the 46th annual meeting of the japanese society for...

The 46th Annual Meeting of The Japanese Society for Immunology Program for Workshop

Session Title Date Venue Chair1 Chair2 Submission ID Program No. 1st Author Affiliation Title Presentation Discussion

100298 1-A-W1-1-O/P Sho SHIBATADepartment of Immune Regulation, Tokyo Medical and Dental

University, Tokyo, Japan

Monocyte-derived macrophages in the lung contribute to the development of pulmonary emphysema

through MMP-12 production in a mouse model of COPD 7 3

100041 1-A-W1-3-O/P Satoko Tahara-HanaokaDepartment of Immunology, Faculty of Medicine, University of

Tsukuba, Tsukuba, JapanInhibition of house dust mite-induced Th2 responses by Allergin-1 immunoreceptor on dendritic cells 7 3

100100 1-A-W1-4-O/P Koji HayashizakiDepartment of Immunology, Graduate School of Medicine, Chiba

University, Chiba, JapanMyosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation 7 3

100189 1-A-W1-9-O/P Aiko SakuDepartment of Allergy and Clinical Immunology, Graduate School of

Medicine, Chiba University, Chiba, Japan

Lung epithelial fucosylation promotes the development of house dust mite (HDM)-induced allergic

airway inflammation. 7 3

100268 1-A-W1-10-O/P Tomomitsu MiyasakaDivision of Pathophysiology, Department of Pharmaceutical Sciences,

Faculty of Pharmaceutical Sciences, Tohoku Medical and

Pharmaceutical University, Sendai, Japan

Possible involvement of CD103+ dendritic cells in female-predominant Th2 priming in

asthma 7 3

100356 1-A-W1-11-O/P Kentaro Fujiwara Dept. of ImmunologyM1 macrophages mediate attenuation of bronchial asthma by matrix-metalloproteinase-

2 7 3

100199 1-A-W1-14-O/P Katsuhide OkunishiInstitute for Molecular and Cellular Regulation, Gunma University,

Maebashi, JapanRab27 effector exophilin5 regulates IL-33 signaling in allergic immune responses 7 3

100291 1-A-W1-17-O/P Kazuyuki NakagomeDepartment of Respiratory Medicine and Allergy Center, Saitama

Medical University, Saitama, JapanElevated periostin concentrations in the bronchoalveolar lavage fluid of eosinophilic pneumonia 7 3

100300 1-A-W2-7-O/P Masaya MatsudaLaboratory of Immunopharmacology, Faculty of Pharmaceutical

Sciences, Setsunan University, Osaka, JapanEffects of subcutaneous immunotherapy (SCIT) on regulatory T cells in pollinosis patients 7 3

100484 1-A-W2-8-O/P Kazuya TakedaLaboratory of Immune regulation, Immunology Frontier Research

center, Osaka University, Suita, Japan

Ectopic T-B interaction for antigen-specific IgE antibody responses in nasal polyps of Eosinophilic

chronic rhinosinusitis patients 7 3

100110 1-A-W2-9-O/P Dat Nguyen-TienDivision of Molecular Biology, Research Institute for Biomedical

Sciences, Tokyo University of Science

A selection technique for human IgE+ memory B cells and the function of the

“new” isoform of human IgE 7 3

100113 1-A-W2-10-O/P Mariana AlmeidaDepartment of Immunology, Faculty of Medicine, University of

Tsukuba, Tsukuba, Japan

Inhibition of house dust mite-induced MAP kinase activation in dendritic cells by Allergin-1

immunoreceptor 7 3

100205 1-A-W2-12-O/P Shihono KatoLaboratory for Innate Immune Systems, RIKEN, IMS, Kanagawa,

Japan

Role of ILC2 in the formation of maternal allergic inflammation and allergic susceptibility of the

offspring 7 3

100232 1-A-W2-13-O/P Mio OhashiDepartment of Immunoregulation, Institute of Medical Science, Tokyo

Medical University, Tokyo, Japan

Prediction of Chemical Respiratory and Contact Sensitizers by OX40L Expressionin Dendritic Cells

Using a Novel 3D Co-Culture System 7 3

100311 1-A-W2-14-O/P Kano TanabeDepartment of Medical Technology, Kumamoto Health Science

University, Kumamoto, JapanCaMKII regulates IgE class switch recombination via TRAF3 ubiquitination 7 3

100519 1-A-W2-16-O/P Ayako TakamoriAtopy (Allergy) Research Center, Juntendo University School of

Medicine, Tokyo, Japan

Ceramide-CD300f interaction inhibits Mrgprb2-mediated mast cell activation and pseudo-

allergic drug reactions in mice 7 3

100614 1-B-W3-1-O/P Ryota SatoDivision of Innate Immunity, The Institute of Medical Science, The

University of Tokyo, Japan

Requirement of glycosylation machinery in Toll-like receptor responses revealed by

CRISPR/Cas9 screening 7 2

100070 1-B-W3-2-O/P Sachiko　 Akashi-Takamura Aichi Medical University School of Medicine, Nagakute, Japan C4b binding protein negatively regulates cell-surface TLRs response 7 2

100216 1-B-W3-3-O/P Ken TakashimaDepartment of Immunology, Graduate School of Medicine, Hokkaido

University, Sapporo, JapanNovel Negative Regulators for MDA5-Mediated Innate Immune Response 7 2

100641 1-B-W3-4-O/P Michihiro TakahamaInstitute of Advanced Medical Sciences, Tokushima University,

Tokushima, JapanRAB2B-GARIL5 complex promotes innate immune response against DNA virus 7 2

100188 1-B-W3-5-O/P Naoya SakaguchiResearch Institute for Microbial Diseases (RIMD), Osaka University,

Osaka, Japan

Role of GABARAP subfamily in the regulation of non-canonical inflammasome

activation 7 2

100322 1-B-W3-6-O/P Kohsuke Tsuchiya Cancer Research Institute, Kanazawa University, Kanazawa, Japan Caspase-1 serves as an apoptosis-initiating caspase in the absence of Gasdermin D (GSDMD) 7 2

100181 1-B-W3-7-O/P Ho Minh VanDepartment of Emergency and Critical Care Medicine, Graduate

School of Biomedical and Health Sciences, Hiroshima University

Detection of ATP-dependent inflammatory suppression of the innate immune response in

septic patients 7 2

100078 1-B-W3-8-O/P Masahiro NagataDepartment of Molecular Immunology, Research Institute for

Microbial Diseases, Osaka University, Osaka, JapanIntracellular metabolite, β-glucosylceramide, is an endogenous adjuvant acting through Mincle 7 2

Time

Tatsuya

Saitoh

Takuya

UehataW3

Endogenous

innate immunity

and

inflammation-1

Dec. 12

(Tue.), 201713:20 14:40 Room B

Tomohiro

YoshimotoRyoji YagiW2

Allergy-2:

