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THE MCGILL UNIVERSITY

RESEARCH CENTRE FOR STUDIES IN AGING (MCSA)

NOVEMBER 2018

THANK YOU PARTICIPANTS!!

A special thank you to all of our participants, sponsors, kiosk representatives, who attended and supported our Health Day – Open House and Symposium, “Aging in the 21

st

Century.“

HEALTH DAY – OPEN HOUSE FRIDAY, SEPTEMBER 21, 2018

9:00- 4:00 PM

Dr. Pedro Rosa-Neto, Director of MCSA, with participants on September 21, 2018.

Dr. Paolo Vitali, MD, PhD, FRCPC and Marianne Provencher. “Language Assessement”.

Speaker: Laura Robb, Genetic Counselor “Genetics, Health & Me!”

On September

21, 2018, MCSA held it’s 3rd

Open House event for Montreal community members. A total of 85 participants, staff members and speakers joined in this year’s event. This year, the event was held at both MCSA and CrossRoads Pavilions. Participants were invited to register and attend various health stations to evaluate: “Memory”, “Oral Health”, “Vital Signs”, and “Language Assessment.” They also attended all of the knowledge transfer (KT) lectures such as: “Genetics, Health & Me!”, “Arthritis & Nutrition”, “Women’s and Men’s Health”, “Managing Stress in Caregiving”, “Osteoporosis”, “Healthy Eyes”, “New Frontiers in Alzheimer’s Disease Research,” and “Love, Sexuality & Aging.” Crossroads Pavillion Staff

Speaker: Mélanie Le Berre, MSc, PT “Love, Sexuality & Aging.”

Speaker: Dr. Chris Serhan, Optometrist “Healthy Eyes.”

Speaker: Mina Mirtaheri, Dietetics Faculty of McGill University “Arthritis & Nutrition.”

Welcome to the 6th edition of our Newsletter, keeping you updated on the latest news, events and research information.

Speaker: Joseph Therriault, B.Sc. “New Frontiers in Alzheimer’s Disease Research.”

Dr. Michael Wiseman, DDS, Associate Professor, Faculty of Medicine, Associate MCSA Member – “Oral Health”

Symposium Friday, October 5, 2018 Aging in the 21st Century

Douglas Hall, Douglas Mental Health University Institute.

The McGill University Research Centre for Studies in Aging Education Committee, in collaboration with Alzheimer Society Montreal and Alzheimer Groupe Inc., hosted a Symposium in honor of “International Seniors Day”, on October 5, 2018. Over 130 participants, staff members and kiosk representatives attended our Symposium entitled: “Aging in the 21

st

Century.” Mr. Patrick Murphy -Lavallée

Dr. Dolly Dastoor, Chair of the MCSA Education Committee had the pleasure of introducing our keynote speaker Mr. Patrick Murphy-Lavallée: currently the Director of the Support for Elderly Autonomy Program Seniors at the Montreal West Island IUHSSC, has for the past 25 years, strived to improve the quality of services and their integration, particularly for the most vulnerable clients of the health and social services network. Four lectures were presented, which focused on positive aspects of aging and 11 kiosks displayed their services as well as provided valuable information and resources to all participants.

Dr. Serge Gauthier, C.M., C.Q., MD, FRCPC “Status of Research on Prevention and Treatment of Alzheimer’s Disease.”

Dr. Nathalie Bier, Ph.D, OT “Home Care for Older People with Cognitive Impairment: What is the Potential of New Technologies.”

Dr. Patricia Belchior, Ph.D, OT (c)

“Engaging your Brain: An Occupational –

Based Approach for Healthy Aging.”

Dr. Marc Roig, Ph. D “Exercise and Memory: Timing Matters.”

Camille N. Isaacs-Morell, BA, MBA, Executive Director, Alzheimer Society of Montreal, Dr. D. Dastoor, PhD, Dr. S. Gauthier, C.M., C.Q., MD, FRCPC, Dr. M. Wiseman, DDS, Linda Israel, Executive Director, AGI Alzheimer Groupe Inc., Mr. Patrick Murphy-Lavallée, Dr. L. Mazzella-Maiolo, MD, FRCPC, S. Aguzzi, MCSA Administrative Assistant, Maria Maiolo, RN, Alexandra Triantafillopoulos, MCSA Business Development.

