topical eye preparations 1. topical antibiotics. 2. analgesics. 3. decongestants and antihistamines....
TRANSCRIPT
Topical eye preparationsparapharmacuitics
Done by : Nadine AnabtawiSupervised by : Dr.Rana Abu Al-dahab
Topical eye preparations
1. Topical antibiotics.2. Analgesics.3. Decongestants and antihistamines.4. Irrigants.5. Artificial tears.6. Vitamin A products.
Topical antibiotics
1. Aminoglycosides.2. Fluroquinolones.3. Fucidic acid.4. Chloramphenicol.
1 .Aminoglycosides
• Gentamicin (Apigen®) and Topramicin (Tobrex® ointment , TopraDex® suspension) .
• Against gram positive and some gram negative bacteria .
• Used for bacterial infection in the cornea , eyelid and tear ducts.
• Side effects: burning and irritation.
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• Used for:1. Bacterial conjunctivitis . 2. Blephritis .3. After removal of foreign bodies or
abrasions.4. After chemical or physical agent
damage.5. Before and after eye surgery.
Fluoroquinolones
• Ofloxacin (Oflox® ).Ciprofloxacin (API-Ciprocin ®)
• Bactericidal .• Used for bacterial conjunctivitis and otitis
media.
Fucidic acid
• Optifucin ®• Used against Staph. and Strep.
Infections.• Uses : 1. Bacterial conjunctivitis.2. External hordeolum .
Chloramphenicol
• Phenicol ®• Bactericidal.• Mainly against gram negative as
hemophillus influenzea Bacterial conjunctivitis .
• Store between 2-8°C refrigerated .
2 .Analgesics
• Diclofenac 0.1% ( voltaren ®).• Welder’s arc .• Blunt truma need oral or topical
analgesic.
3 .Decongestants and antihistamines• For allergic and viral conjunctivitis.• Naphazoline hydrochlroride +
Pheniramine maleate (Naphcon A ®)• Apillerg ® /Spersallerg ®
• Decongestant alone Tetryzoline ( Efemoline ®)
• Antihistamine alone Ketotifen (Zaditen ®)
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4 .Irrigants
• Sodium chloride 0.9 % ( Apisal ® )• Used for eye washing.• Not used if contact lens is in place.
5 .Artificial tears
• Used for dry eye and minor thermal damage.
• Carboxymethyl cellulose CMC Refresh tears ® , Refresh Plus ®, Celluvisc ®
• Hydroxypropyl methyl cellulose HPMC Genteal ® , Genteal Gel ®
• Carbomer Liposic ®
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6 .Vitamin A products
• Very important for vision accuracy .• Deficiency will lead to degenerative
opthalmic conditions.• Oral preparations.