Upper airway

allergic

inflammation

and allergic

responses

Dec. 12

(Tue.), 201714:55 16:15 Room A

Kenji IzuharaKoubun

YasudaW1

Allergy-1 :

Lower airway

allergic

inflammation

Dec. 12

(Tue.), 201713:20 14:40 Room A

1 / 12

Session Title Date Venue Chair1 Chair2 Submission ID Program No. 1st Author Affiliation Title Presentation DiscussionTime

100040 1-B-W4-1-O/P Ayako WakabayashiDepartment of Microbiology and Immunology, Nippon Medical School,

Tokyo, Japan

Enhancement of epithelial cell death, cytoplasmic HMGB1 expression in IECs, and increase of

HMGB1 release by oral CT-stimulation 7 2

100529 1-B-W4-2-O/P Eri KumakiDepartment of Pediatrics and Developmental biology, Tokyo Medical

and Dental University Graduate School of Medical and Dental

Sciences, Tokyo, Japan

Abberant Neutrophil Function in PSTPIP1 mutations 7 2

100325 1-B-W4-3-O/P Akiko Ishitani Nara Medical University, Kashihara, Nara, Japan

The three faces of F: HLA-F as a ligand for KIRs, a cofactor in antigen presentation, and a

receptor on B cells and monocytes, combined in an immunoregulatory capacity centered on the

inflammatory response.7 2

100353 1-B-W4-4-O/P Toshiaki Totoki Dept. of ImmunologyOverexpression of protein S exacerbates carbon tetrachloride-induced liver injury and

fibrosis 7 2

100493 1-B-W4-5-O/P Maehara AkieAtopy (Allergy) Research Center, Juntendo University Graduate

School of Medicine, Tokyo, Japan

Identification and characterization of a novel mutation of NLRP1 in a patient with a rare disease

involving severe liver fibrosis 7 2

100619 1-B-W4-6-O/P Kiyoharu FukushimaDepartment of Host Defense, Research Institute for Microbial

Diseases (RIMD), Osaka University, Osaka, Japan.Screening of causative genes for fibrosis development in mice. 7 2

100474 1-B-W4-7-O/P Yukari SaitoDepartment of Immune Regulation, Research Center for Hepatitis

and Immunology, Research Institute, National Center for Global

Health and Medicine, Chiba, Japan

Activation of NK/group1-innate lymphoid cells in adipose tissues depends on the composition of fatty

acids in high fat diet. 7 2

100270 1-B-W4-8-O/P Kafi N. EaleyLaboratory for Innate Immune Systems, RIKEN IMS, Yokohama,

Japan

Mechanisms for the regulation of adipose tissue expansion and remodeling by group 2 innate lymphoid

cells 7 2

100002 1-B-W4-9-O/P Toshihiko KobayashiDepartment of Molecular Immunology & Inflammation, Research

Institute, NCGMRegulatory role of an oligopeptide transporter SLC15A3 during the systemic inflammation 7 2

100588 1-C-W5-1-O/P Ben RaveneyDepartment of Immunology, National Institute of Neuroscience,

NCNP, Kodaira, Tokyo, Japan

Eomes-positive cytotoxic T helper cells: a new pathogenic immune cell subset in secondary

progressive multiple sclerosis? 7 3

100535 1-C-W5-2-O/P Chenyang ZHANGDepartment of Immunology, National Institute of Neuroscience,

National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.

Antigen-presenting cells promote Eomes expression in helper T cells through ectopic

expression of prolactin under chronic neuroinflammation 7 3

100405 1-C-W5-3-O/P Youwei LinDepartment of Immunology, National Institute of Neuroscience,

National Center of Neurology and Psychiatry

Inverse vaccination by superior dominant peptide inhibit the reactivity to disease-associated antigens

and promote tissue-repair capacity in stabilized antigen-specific regulatory T cells to control of

relapsing and progression of animal model of multiple7 3

100158 1-C-W5-4-O/P Fumitaka Sato Kindai University, Osakasayama, JapanProtective and detrimental effects of curdlan, a Th17 cell inducer, in immune-mediated demyelination

induced by a neurotropic viral infection 7 3

100342 1-C-W5-5-O/P Fumihiro YanagimuraDepartment of Neurology, Brain Research Institute, Niigata

University, Niigata, Japan

Differential dynamics of mucosal-associated invariant T cells in the blood and the CNS lesions of

patients with neuromyelitis optica 7 3

100506 1-C-W5-6-O/P Daisuke KamimuraPsychoimmunology, Institute for Genetic Medicine, Graduate School

of Medicine, Hokkaido University, Sapporo, Japan

Light-Gateway Reflex; Photopic light suppresses retinal inflammation via down-regulation of a

regional adrenergic pathway 7 3

100129 1-C-W5-7-O/P Satoshi YamadaDepartment of Intelligent Mechanical Engineering, Okayama

University of Science, Okayama, JapanComputer model of a gateway of immune cells across blood-brain barrier 7 3

100528 1-C-W5-8-O/P Yasunobu ArimaDivision of Psychoimmunology, Institute for Genetic Medicine and

Graduate School of Medicine, Hokkaido University, Sapporo, Japan

Stress-Gateway Reflex, which establishes brain micro-inflammation at specific vessels, creates a new

neural pathway, which induces the dysregulation of organ homeostasis 7 3

100138 1-C-W6-1-O/P Ota MitsutoshiDivision of Psychoimmunology, Institute for Genetic Medicine,

Hokkaido University, Sapporo, Japan

NF-kB Arthritis Inducer 1 (NAI1) in chondrocytes regulates joint inflammation via NF-kB

activation 7 3

100618 1-C-W6-2-O/P Ikuma NakagawaDivision of Psychoimmunology, Institute for Genetic Medicine,

Hokkaido University, Hokkaido, Japan

Primary Sjögren’s syndrome-associated gene STF1 regulates

inflammation via NF-kB pathway 7 3

100037 1-C-W6-4-O/P Kojiro SatoDepartment of Rheumatology and Applied Immunology, Saitama

Medical University, Saitama, Japan

Analysis of the function of Nfatc1 isoforms in the differentiation of osteoclasts and an attempt to make

short-form specific Nfatc1 knockout mice with the CRISPR/Cas9 system 7 3

100630 1-C-W6-5-O/P Michio Yasunami Saga-Ken Medical Centre Koseikan, Saga, Japan

Principal contribution of HLA-DQ alleles, DQB1*06:04 and

DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese

population7 3

100172 1-C-W6-6-O/P Tomomi SatoDepartment of Fundamental Biosciences, Shiga University of Medical

