the pros and cons of biotechnology
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Expose' of the good and bad parts of biotechnology.TRANSCRIPT
Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
The Pros and Cons
of
Biotechnology
Long Beach City College, Spring 1999
Bio 25, Biology and Society
Instructor Dr. Jeanne Bohm
By James R. Walker
Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
Introduction
The word biotechnology is a synthesis of two words, really; biology and
technology. As defined by Webster’s unabridged 1979 edition of the dictionary biology
is: (Gr. bios, life and logos, description) the science of life; the branch of science which
investigates the phenomena of animals and plants with regard to their morphology,
physiology, origin, development, distribution, habits etc...: it includes botany, zoology
and their subdivisions. Technology is defined as (techne’, art and logos, description) the
study of practical or industrial arts, applied science. So when we put the two root words
together biotechnology means the practical or industrial application of biology with the
unstated premise being to satisfy human intentions and desires.
This short treatise will discuss the pros and cons of biotechnology. Before we dive
right into the arguments for both sides I think it best to address the unstated premise i.e.
satisfying human intentions and desires. It is here we must stop and ask ourselves what
are the intentions and are they necessarily best for the entire ecosystem we call earth? It is
true that both camps, pro and con, would indubitably maintain that their appeal is best for
earth. However, we must examine all human interventions into the natural order of things
and ask have they produced far reaching and rippling effects beneficial to everything else
on the planet? I think looking at our history will answer this question. I will leave the
reader to ruminate on this thought in his or her own time meanwhile, let’s look at the two
sides of the coin. We will begin with the positive aspects of biotechnology.
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
Biotechnology pros
If we look around us, it is clear that technology is here to stay. Our culture is utterly
dependent on various aspects of it. We could not get through our day without technology.
From clocks to microwaves to transportation systems to VCR’s, our lives are inherently
tied up with technology.
Biotechnology in particular has greatly increased, for many, the quality of life.
We live in greater comfort in various climates. We have abundant food and clean water
supplies, our health has improved and longevity increased. Many diseases now have
treatment or cures and vaccines make us immune to some diseases. Advancements in
biotechnology have increased crop yields, fattened our cattle, identified genes responsible
for various maladies and hints at gene therapy to rectify these maladies. It has enabled us
to create an oil gobbling bacteria to assist us in oil spill clean ups and fabrics which are
antifungal and antibacterial (in Scientific American). For the first time in human history
humankind is wielding and manipulating the very foundations of life itself. It promises a
future in which we are in control of the essence of life to such a degree that we can now
orchestrate evolution itself, specifically human evolution.
Through genetic testing and screening we can determine the health of a baby
while still developing in the womb (amniocentisis), and ascertain the genetic
predisposition for certain diseases and conditions not only of the fetus but of adults as
well (in Exploding the Gene Myth). Cures or therapy for genetic ills are imminent. As
Aaron Wildavsky writes:
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
That honor goes to molecular genetic engineering, which uses recombinant DNA techniques to
transfer specific genes within and across species. What is more, subject to some limitations, genes
may be mutated, rearranged, or produced synthetically and then inserted into the desired host (in
Public Policy).
These accomplishments and masteries constitute a force unprecedented in the history of
the earth, and bears a hope for a future filled with well-being. At long last that terrible
image we all have in the back of our minds, of our predecessors crouched in a cold cave,
sickly, hungry and frightened, can be put to rest forever.
What is the cost of such control? This we will explore in the next section, the cons of
biotechnology.
Biotechnology cons
Food production in America has increased many fold largely due to
biotechnological innovations. Agribusiness raises livestock and crops which produce
more food using various chemicals, steroids and genetic engineering. We are beginning
to feel the backlash of these innovations. In spite of this, corporate agribusiness proclaims
America has the safest, cheapest and most plentiful supply of food in the world.
However, the proliferation of huge factory farms and feed lots spreads blight.
Michael W. Fox has a Ph.D. in medicine and a D.Sc. in ethology/animal behavior
both from London University. Regarding the adversities of using biochemical means to
increase food production he writes:
Can you believe a livestock industry and their technical experts who see nothing wrong with
feeding antibiotics every day to farm animals, knowing the grave risks of antibiotic-resistant
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
bacteria to the consumer public? Agribusiness claims antibiotics are necessary in order to reduce
consumers’ and farmers’ costs because sick animals are less productive and grow slowly,
However, antibiotic—resistant infections are increasing at an alarming rate among humans,
especially among infants, the elderly and those with compromised immune systems (in Eating
with Conscience).
Furthermore, Fox is alarmed by the increasing rate of genetically engineered food and
governmental polices regarding this and asks:
Would you trust any government that refuses to enforce labeling of genetically engineered food
and denies consumers the right to know if any food they buy is not natural? The United States
Federal Drug Administration has refused to enforce such labeling.’ (in Eating with Conscience).
These corporations are producing “designer foods’, composed of synthetic ingredients
and manipulated DNA without fully investigating the environmental and health
ramifications. By manipulating gene pools we are shrinking diversity. Diversity of gene
pools within species insures survival of that species by allowing enough allele variation
which may be more able to cope with changes in environment and parasitic pathogens.
Many crops have such a narrow gene pool that they are totally dependent on human
intervention and maintenance.
We depend heavily on chemical fertilizers and pesticides for our cornucopia but
the run-off of these pollutes our ground water, lakes and streams. Although the United
States addresses this issue with the Clean Water Act, there are serious concerns over lack
of enforcement (in Eating with Conscience). Not only is genetic information used in plant
and animal husbandry, it is used in the realm of human development as well.
