The AP Bio Midterm ExamTuesday 1/22/13 8AM

24 True/False (36 pts. Total) 72 Multiple Choice (144 pts. Total) 2 Genetics Problems (40 pts. Total) 4 Short Answer Questions (30 pts. Total) 1 Full Essay (50 pts. Total) … and Extra Credit! Calculators Permitted / Formula Sheet

Provided

AP Midterm Exam Format

Some questions will be fact-based

Which of the following occurs during meiosis but not during mitosis? A) separation of sister chromatids B) cell division C) crossing over of homologous chromosomes D) breakdown of the nuclear envelope E) lineup of chromosomes in the center of the cell

Multiple Choice

Some questions will be fact-based

Which of the following occurs during meiosis but not during mitosis? A) separation of sister chromatids B) cell division C) crossing over of homologous chromosomes D) breakdown of the nuclear envelope E) lineup of chromosomes in the center of the cell

Multiple Choice

Some questions will ask you to apply your knowledge 70% of earth’s population is lactose intolerant. The

gene for lactose metabolism in intestinal cells is not expressed after the age of three. The majority of Europeans and US residents with European ancestry are lactose tolerant. Their intestinal cells continue to produce lactase throughout life. This mutation has been traced to a single G to C mutation approximately 14,000 base pairs upstream of the lactase gene.

Multiple Choice

Some questions will ask you to apply your knowledge The model that best represents the likely effect

of the mutation is that the G to C change has:

Multiple Choice

Some questions will ask you to apply your knowledge The model that best represents the likely effect

of the mutation is that the G to C change has:

Multiple Choice

Multiple Choice

Multiple Choice

Multiple Choice

Hemophilia is a recessive sex-linked disorder that prevents blood from clotting properly. If a man with hemophilia has a child with a woman that does not have hemophilia, what are the overall odds that they will have a child with hemophilia? (You don’t have any further information on the woman’s background)

Genetics Problems

Hemophilia is a recessive sex-linked disorder that prevents blood from clotting properly. If a man with hemophilia has a child with a woman that does not have hemophilia, what are the overall odds that they will have a child with hemophilia? (You don’t have any further information on the woman’s background)

Overall 2 in 8 (25%)

Genetics Problems

Genetics Problems

An electrophoresis gel from the Sanger method produces the following results. Based on it, give the DNA sequence for the original strand of DNA.

Short Answer

ddATP ddCTP ddTTP ddGTP

CGCAGCGATACT --- > GCGTCGCTATGA

ddATP ddCTP ddTTP ddGTP

Full Essay