Science, Shiga, Japan

Characterization of rheumatoid arthritis-associated interstitial pneumonia using collagen-induced

arthritis mice 7 3

100384 1-C-W6-7-O/P Kunihiro OtsukaDepartment of Oral Molecular Pathology, Institute of Biomedical

Science, Tokushima University Graduate School, Tokushima, JapanAnalysis of follicular helper T cells in a mouse model for Sjögren’s syndrome 7 3

100545 1-C-W6-9-O/P Namiko OkabeDepartment of Rheumatology and Clinical Immunology, Graduate

School of Medicine, Kyoto University, Kyoto, JapanMyelin basic protein promotes experimental arthritis via non-T cells. 7 3

100576 1-C-W6-11-O/P Soo-hyun ChungCenter for Animal Disease Models, Research Institute for Biomedical

Sciences, Tokyo University of Science, Noda, JapanTruncated glycan and C-type lectin ; a new therapeutic target for autoimmune arthriti 7 3

Naozumi

IshimaruHiroto TsuboiW6

Tissue-specific

immune

diseases II

Dec. 12

(Tue.), 201714:55 16:15 Room C

Mitsuru

Matsumoto

Daisuke

KamimuraW5

Tissue-specific

immune

diseases I

Dec. 12

(Tue.), 201713:20 14:40 Room C

Osamu

Takeuchi

Sachiko

Takamura

(Akashi)

W4

Endogenous

innate immunity

and

inflammation-2

Dec. 12

(Tue.), 201714:55 16:15 Room B

2 / 12

100479 1-D-W7-1-O/P Satoshi FukuyamaDivision of Virology, Department of Microbiology and Immunology,

Institute of Medical Science, University of Tokyo, Tokyo, JapanEffect of aging on the host response to avian influenza A(H7N9) virus infection in non-human primates 6 2

100431 1-D-W7-2-O/P Hiroshi UekiDivision of Virology, Department of Microbiology and Immunology,

Institute of Medical Science, University of TokyoVisualization of immune responses to influenza virus in mouse lung by using two-photon microscopy 6 2

100242 1-D-W7-3-O/P Natsuko Imakita Department of Immunology, Nara Medical University, Nara, JapanThe contribution of histone methyltransferase Setdb2 in the pathogenesis of influenza associated

encephalopathy 6 2

100116 1-D-W7-4-O/P Kayoko SatoInfluenza Virus Research Center, National Institute of Infectious

Diseases, Tokyo, Japan

TLR agonists enhance avidity and ADCC activities of virus-specific antibodies upon a booster

immunization of influenza vaccines 6 2

100102 1-D-W7-5-O/P Tatsuya YamazakiDepartment of Microbiology and Immunology, Aichi Medical

University, School of Medicine

Neutralizing anti-hemagglutinin IgG and IgA mAb induced by gene-base hydrodynamic

injection have a therapeutic effect in upper respiratory influenza virus infection 6 2

100246 1-D-W7-6-O/P Masaaki OkamotoDepartment of Immunology, Graduate School of Medical Sciences,

Kumamoto University, Kumamoto, Japan

Circulating miR-451a in extracellular vesicles regulate innate immune cells response to

influenza A virus vaccine 6 2

100587 1-D-W7-7-O/P Takeharu MinamitaniLaboratory of Infectious Diseases and Immunity, National Institutes of

Biomedical Innovation, Health, and Nutrition, Ibaraki, Osaka, Japan

T cell and NK cell-mediated immune surveillance interferes with Epstein-Barr virus LMP-induced

lymphomagenesis in germinal center B cells 6 2

100266 1-D-W7-8-O/P Haruna OkudeLaboratory of Molecular Immunobiology, Nara Institute of Science and

Technology, Nara, JapanInduction of cell death by imiquimod (R837) and its role in immune responses 6 2

100066 1-D-W7-9-O/P Tomoko TakahashiDepartment of Biological Sciences, Graduate School of Science, The

University of Tokyo

LGP2 upregulates apoptosis-related genes by acting as an RNA silencing modulator during viral

infection 6 2

100226 1-D-W7-10-O/P Akihiko KomuroNiigata University of Pharmacy and Applied Life Sciences, Niigata,

Japan

A possible role of TAR-RNA binding protein phosphorylation in MDA5/LGP2-mediated cellular

responses by Cardiovirus infection 6 2

100053 1-D-W8-1-O/P Takayuki Chikata Center for AIDS Research, Kumamoto University, Kumamoto, Japan Control of HIV-1 by an HLA-B*52:01-HLA-C*12:02 protective haplotype 6 2.5

100313 1-D-W8-2-O/P Hayato Murakoshi Center for AIDS Research, Kumamoto University, Kumamoto, JapanImpact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on

HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation 6 2.5

100346 1-D-W8-3-O/P Chengcheng Zou Center for AIDS research, Kumamoto University, Kumamoto, Japan Conserved epitope-specific CTLs controlling HIV-1 replication 6 2.5

100177 1-D-W8-4-O/P Takamasa Ueno Center for AIDS Research, Kumamoto University, Kumamoto, JapanRelative resistance of MHC-B to Nef-mediated downregulation is conserved among primate

lentiviruses and correlates with reduced viral loads in HIV-1-infected individuals 6 2.5

100024 1-D-W8-5-O/P Eiji SHINYA Nippon Medical School, Tokyo, Japan

Hematopoietic cell kinase (Hck) augmented the interaction between HIV-1 Nef and SERINC5, which

might promote HIV-1 infection by excluding SERINC5 from virion incorporation in immature dendritic

cells6 2.5

100210 1-D-W8-6-O/P Nami Iwamoto Immuno Technology Section, Vaccine Research Center, NIAID, NIHDevelopment of Chimeric Antigen Receptor (CAR)-Transduced CD8 T cells Using SIV-specific

Neutralizing Anibodies 6 2.5

100600 1-D-W8-7-O/P Daichi YamasobaLaboratory of Infection and Prevention, Institute for Frontier Life and

Medical Sciences, Kyoto University, Kyoto, JapanIdentification of a novel HIV-1 restriction factor which selectively degrades viral transcripts. 6 2.5

100263 1-D-W8-8-O/P Takuya SueyoshiLaboratory of Molecular Immunobiology, Graduate School of

Biological Sciences, Nara Institute of Science and Technology

(NAIST), Nara, Japan

RNA-binding protein Hu antigen R (HuR) plays an important role in antiviral innate immune responses

via mRNA stabilization 6 2.5

100170 1-D-W8-9-O/P Takahisa KouwakiDepartment of Immunology, Graduate school of Medical Sciences,

Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan

Zyxin is a positive factor in a MAVS/IPS-1-dependent

type ? interferon expression

pathway during viral infection.6 2.5

100372 1-E-W9-1-O/P Takayuki MatsumuraDepartment of Immunology, National Institute of Infectious Diseases,

