thm61144 guided surgery en 002 ab · 910 11 12 rc lc mc mono insertion tools screwdrivers...
TRANSCRIPT
GUIDED SURGERY.PF 3.5–PF 4.5 / L 6.5–L 12.5
Contents
2 © Thommen Medical
1. At a glance
3 Intended use
3 Restrictions for use
3 Processing
3 Storage
2. Cassette and instruments for guided surgery
4 ELEMENT & CONTACT PF 3.5–PF 4.5 /
L 6.5–L 12.5, all collars
3. Planning and preparation
6 Drill template preparation
6 Drilling
6 Anatomical structures
4. Basic preparation (VECTOdrillTM)
7 Double guidance principle
7 Drilling
7 Guide sleeve
5. Fine preparation (profile drills)
8 Select profile drill
6. Implantat insertion
9 Implant pick up and click into place for
implant insertion
9 Implant insertion: Visual Depth Control
9 Rotational index: Implant alignement
7. Drilling sequence
10 General
10 Sample 1, ELEMENT RC, PF 3.5 / L 11.0
10 Sample 2, CONTACT RC, PF 4.0 / L 9.5
8. Guide sleeve mounting
11 Processing
11 Drill templates
11 Functional check
9. Important
12 Precautions
10. Torque values
13 Torque values
11. General notes
14 General notes
1. At a glance
© Thommen Medical 3
These instructions apply to all instruments specific for guided
surgery PF 3.5–PF 4.5 / L 6.5–L 12.5, as shown on page 4/5 in
this document.
ONLY use original Thommen Medical drills with a gui-
ding cylinder � 4.8 mm in combination with original
guide sleeves � 4.8 mm
For guided surgery of other platforms and lengths, refer to the
VECTOdrill™ pilot drill solution www.ifu-tm.com/THM61141.
For more information regarding the standard surgical proce-
dure including the use of standard instruments, refer to www.
ifu-tm.com/THM61141. For more information regarding the
Thommen 3.0 implant system, refer to www.ifu-tm.com/
THM61146.
Intended use
Thommen Medical instruments are to be used in conjunction
with the Thommen Medical dental implant system in the max-
illary and/or mandibular arch.
Restrictions for use
See general restrictions of use (see p. 14).
Processing
Process cassette and instruments before first-time use.
For processing instructions, refer to www.ifu-tm.com/
THM61131.
Storage
Cassette for guided surgery (art. No. 1.04.020) must be pro-
tected from exposure to strong light and heat sources and
stored at room temperature.
4 © Thommen Medical
MCMC RC
PF
3.5
PF
4.0
PF
4.5
PF
3.5
PF
4.0
PF
4.5
PF
3.5
PF
4.0
PF
4.5
–
–
CONTACT ELEMENT
Guided Surgery
L 11.0L 8.0
L 12.5L 9.5L 6.5
6.5
8 11
12.59.5
ELEM
ENT
CON
TACT
1 2 3 4 5 6 7 8
MC
RC
Fine Preparation Basic Preparation
PF 3.5–PF 4.5 / L 6.5–L 12.5
START � 2.0/L 4.0
L 6.5 L 8.0L 9.5
� 2.0
� 2.8
� 3.5
L 11.0L 12.5R
emov
e in
sert
for
clea
ning
Basic preparation
VECTOdrill™ pilot drill and twist drills, guided
Stainless steel
L 6.5 L 9.5 L 12.5 L 8.0 L 11.0
Lenght mm 31.5 34.5 37.5 33.0 36.0
� 2.0 3.04.111 3.04.113 3.04.115 3.04.112 3.04.114
� 2.8 3.04.121 3.04.123 3.04.125 3.04.122 3.04.124
� 3.5 3.04.131 3.04.133 3.04.135 3.04.132 3.04.134
Cassette for guided surgery 1.04.020
Specific slots are provided for loading of the instru-
ments. Refer to dental shaft and graphic insert.
