common sensation to the tissues of the

    soft palate.

    The Palatine NervesThe Palatine Nerves

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    The Palatine NervesThe Palatine Nerves

    Modified from

    Grays

    Anatomy,

    Longmans,

    London, 35th

    Ed 1973 p.

    1006

    The remainder pass through the greater palatine foramen andbecome the greater palatine nerves, running forwards in the

    palate to approximately the level of the canine tooth, where they

    meet and anastomose with the fibres of the long

    sphenopalatine nerve.

    Th P l ti NTh P l ti N

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    The Palatine NervesThe Palatine Nerves

    Because the palatal tissues are supplied by these nerves, weneed to anaesthetize them if we wish to extract a palatal tooth,

    because otherwise the palatal gums will remain sensitive.

    The Sphenopalatine NerveThe Sphenopalatine Nerve

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    The Sphenopalatine NerveThe Sphenopalatine Nerve

    The sphenopalatine nerve passes medially into the

    sphenopalatine foramen, which lies in the deepest part of the

    pterygopalatine fossa.

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 1006

    The Sphenopalatine NerveThe Sphenopalatine Nerve

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    The Sphenopalatine NerveThe Sphenopalatine Nerve

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 1006

    After passing through the foramen, the nerve gives off some

    small lateral branches (short sphenopalatine nerves) which are

    distributed over most of the lateral wall of the nasal cavity.

    The Sphenopalatine NerveThe Sphenopalatine Nerve

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    The Sphenopalatine NerveThe Sphenopalatine Nerve

    The long sphenopalatine or nasopalatine nerve crosses the roof

    of the nasal cavity and descends on the nasal septum to supply

    the overlying mucous membrane.

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 997

    The Sphenopalatine NerveThe Sphenopalatine Nerve

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    The Sphenopalatine NerveThe Sphenopalatine Nerve

    The nerve continues through the incisive canal to communicate

    with the greater palatine nerves. Small twigs help to supply the

    palatine supporting structures of the central and lateral incisors.

    Modified from: Illustrated

    Handbook in Local

    Anaesthesia, Ed: E.

    Eriksson, Munksgaard,Denmark, 1969, p.66.

    The Pharyngeal NervesThe Pharyngeal Nerves

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    The Pharyngeal NervesThe Pharyngeal Nerves

    The pharyngeal nerves supply the mucous membrane of the

    upper nasopharynx.

    Modified from Grays Anatomy, Longmans, London, 35th Ed 1973 p. 1006

    The Zygomatic NerveThe Zygomatic Nerve

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    The Zygomatic NerveThe Zygomatic Nerve

    The zygomatic nerve runs

    into the orbit through the

    inferior orbital fissure like the

    infraorbital nerve, but instead

    of running across the floor of

    the orbit, it runs on the lateral

    wall on the zygomatic bone,from which it takes its name.

    It also picks up some fibres

    from the pterygopalatineganglion.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973

    p. 1005

    The Zygomatic NerveThe Zygomatic Nerve

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    The Zygomatic NerveThe Zygomatic Nerve

    It divides into two branches, the zygomaticotemporal nerve

    and the zygomaticofacial nerve which run into the zygomaticbone through two small foramina, and these emerge through

    foramina which take the names of the nerve branches.

    The Zygomatic NerveThe Zygomatic Nerve

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    The Zygomatic NerveThe Zygomatic Nerve

    The parasympathetic secretomotor fibres from thepterygopalatine ganglion travel in this branch of the nerve, and

    they run to the lacrimal nerve of V1, travelling along it to the

    lacrimal gland, and constitute most of its parasympathetic

    secretomotor innervation.

    Lacrimal Branch

    Modified from

    Grays Anatomy,

    Longmans,

    London, 35th Ed

    1973 p. 1005

    The Infraorbital NerveThe Infraorbital Nerve

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    The Infraorbital NerveThe Infraorbital Nerve

    The important

    branches of the

    infraorbital nervewithin the orbit are

    the middle superior

    dental nerve and the

    anterior superiordental nerve, which

    contribute to the

    superior dental

    plexus.

    Modified from Grays Anatomy,

    Longmans, London, 35th Ed 1973

    p. 1005

    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

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    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

    As we haveseen, the nerve

    supply to the

    dental pulps of

    the upper teethand the nerve

    supply to the

    maxillary sinus

    are closelyrelated.

    http://www.septodont.ca/Septodont/english/other/cea_di01.html

    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

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    Uppe eet e e Supp yUppe eet e e Supp y

    The superior

    dental plexus isformed by

    twiglets from the

    posterior superior

    dental nerve, theanterior superior

    dental nerve, and

    the middle

    superior dentalnerve when it is

    present.

    http://www.septodont.ca/Septodont/english/other/cea_di01.html

    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

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    pp pp ypp pp y

    When the middle superior dental nerve is present, fibres fromthe posterior superior dental nerve supply the molar teeth and

    a twig to the second premolar.

    The middle superior dental nerve fibres supply themesiobuccal root of the upper first molar, the premolars, and

    may jointly supply the canine tooth.

    The anterior teeth as far back as the first premolar have

    twiglets from the anterior superior dental nerve.

    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

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    pp pp ypp pp y

    When the middle superior dental nerve is not present, then

    the upper posterior teeth as far back as the second premolarare supplied with twiglets by the posterior superior dental

    nerve, and anterior teeth as far back as the second premolar

    are supplied by the anterior superior dental nerve.

    Upper Teeth Nerve SupplyUpper Teeth Nerve Supply

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    There is no difference in the degree of sensitivity of the teeth

    regardless of the presence or absence of the middle superior

    dental nerve.

    The adjacent buccal gingivae are supplied by the same nerves

    that supply the dental pulps of the adjoining teeth.

    Upper Teeth AnaesthesiaUpper Teeth Anaesthesia

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    If pulpal anaesthesia is required, for example for a filling, then

    anaesthesia of these nerves is all that is required.

    If anaesthesia is required for extraction, however, then thenerve supply of the palatal tissues must also be

    anaesthetized, since these will be surgically detached during

    the procedure.

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    The End