The Kidd Blood Group System in Caucasians BRUCE CHOWN, MARION LEWIS, AND HIROKO KAITA

From the Department of Paediatrics, University of Manitoba and Rh Laboratory, Winnipeg

The calculated gene frquendcn for 1,296 unrc- lated Caucasian adults teated with anti-pa and

dirtribution of 500 ma- and the 1,?l8!5 children derived therefrom is in agreement with expectation bwd on theme frcquenaa

THIS paper reports our observations on the distribution and inheritance of the Kidd blood groups in a Caucasian popula- tion. The data comprise 1) 500 unrelated families and 2) 576 unrelated adults al- ready reported.1 The sera and methods used were those already describedl save for the substitution of anti-Jkb (Kan) for anti-Jkb (Kni/B) about halfway through the study.

The phenotype distributions and the cal- culated gene frequencies for the unrelated adults are set out in Table 1. The new

anti-pb M: ]b 31155, Jkb .W. The phenotype

Work supported in part by the National Founda-

Postal address: Rh Laboratory, 735 Notre Dame tion and in part by NIH Grant HD00527.

Ave., Winnipeg 3. Canada. Received &publication April 12. 1965; accepted

May 20, 1965.

series is made up of those parents from the 500 families not included in the old series. Each series is internally consistent, the x8 values being: for the old 0.298, for the new 0.68 and for the total 0.06. The pheno- type distributions in the old and the new series do not differ ( ~ 2 = 1.54).

The results for the 500 families are set out in Table 2. They are in agreement with expectation; the gene frequencies used to determine the expected numbers in the matings types were ]KO .51155, J k b -48845.

References 1. Chown, B., M. Lewis, H. Kaita. and S. Philipps:

Some blood group frequencies in a Cau- casian population. Vox Sang. 2k378, 1963.

Bruce Chown, M.D., Professor, University of

Marion Lewis, B.A., Lecturer, University of Mani-

Hiroko Kaita. Senior Research Associate, Rh

Manitoba.

toba.

Laboratory, Winnipeg, Canada.

TAnm 1. Kidd Blood Croups in a Caucasian Population ~~

Old Series New Series Total

Obs f iP Obs EXP Obs EXP

Jk (a+b-) 159 155.72 Jk (a+b+) 281 287.54

136 132.74 Jk (a-b+)

576 576.00 - -

Gene frequencies W .5 1 w5 J k b .48005

178 18353 37 1 359.93 171 176.54

720 7M.M - -

~

337 339.16 652 647.61 307 309.23

1 .“!I6 1,296.00 -

.50.185

.495 15

.5 1 155

.48845

506

507 KIDD BLOOD GROUPS

TABLE 2. Distribution of the Kidd Groups in 500 Caucasian Families

Matings Children Number J k (a+b-) J k (a+b+) Jk (a-h+)

Type Obs Exp Obs Exp Obs Exp Obs Exp ‘I

Jk(a+b-) x Jk(a+b-) 36 34.25 102 102 0 0 0 0 102 Jk(a+b-) x Jk(a+b+) 116 130.75 165 158.5 152 158.5 0 0 317 Jk(a+b-) x Jk(a-b+) 61 62.45 0 0 198 198 0 0 198 Jk(a+b+) x Jk(a+b+) 133 124.85 83 88 176 176 93 88 352

Jk(a+b+) x Jk(a-b+) 128 119.25 0 0 176 174 172 174 548 Jk(a-b+) x Jk(a-b+) 26 28.45 0 0 0 0 68 68 68

500 500.00 1,385 - - -

X2 = 3.16

Announcements

Washington State Association of Blood Banks The Washington State Association of Blood

Banks held its meeting on May 22, 1965 at King County Blood Bank.

The following officers were elected: President, A. Lempert, M.D.-Mt. Vernon Vice-president, Me1 Mangum-Yakima Secretary-Treasurer, Patricia Young-Tacoma It was voted to change the association’s name

to Northwest Association of Blood Banks and in order to interest neighboring states and provinces in the Association.

Illinois House Votes to License Blood Banks Legislation to require licensing of clinical

blood banks as a public health measure was passed by the Illinois House on June 7, 1965.

The principal sponsor, Rep. John Merlo (D., Chicago), said the bills were needed to stem the increasing rate of persons infected with diseases from transfusions with blood that has been improperly handled. The measures were sent to the Senate without a dissenting vote.

The legislation would authorize the state health department to administer the licensing and to establish standards for the clinics.

Merlo’s bills were prepared after a two-year study by a legislative commission of the regu- lation and operation of blood banks of other states, including New York and California.

The law creating the commission was spon- sored by Merlo in the 1969 legislative session.

Faith Prevents a Transfusion; Wife, Child Die -From the Chicago Tribune, June 8, I965 ADELAIDE, Australia, June 7 (Reuters)-A man

said tonight he had “no regrets whatever” about refusing to authorize a blood transfusion for his wife, who died earlier today giving birth to twins.

Both Mr. and Mrs. Walter Stephens were members of the Jehovah’s Witnesses sect, which forbids blood transfusions on religious grounds. Only one of the twins survived. The second twin was stillborn when Mrs. Stephens, 24. suffered a rupture and severe hemorrhaging.

Her 27-year-old husband, who was at the hospital in the south Australian town of Why- alla while his wife was dying, refused to author- ize blood transfusions. Mn. Stephens had re- fused to accept the transfusions.