thought induced gene expression
TRANSCRIPT
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Thought Induced Gene
Expression
Brishav RajbahakAbhishesh Bajracharya
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Contents
IntroductionProcess
Scope
ResutsRe!erences
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Introduction
Gene reguation "ethod that enabesthought-specifc brainwaves tocontro the conversion o! genes intoproteins
Tap into hu"an brain#aves$ trans!erthe" #ireessy to a gene net#ork andreguate the expression
o! a genedependingon the type o!thought
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%u"an thoughts can be used to turn on
genes in "ice via genetically modifedcells (implants)
A tiny$ ight&based "achine uses peope'sbrain #aves to generate a (icker o! ight$
#hich then turns on genes in the brains o!"ice
Martin Fussenegger$ a pro!essor o!biotechnoogy and bioengineering$ and his
tea" at the Department o Biosystems(B-BSS)! "# $urich in S#it)eranddeveoped this gene reguation techni*ue
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+E, ight$ to be i"panted in "ice- Expresses gene in"odi.ed ces #hen s#itched on-
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Process
In their study$ /ussenegger and hiscoeagues asked severa vounteers tomeditate or concentrate 0by paying aga"e o! 12inecra!t34 or contro their brain
activity #ith bioeedbac% $ 0a techni*ue#here peope sync their brain #aves usinga guided dispay4
The brain#aves thus produced #ere
recorded and anay)ed by an & headsetand !ed #ireessy via buetooth to acontroer that "anages a feld generator
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This .ed generator created an
electromagnetic feld #hich gave thei"pant an induction current
The induction current turns on an 'D
lamp in the i"pant #hich e"its near-inrared light
A ight&sensitive "odue reacts to near&in!rared ight #hich shines on a modifed
light-sensitive bacterial protein #ithin the i"pants
This turns on a tailor-made gene snippet that encodes a speci.c hu"anprotein5 S 0Secreted Akaine
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Resuts
Test subjects #ho payed 2inecra!t on theco"puter$ i-e- #ho #ere concentrating$induced average S values in theboodstrea" o! the "ice
Subjects #ho #ere co"petey reaxed0"editation4 recorded very high Svalues in the boodstrea" o! "ice
/or bio&!eedback$ the test subjects #ere
abe to consciousy s#itch the +E, ight onor o6 via the visua !eedback- This in turn#as re(ected by the varying amounts oS in the boodstrea" o! the "ice-
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The optogenetic i"pant$ seen through the skin o! "ice-
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Scopes
Coud be used by peope #ho su6er!ro" chronic headaches or epilepsy to instanty deiver drugs !ro" a braini"pant #hen they experiencecharacteristic brain #aves at the onseto! pain or a sei)ure-
Coud eventuay be used in the hu"an
brain to deliver precise *uantitieso drugs as needed- Eg- Pain"anage"ent 7 reease o! endorphins
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,ra#backs
.nding reiabe signas o! inessin a !u))y "ass o! brain#aves
i"pants get covered #ith .brotic
scar tissue ha"pering the reeaseo! any proteins !ro" the i"pant
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Re!erence
http588###-sciencedaiy-co"8reeases89:;
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Thank @ou