Example:
Basic preparation
initial drill, guided
Stainless steel
L 4.0
Lenght mm 28.5
� 2.0 3.04.110
Fine preparation
profile drills, guided
Stainless steel
CONTACT MC CONTACT RC ELEMENT MC
Lenght mm 34.0 32.5 30.5
� 3.5 3.04.171 3.04.161 3.04.151
� 4.0 3.04.172 3.04.162 3.04.152
� 4.5 3.04.173 3.04.163 3.04.153
2. Cassette and instruments for guided surgery
20maxLOT
5°C/41°F
5°C/41°F
20maxLOT
800 rpm 600 rpm800 rpm 500 rpm
� 2.8� 2.0 � 3.5� 2.0/L4.0
250 rpm
L 6.5
� 2.8 � 2
.8 /
L6.
5
5°C/41°F
ELEMENT & CONTACT PF 3.5–PF 4.5 / L 6.5–L 12.5, ALL COLLARS
20maxLOT
© Thommen Medical 5
B
C
D
E
Optional Instruments
Implant Insertion
9 10 11 12
RC
MCLC
MONO
Insertion tools Screwdrivers
Screwdrivers
Implant Insertion
adapter, guided
Stainless steel
Adapter, guided Screwdriver, short Screwdriver, extra short
Lenght mm 25.5 22.0 17.0
3.04.090 3.03.501 3.03.500
Optional Instruments*
Along with the clearly designated slots, additional slots are provided
that can be loaded as required.
* Standard instruments (refer to www.ifu-tm.com/THM61141)
Max. 20 application cycles (surgery, cleaning, sterilization) for cutting instruments.
Futher application cycles do not guarantee the function of the product anymore.
Cooling during irrigation, approx 5° C/ 41 °F.
MONO
insertion device*
Stainless steel/PEEK
3.03.162 3.03.163
MONO
screwdriver*
Stainless steel/PEEK
3.03.165 3.03.166 3.03.167
MONO guide key*
Stainless steel
3.03.203
MONO torque ratchet*
Titanium alloy
3.03.160
Guide sleeve
Stainless steel
Lenght mm 5.0
� 4.8 3.04.080 Q4
15 rpm
20maxLOT
5°C/41°F
Seating instrument
for guide sleeves
Stainless steel
� 4.8 3.04.100
6 © Thommen Medical
Drilling
All VECTOdrill™ drills are 0.5 mm longer apically than
the specified length of the respective Thommen implants.
In order to avoid complications, this must be taken into
account when choosing the dimensions and the position-
ing of the implant, particularly in proximity to anatomical
structures.
Note: In case guided surgery cannot be performed as planned,
guided instruments are suitable for unguided procedure:
· For depth control, use depth markings as indicated on
graphic insert
· Start with VECTOdrill™ pilot drill, guided, do not use initial
drill, guided
· Sequential preparation with VECTOdrill™ twist drills,
guided, and profile drills, guided, if required
· For implant insertion, use adapter, guided
Check the drilling depth of the im plant bed after the
first pilot drill step with the respective laser marks on
the drill or with the depth gauge.
Anatomical structures
The mesiodistal position of implants can be estimated by using
a periodontal probe placed vestibularly or determined with a
gauge. The required minimal gap width for the sleeve and min-
imal hight for the instruments have to be taken into consider-
ation.
In case of narrow situations or guided pilot drilling only, use guide
sleeve for VECTOdrill™ pilot drill � 2.0 mm (art. no. 3.03.141).
Planning software: Please refer to www.thommenmedical.com
for information about compatible planning software solutions.
Drill template preparation
Before surgery, the drill template must be tested for correct
function (correct fit, stability, size limitations) in the patient’s
mouth. The orientation of the guide sleeves must agree with
preoperative planning. The respective manufacturer of the drill
template ensures the compatibility of the Thommen Medical
guide sleeves with the drill template. For sleeve mounting see
p. 11.
0.5
E
PF
L 11.0
ThommenImplant System
≥ 1.5 mm ≥ 1.5 mm≥ 3.0 mm
Bone level
3. Planning and preparation
© Thommen Medical 7
4. Basic preparation (VECTOdrill™)
Double guidance principle
All VECTOdrill™ twist drills feature a tapered tip which has the
same diameter as the shaft of the preceding drill. The axis
guidance thus prevents slippage of the drill and ensures a pre-
cisely shaped implant bed.
You must not skip short drills to ensure double guidance.
Drilling
All holes must be drilled by constantly cooling the exte-
rior with physiological, sterile, cooled saline solution
(approx. 5°C/41°F). Recommended rotation speeds
(page 4) must be adhered to in order to avoid overheat-
ing the bone tissue and possible instrument fractures.