Kiosks

Alzheimer Society Montreal

Alzheimer Groupe Inc.

McGill University – School of Continuing Studies, McGill Community for Lifelong

Learning.

Philips Lifeline

ACT Inc. - Autonomy Community Therapy

Lobe – Cliniques en Santée Auditive et Communication

CBI Home Health – We Care

Expedia Centre de Croisière

Éducaloi – Information Empowers

REISA – The East Island Network for English Language Services.

Les Services Gérontologiques Monique Renaud Inc.

MCSA & CrossRoads Team: Tamar Tatigian, Karen Wan, Ellie Joung, Jenna Stevenson, Dr. Dolly Dastoor, Carley Mayhew, Sarah Sbeiti, Silvana Aguzzi and Alexandra Triantafillopoulos.

Testimonials from participants included a deep appreciation for speaker presentations, informative kiosks and organization of the Symposium. Camille N. Isaacs-Morell, BA, MBA, Executive Director, Alzheimer Society Montreal, quoted: “There was an impressive level of expertise at the Symposium, from the speakers and in the kiosks, which greatly benefited all participants.” Meghan Williams, MSW, Director of Support Services, Alzheimer Groupe Inc. (AGI), quoted: “MCSA Team paid attention to every detail and everyone was in a wonderful welcoming mood and I was pleased to see so many new faces and very impressed on how many participants stayed until the very end.”

Yvonne Quintyn, Cruise & Vacation Consultant, Expedia Cruiseship Centres, DDO - Winner of Raffle Prize sponsored by:

SPONSORS A special thank you to all our sponsors:

October 15, 2018 - MCSA PRESENTS “THE 1

st LAURA CHALK ROWLES

LECTURESHIP IN DEMENTIA.” Lecture: Amyloid Imaging: Influence of Very Advanced Age and Genetic Alterations.” Speaker: Dr. William E. Klunk MD, Ph.D. Location: Montreal Neurological Institute and Hospital.

Dr. William E. Klunk, MD, PhD is Director of the Laboratory of Molecular Neuropharmacology and Co-Director of the Alzheimer’s Disease Research Center at Pittsburgh University. Professor Klunk is one of the world’s leading experts in the early detection of Alzheimer’s Disease and is a pioneer in the field of in vivo amyloid imaging in humans. In 2001, in collaboration with Dr. Chet Mathis, Dr. Klunk created a molecule that could be used to image Alzheimer’s Disease pathology by tagging amyloid (PiB); it was one of few eureka moments so far in Alzheimer’s Disease research. With PiB, Dr. Klunk changed the history of the neuroimaging in Alzheimer’s Disease, allowing for the first time a non-invasive quantification of brain pathology in vivo, which was considerate as a single most important advance in the history of imaging in neurodegenerative conditions. (Adapted from: William Klunk: imaging Alzheimer’s disease in vivo; The Lancet of neurology 2015). Now, in the 15th

anniversary of the publication showing the first results in vivo subjects using PiB, Dr. Klunk came to Montreal to talk about

the developments of his discovery. Dr. S. Gauthier presented the 1

st Laura

Chalk Rowles Lectureship in Dementia Award, to Dr. William E. Klunk on October 15, 2018, in recognition of his outstanding contributions in the field of imaging dementias.

8th McGill University Health Fair for Faculty and Staff

October 26, 2018

On October 26, 2018, McGill University held its 8

th Annual Health Fair. MCSA, organized a

colorful and interactive kiosk among 35 other exhibitors. The following staff/research members presented: Jordan Lecourtois presented the updated version of P.O.N.D.E.R.; Cécile Tissot, engaged participants with various memory tests; Margaret De Chazal, RN and Carley Mayhew, RN, helped individuals who wanted their blood pressure and blood sugar levels checked. Participants ranging from ages 40+ were interested in the information that was disseminated by Alexandra Triantafillopoulos. Participants were also delighted to find out about our Centre’s medical services and on-going research developments.

