the brain stem ii
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PONS & MID-BRAIN
STRUCTURE/BLOOD SUPPLY/CRANIAL NERVES ATTACHMENTS
Lecture….by Prof. AnsariSunday, April 9, 2023
(for BDS SEMESTER II students only)
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OBJECTIVES
• Structure of pons and midbrain.• Cranial nerves attachment.• Other nuclei present at these levels.• Blood supply• Cross section- grey matter and white matter.
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PONS• It is a part of brain stem.• It lies between midbrain and medulla oblongata.• It has a basilar part/ ventral part, and a dorsal part which
forms the floor of IV ventricle.• Three cranial nerves are related to pons, trigeminal nerve
is attached to the pons on ventral part.• Abducent nerve is related at the lower border of pons and
pyramid.• Occulomotor nerve arises at the upper border of pons, in
the interpeduncular fossa.
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CRANIALNERVESATTACHED AT THE BASEOF BRAIN
CRANIALNERVESATTACHED AT THE BASEOF BRAIN
6CROSS SECTION OF PONS
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BASILAR PART
TEGMENTUM PART
IVVENTRICLE
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Nuclei of cranial nerves in pons
• Facial nerve nuclei, motor / sensory/autonomic.
• Trigeminal nuclei, motor/ main sensory/spinal/ mesencephalic.
• Abducent nucleus / purely motor.• Nuclei pontis.
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Floor of IV ventricle
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White fibers at pons
• Corticopontine fibers
• Corticospinal fibers
• Corticopontocerebellar fibers
• Corticonuclear fibers
• Trapezoid body12
13OVERVIEW OF PONS
Mesencephalon
• It is at the cranial end of pons.
• It has a dorsal portion called as tectum.
• The ventral portion is called as cerebral peduncle.
• The space between the two cerebral peduncle is the interpeduncular fossa.
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Structures in the interpeduncular fossa
• 1.Optic nerve• 2.Optic chiasma• 3.Optic tract• 4.Tuber cinereum• 5.Mammillary bodies• 6.Ant.perforated
substance.• 7.Olfactory tract• 8.Pons• 9=Uncus
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Cross section of midbrain
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Inferior colliculus
SuperiorCerebellarPeduncle decussation
Substantia nigraSubstantia nigra
Cerebral peduncleCerebral peduncle
PAG
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Superior colliculus
Oculomotor fibers
Various nucleiat midbrain
• Oculomotor nucleus• Trochlear nucleus• Mesencephalic nucleus• Red nucleus• Substantia nigra• Edinger-Westphal nucleus
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White matter at mesencephalon
• Superior cerebellar peduncles decussations• Medial lemniscus/lateral lemniscus/trigeminal
lemniscus/spinal lemniscus• Crus cerebri
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Blood supply of pons &midbrain
• Cortical branches and central branches arise from basilar artery and circle of Willis.
• Pontine hemorrhage leads to bursting head ache, pinpoint pupil, and hyperthermia.
• Injury to the Corticospinal fibers leads to hemiplegia.
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21CIRCLE OF WILLIS
Red nucleus and substantia nigra• They are concerned with the extrapyramidal tract.
• Injury to these nuclei will result in tremors, Parkinsonism, and nystagmus.
• These symptoms can be corrected by supplementing the neurotransmitter dopamine.
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Periaqueductal gray
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Electrical stimulation of the PAG results in immediate and profound analgesia
• Stimulation of the dorsal and lateral aspects of the PAG (in the rat) can provoke defensive responses characterized by freezing immobility, running, jumping, tachycardia, and increase in blood pressure.
• Stimulation of the caudal ventrolateral PAG can result in an immobile, relaxed posture known as quiescence.
• It also plays a role in female copulatory behavior.
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Periaqueductal gray
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RED NUCLEUSCEREBRAL AQUEDUCT
References
• http://legacy.owensboro.kctcs.edu/gcaplan/anat/notes/api%20notes%20l%20central%20nervous%20system-brain.htm
• http://www.dartmouth.edu/~rswenson/NeuroSci/figures/Figure_15.htm
• http://instruct.uwo.ca/anatomy/530/530notes.htm#TOPICS
• http://www.mcqsonline.net/2009/05/brainstem-anatomy-mnemonics.html
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A 62-year old male has sustained several injuries from a car accident. Upon administering a neurological examination, you suspect that the
patient has damage to the right caudal medulla. Why do you think this?
A. The patient's right eye exhibits hypertropia and he complains of diplopia,B. The patient's tongue deviates towards to right when you asked him to stick it out
and his uvula deviates towards the left when you ask him to say, "aahhh". C. The patient has a loss of taste on the right anterior 2/3rds of his tongue D. The patient exhibits anosmia (inability to smell) E. The patient complains of excruciating pain on the right side of his face
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