Lateral loads must be avoided to ensure retention of the
guide sleeves in the drill template. Drilling must only
start as the drill is positioned on the bone. Ensure con-
tinuous rotation of the drill during removal from the
bone.
Guide sleeve
The guide sleeves are for single use only. Multiple use
does not guarantee correct function of the sleeve any-
more.
Physical depth control
Laser marks for depth control
One sleeve offset (5.0 mm)
VECTOdrill™ geometry
and guidance
� 2.8/L 11.0 � 3.5/L 11.0 � 3.5/L 8.0
10.0 mm
� 4.8 mm
� 5.3 mm
5.0 mm
8 © Thommen Medical
Select profile drill
according to implant type and platform as indicated on graphic insert.
5. Fine preparation (profile drills)
ELEMENT MC ELEMENT RCCONTACT MC
Bone level
No profile
drill needed
CONTACT RC ELEMENT LC
© Thommen Medical 9
6. Implant insertion
Implant pick up and click into place for implant insertion
You must CLICK! to ensure correct depth control during implant insertion. Check also visually.
1
LC RC MC
2 3 4
Follow same procedure for standard implant packaging.
CLICK! CLICK!
Rotional index: Implant alignement
Bone level
Implant insertion: Visual Depth Control
10 © Thommen Medical
7. Drilling sequence
General
IV
III V
VI
III
I Start with initial drill always
II Choose length
III Choose implant type and PF
IV Identify last VECTOdrill™ and follow
the lines on the graphic insert
V Use profile drill if needed
VI Use adapter for implant insertion
ELEMENT RC: No profile drill needed
(see p. 8).
1
2
4
3
5
6
Sample 1, ELEMENT RC, PF 3.5 / L 11.0
1
2 3
4 5 6
7
Sample 2, CONTACT RC, PF 4.0 / L 9.5
© Thommen Medical 11
Drill templates The diameter of the printed sleeve cavities may vary depending on
the 3D printing system that is utilized. In case diameter corrections
are needed, refer to the design settings if existing. Please check
www.thommenmedical.com for recommended printing systems.
Functional check
· Sleeve must sit tight
· Seating instrument must fit and slide
· Sleeve edge must be placed vertically correct
8. Guide sleeve mounting
Guide
sleeve � 4.8 mm/L 5.0 mm 3.04.080 Q4
2 31
Handle for dental
laboratory 3.03.250
Seating instrument MUST be used for sleeve mounting and functional check.
Seating instrument for
guide sleeves � 4.8 mm 3.04.100
Processing
Guide sleeve is suitable for the sterilization method as de-
scribed in www.ifu-tm.com/THM61131.
Process drill template before use according to manu-
facturer’s instructions. It must be ensured that the
guide sleeves are firmly and correctly fixed in the drill
template before use.
12 © Thommen Medical
Precautions · Process cassette and instruments before first-time use
· For processing instructions refer to: www.ifu-tm.com/THM61131
· Max. 20 application cycles (surgery, cleaning, sterilization) for cutting instruments. Further sterilization cycles do
not guarantee the function of the product anymore
· Specific slots are provided for loading of the instruments: refer to dental shaft and graphic insert
· Process drill template for use according to manufacturer’s instructions
· It must be ensured that the guide sleeves are firmly and correctly fixed in the drill template before use
· Replace broken or dull instruments before surgery
· All VECTOdrill™ drills are 0.5 mm longer apically than the specified length of the respective Thommen implants. In order
to avoid complications, this must be taken into account when choosing the dimensions and the positioning of the implant,
particularly in proximity to anatomical structures
· ONLY use original Thommen Medical drills with a guiding cylinder � 4.8 mm in combination with original guide sleeves
� 4.8 mm
· Drilling must only start as the drill is positioned on the bone. Ensure continuous rotation of the drill during removal
· Recommended rotation speeds must be adhered to in order to avoid overheating the bone tissue and possible instru-
ment fractures
· All holes must be drilled by exerting slight pressure intermittently while constantly cooling the exterior with physio-
logical, sterile, cooled saline solution (approx. 5°C/41°F)
· Regularly remove the bone chips to ensure ideal drilling performance
· Check the drilling depth of the implant bed after the first pilot drill step with the respective laser marks on the drill
or with the depth gauge
· You must CLICK! to ensure correct depth control during implant insertion. Check also visually
· The guide sleeves are for single use only. Multiple use does not guarantee correct function of the sleeve of the pro-
duct anymore
· Seating instrument MUST be used for sleeve mounting and functional check
· Guide sleeve mounting: Sleeve must sit tight, seating instrument must fit and slide, sleeve edge must be placed ver-
tically correct
9. Important
© Thommen Medical 13
10. Torque values
ABUTMENT/SCREW TORQUE VALUES IN Ncm
10 15 20 25 30
Healing cap
Gingiva former
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
Abutment screw
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
Abutment screw in combi-
nation with ART Abutment
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
VARIOmulti abutment
Novaloc® abutment
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
VARIOmulti protective cap
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
Occlusal screw
(VARIOmulti, VARIO 17º, bar)
Occlusal closure screw,
for CAD/CAM bar
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
Retentive anchorPF � 4.0
PF � 4.5
PF � 5.0
ZEST® LOCATOR® abutment
PF � 3.5
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
ZEST® LOCATOR® abutment
and collar for VARIOmulti
PF � 4.0
PF � 4.5
PF � 5.0
PF � 6.0
New abutment screws must be used for permanent insertion of the restoration in the mouth.
