tobacco additives: the increased health · pdf file(guar gum: combustion ... excerpts from us...

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Dr. Martina Pötschke-Langer Unit Cancer Prevention and WHO Collaborating Centre for Tobacco Control, German Cancer Research Center (DKFZ) Heidelberg,Germany email: [email protected] Tobacco additives: The increased health risk

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Page 1: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Dr. Martina Pötschke-Langer

Unit Cancer Prevention and WHO Collaborating Centre for Tobacco Control,

German Cancer Research Center (DKFZ) Heidelberg,Germanyemail: [email protected]

Tobacco additives:The increased health risk

Page 2: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

International consensus:Ban on or regulation of all tobacco additives

Tobacco additives:The increased health risk

Partial guidelines for implementation of Articles 9 and 10 of the WHO FCTC

WHO Framework Convention on Tobacco Control (FCTC)Articles 9 and 10

Page 3: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

More than 600 additivesare used in cigarette production

German Cancer Research Center 2013

Tobacco additives:The increased health risk

„Ingredients are indeed used to make cigarettesmore palatable, and to reduce harshness and irritation.“

(House of Commons Health Committee, Memorandum by BAT

“The Tobacco Industry and the Health Risks of Smoking“, 1999)

Page 4: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Examples of tobacco additives

Sugars

German Cancer Research Center, 2013

Page 5: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Menthol

Examples of tobacco additives

German Cancer Research Center, 2012

Page 6: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Liquorice

Examples of tobacco additives

PITOC 2012, German Cancer Research Center 2013

Page 7: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Additives without flavour• binders

(guar gum: combustion carcinogenic substances)

• humectants (moisturing agents) (glycerol, sugar: combustion carcinogenic substances)

• colouring agents (azo dyes: tartrazine (yellow): carcinogenic)

PITOC, http://www.dkfz.de/de/tabakkontrolle/PITOC_Additives_in_Tobacco_Products.html;Deutsches Krebsforschungszentrum (Ed.): Increased Health Hazards due to Additives of Tobacco Products – Consequences for Product Regulation. Heidelberg 2005

Examples of tobacco additives

Page 8: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Tobacco products with characterising flavours

Only a small market!

Tobacco additives:The increased health risk

Page 9: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Big market: Mix of many additives

• flavours in very low amounts „Ingredients are indeed used to make cigarettes more palatable, and to reduce harshness and irritation.“ (BAT,1999) facilitation of initiation and maintenance of smoking

• interaction and synergistic effects of additivesmixture of small amounts of several additives can havesimilar effects as bigger amounts of single additives

• many additives produce carcinogenic substances on pyrolysis:

no harmless threshold levels for additives

Tobacco additives:The increased health risk

Page 10: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Tobacco additives:The increased health risk

New technologies

• enhance attractiveness

• capsule can be filled with any additive

Excerpts from US patent No. 7878962 (Karles et al., Philip Morris)

Page 11: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

What should be done?

Revision of the EU Directive 2001/37/EC

• to protect youth from initiation

• to support smokers to quit smoking

Ban of all additives that may enhance the palatability,

smoothness and attractiveness of tobacco products

Why?

Page 12: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

What should be done?

Revision of the EU Directive 2001/37/EC

Ban of all additives that are carcinogenicin unburnt or burnt form

• to protect consumers

• to reduce morbidity and mortality

Why?

Page 13: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

What should NOT be done?

Revision of the EU Directive 2001/37/EC

Set maximum levels for any additives

• no reliable methods to define a threshold level for distinctive taste

• many interactions between additives with synergistic effects on palatability, smoothness and inhalation

Why?

Page 14: Tobacco additives: The increased health · PDF file(guar gum: combustion ... Excerpts from US patent No. 7878962 (Karles et al., Philip Morris) ... • manufacturers and importers

Summary

Revision of the EU Directive 2001/37/EC

• ban is needed on additives that enhance palatability, smoothness and attractiveness of tobacco products

• ban is needed on additives that are carcinogenic in unburnt or burnt form

• manufacturers and importers must prove that any additive they want to use is harmless