the neurology of wine

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The Neurology of Wine Andrew Hodson MB. ChB. MRCP, DCH. Proprietor of Veritas Winery

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The Neurology of Wine, a guide to the evolution of the brain, the relation to the Limbric System, How nerve cells in the brain are affected by Alcohol and the effects of Alcohol on Behavior, Brain Neurotransmitters and Neuronal Cell Membranes

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Page 1: The Neurology of Wine

The Neurology of Wine

Andrew Hodson MB. ChB. MRCP, DCH. Proprietor of Veritas Winery

Page 2: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain makes Homo Sapiens Homo Sapiens.

The human brain is uniquely sensitive to the effects of wine.

Page 3: The Neurology of Wine

The Neurology of WinePhylogogeny of the Brain

Page 4: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain is what makes the Sapiens part of Homo Sapiens

Page 5: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain is what makes the Sapiens part of Homo Sapiens

Page 6: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain is what makes the Sapiens part of Homo Sapiens

Page 7: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain is what makes the Sapiens part of Homo Sapiens

Page 8: The Neurology of Wine

The Neurology of Wine

Archipallium Vegetative function Survival reflexes Reproduction

Paleopallium Limbic System Emotion Memory

Neopallium Language Cognition Rationality

Page 9: The Neurology of Wine

The Neurology of Wine

The evolution of the human brain The Limbic System – The Center of Emotions

IntelligenceSmellTasteHungerThirstSexualityMemoryEmotion

Page 10: The Neurology of Wine

The Neurology of WineThe evolution of the human brain –The Limbic System

NeocortexEntorhinal CortexHippocampusThalamusHypothalamusCingulate Gyrus Septal NucleiiMammilary Bodies

IntelligenceSmellTasteHungerThirstSexualityMemoryEmotion

Page 11: The Neurology of Wine

The Neurology of WineThe evolution of the human brain –The Limbic System

LanguageMemory

IntelligenceEmotionHumor

Wine VisionTasteSmell

SensationMusic

Art Romance

Dance Tradition

Page 12: The Neurology of Wine

The Neurology of WineNeurophysiology of the Brain

SynapseNeurotransmitter

Nerve Cell - Neuron

Page 13: The Neurology of Wine

The Neurology of WineHow Nerve Cells Communicate

NEUROTRANSMITTERS - Neuromodulation

Excitatory Monoamines Dopamine Epinephrine Serotonin Histamine

Acetyl CholineEndorphins

Inhibitory Gama Amino Butyric Acid GABA

Page 14: The Neurology of Wine

The Neurology of WineThe Four Humors

Page 15: The Neurology of Wine

The Neurology of Wine

Phlegm Yellow Bile

Blood Black Bile

GABA

Dopamine Serotonin

Glutamate

Page 16: The Neurology of Wine

The Neurology of WineThe evolution of the human brain Neurotransmitters

Page 17: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on:Behavior

Brain Neurotransmitters Neuronal Cell Membranes

Page 18: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on:Brain Neurotransmitters

Dopamine- excitation- cocaine and amphetamines GABA – calm, sleep, less anxiety - valium

Glutamate - loss balance, slurring - chloroform Endorphins –euphoria, less pain - opiates

If Morphine is a scalpel alcohol is a hand grenade.

Page 19: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on Behavior

Two gallons of wine is a lot of wine even for two paisanos. Spiritually the jugs may graduated thus

1) serious and concentrated conversation 2) Sweetly sad memory 3) More thoughts of old and satisfactory loves 4) General and undirected sadness 5) Black unholy despondency 6) A song of death and longing

7) Every other song each one knows. John Steinbeck

Page 20: The Neurology of Wine

The Neurology of Wine

Effect of Alcohol on Behavior vior

Page 21: The Neurology of Wine

The Neurology of Wine

Effect of Alcohol on Behavior

Page 22: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on:Brain Neurotransmitters

Dopamine- excitation like cocaine and amphetamines GABA – calm, sleep, less anxiety like valium

Glutamate - loss balance, slurring like chloroform Endorphins –euphoria, less pain like opiates

If Morphine is a scalpel alcohol is a hand grenade.

Page 23: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on:N Neuronal Cell Membrane

Page 24: The Neurology of Wine

The Neurology of Wine

The Effect of Alcohol on the Neuronal Cell

Membrane: Voltage – Gated Channels

Page 25: The Neurology of Wine

The Neurology of Wine

Page 26: The Neurology of Wine

The Neurology of Wine

Page 27: The Neurology of Wine

The evolution of the human brain

The Neurology of Wine

We also have urns if you would like to think out of the box

Page 28: The Neurology of Wine

The Neurology of Wine

Chronic effects of Alcohol on the Brain

Page 29: The Neurology of Wine

The Neurology of Wine

Effect of Alcohol on Behavior