�
�
11. General notes
THOMMEN IMPLANT SYSTEM
Manufacturer: Thommen Medical AG
Neckarsulmstrasse 28
2540 Grenchen, Switzerland
www.thommenmedical.com
Batch code
Use by date
Date of manufacture
Sterilized using irradiation
Sterilized using steam or dry heat
Temperature limitation
Do not re-use
Non-sterile
Caution
Article number
Conformity symbol as specified
by EU Directive MDD 93/42/EEC
Consult instructions for use
Do not resterilize
Do not use if package is damaged
Atmospheric pressure limitation
Manufacturer
Keep away from sunlight
May only be sold to and prescribed by
physicians (USA)
COLOURED WARNING STICKER
Application has changed - follow the corresponding instruc-
tions for use.
New design – the application has not been changed.
PRODUCT INFORMATION The information in this document
describes the application of the Thommen Medical implant
system. This information is available in electronic form online
at: www.ifu-tm.com. For technical advice, please refer any
questions to your country's representative or distributor of
Thommen Medical products.
COLOR CODE Each implant platform diameter has a color
code, which can be found on all implant and abutment
packagings, on the impression items and on most diameter-
specific instruments.
Brown = PF 3.0
Yellow = PF � 3.5 mm
Green = PF � 4.0 mm
Blue = PF � 4.5 mm
Grey = PF � 5.0 mm
Purple = PF � 6.0 mm
AVAILABILITY Not all of the Thommen Medical products
mentioned in these instructions for use are available in all
countries. Refer to the representative or distributor of
Thommen Medical products in your country regarding avai-
lability.
GENERAL RESTRICTIONS OF USE Restorations with can-
tilevers to individual implants are not recommended. Indivi-
dual restorations with angled abutments should not be used
in regions with high mechanical stress. For implants with a
small diameter (PF 3.0 and 3.5), the prosthetic restoration
should be constructed in such a way that a large bending
moment does not occur. The Thommen Medical products
may not be used on patients who are known to have allergies
to the corresponding materials.
POSSIBLE COMPLICATIONS A stressed loading of the implant
or abutment over and above its functional capacity can lead
to excessive bone loss or fracture of the implant or restoration.
The clinician must supervise the occlusion and functional
loading of the prosthetic supraconstruction very carefully.
WARNINGS/PRECAUTIONS All Thommen Medical products
that are used or placed in the oral cavity must be protected
from aspiration. Thommen Medical products have not been
evaluated for safety and compatibility in the MR environ-
ment. Thommen Medical products have not been tested for
heating, migration, or image artifact in the MR environment.
The safety of Thommen Medical products in the MR environ-
ment is unknown. Scanning a patient who has this product
may result in patient injury.