The multi-billion dollar Human Genome Initiative is a huge research project to
map every gene on the DNA of a prototypical human being. Grandiose promises of
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
therapeutic benefits are supposed from the project. “They point instead to the real threats
to privacy and civil liberties already resulting from the unregulated increase in genetic
predictions”, states Ruth Hubbard professor of biology emeritus at Harvard University (in
Exploding the Gene Myth). Genetic predictions, whether they involve testing or
screening, are based on the assumption that there is a relatively straightforward
relationship between genes and traits. However, genetic conditions involve a largely
unpredictable interplay of many factors and processes. To quote the authors of a popular
genetics textbook An Introduction to Genetic Analysis:
A gene dose not determine a phenotype (noticeable trait) by acting alone; it does so only in
conjunction with other genes and with the environment. Although geneticists do routinely ascribe
a particular phenotype to an allele of a gene they have identified, we must remember that this is
merely a convenient kind of jargon designed to facilitate genetic analysis. This jargon arises from
the ability of geneticists to isolate individual components of a biological process and to study them
as part of genetic dissection. Although this logical isolation is an essential aspect of genetics, a
gene cannot act by itself.
Even genes that implicated in conditions whose inheritance follows a regular and
predictable pattern are proving to be far from simple to define and localize. For example,
the gene associated with Huntington disease, which is thought to lie on chromosome 4,
has so far resisted precise localization or analysis. In fact, some scientists are beginning
to wonder whether DNA in more than one region of this chromosome may be involved
(in Exploding the Gene Myth). Discrimination may arise from such predictive genetic
screening.
The for-profit health insurance industry raises this issue by several notches.
Insurance companies make money only so long as people pay more to buy health
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
insurance than it costs the insurance company when these people feel so ill that they
consult a physician. So, to make a healthy profit, insurance companies should sell most of
their insurance to people who won’t get sick. Not only will this not cure or prevent the
conditions, it will create a new group of stigmatized people, the “asymptomatic” or
“healthy ill’ who, though they have no symptoms, are considered likely to have a
particular disability at some point in the future. Job applicants may experience similar
screening as well.
As always, the discriminatory potential will not be felt equally in all applicants. A
highly skilled person with unique qualifications will be less likely to be screened out than
a applicant for a more routine job, for which many others could be hired. So here as
elsewhere, the least powerful segments of society are most likely to be exposed to
discrimination.
We need strong laws at the federal level to control genetic discrimination in
employment and insurance. Scientists involved in predictive genetics and the Human
Genome Project have promised that genetic predictions will improve preventive measures
and so make us healthier. However, if insurance companies can use results of genetic
tests to limit or deny coverage, such predictions will have the opposite effect. Without
coverage, people will have less access to preventive care, thus will be more likely to
become ill and less able to get appropriate medical treatments. Since much of the
scientific research that can lead to genetic discrimination is being done in this country,
Americans have a special responsibility to develop ways to counteract this insidious new
form of discrimination. I hope that scientists will join in the effort, and devote as much
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
energy to preventing genetic discrimination as they do to developing the technologies that
make such discrimination possible.
Humans have always found ways to intervene in nature. The ability to make a fire
and the invention of the wheel had profound impacts on the development of human
society. The domestication of plants and animals allowed humans to live in ways
unthought-of before. The rise of modern science and the industrial revolution stand as
markers of yet another major change in our way of life.
Our current technological revolution presents further opportunities and capacities
for intervening in life on both the micro and macro levels. The technologies surrounding
conception and birth, such as in vitro fertilization and amniocentisis, help determine
when we will be born and what some of our qualities may (or may not) be. Developments
in genetics led to production of new grains that produce more bushels per acre. An oil
eating bacterium has been manufactured to help clean up oil spills. And while a totally
implantable artificial heart is not yet a reality, various assist devices are available to serve
as a transition technology. The Human Genome Project will give us a map of the genetic
structure of the human body and serve as a basis for new approaches to treating genetic
diseases and defects. Hardly an area of our lives is not touched by biotechnology. But the
record of technology is certainly a mixed one. Clearly biotechnology has brought
benefits. But serious issues of privacy and confidentiality are being raised because of the
vast amounts of information about individuals being collected and stored. In addition,
many wonder whether such technologies reduce people to commodities (in An
Introduction to Bioethics). Whatever one’s judgment, biotechnology is here to stay and
will continue to have far-reaching effects on our lives.
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
I will end this discourse with a quote from the late great Carl Sagan:
We are at a crossroads in human history. Never before has there been a moment so simultaneously
perilous and promising. We are the first species to have taken our evolution into our own hands.
For the first time we possess the means for intentional or inadvertent self—destruction. We also
have, I believe, the means for passing through this stage of technological adolescence into a long-
lived, rich and fulfilling maturity for all the members of our species. But there is not much time to
determine to which fork of the road we are committing our children and our future (in Broca’s
Brain).
Works Cited
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Bio 25, Biology and Society, Long Beach City College, Spring 1999, Instructor Dr. Jeanne Bohm
By James R. Walker
Fox, Michael W. Eating with Conscience. Oregon: New Sage Press, (1997).
Hubbard, Ruth and Wald, Elijah. Exploding the Gene Myth. Boston: Beacon Press,
(1993).
Sagan, Carl Broca’s Brain. New York: Ballantine Books, (1997).
Shannon, Thomas A. Introduction to Bioethics. New Jersey: Paulist Press, (1997).
Siegel, Richard W. “Creating Nanophase Materials.” Scientific American volume 275,
number 6, (1996).
Suzuki, David T., Griffiths, Anthony J.F., Miller, Jeffrey, and Lewontin, Richard C.
Introduction to Genetic Analysis. New York: W. H. Freeman and Company, (1989).
Wildavsky, Aaron Public Policy. Class handout.
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