Cécile Tissot, Jordan Lecourtois, Carley Mayhew, Margaret De Chazal, and Alexandra Triantafillopoulos

Handicap-Vie-Dignité

On October 24, 2018, McGill Research Centre for Studies in Aging, participated in a conference entitled “Together...promoting quality of rights of residents/HVD bilingual conference on the rights of residents and how to advocate for them in public long term care settings,” organized by the non-profit organization Handicap Vie Dignité, sponsored by the Hélène Rumak Fund. MCSA had an interactive kiosk to promote Centre’s services, disseminated information on age related topics and had the opportunity to participate in two workshops.

The conference focused on the rights of residents and how to advocate for them in public long term care residences. The target participants were residents, family caregivers and personnel. This conference hosted excellent speakers and panelists led by Johanne Ravenda, President of HVD which she cofounded with the late Hélène Rumak. Opening remarks were given by video by Marie Beaulieu, PhD. and Chairholder of the Research Chair on mistreatment of Older Adults at the Université de Sherbrooke. The panel was organized and animated by MCSA`s affiliate member and vice president of HVD Daphne Nahmiash, PhD. and Maître Christine Morin Chairholder of the Antoine Turmel on Legal Protection for the Elderly from the Faculty of Law of Laval University. The afternoon was followed by eight training workshops including one by Marie Eve Bedard, PhD. From her recent doctoral thesis, on « La portée et les limites des actions des comités des usagers dans les traitements des situations de maltraitance envers les

personnes aînées ou vulnérables. » (The scope and limits of users’ committees when addressing situations of mistreatment of older or vulnerable adults). Recommendations from the 8 training workshops were made and will be presented shortly to the Minister of Seniors. The web diffusion of the conference will be available soon at the following link: http://handicapviedignite.ca/fr-ca/Conf%C3%A9rence-HVD-2018#webdiffusion

Associazione Spignese di Montreal 2nd Annual Alzheimer Fundraiser Event – Oct. 20, 2018

RAISED $11,725.00

Associazione Spignese di Montreal, held their 2nd Annual Alzheimer’s Fundraiser on Saturday, October 20, 2018 at Ritz Reception Hall, Montreal, donating all profits to the McGill University Research Centre for Studies in Aging. Over 230 guests attended the fundraiser. Dr. Pedro Rosa-Neto, MD, PhD, Director of MCSA and Dr. Paolo Vitali, MD, Ph.D, FRCPC were the guest speakers at the gala evening. On behalf of MCSA, we would like to thank the Committee Members and the President of the Association Spignese di Montreal for organizing this event. We are humbled by the generosity of the Association and we would like to extend our deepest gratitude.

CONFERENCES & COURSES 2018

Dr. Muhammad Naveed Iqbal Qureshi, PhD, who recently joined MCSA on June 20, 2018 as a postdoctoral research fellow attended the “Sixth Biennial Conference on Resting State and Brain Connectivity”, from September 24 to 29, 2018. The Conference took place in Montreal and was hosted by the Centre Mont Royal Conference and Special Events Centre.

Conference: Clinical Trials on Alzheimer's Disease 2018 (CTAD2018) Oct. 24-27th, 2018 Barcelona, Spain

October 27, 2018 - Min Su (Peter) Kang presented: “First Longitudinal Evaluation of the Tau Tracer [18F]MK-6240 for the use in clinical trials.”

One of the hallmarks of Alzheimer's Disease is neurofibrillary tangles and it is thought to greatly influence memory and cognitive decline. We presented innovative methods to sensitively measure early changes in neurofibrillary tangles in patients with Alzheimer's Disease. With our first 1-year data in neurofibrillary tangles changes using [18F]MK6240 PET tracer, we reported an optimal way to analyze the data. Together with a new approach to unveil the potential power of the data, we showed that it dramatically improves the power in detecting

therapeutic effects in the clinical trials.

MEMORY CLINIC: ALZHEIMER’S DISEASE RESEARCH UNIT

Alzheimer’s Disease Research Unit Director Dr. Serge Gauthier and Dr. Pedro Rosa-Neto, Director of the McGill University Research Centre for Studies in Aging, utilize the best clinical practices and cutting-edge technologies for diagnosis of medical conditions associated with memory problems. The Memory Clinic is actively involved in cognitive research and is recognized internationally as a Clinical Trial Site. Clinical trials (Phase II-IV) that test the efficacy and safety of experimental drugs for AD and other cognitive disorders are ongoing. The MCSA is in the process of recruiting for 3 different clinical trials on Alzheimer’s Disease. Our team will answer all questions in regards to clinical trials and if you are interested in obtaining more information and/or participating in one of our clinical trials please do not hesitate to contact Tamar Tatigian at 514-761-6131 x6314 or email: info.mcsa@mcgill.ca.