RESPONSIBILITY/LIABILITY As a part of an overall scheme,
Thommen Medical products may be used only with the ori-
ginal components and instruments in accordance with the
instructions for use provided by Thommen Medical. The use
of non-system parts may compromise the performance of
Thommen Medical products and lead to failures. Users must
have appropriate knowledge and information about the
handling of Thommen Medical products in order to use the
products safely and professionally in accordance with the in-
structions for use. Thommen Medical products should only
be used in accordance with the instructions for use provided
by Thommen Medical. The user is obliged to use the Thommen
Medical products according to the instructions for use and
to check whether the product is suitable for the individual
patient situation. The use of Thommen Medical products is
the responsibility of the user, as such, is beyond the control
of Thommen Medical AG. We refuse to accept any responsi-
bility or liability for any damage due to incorrect utilization
of the product. Products labeled “Do not re-use” may not be
refurbished and/or reused. The refurbishment and/or reuse
of these products can affect their function (e.g. fitting and/
or cutting properties) as well as their safe use (e.g. risk of
infection, disease transmission, fading of the laser or color
marks, corrosion). Detailed information about the possible
consequences, which may result from negligence to follow
this information, can be obtained from your country's repre-
sentative or distributor of Thommen Medical products.
CAUTION Federal law (USA) restricts this device to sale to
by or on the order of a dentist or physician.
GUARANTEE The comprehensive guarantees can be found
in the country-specific guarantee leaflets.
TRANSPORT AND STORAGE Please note the specifications
on all labels and package leaflets regarding transportation,
storage and instructions for use. Products whose packaging
is damaged must not be used. Under no circumstances may
Thommen Medical products be used beyond the expiration
date, as proper functioning or sterility of sterile packaged
products cannot be guaranteed by the manufacturer
anymore.
INSTRUCTIONS FOR USE The following information is not
intended as comprehensive for the Thommen Implant Sys-
tem. New customers are advised to undergo training by a
specialist experienced in the use of this system.
GUARANTEE OF STERILITY Products of the Thommen Implant
System supplied in sterile packaging must not be re-steri-
lized. If the sterile packaging is damaged during transport
or storage, the product may under no circumstances be
used. Products that have been opened and have not been
immediately used for the intended operation must not be
used thereafter. After resterilization, the safety, function
and efficacy of the product cannot be guaranteed by the
manufacturer. The products intended for single use must
never be reprocessed, sterilized or reused and must be dis-
posed of safely and properly after use in compliance with all
applicable legal and regulatory requirements. Reusable
products must be reprocessed according to the instructions
for use and, if used on patients, sterilized. They must be
checked for their integrity before each use. Any damage
(such as scratches, cracks, nicks, notches), as well as bent
parts mean that they must not be used any more. The
number of reprocessing cycles is limited and must be moni-
tored. If the number of cycles is exceeded, proper function
and sterility of the product are not guaranteed by the manu-
facturer anymore.
DISPOSAL Products that have been used on a patient are
considered infectious. In the case of cutting products, there
is always a risk of injury. Therefore, the products must be
disposed of safely and properly after use, observing all
applicable legal and regulatory requirements. After applica-
tion, they must be disposed of safely and properly in compli-
ance with all applicable legal and regulatory requirements.
COPYRIGHT©/REGISTERED® SPI®, INICELL® and APLIQUIQ®
are registered trademarks of Thommen Medical AG. Publi-
cation or reproduction is permitted only with the written
consent of Thommen Medical AG. LOCATOR® is a registered
trademark of Zest Anchors Inc., CA, USA. Novaloc® is a re-
gistered trademark of Valoc AG, Möhlin, CH.
VALIDITY © Thommen Medical AG. All rights reserved. This
instruction for use replaces all previous editions.
© Thommen Medical 15
HEADQUARTERS
Thommen Medical AG
Neckarsulmstrasse 28
2540 Grenchen | Switzerland
Tel. +41 61 965 90 20
Fax +41 61 965 90 21
SUBSIDIARIES/NATIONAL DISTRIBUTORS
AUSTRALIA/NEW ZEALAND
Osteon Medical
23/1866 Princess Highway
Clayton Victoria 3168 | Australia
Tel. (inside Australia): 1300 411 473
Tel. (outside Australia): +61 3 9264 0111
www.osteonmedical.com
AUSTRIA
Thommen Medical Austria GmbH
Simmeringer Hauptstrasse 24
1110 Wien | Austria
Tel. +43 660 2011953
BENELUX
Thommen Medical Benelux B.V.
Dierenriem 1
3738 TP Maartensdijk | Netherlands
Tel. +31 30 68 68 468
CHINA
Shanghai Yujing Trading Co., Ltd.
