J. Pathol. 188: 338–339 (1999)

allowing one to down-load references with ease. I must state,however, that when I conducted a search for bcl-2 or bcl-2protein I drew a blank. I wondered if this was because I had touse italics, but since I couldn’t work out how to do this I triedt(14;18) instead and again drew a blank. I remain unsurewhether this is due to the fact that the programe onlyrecognizes indexed words, or to my own inexpertise withcomputers. Nevertheless, one of the main strengths of thisfascicle is the high quality of the illustrations. Their availabilityon CD-ROM provides a valuable treaching and learning aid.

D. H. WSouthampton General Hospital,

Southampton

Diagnostic Histopathology of the Lymph Node.J A. S. Oxford University Press, New York,

1998.

The title of this book suggests a bench-top manual, but inthe preface the author gives his aim as an ‘introduction andguide to interpretation of the lymph node’. These are, to mymind, two different aims, so I’ll bear them in mind in myreview.

The book is of a novel size and is nicely produced, witheasy-to-read typefont. The photographic reproduction is onlyadequate by modern standards and may well not be doingjustice to the author’s originals. This is a serious drawbacktoday in a bench-top manual.

I was introduced to histopathology by an American pathol-ogist who instilled into me the importance of low-powermicroscopy. I’ve always found this helpful, if not essential, inlymph node diagnosis. So far as I can see, Dr Strauchen doesnot share this view, as very few of his photomicrographs arelow powers. Instead, the majority are medium and highpowers. The trouble is that they then all look the same to theintroductory reader and the lack of a range of magnificationsdiminishes the book’s value to the bench-topper.

The text is a good and easy read, taking about 6–7 hourscover to cover. Bench-toppers are notorious wallpaper match-ers, so this will not attract them, given my comments on the

The Lymphoproliferative Disorders. Handbook of Diagnosis,Investigation and Management.J. A. C, A. S. J and G. J. M. Chapman and

Hall Medical, London, 1998. No. of pages: 398. ISBN: 0 41258030 6.

This book claims to be a comprehensive but accessible guideto the current practice and new developments in the study oflymphoproliferative disease. The book is divided into twoparts. The first gives an overview of the normal lymphoidsystem followed by accounts of the principles and basicmethods of laboratory diagnosis, imaging techniques, andtherapy. Lymphoproliferative disorders, mainly as definedin the REAL Classification, are presented in a systematicfashion in Part 2. The book is directed to trainees in haema-tology, pathology, and oncology, as well as being a referencesource for practising clinicians and researchers. It may bedifficult to satisfy such a broad readership with a single book,although Part 1 does give a good overview of the subjectscovered.

It is difficult for me to judge whether the book will be ofvalue to oncologists. Part 2, which would be of most interest topathologists, suffers from being slightly idiosyncratic in style,the references are selective, and the majority of the illustrationsare in black and white and are of variable quality. This bookdoes have the advantage of being one of the first to use theREAL Classification but I doubt if that will compensate in theeyes of pathologists for the lack for detailed description, closereferencing, and good illustrations as found, for example, inthe AFIP Atlas Tumors of the Lymph Nodes and Spleen.

I would not recommend this book as the first or onlypurchase for trainees or consultant histopathologists. How-ever, the authors are very experienced in their fields andthe book would be of value to haematopathologists andresearchers in this field as a quick reference source fortechniques, diagnostic strategies, and management.

D. H. WSouthampton General Hospital,

Southampton

Tumors of the Lymph Nodes and Spleen, AtlaPathology, Third Series. Fascicle 14.CD-ROM version. R A. W, L

J K. C. C, M L. CD. AFIP, Washington, DC, 1997ISBN: 1 881041 33 6 (CD-ROM).

I reviewed this fascicle in 1996 (Journal of179: 221), labelling it an ‘outstanding publiccriticism at that time was that the authors uFormulation, despite the fact that three of thof the group that produced the REAL Clfascicle is now available as a CD-ROM. Whehas any advantages will depend on circumavailability of suitable play-back equipmentmost pathologists would find the book morethe CD-ROM does has some advantages. I paability to expand the illustrations to fill thescreen. This would make the CD-ROM veruseful for those wishing to conduct tutorialssearch facilities on the CD-ROM are also

CCC 0022–3417/99/080338–02$17.50Copyright ? 1999 John Wiley & Sons, Ltd.

BOOK REVIEWS

s of Tumor

M. W, R F.. Price: $65.00.

Pathology 1996;ation’. My only

sed the Workingem are membersassification. Thether this formatstances and the. I suspect thatconvenient, but

rticularly like thewhole computersion particularlyfor trainees. The

an advantage,

figures. For the trainee, it does provide a useful overview,though it’s too much for them unless they happen to know thatthey want to specialize in haematopathology. In which case,they would probably do better with a bench-top manualanyway. In my own practice I use the current AFIP manual ontumors of the lymph nodes and spleen by Warnke et al., 1995.

Note added in proof. Since submitting this review I have beenusing this book in conjunction with my regular textbooks. Iwould therefore like to add that for reactive lymphadenopathyit is very good, at least as good as anything else on the market.

K. GJohn Radcliffe Hospital,

Oxford

Manual of Diagnostic Antibodies for ImmunohistologyA S.-Y. L, K C and F. J W.-M.

L. Greenwich Medical Media Ltd., London, 1999.Distributed worldwide by Oxford University Press. No. ofpages: 385. ISBN: 1 900151 316.

Recent years have witnessed an ever-increasing expansion inthe number of commercially available antibodies which can be