Tree of Life: primary divisions
OEB 192 – 11.09.12
Tree of Life: three “domains”• Based on 16S rRNA (Woese, 1987):
Tree of Life: three “domains”• Based on 16S rRNA (Pace, 1997):
Bacteria & Archaeal: all genomes as of 12 Feb., 2010
(Lee, Robinson & Marx, in prep)
Microbial systematics
• Formerly Pseudomonas (partial list): Ralstonia, Burkholderia, Hydrogenophaga, Sphingomonas, Methylobacterium, Cellvibrio, Xanthomonas, Acidovorax, Hydrogenophillus, Brevundimonas, Pandoraea
multi-C C1(& all use methanol)
16S rRNA as phylogenetic marker• Why a good molecule?
70S 30S 50S
Tree basics: clades & character changes
Maximum Parsimony• Parsimony – shortest tree (fewest homoplasies)
Neutral theory• Developed by Motoo Kimura, 1968
Wednesday (9/14): Molecular evolution & phylogenetic inference:
case of HIV
& comment…