Room G | Floor 15th | Plaza JiaFa | No.1
Lane 129 | DaTian Road | JingAn District
Shanghai | China
Tel. +86 21 62723077
Fax +86 21 62175264
FINLAND
Vector Laboratories Oy
Engelinaukio 8 B
00150 Helsinki | Finland
Tel. +358 400 940 700
FRANCE
Thommen Medical France
10 avenue Gabriel Pierné
77680 Roissy-en-Brie | France
Tel. +33 1 83 64 06 35
Fax +33 3 89 33 52 53
GERMANY
Thommen Medical Deutschland GmbH
Am Rathaus 2
79576 Weil am Rhein | Germany
Tel. +49 7621 422 58 30
Fax +49 7621 422 58 41
HONG KONG
Shengyuan (Hong Kong) Int. Trade Co. Ltd.
Level 13, 68 Yee Wo Street
Causeway Bay | Hong Kong
Tel. +852 530 876 41
ITALY
Dental Trey S.r.l.
Via Partisani, 3
47016 Fiumana | Predappio (FC) | Italy
Tel. +39 0543 929111
Fax +39 0543 940659
www.dentaltrey.it
JAPAN
J. Morita Corporation
3-33-18, Tarumi-cho
Suita | Osaka 564-8650 | Japan
Tel. +81 6 6384 6921
Fax +81 6 6384 6746
www.morita.com
LITHUANIA/LATVIA
CERNIKIS MEDICAL PROJECTS, UAB
Siaures prospektas 5B, Kaunas
Lithuania LT-49191
Tel. +370 37 201072
Mobile +370 65 771550
www.cmp.lt
MIDDLE EAST
Star Science International GmbH
Jupiterstrasse 57
3015 Bern | Switzerland
Tel. +41 31 941 07 31
Fax +41 31 941 07 33
NORWAY
Novus Dental AS
Johannes Bruns gate 5
0452 Oslo | Norway
Tel. +47 951 07 007
www.novusdental.no
POLAND
C.WITT DENTAL Sp. z o. o.Ul. Granitowa 1087-100 Toruń | NIP 951-15-08-371 | PolandTel. +48 56 623 61 [email protected]
REPUBLIC OF CROATIA
Futura Dental d.o.o.
Kralja Zvonimira 108
10 000 Zagreb | Republic of Croatia
Tel. +385 91 6814 860
www.futura-dental.hr
RUSSIAN FEDERATION
CIS – JSC Geosoft
Build. 14, Ap. 16, 3-ya Mytishchinskaya ul.
Moscow, 129626 | Russian Federation
Tel. +7 495 663 22 11
SINGAPORE
FONDACO Pte Ltd
7 Kaki Bukit Road 1, #03-06
Eunos Techno Link
Singapore 415937 | Singapore
Tel. +65 6392 2806
Fax +65 6392 1296
SOUTH KOREA
APS Advanced Prosthetic Solution
201, Kolon Aston
505-14 Gasan-dong Geumchoen-gu
Seoul | South Korea
Tel. +82 2 3141 2875
Fax +82 2 3141 2877
www.apsdd.com
SPAIN/PORTUGAL
ISP Implante Suizo de Precisión
C/Los quintos n 1
03350 Cox (Alicante) | Spain
Tel. +34 96 536 1020
Fax +34 96 536 1188
SWITZERLAND
Thommen Medical AG
Neckarsulmstrasse 28
2540 Grenchen | Switzerland
Tel. +41 32 644 30 20
Fax +41 32 644 30 25
TAIWAN
En-Jye International Co., Ltd.
No. 18 | Lane 177 | Sec 3 | Chengde Rd.
Taipei, 103 Taiwan
Tel. +886 2 2585 1669
Fax +886 2 2585 0892
TURKEY
Bioport Biyolojik Maddeler A.S.
Büyükdere cd. Subay evleri 9. Blok D1 Esentepe
Sisli 34394 Istanbul | Turkey
Tel. +90 212 2727577
Fax +90 212 2727628
www.bioport.com.tr
USA/CANADA
Thommen Medical USA L.L.C.
1375 Euclid Avenue | Suite 450
Cleveland OH 44115 | USA
Tel. +1 866 319 9800 (toll free)
Fax +1 216 583 9801
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