V e r s a t i l i t y

s t r e n g t h

F l e x i b i l i t y

The Choice of surgeons for half a century

SURGICEL® Absorbable Hemostats have been trusted for half a century to stop surgical bleeding.1,2

PRovEn SAfEty

• Proprietary oxidized regenerated cellulose (OrC) technology1 designed to ensure purity and consistency

• Plant-based product with minimal tissue reaction3

• Fully absorbable within 7-14 days3

PRovEn EffICACy

• Fast hemostasis1

• Used in more hospitals than any other absorbable hemostat product1

CHoICE & ConvEnIEnCE

• available in 3 unique forms—ideal for a broad range of specialties and procedures3

• long shelf life—at room temperature*3

• ready to use out of the package

• Flexible and malleable, can be cut to size

*SURGICEL® Original Absorbable Hemostat and SURGICEL® NU-KNIT® Absorbable Hemostat have a 5-year shelf life; SURGICEL® FIBRILLARTM Absorbable Hemostat has a 3-year shelf life.

S t o p b l e e d i n g f a S t w i t h t h r e e

p r o v e n p e r f o r m e r S

p r o v e n b a c t e r i c i d a l p r o p e r t i e S

sUrgiCel® absorbable hemostat is the first and only absorbable hemostat that is proven bactericidal against a broad range of gram-positive and gram-negative organisms including various antibiotic-resistant bacteria (Mrsa, Vre, PrsP and Mrse)†,4,5

The experimental model: 140 guinea pigs were utilized to simulate the development of intra-abdominal abscess and/or peritonitis, which can occur in humans when a large blood clot becomes contaminated.

Clinical significance of these animal or in vitro data has yet to be determined.

Closing SURGICEL® Absorbable Hemostat into a contaminated wound without drainage may lead to complications and should be avoided.

†Methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), penicillin-resistant Streptococcus pneumoniae (PRSP), methicillin-resistant Staphylococcus epidermidis (MRSE).

‡CFU=Colony Forming Units

in vivo animal studies have proven sUrgiCel® absorbable hemostat, in contrast to other hemostatic agents studied, does not enhance infection6-9

ControlAbsorbable Gelatin Sponge Collagen Hemostatic AgentSURGICEL® Absorbable Hemostat

Sur

vivi

ng P

opul

atio

ns

Days

50

40

30

20

10

00 5 10 20 30

ControlSURGICEL® Original Absorbable HemostatSURGICEL® NU-KNIT® Absorbable HemostatSURGICEL® FIBRILLARTM Absorbable Hemostat

CFU

/mL‡

Time (hours)

1.00E+10

1.00E+9

1.00E+8

1.00E+7

1.00E+6

1.00E+5

1.00E+4

1.00E+3

1.00E+2

1.00E+1

00 6 12 18 24

Logarithmic Reduction of MRSA4

vERSAtILIty

• thin layers enhance your ability to visualize and work on bleeding site

• Fibril material provides broad surface area coverage

oPtImAL AdHEREnCE

• soft, layered material conforms and “melts in” to bleeding tissue—until you remove it1

• larger surface area advances hemostasis action

IdEAL ConfoRmAbILIty

• lightweight layers and tufts—peel off as much or as little as desired10

• Use it in any size, shape, or thickness—as needed for your specific application10

• Well suited for use in craniotomy, laminectomy3 and coronary artery bypass graft procedures to control bleeding on the anastomosis site

SURGICEL®

FIBRILLAR™

Absorbable Hemostat

StRonGER mAtERIAL

• Dense knit material provides high tensile strength in the presence of heavy bleeding1

• thick weave designed to stay together during surgery; permits suturing

GREAtER CovERAGE AREA

• large surface area provides maximal coverage

• soft, pliable weave designed to hold a suture3 and for placement on delicate tissue11

vERSAtILE

• Wrap it, suture it in place, even insert it through a trocar, for unsurpassed application control

