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The process of Evaluation Timeliness of Outbreak Detection and Response in SEE Region Kujtim Mersini, Jonilda Sulo, Ledia Agolli, AdelaVasili, Sanjin Musa, Goran Cerkez, Angel Kunchev, Armend Iseni, Vladimir Mikikj, Vesna Stefanovska, Isme Humolli, Arijana Kalaveshi, Borna Plese, Daniel Cohen, James Crilly, Silvia Bino

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Page 1: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

The process of Evaluation

Timeliness of Outbreak Detection

and Response in SEE Region

Kujtim Mersini, Jonilda Sulo, Ledia Agolli, AdelaVasili, Sanjin Musa,

Goran Cerkez, Angel Kunchev, Armend Iseni, Vladimir Mikikj, Vesna

Stefanovska, Isme Humolli, Arijana Kalaveshi, Borna Plese, Daniel Cohen,

James Crilly, Silvia Bino

Page 2: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Dt of Disease Detection Disease Reported Nationally Disease Treatment Disease Treatment

7642

DD

S

DD

D

DD

R_

N

DD

T

DD

T

DD

R_

L

DLR

Date of Disease Detection is

considered as patient visit date

to medical facility or general

practitioners when the disease is

suspected.

Date of Disease Reported

Nationally is considered as the

date that the disease is reported

to national public health

authorities.

Date of Disease Treatment is

considered as the starting date of

a specific treatment for the

infectious disease

Date of Disease Treatment is

considered as the starting date of

a specific treatment for the

infectious disease

Date of Disease Start is

considered as the patient

symptom onset date.

Dt. of Disease Start

Date of Disease Reported Locally

is considered as the date that the

disease is reported to local public

health authorities.

Disease Reported Locally

Date of Laboratory Result is

considered as the date of

laboratory confirmation of the

disease.

Patient Hospitalization is

considered the date when the

patient was hospitalized

independently if the disease was

diagnosed or not.

DP

H

Date of Disease End is considered

the date the patient has

recovered or died.

DD

E

Laboratory Result Patient Hospitalization Disease End

Page 3: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Outbreak Time Lags

• Date of Outbreak Investigation

• Date of Outbreak Control

• Date of Outbreak End

• Date of Public Communication

• Date of Cros-Border Notification

• Date of Notification to IHR

Page 4: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Auxiliary Data

• Case Classification

• Case Succession

• Total Outbreak Cases

• Total Confirmed Cases

• Total Probable Cases

• Total Suspect Cases

• Number of Deaths

• Population at Risk

Page 5: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Summary Summary Summary Summary

•5 countries

•10 priority diseases

•63 outbreaks

•6021 cases

Page 6: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,
Page 7: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,
Page 8: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,
Page 9: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,
Page 10: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

0 10 20 30 40

DDD_DDS DLR_DDS

DDT_DDS DPH_DDS

DDE_DDS

Page 11: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

-10 0 10 20

DDD_DDS DDRL_DDD

DDRL_DRN DLR_DDRN

DPH_DLR DDE_DDH

Page 12: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

0 50 100 150 200

DOE_DOS DOI_DOS

DOC_DOS DOR_N_DOS

Page 13: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Disease: BRUCELLOSIS, Country: KOSOVO, n=172

0 50 100 150 200 250

Onset of symptoms till diagnosis (days)

0

10

20

30

40

50

60

70

80

90

100

Cu

mu

lative

dis

trib

utio

n (

%)

Page 14: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Disease: TULARAEMIA, Country: KOSOVO, n=540

0 10 20 30 40 50 60 70 80 90 100

Onset of symptoms till diagnosis (days)

0

10

20

30

40

50

60

70

80

90

100

Cu

mula

tive d

istr

ibution (

%)

Page 15: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Disease: BRUCELLOSIS, TULARAEMIA, Country: KOSOVO, n=172, 540

0 10 20 30 40 50 60 70 80 90100

110120

130140

150

Onset of symptoms till diagnosis (days)

0

10

20

30

40

50

60

70

80

90

100

Cu

mu

lative

dis

trib

utio

n (

%)

BRUCTUL

Page 16: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

DISEASE: TULARAEMIA, COUNTRY: KOSOVO, n=540, 542

0.501.00

2.004.00

8.0016.00

32.0064.00

128.00

256.00

512.00

Onset of symptoms till diagnoisis and reporting (days)

0

10

20

30

40

50

60

70

80

90

100

Cu

mu

lative

dis

trib

utio

n (

%)

KTSTRKTSTD2

Page 17: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,
Page 18: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Acknowledgements

Colleagues form country teams for all the hard work

SGTF for funding this work and continuous support

Page 19: The Process of Evaluation Timeliness of Outbreak Detection …€¦ ·  · 2018-02-22The process of Evaluation Timeliness of Outbreak Detection and Response in SEE ... Vladimir Mikikj,

Thank you