mrI+

Update: Thermal Workshop on RF Hotspots

IT’IS Foundation Zurich, SwitzerlandMarch 21 – 22, 2011www.itis.ethz.ch

Objectives

MRI+ is a research consortium (www.mriplus.org) initiated under the funding umbrella EUREKA of the European Union to develop a new basis for assessing the RF safety of MR scanners. As the importance of the research initiative drew broader interest, the project was extended with the par-ticipation of new partners from the USA. Given the growing development and introduction of new and evolving MR modalities, the consortium concluded that future safety guidelines should be based on local temperature hotspots rather than SAR limits. The consortium has invited a panel of world experts to present the latest research findings and to discuss the concept of setting safety limits for local hotspots as developed by Prof. Dr. Gerard van Rhoon.

Late Registration (4 seats still available)

Full registration: EUR 300.00Student registration: FreeDeadline for registrations: March 18, 2011 Registration email: irissz@itis.ethz.ch, phone: +41 44 245 9696

Venue

IT’IS Foundation LabsZeughausstrasse 438004 Zurich, Switzerland+41 44 245 9686

Map of location of IT’IS Labs in downtown Zurich:

MONDAY, MARCH 21, 2011 TUESDAY, MARCH 22, 2011

SESSION 1 Scope of the Workshop Thermoregulation and Mechanisms of Hazard by Small Local Heating

SESSION 4

CHAIR Manuel Murbach Wolfgang Kainz CHAIR

SCHEDULE 09:30 Coffee

10:00 Niels Kuster IT’IS Foundation, Zurich, Switzerland

Welcome and goals of the workshop

10:15 Johan van der Brink�Philips, Eindhoven, NetherlandsMR thermal safety: Practical considerations

10:45 Wolfgang KainzFDA, Silver Spring, MD, USARF Hotspots in multi-channel transmit MR coils

11:15 Marvin Zisk�inTemple University, PA, USAThe standard perspective

11:45 Business Lunch

08:00 Coffee

08:30 Jacek� NadobnyCharité, Berlin, GermanyStatus quo of the evaluation of in vivo experiments in swine respective the consequences of high load RF exposures

09:15 Michael R. HorsmanAarhus University, Aarhus, Denmark� Local thermoregulation; vascular effects at low temperature increases

10:00 Elisabeth Repask�yRoswell Park� Cancer Institute, Buffalo, NY, USAMechanisms underlying thermal modulation of cellular immune responses

10:45 Coffee

11:00 Berina Eppink� ERASMUS, Rotterdam, NetherlandsDNA repair as a function of temperature

SCHEDULE

SESSION 2 SAR and Temperature Modeling

CHAIR Matthias Gebhardt

SCHEDULE 12:30 Manuel Murbach IT’IS Foundation, Zurich, Switzerland

MRI exposuresLocal SAR vs. whole-body averaged SAR;in vivo validation

13:00 Esra Neufeld IT’IS Foundation, Zurich, Switzerland Thermal simulation models; material parameters; body core heating

13:30 Theodoros SamarasRCL, Thessalonik�i, Greece The correlation between RF power deposition peaks and thermal hotspots

14:00 Coffee

Discussion and Closing SESSION 5

Gerard van Rhoon CHAIR

11:45 All General discussion and conclusions for MRI exposureModerator: Gerard van Rhoon

12:00 Closing of the work�shop

SCHEDULE

SESSION 3 Tissue Damage Models and RF HazardsThresholds & Uncertainties

Research at IT’ISIncl. Small Lunch

AFTER SESSION

CHAIR Heinrich Walt Myles Capstick� CHAIR

SHEDULE 14:30 Gerard van Rhoon ERASMUS, Rotterdam, Netherlands

Time-temperature relationship; CEM43 ap-proach and projection to small temperature increases; a safe time–temperature relation

15:30 Raphael Lee University of Chicago, Chicago, IL, USA

Consequences of electrothermal heating

16:15 Joe Roti Roti Washington University, St. Louis, MO, USA

Heat shock proteins (by webex)

17:00 Marvin Zisk�inTemple University, PA, USAShortcomings and uncertainties of the CEM43 models

17:45 Panel DiscussionModerator: Niels Kuster

13:00 Brief Overview (Niels Kuster)Sensor Technology (Sven Kühn) Computational Life Sciences (Esra Neufeld)Medical Applications (Myles Capstick)

15:30 Goodbye Drink

SCHEDULE

Special EventsFondue Dinner at Üetliberg on Monday, March 21, 2011 (directly following Session 3)

Updated Program

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