Tokyo, Japan

Balance of pro- and anti-inflammatory cytokines in immature myeloid cells involved in outcome

of severe invasive group A Streptococcus infections 7 3

100080 1-E-W9-2-O/P Imai TakashiDivision of Molecular Immunology, Medical Institute of Bioregulation,

Kyushu University, Fukuoka, Japan

Glycolipids in group A Streptococcus are recognized by Mincle to trigger host

immune responses 7 3

100383 1-E-W9-4-O/P Rin YokoyamaMedical Microbiology, Mycology and Immunology, Tohoku University

Graduate School of Medicine, Miyagi, Japan

Dectin-2-mediated signaling triggered by serotype 3 Streptococcus pneumoniae

and its contribution to host immune response 7 3

100491 1-E-W9-5-O/P Shogo Takatsuka Dept. Chemother. Mycoses, Nat. Inst. Infect. Dis.Follicular helper NKT cells augment germinal center B cell formation by a protein-based pneumococcal

vaccine 7 3

100490 1-E-W9-6-O/P Seitaro Nakagawa Department of Dermatology, Chiba UniversityStaphylococcus aureus virulent PSMα peptides induce keratinocyte IL-1 and IL-36

release to orchestrate IL-17-dependent skin inflammation 7 3

100340 1-E-W9-11-O/P Nobuhiro Nakamoto Keio University School of Medicine, Tokyo, JapanIntegrated collaboration of intestinal microbiota induces bacterial translocation and Th17

immune response in primary sclerosing cholangitis 7 3

100517 1-E-W9-15-O/P Ayako KaitaniAtopy (Allergy) Research Center, Juntendo University School of


CD300f suppresses neutrophil recruitment to LPS-injected skin: A role of CD300f in gram-negative

bacterial skin infections 7 3

Goro

MatsuzakiYuki KinjoW9

Immune

response to

bacteial

infections

Dec. 12

(Tue.), 201713:20 14:40 Room E

Takashi FujitaHiroyuki

OshiumiW8 Virus infection-2

Dec. 12

(Tue.), 201714:55 16:15 Room D

Taro KawaiMitsutoshi

YoneyamaW7 Virus infection-1

Dec. 12

(Tue.), 201713:20 14:40 Room D

3 / 12

100603 1-E-W10-1-O/P Ei'ichi IizasaDepartment of Immunology, Field of Infection and Immunity, Graduate

School of Medical and Dental Sciences, Kagoshima University,

Kagoshima

Two ITAM-coupled receptors recognizing Mycobacterial mycolic acid-containing lipids and having the

different roles. 7 3

100274 1-E-W10-3-O/P Naoto NouchiDivision of Host Defense, Medical Institute of Bioregulation, Kushu

University, Fukuoka, Japan

IL-21 signaling drives differentiation of short-lived effector CD8+T cells from early

effector cells but does not inhibit exhaustion following Mycobacterium bovis Bacillus

Calmette-Guérin infection in mice7 3

100160 1-E-W10-4-O/P Shihoko Komine-Aizawa Nihon University School of Medicine, Tokyo, JapanInduction of CD8+- MHC-I-restricted, antigen-specific T cells by recombinant BCG

protects against mycobacterial infection 7 3

100283 1-E-W10-5-O/P Yusuke TsujimuraTsukuba Primate Research Center, National Institutes of Biomedical

Innovation, Health and Nutrition, Ibaraki, JapanThe immune responses induced by BCG vaccination in the non-human primate TB model 7 3

100144 1-E-W10-7-O/P Yasunobu MiyakeDivision of Molecular and Cellular Immunoscience, Department of

Biomolecular Sciences, Faculty of Medicine, Saga University, Saga,

Japan

Immunosuppressive receptor, Siglec binds to pathogenic fungus, Trichophyton

mentagrophytes, and negatively regulates host immune responses 7 3

100304 1-E-W10-8-O/P Daiki TannoDepartment of Medical Microbiology, Mycology and Immunology,

Tohoku University Graduate School of Medicine

Dectin-2-mediated signaling triggered by the cell wall structures of Cryptococcus

neoformans 7 3

100458 1-E-W10-12-O/P Keigo UenoDepartment of Chemotherapy and Mycoses, National Institute of

Infectious Diseases, Tokyo, Japan

Dendritic cell-based vaccination induces lung resident memory Th17 cells that ameliorate pulmonary

infection with highly virulent Cryptococcus gattii 7 3

100044 1-F-W11-3-O/P Naoto NishiiDepartment of Molecular Immunology, Graduate School, Tokyo

Medical and Dental University

Systemic administration of low dose TLR7 agonist augments antitumor responses in the PD-1

checkpoint blockade-resistant and regulatory T cell-dominant murine tumor models 9 2

100565 1-F-W11-4-O/P Shime HiroakiDepartment of Immunology,?Nagoya City University Graduate School

of Medical Sciences, Nagoya, Japan

Toll-like receptor 2 ligand and interferon-γ suppress anti-tumor T cell responses by enhancing

the immunosuppressive activity of monocytic myeloid-derived suppressor cells 9 2

100375 1-F-W11-7-O/P Nobuo TsukamotoDivision of cellular Signaling, Institute for Advanced Medical

Research, Keio University School of Medicine, Tokyo, Japan

Berberine augments tumor antigen specific T cells in vivo through metabolic remodeling in

CD8+ T cells in tumors and lymph nodes 9 2

100371 1-F-W11-8-O/P Alok KumarDepartment of Immunology and Genomic Medicine, Graduate School

of Medicine, Kyoto University, Kyoto, Japan

Indicators of mitochondrial activation in T cells could be a biomarker to predict the PD-1

blockade therapeutic efficacy. 9 2

100617 1-F-W11-9-O/P kagawa MasakiDivision of Cellular Signaling Institute, for Advanced Medical

Research, Keio University School of Medicine

Immunomodulation of ovarian clear cell carcinoma by targeting HNF-1β-NF-kB-IL6 pathway

enhances anti-tumor immunity 9 2

100409 1-F-W11-11-O/P Chang-Yu ChenDepartment of Molecular Preventive Medicine, Graduate School of

Medicine, The University of Tokyo, Tokyo, Japan

Low-dose HMGN1 synergistically enhances anti-tumor immunity in CD4 depleting antibody-

treated mice 9 2

100393 1-F-W11-12-O/P Nanumi HanDivision of Immunobiology, Institute for Genetic Medicine, Hokkaido

University, Sapporo, Japan

Identification of factors that affect myeloid cells in immunotherapeutic-resistant

tumors 9 2

100365 1-F-W12-1-O/P Hirohito IshigakiDepartment of Pathology, Shiga University of Medical Science, Otsu,

