the technology the missing link in biopharmaceutical sciences tm
TRANSCRIPT
Reliable assessment of drug exposure
Single point in time assessment
Continuous assessment over time
Biased •Pill counts •Pharmacy refill data
•Patient diary•Retrospective questionnaire
Reliable •Therapeutic drug monitoring (TDM)
•Electronic monitoring (EM)
Vrijens & Urquhart, 2004 Journal of Antimicrobial Chemotherapy
The MEMS® monitor
The MEMS 6 monitor is an electronic cap that shows the number of openings since the start of the current 24-hour period and of hours elapsed since the last medication event.
• Stores up to 3800 medication events in non-volatile EEPROM memory • Wireless data transfer, • Fits standard pharmacy bottles 38mm-400 thread closure, • Available with or without child resistant security, • Unique serial number identification is indelibly printed on the monitor and stored in its electronic memory, • Waterproof, • CE marked,• 18 months battery life.
Introducing advanced technology on monitoring adherence
Medication Event Monitoring System (MEMS®)
MEMS VI®
Events recording and storage
Communicator MEMS VI®
Communication device
www.viewcompliance.com
Internet
Need a simple but robust taxonomyOur web-based platform
Physician, Pharmacist
Sion, Switzerland
Anonymous, but drug-specific, aggregated database
Individual reports back to Physician, Pharmacist
FDA 21 CFR, 11 & HIPAA compliant
Internet
www.viewcompliance.com
Evolving Technology
• Over 400,000 patients monitored to date with the various version of MEMS (Medication Event Monitoring System)
• Currently used version (MEMS 6) has a proven track record on >140,000 patients
• >15,000 patients from controlled clinical trials with available data
– Data on >3 Million monitoring days
• Ongoing device development:
– MEMS 7 (Wireless)
– Polypharmacy
– Blister packaging
MEMS 6AARDEX®
AARDEX®
AARDEX®