• ideal for use in trauma, laparoscopic surgery, and various procedures, including sternotomies and solid organ11

SURGICEL®

NU-KNIT®

Absorbable Hemostat

ExCELLEnt HEmoStASIS WItH oPtImAL HAndLInG

• Proven record of safety and efficacy for a broad range of bleeding situations1,3

• sheer weave allows visibility of the bleeding site

• Flexible texture conforms to irregular surfaces—provides optimal conformability in a fabric1

SURGICAL ConfoRmAbILIty

• Compatible with electrocautery3

• easily removed after hemostasis is achieved3

• easily cut or folded for use in endoscopic procedures1

SURGICEL® ORIGINAL Absorbable Hemostat

the SURGICEL® Hemostat that’s right for your procedure.

three proven & trusted performers— sUrgiCel® absorbable hemostats provide a

unique combination of hemostatic effectiveness, absorbability, and bactericidal properties.4,5

for use in a broad range of procedures3

• neurosurgery

• Ortho-spine

• Cardiovascular

• Peripheral Vascular

• general surgery

the Choice of surgeons for half a century

• trauma

• Minimally invasivesurgery

• Urology

• ent Procedures

c h o o S e …

Trusted by surgeons for half a century to stop bleeding fast.• Proprietary OrC technology1

• safe—plant-based product3

• bactericidal advantage4-9

References: 1. Data on file, Ethicon, Inc. 2. Hong Y, Loughlin K. The use of hemostatic agents and sealants in urology. J Urol. 2006;176:2367-2374. 3. SURGICEL® Absorbable Hemostat. Full Prescribing Information, Ethicon, Inc. 4. Spangler D. Rothenburger S, Nguyen K, Jampani H, Weiss S, Bhende S. In vitro antimicrobial activity of oxidized regenerated cellulose against antibiotic-resistant microorganisms. Surg Infect. 2003;4(3):255-262. 5. Data on file, in vivo study. Ethicion, Inc. 6. Dineen P. Antibacterial activity of oxidized regenerated cellulose. Surg Gynecol Obstet.1976;142:481-486. 7. Dineen P. The effect of oxidized regenerated cellulose on experimental intravascular infection. Surg. 1977;82:576-579. 8. Dineen P. The effect of oxidized regenerated cellulose on experimental infected splenotomies. J Surg Res. 1977;23:114-116. 9. Kuchta N, Dineen P. Effects of absorbable hemostats on intra abdominal sepsis. Infect in Surg. 1983;2:441-444. 10. Amar A, Levy M. Applications of topical hemostatic agents in neurosurgery. Contemp Surg. 1996;4(6):1-3. 11. Mair H, Kaczemared I, Oberhoffer M, Groetzner J, Daebritz S, Reicharet B. Surgicel NuKnit hemostat for bleeding control of fragile sternum. J Thorac Cardiovasc Surg. 2005;130(2):605-606.

to order: 1-800-255-2500For technical support: 1-877-384-4266www.surgicel.comethicon, inc. Please see Essential Prescribing Information in pocket.

©2009 ethicon, inc. DhMxxxx

Size/Code Packaging

SURGICEL® FIBRILLARTM Absorbable Hemostat

1 in x 2 in / 1961 10 eaches per box/case

2 in x 4 in / 1962 10 eaches per box/case

4 in x 4 in / 1963 10 eaches per box/case

SURGICEL® NU-KNIT® Absorbable Hemostat

1 in x 1 in / 1940 24 eaches per box/case

1 in x 3.5 in / 1941 10 eaches per box/case

3 in x 4 in / 1943 24 eaches per box/case

6 in x 9 in / 1946 10 eaches per box/case

SURGICEL® Original Absorbable Hemostat

2 in x 14 in / 1951 24 eaches per box/case

4 in x 8 in / 1952 24 eaches per box/case

2 in x 3 in / 1953 24 eaches per box/case

0.5 in x 2 in / 1955 24 eaches per box/case