Japan,

The hemoperfusion column removing LAP positive cells activates the tumor-specific immunity

in a cynomolgus monkey 10 3

100087 1-F-W12-2-O/P Harada Michishige RIKEN Center for Integrative Medical Science (IMS)CD81 is associated with non-apoptotic cell death in B cell lymphoma cell lines through HLA-

DRα/β engagement 10 3

100285 1-F-W12-4-O/P Takeshi Yamada System Biology,Kanazawa university,Kanazawa,JapanFeatures of immune response induced by Gemcitabine

in pancreatic ductal adenocarcinoma model 10 3

100192 1-F-W12-6-O/P Kikuya SugiuraDepartment of Advanced Pathobiology, Graduate School of Life and

Environmental Sciences, Osaka Prefecture University, Izumisano,

Japan

Manipulation of tumor microenvironment by cytokine gene transfection enhances dendritic cell-based

immunotherapy 10 3

100352 1-F-W12-10-O/P Yoshino TanakaDivision of Immunobiology, Institute for Genetic Medicine, Hokkaido

University, Sapporo, JapanDying but not dead cancer cells exert the effect of cell-based cancer vaccine 10 3

100224 1-F-W12-12-O/P Serina TokitaDepartment of Pathology, Sapporo Medical University School of

Medicine, Sapporo, JapanHLA-A24 ligandome analysis identifies a neoantigen that elicits strong CTL responses 10 3

100109 1-G-W13-4-O/P Takao SudoDepartment of Immunology and Cell Biology, Osaka University

Graduate School of Medicine, Osaka, JapanStressed microenvironment induced by 5-FU promotes the proliferation of HSPC in bone marrow 6 2

100496 1-G-W13-6-O/P Yukiko DoiDepartment of Hematology and Oncology, Osaka University Graduate

School of Medicine, Suita, Osaka, Japan

SATB1 expression is useful to identify the lymphoid-lineage-biased trajectory of functionally fluctuating

hematopoietic stem cells. 6 2

100312 1-G-W13-7-O/P Junichiro TakanoLaboratory for Immune Regeneration, RIKEN Center for Integrative

Medical Sciences, Yokohama, Japan

Varinat PRC1.1 is required for specification of hematopoietic progenitor cells toward B

lymphoid lineage 6 2

100204 1-G-W13-8-O/P Yohei KawanoDepartment of Immune Regulation, Tokyo Medical and Dental

Universiy Graduate School, Tokyo, Japan

Establishment of a novel culture system for long-term proliferating hematopoietic progenitors with

lymphoid and myeloid potential from normal mouse bone marrow without genetic manipulations 6 2

100551 1-G-W13-9-O/P Tatsuya ShishidoDepartment of Immunochemistry, Research Institute for Microbital

Disease, Osaka UniversityCrucial role of CD74 in hematopoietic cell differentiation 6 2

100336 1-G-W13-10-O/P Masashi KanayamaDepartment of Immunology, Duke University School of Medicine,

Durham, North Carolina, USA.Balancing population sizes of myeloid and lymphoid cells by osteopontin isoforms 6 2

100241 1-G-W13-12-O/P Akihisa OdaResearch Institute for Biomedical Sciences Tokyo Universitiy of

Science, Chiba, Japan

Niche-induced myeloproliferative-like disease caused by overexpression of Tlx1 in situ

in splenic stromal cells 6 2

100097 1-G-W13-16-O/P Yasuyuki SaitoDivision of Molecular and Cellular Signaling, Department of

Biochemistry and Molecular Biology, Kobe University Graduate

School of Medicine, Kobe, Japan

SIRPα+ dendritic cells regulate homeostasis of fibroblastic reticular cells via TNF

receptor ligands in the adult spleen 6 2

100367 1-G-W13-17-O/P Kazuki SatoDepartment of Immunology, Faculty of Medicine, University of

Tsukuba, Ibaraki, JapanMarginal reticular cells act as a non-professional phagocyte for clearance of apoptotic B cells 6 2

100302 1-G-W13-18-O/P Arata TakeuchiDepartment of Immunology, Graduate School of Medical and Dental

Sciences, Niigata University, Niigata, Japan

Six different types of mesenchymal stromal cells provide the framework of multi-layered

subcompartments in lymph node 6 2

Takashi

Nagasawa

Hitoshi

TakizawaW13

Hematopoiesis

and immune

environments

Dec. 12

(Tue.), 201713:20 14:40 Room G

Toshihiko

Torigoe

Kenichiro

SeinoW12

Immune

responses in

cacer

immunotherapy

Dec. 12

(Tue.), 201714:55 16:15 Room F

Hiroyoshi

Nishikawa

Yoshihiro

HayakawaW11

Combination

cancer

immunothrapy -

beyond immune

checkpoint

inhibitors-

Dec. 12

(Tue.), 201713:20 14:40 Room F

Kazuyoshi

Kawakami

Hiromitsu

HaraW10

Immune

response to

mycobacteial

and fungal

infections

Dec. 12

(Tue.), 201714:55 16:15 Room E

4 / 12

100347 1-H-W15-1-O/P Kentaro Asayama Dept of ImmunologyA novel mouse model of spontaneous lung cancer caused by lung TGF-β1

overexpression 6 2

100483 1-H-W15-2-O/P Mayu KaetsuDepartment of Life Science and Medical Bioscience, Waseda

University, Tokyo, JapanColonic inflammation induces a transient increase in serum LECT2 level. 6 2

100411 1-H-W15-3-O/P Wooseok SeoRIKEN IMS Center for Integrative Medical Sciences,Yokohama,

JapanRegulation of CCL5 expression by Runx complexes and two stage-specific enhancers 6 2

100508 1-H-W15-4-O/P Sunyi JooDivision of Mucosal Immunology, Department of Microbiology and

Immunology, The Institute of Medical Science, The University of

Tokyo, Japan

Critical role of the CCR5-CCL5 cascade for the preferential migration of HSV-2-specific

effector cells to the vaginal mucosa upon intranasal immunization 6 2

100107 1-H-W15-5-O/P Mizuho NosakaDepartment of Forensic Medicine, Wakayama Medical University,

Wakayama, Japan

Absence of CCR5 axis exaggerates thrombus formation through reduced uPA, tPA and VEGF

expression in murine DVT mode 6 2

100061 1-H-W15-6-O/P Masaaki KawanoDepartment of Allergy and Immunology, Faculty of Medicine, Saitama

Medical University, Saitama, JapanDopamine fluctuates cytokine secretion in innate and adaptive immune responses 6 2

100150 1-H-W15-7-O/P Keiko YoshimotoDivision of Rheumatology, Department of Internal Medicine, Keio

University School of Medicine, Tokyo, Japan

BAFF signaling inhibitors ameliorate enhanced production of IL-6 and IL-10 by pSS monocytes and

consequently suppress IgG overproduction by affecting differentiation of B cells. 6 2

