Towards an HIV Cure: Canadian <-> Global Stakeholder’s Engagement Workshop

21 July 2015, 18h30 – 20h30

The International AIDS Society (IAS) Towards an HIV Cure initiative, together with our Canadian partners CANFAR, CIHR, CanCURE and CATIE aim to encourage community contribution from

the diverse Canadian populations invested in HIV cure research. 

 In partnership with: Sponsored by:

Towards an HIV Cure: Canadian <-> Global Stakeholder’s Engagement WorkshopVancouver

Overview of the IAS Towards an HIV Cure Initiative: Community Efforts and Looking Towards 2016

Towards an HIV Cure: Mission

Facilitate scientific discussion, exchange and collaboration to promote and accelerate research towards a cure for HIV

Provide leadership in advocating for increased investment and resource optimization in HIV cure research

Provide clear and accurate information and disseminate knowledge to the broader community

Initiative Organisation

Adv

isor

y B

oardIndustry Collaboration Group

Cost-effectiveness Working Group

Psychosocial Studies Working Group

2014-2016 International Scientific Working Group

Ethics now integrated throughout the entire initiative

Advisory Board

Scientific Discussion, Exchange & Collaboration

Facilitate scientific discussion, exchange and

collaboration to promote and accelerate research towards

a cure for HIV

Global Scientific Strategy 2012

.

The International AIDS Society scientific working group on HIV Cure. Towards an HIV cure: a global scientific strategy. Nature Rev. Immunol. 18 Jul 2012 (doi: 10.1038/nri.3262)

Global Scientific Strategy 2016

Formation of International Scientific Working Group:

Steering Committee:

Jintanat Ananworanich, US Military HIV Research Program

Françoise Barré-Sinoussi, Institut Pasteur / Inserm

Monsef Benkirane, Institute of Human Genetics, CNRS

Steven Deeks, UCSF

Sharon Lewin, The Doherty Institute

Anna Laura Ross, ANRS / IAS

Joseph Tucker, UNC China Project

Global Scientific Strategy 2016

Identification of sub-groups

1. Molecular biology of HIV latency and shock strategies;Chairs: Monsef Benkirane & David Margolis

2. Viral reservoirs, immunology of HIV persistence and kill strategies;Chairs: Steven Deeks & Daniel Douek

3. Models for HIV cure or sustainable remission;Chairs: Jintanat Ananworanich & Jeffrey Lifson

4. Gene/cell therapy;Chairs: Paula Cannon & Daniel Kuritzkes

5. Novel biomarkers and technologies to analyse/quantify HIV reservoirs;

Chairs: Sharon Lewin & John Mellors

6. Social sciences and health system preparedness.Chairs: Joseph Tucker & Ying-Ru Lo

Global Scientific Strategy 2016

Timeline Action point

February – June 2015 Circulation of subgroup draft documents, coordinate development within sub-groups

22 June 2015 Submit developed text per sub-group to IAS

20 July 2015 2nd plenary meeting of ISWG

July – October 2015 First draft of the Global Scientific Strategy

November 2015 – January 2016

Peer review process of the Global Scientific Strategy

Q1, 2016 Pre-final version of Global Scientific Strategy

February 2016 3rd plenary meeting of ISWG

March/April 2016 Preparation of publication

July 2016 Aim to have article published and launch of the Global Scientific Strategy in Durban (full recommendations prepared and final)

Working Group activities

• Industry Collaboration Group

Enhance dialogue and interaction between public and private sectors

• Common MTA for the use of ARVs in pre-clinical studies

• Diagnostic companies;

• Therapeutic vaccination/immune modulation;

• Eradicare database.

• Cost-effectiveness and Public Health Working Group

• Opinion piece on the role of mathematical modeling and cost-effectiveness analysis in the HIV cure research agenda.

• Psychosocial Studies Group

• Joined forces with the Cost-Effectiveness and Public Health WG to write a multi-disciplinary scientific agenda for HIV cure research article.

Towards an HIV Cure Symposium

2010: HIV Reservoirs Workshop, Vienna2012: HIV Cure Symposium, Washington DC2013: HIV Cure Symposium, Kuala Lumpur2014: HIV Cure Symposium, Melbourne, Australia

2015: HIV Cure Symposium, 18th-19th July, Vancouver, Canada

Investment in HIV cure research

Provide leadership in advocating for increased investment and resource optimization in HIV cure

research

Evaluating and monitoring Investment

Resource TrackingSurvey of global investment in HIV cure research and development in 2012, 2013 and 2014

In collaboration with

Knowledge dissemination and information sharing

Provide clear and accurate information and disseminate

knowledge to the broader community

Knowledge dissemination and information sharing

www.towardsanhivcure.org

Community Engagement

Community Scholarships for the annual Towards an HIV Cure Symposium

Call for Nominations for Community Representatives to ensure fair representation in working groups and throughout the initiative

HIV cure fact-sheet developed in collaboration with community members

Community engagement and training workshops (Washington DC, Chennai, Melbourne, Vancouver…)

We want to hear your ideas and suggestions!

Acknowledgements

Sponsored by:

In Partnership with:

Acknowledgements

Towards an HIV Cure Initiative Sponsors:

www.towardsanhivcure.org