DONATIONS We appreciate your continued support to our Centre! To achieve all of our objectives and to continue to play an important role in aging research in Quebec and Canada, we always need your help. In order to (1) advance in our mission and mandate towards prevention, (2) our major focus of aging research, and (3) our commitment in investigating causes and new treatments of the dementias, we count on your continued support. We thank all of our Donors for their encouragement and confidence in our work which contributes to the preservation of the highest levels of research, education, and teaching in the field of aging. We are happy to accept donations that will support our research efforts. We will issue a receipt for tax purposes for all donations above $15.00. In addition, every donor whose gifts exceed $500 will be honored by receiving a permanent inscription on our Donor Wall. If you would like to make a donation by mail, phone or email, please contact Alexandra Triantafillopoulos at 514- 761-6131 X 6311 or By Email: alexandra.triantafillopoulos1@mcgill.ca or silvana.aguzzi@mcgill.ca. As the holidays approach, we would like to express our deepest gratitude to all of our Donors and are grateful for your continuous support and interest in the Centre’ research and knowledge outreach programs. Thanks to Donor’s like you we can continue our mission in investigating causes and treatments of the dementias, especially Alzheimer Disease. Your support is extremely important to us and we encourage you to spread the word on social media in helping with our cause. Dr. Pedro Rosa-Neto, Director of the McGill University Research Centre for Studies in Aging, Dr. Serge Gauthier, Director of the Alzheimer Disease Research Unit/Memory Clinic and the MCSA Team would like to thank you for your generous contributions and support throughout 2018. We would like to wish you and your families a Happy Holiday Season and a Peaceful New Year!

In addition, we hope that you will be able to take part in one or more of our many exciting events planned for 2019; such as our Brainy Boomer Lecture Series and the Annual Donor BBQ for Donors & Friends. We look forward to your feedback and suggestions, email us at info.mcsa@mcgill.ca.

www.mcsa.ca www.aging.mcgill.ca tnl.research.mcgill.ca

http://alzheimer.mcgill.ca

UPCOMING EVENTS SAVE THE DATE 2018-2019

BRAINY BOOMER LECTURE SERIES

“Healthy Body – Healthy Bones” Wednesday, November 7, 2018

Time: 2:30- 4:00 Dr. Loraine Mazzella-Maiolo, MD, FCCP(c)

The Teapot 2901 St Joseph, Lachine, Qc H8S 4B7

Registration: T: 514-637-5627

“Cardivascular Health and Nutrition” Thursday, November 8, 2018

Time: 1:30-3:30 Mina Mirtaheri, Dietician with McGill

University Stagier Ms. Victoria Chu The Teapot

2901 St Joseph, Lachine, Qc H8S 4B7 Registration: T: 514-637-5627

“Aging Successfully” Wednesday, November 21, 2018

Time: 1:00-4:00 Dr. Dolly Dastoor, PhD

DDO Seniors Club –Centre Communautaire 1200 boul. de Salaberry,

Dollard des Ormeaux, Quebec H9B 2A7 Registration: T: 514-684-1012 x209

“Myths of Alzheimer’s Disease “ Thursday, November 29, 2018

Time: 1:30 – 3:30 Dr. Dolly Dastoor, PhD

The Teapot 2901 St Joseph, Lachine, Qc H8S 4B7

Registration: T: 514-637-5627

“Your Smile …… Healthy for Life!” Wednesday, December 12, 2018

Time: 1:30-3:30 Dr. Michael Wiseman, DDS

The Teapot 2901 St Joseph, Lachine, Qc H8S 4B7

Registration: T: 514-637-5627

“Update on Diagnosis and Treatment of Alzheimer’s Disease through its Stage”

Wednesday, January 30, 2019 Dr. Serge Gauthier, C.M., C.Q., MD, FRCPC

Time: 2:00-3:30 Eleanor London Cote Saint-Luc Public Library

5851 Boul. Cavendish Boulevard Cote St. Luc, Quebec H4W 2X8

Registration: T: 514-485-6900 X4205