100309 1-H-W15-8-O/P Mizoguchi IzuruDepartment of Immunoregulation, Institute of Medical Science, Tokyo

Medical University, Tokyo, Japan

A Novel Role for Epstein-Barr Virus-Induced Gene 3 to Augment IL-23 Receptor

α Protein Expression through A Lectin Chaperone Calnexin

6 2

100625 1-H-W15-9-O/P Hironao SuzukiDivision of Psychoimmunology, Institute for Genetic Medicine,

Hokkaido University, Hokkaido, Japan

RNA Splicing Mediator 1 (RSM1) regulates inflammation via alternative splicing of DNA

methyltransferase Dnmt3b 6 2

100534 1-H-W16-1-O/P Kazuo OkamotoDepartment of Osteoimmunology, Graduate School of Medicine and

Faculty of Medicine, The University of Tokyo, Tokyo, JapanA distinct role of an EF-hand motif protein in the hematopoietic cell lineage 6 2

100279 1-H-W16-2-O/P Koki HirashimaDepartment of immunology, Graduate School of Pharmaceutical

Sciences, Hokkaido UniversityTyk2 positively regulates P. acnes-induced acute inflammation 6 2

100007 1-H-W16-3-O/P Takashi IzawaDepartment of Orthodontics and Dentofacial Orthopedics, Tokushima

University Graduate School of Biomedical Sciences, Tokushima,

Japan

Crosstalk between cytokine RANKL and AhR signaling in osteoclasts controls bone homeostasis 6 2

100146 1-H-W16-4-O/P Yurina Miyajima Laboratory for Innate Immune Systems, RIKEN IMS Function of BMP2 and BMP7 produced by ILC2 in the adipose tissue 6 2

100308 1-H-W16-5-O/P Ippei KoshiDepartment of Molecular and Cellular Immunology, Shinshu

University Graduate School of Medicine

Branching cytokine signals for an effector function and cell survival via a discrete common β

chain subregion in murine primary basophils 6 2

100318 1-H-W16-6-O/P Yuki HikichiLaboratory for Innate Immune Systems, RIKEN Center for Integrative

Medical SciencesPost-transcriptional regulation of type 2 cytokine gene expression in ILC2 6 2

100663 1-H-W16-7-O/P Natsuo Yamamoto Department of Infection Control Anti-inflammatory effects on liver cells with flavonoids during rapid phgase in a severe sepsis 6 2

100477 1-H-W16-8-O/P Jae-won ChangGraduate School of Frontier Sciences, The University of Tokyo,

Chiba, Japan

The first distinction and observation of single molecular dynamics between Interleukin-2 with

Intereleukin-2 receptor and Interleukin-15 with Interleukin-15 receptor through Diffracted X-ray

Tracking6 2

100104 1-H-W16-9-O/P Kazuko Uno Louis Pasteur Center for Medical ResearchUsing non-negative matrix factorization analysis of IFN/Cytokine production and those of serum levels

to identify groups at high-risk of disease or those in the early stages of disease 6 2

100010 1-I-W17-1-O/P Yuki HitomiDepartment of Human Genetics, Graduate School of Medicine, the

University of Tokyo, Tokyo Japan

Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility

gene loci NFKB1/MANBA 7 3

100297 1-I-W17-3-O/P Ryutaro IWABUCHIDepartment of Life Science and Medical Bioscience, Waseda


Human GM-CSF and Flt3-L induce reconstitution and maturation of human myeloid dendritic cells in

humanized mice 7 3

100643 1-I-W17-13-O/P Fumiko HONDA-OZAKICenter for Stem Cell Biology and Regenerative Medicine Institute of

Medical Science University of Tokyo

Evaluation of the Utility of Induced Pluripotent Stem Cells as a platform for modeling Wiskott Aldrich

Syndrome 7 3

100180 1-I-W17-14-O/P Daisuke SUZUKICenter for iPS Cell Research and Application, Kyoto University,

Kyoto, Japan

Differential natural killer (NK) cell immunity against class-I human leukocyte antigen (HLA)-knockout

(KO) platelets and megakaryocytes 7 3

100154 1-I-W17-15-O/P Iwamoto SanjuDivision of Physiology and Pathology, Department of Pharmacology,

Toxicology and Therapeutics, Showa University of Pharmacy, Tokyo,

Japan

Atypical development of human Th17 lineage from naïve CD4 T cells in psoriasis. 7 3

100278 1-I-W17-16-O/P Nozomi Kuse Center for AIDS Research, Kumamoto University, Kumamoto, JapanEffective priming of functional HIV-1-specific CD8+ T Cells from naïve T

cells using STING ligand 7 3

100403 1-I-W17-18-O/P Iyoda Tomonori RIKEN Center for Integrative Medical Sciences, Yokohama, JapanImprovement of NK cell function against multiple myeloma cells by an adjunctive effect of activated

invariant natural killer T (NKT) cells 7 3

100662 1-I-W17-23-O/P Kayoko SatoDepartment of Cardiology, Tokyo Women's Medical University,

Tokyo, Japan

Dipeptidyl peptidase 4 (DPP-4) signaling in T cells contributes atherosclerotic development and

podocyte dysfunction 7 3

Koji Yasutomo Keishi FujioW17Human

Immunology

Dec. 12

(Tue.), 201713:20 14:40 Room I

Takayuki

Yoshimoto

Takashi

KobayashiW16

Cytokines and

chemokines-2

Dec. 12

(Tue.), 201714:55 16:15 Room H

Masaaki

Murakami

Akihiro

KimuraW15

Cytokines and

chemokines-1

Dec. 12

(Tue.), 201713:20 14:40 Room H

5 / 12

100042 1-I-W18-1-O/P Soh Yamazaki Department of Biochemistry, Toho University School of Medicine The AP-1 transcription factor JunB is essential for development of Th17 cells 7 3

100082 1-I-W18-2-O/P SHINYA TANAKAResearch Institute for Biomedical Sciences, Tokyo University of


Tripartite motif-containing 33 (Trim33) mediates a pro-inflammatory phenotype of Th17

cells. 7 3

100620 1-I-W18-3-O/P Keiko YasudaLaboratory of Experimental Immunology, Institute for Frontier Life and

Medical Sciences, Kyoto University, Kyoto, JapanSatb1 controls the differentiation and terminal effector function of Th17 cells 7 3

100207 1-I-W18-4-O/P Yuko OkuyamaDepartment of Microbiology and Immunology, Tohoku University

Graduate School of Medicine, Miyagi, Japan

A new regulator of OX40 co-signaling controls autoimmune neuroinflammation mediated by

CD4+ T cells 7 3

100009 1-I-W18-7-O/P Kota KokuboDepartment of Immunology, Graduate School of Medicine, Chiba

