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#$ Definition of %nsulin&$ !oles of %nsulin

'$ (he accidental discovery of %nsulin)$ Diseases*$ Synthetic insulin+$ (he obel -ri.e/$ Bibliogra"hy

Contens

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1. Definition of %nsulin

• Insulin is a hormone produced in thepancreas which regulates the amountof glucose in the blood.

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2.Roles of Insulin

Insulin regulateshow the body usesand stores glucose

and fat

Insulin helps cellsto take in glucose

to be used forenergy.

If the body hassu cient energy,insulin signals the

liver to take upglucose and store

it as glycogen

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3.The accidental discovery of Insulin

• In 1921 two researchers, Fredanting and !harles est were

looking for a cure for diabetes"• #hey start to perform their

e$periments using animals

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%.#he accidental discovery of Insulin

• #o test theirtheory antingand est used

1& dogs.

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%.#he accidental discovery of Insulin

• #hey made thedogs diabetic andthen investigatedtreatments for thediabetes.

• #he result of their

research hassaved the lives ofmillions of people.

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The islets ofLangerhans are theregions ofthe "ancreas thatcontain its endocrine

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)$Diseases• (y"e # diabetes : t he body1s o2n

immune cells attac3 the insulin

"roducing beta cells of the "ancreas$• (his leads to an absolute insulindeficiency

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)$Diseases

(y"e &:•

body fails to• "roduce the re4uiredamount of insulin

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)$Diseases

%nsulinoma:the "ancreas is"roducing too

much insulin

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'.(ynthetic Insulin• (ynthetic insulin is made in

laboratories and is used by thosewitch body can)t produce insulin"

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+$(he obel -ri.e

• #he news of thesuccessful treatmentof diabetes withinsulin rapidly spread"

• In 192% the *obel!ommittee decided to

award anting andest the *obel +ri e

in +hysiology or

-edicine.

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/$ Bibliogra"hy

• http //www.nobelpri e.org/educational/medicine/insulin/discovery0insulin.html

• http //themedicalbiochemistrypage.org/insulin.php

http://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://themedicalbiochemistrypage.org/insulin.phphttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.htmlhttp://www.nobelprize.org/educational/medicine/insulin/discovery-insulin.html

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Thank you for yourattention