University, Chiba, Japan

Menin controls the memory Th2 cell function by maintaining the epigenetic integrity of Th2

cells. 7 3

100320 1-I-W18-8-O/P Makoto KuwaharaDepartment of Immunology, Graduate School of Medicine, Ehime

University, Ehime, JapanThe transcriptional repressor Bach2 regulates differentiation of pathogenic Th2 cells 7 3

100543 1-I-W18-9-O/P Harada YasuyoResearch Institute for Biomedical Science, Tokyo University of


Role of follicular helper T cells and TH2 cells in IgE mediated active

cutaneous anaphylaxis 7 3

100413 1-I-W18-10-O/P Masaki Tajima Laboratory of Host Defenses, NIAID, NIH, Maryland, USAIL-10-Producing Tr2 cells Induced by mTOR/CEBPβ Signaling Regulate Hyphal

C. albicans Kidney Infection 7 3

100381 2-A-W19-3-O/P Daisuke Takahashi Keio University Faculty of Pharmacy, Tokyo, Japan Microbial fermentation product butyrate Ameliorates Autoimmune Arthritis. 7 3

100499 2-A-W19-5-O/P Kiyoshi HiraharaDepartment of Immunology, Graduate School of Medicine, Chiba

University

Memory-type ST2+CD4+ T cells participate in the steroid-resistant

pathology of eosinophilic pneumonia 7 3

100117 2-A-W19-8-O/P Takahiro NagatakeLaboratory of Vaccine Materials and Laboratory of Gut Environmental

System, National Institutes of Biomedical Innovation, Health and

Nutrition (NIBIOHN), Osaka, Japan

17,18-EpETE, a metabolite of omega-3 essential fatty acids, inhibited neutrophil mobility and

ameliorated skin inflammation in DNFB-induced contact hypersensitivity model 7 3

100258 2-A-W19-9-O/P Emi FurusawaDepartment of Molecular Immunology , Tokyo Medical and Dental

University,Tokyo,JapanSilencing of B7-DC/PD-L2 in the cutaneous dendritic cells using siRNA inhibits contact allergy 7 3

100090 2-A-W19-11-O/P Tomohiro FUKAYADivision of Immunology, Department of Infectious Diseases, Faculty

of Medicine, University of MiyazakiCritical role of IL-22 binding protein in the control of skin inflammation 7 3

100264 2-A-W19-14-O/P Mari TennoDepartment of Immune Regulation Research Institute National

Center for Global Health and Medicine, Chiba, JapanDisruption of Lnk increases severity of dextran sulfate sodium-induced acute colonic inflammation 7 3

100128 2-A-W19-16-O/P Yuki UsuiDivision of Systems Immunology, Institute of Medical Science, The

University of TokyoMaintenance of intestinal barrier function by long-term intake of LB81 yogurt 7 3

100067 2-A-W19-17-O/P Chiao-Ching HsuLaboratory of Immune Regulation, Graduate School of Medicine,

Osaka University, Japan

Human LYPD8 protein has motility inhibitory functions to pathogenic flagellated

bacteria 7 3

100034 2-B-W20-1-O/P Sumie HiramatsuDepartment of Nephrology, Rheumatology, Endocrinology and

Metabolism, Okayama University Graduate School of Medicine,

Dentistry and Pharmaceutical Sciences, Okayama, Japan.

DNA Methylation-dependent regulation of Cathepsin E gene expression by the transcription factor

Kaiso in MRL/lpr mice. 7 3

100012 2-B-W20-2-O/P Takeshi MachidaDepartment of Immunology, Fukushima Medical University,

Fukushima, Japan

Significant role for splenic marginal zone B cells in anti-dsDNA autoantibody production in

lupus-prone mice with an MRL background 7 3

100131 2-B-W20-4-O/P Takamasa ChoDivision of Clinical Nephrology and Rheumatology,Niigata University,

Niigata,JapanAnti-ribosomal-P antibody induces psychosis and hepatitis 7 3

100096 2-B-W20-6-O/P Sonia ZeggarDepartment of Nephrology,Rheumatology,Endocrinology and

Metabolism,Okayama University graduate school of

medecine,Okayama,Japan

Lgals9 deficiency attenuates nephritis and arthritis in pristane induced mice model of SLE 7 3

100196 2-B-W20-7-O/P Shin-Ichiroh SaitohThe Institute of Medical Science, The University of Tokyo, Tokyo,

Japan.

ADP-libosylation factor-like 8b is required for pathogenesis of mouse models of Systemic Lupus

Erythematosus 7 3

100119 2-B-W20-9-O/P Norio HanataDepartment of Allergy and Rheumatology, Graduate School of

Medicine, The University of Tokyo, Tokyo, JapanThe effects of peptidylarginine deiminase 4 in imiquimod-induced lupus model mice. 7 3

100348 2-B-W20-10-O/P Masahiro NakashimaImmunology and Microbiology, National Defense Medical College,

Tokorozawa, Japan

Repeated administrations of α-galactosylceramide slow the progression of lupus nephritis in

BWF1 mice 7 3

100544 2-B-W20-12-O/P Takuto OhkiDivision of Psychoimmunology, Institute for Genetic Medicine,

Graduate School of Medicine, Hokkaido University

Symmetric-Gateway Reflex, which develops symmetrical inflammation

between joints is induced by the specific sensory pathway in a rheumatoid arthritis model 7 3

100443 2-C-W21-1-O/P Kiyomi SHITAOKADepartment of Innovative Cancer Immunotherapy, Graduate School of

Medicine and Pharmaceutical Sciences, University of Toyama,

Toyama City, Japan

Majority of tumor infiltrating lymphocytes in B16F10 melanoma recognized tumor-associated antigens,

but not melanoma-associated antigens or neoantigens. 10 3

100328 2-C-W21-6-O/P Satomi OkadaDepartment of Oncology, Nagasaki University Graduate School of

Biomedical Sciences, Nagasaki, Japan

Development of TCR gene therapy with allogeneic “Stealth T cells” deficient in

endogenous TCR and HLA class I molecules 10 3

100327 2-C-W21-7-O/P Ngoc M PhamDepartment of Surgery, Shiga University of Medical Science, Otsu,

Japan

Co-stimulation via OX40 signal in vitro to generate tumor antigen-specific CTLs for

adoptive cell transfer therapy 10 3

100571 2-C-W21-8-O/P Raul VizcardoSurgery Branch, National Cancer Institute, National Institutes of

Health, Bethesda MD, USADeveloping the next generation of iPSC cell-based immunotherapies 10 3

100503 2-C-W21-9-O/P Seiji Nagano Institute for Frontier Life and Medical Sciences, Kyoto UniversityiPSCs transduced with TCR gene give rise to potent CTLs with antigen specific cytotoxic

activity comparable to those from T-iPSCs 10 3

100646 2-C-W21-12-O/P Yoshihiro MiyaharaDepartment of Immuno-Gene Therapy, Mie University Graduate

School of Medicine, Mie, Japan

A novel CAR-T therapy targeting MAGE-A4p230-239/HLA-A*02:01 complex for solid

tumors 10 3

Hiroaki Ikeda Koji TamadaW21Cancer Cell

Therapy

Dec. 13

(Wed.), 201714:25 15:45 Room C

Hitoshi

Kohsaka

Shinsuke

YasudaW20

Systemic

autoimmune

disease (1)

Dec. 13

(Wed.), 201714:25 15:45 Room B

Kenji

Kabashima

Yoshiyuki

GotoW19

Mucosal-Skin

Immunity-1

Dec. 13

(Wed.), 201714:25 15:45 Room A

Masakatsu

YAMASHITA

Motoko Y.

KIMURAW18 Helper T cells

Dec. 12

(Tue.), 201714:55 16:15 Room I

6 / 12

100062 2-F-W22-1-O/P Yoichi SutohIwate Tohoku Medical Megabank Organization, Iwate Medical

University, Yahaba, Japan

Origin of thymic selection inferred from the deviated antigen receptor usage in

lamprey 8 3

100184 2-F-W22-2-O/P Katsuto Hozumi Tokai University School of Medicine, Isehara, JapanMolecular machinery for the maintenance of differentiation potential toward T/B cell lineages in

hematopoietic stem/progenitor cells by Lmo2 8 3

100101 2-F-W22-5-O/P Satoshi Kojo Lab. for Transcriptional Regulation, RIKEN IMS, Yokohama, JapanRegulation of Runx3 activity in immune system development by the C-terminal end amino acid

sequence 8 3

100091 2-F-W22-7-O/P Kenta KondoInstitute of Advanced Medical Sciences, University of Tokushima,

Tokushima, Japan.

Thymoproteasome-dependent positive selection conditions in vivo immune responses in

CD8+ T cells 8 3

100538 2-F-W22-8-O/P Takeshi Nitta Department of Immunology, The University of Tokyo, Tokyo, Japan Human thymoproteasome variations influence CD8 T cell repertoire 8 3

100134 2-F-W22-10-O/P Kazumasa KanekoGraduate School of Engineering, The University of Tokyo, Tokyo,

JapanMathematical modeling of thymic T cell development via interaction with thymic epithelial cells 8 3

100019 2-F-W22-14-O/P Osamu Kaminuma Center for Life Science Research, University of Yamanashi Establishment of non-transgenic monoclonal T cell receptor-expressing mice 8 3

100050 2-G-W23-1-O/P Kazuhiko YamamuraDepartment of Dermatology, Graduate School of Medical Sciences,

Kyushu University, Fukuoka, JapanThe transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction 10 3

100058 2-G-W23-2-O/P Akihiko MurataDivision of Immunology, Department of Molecular and Cellular

Biology, School of Life Science, Faculty of Medicine, Tottori

University, Japan

Local skin memory response in contact dermatitis involves tissue resident memory T cells 10 3

100164 2-G-W23-3-O/P Seiji KamijoAtopy (Allergy) Research Center, Juntendo University Graduate


Protease allergen-induced local IL-17A production in skin tissue and accumulation of IL-

17A+ γδ T cells in skin draining lymph nodes; possible contribution to

enhancement of skin eosinophilia and serum IgE response10 3

100400 2-G-W23-5-O/P Kazumasa KanemaruDepartment of Immunology, Faculty of Medicine, University of

Tsukuba, Ibaraki, JapanClec10a suppresses house dust mite-induced dermatitis 10 3

100664 2-G-W23-13-O/P Yoshinori YamanishiDepartment of Immune Regulation, Graduate School of Medical and

Dental Sciences, Tokyo Medical and Dental University (TMDU),

Tokyo, Japan

Basophil tryptase mMCP-11 plays a crucial role in IgE-mediated, delayed-onset allergic inflammation 10 3

100081 2-G-W23-15-O/P MAYUMI UETADepartments of Frontier Medical Science and Technology for

Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto,

Japan

Difference in the tear cytokines between chronic Stevens-Johnson syndrome patients and Atopic

keratoconjunctivitis 10 3

100481 2-H-W24-1-O/P Miwa SasaiDepartment of Immunoparasitology, Research Institute for Microbial

Diseases, Osaka University, Osaka, Japan

Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses

against T. gondii infection 7 3

100168 2-H-W24-2-O/P Mana MiyakodaDivision of Immunology, Department of Molecular Microbiology and

Immunology, Graduate School of Biomedical Sciences, Nagasaki

University

Mechanisms underlying metformin-mediated enhancement of the protective immune responses

against malaria infection. 7 3

100238 2-H-W24-4-O/P Sayuri NakamaeDivision of Immunology, Department of Molecular Microbiology and

Immunology, Nakgasaki University Graduate School of Biomedical

Sciences, Nagasaki, Japan

Modulation of T-cell immune responses to pathogenic malaria parasites by prior infection with different

species of malaria parasites 7 3

100549 2-H-W24-7-O/P Fumiji SaitoResearch Institute for Microbial Diseases, Osaka University, Osaka,

Japan

Immune evasion of Plasmodium falciparum by RIFIN via

inhibitory receptor 7 3

100206 2-H-W24-10-O/P Odsuren SukhbaatarDepartment of Molecular Microbiology and Immunology, Nagasaki

University Graduate School of Biomedical Science, Nagasaki, JapanRole of Interleukin-27 in the regulation of immune responses against chronic malaria infection 7 3

100580 2-H-W24-11-O/P Piyarat SrinontongDepartment of Parasitology and Infectious Diseases, Gifu University

Graduate School of Medicine, Gifu, JapanRegulation of Visceral Leishmaniasis by Secreted Immunoglobulin Deficiency 7 3

100219 2-H-W24-12-O/P Shin-Ichi InoueDepartment of Infectious Diseases, Kyorin University School of


Maintenance of immunological memory to malaria is impaired by Salmonella

infection 7 3

100018 2-I-W25-1-O/P Tomofumi UtoDivision of Immunology, Department of Infectious Diseases, Faculty

of Medicine, University of Miyazaki, Miyazaki, Japan

Critical role of plasmacytoid dendritic cells in the induction of oral tolerance for the control of allergic

sensitization 7 3

100368 2-I-W25-2-O/P Alessandro Nasti System Biology, Kanazawa University, Kanazawa, Japan

The CD45+ subset in murine uncultured adipose tissue-derived stromal cells

features immune-inhibitory M2 macrophage-like cells contributable for

therapeutics of acute h7 3

100094 2-I-W25-3-O/P Hisako Kayama Graduate School of Medicine, Osaka University, Suita, JapanSpi-C inhibits expression of a subset of Toll-like receptor 4-inducible genes in intestinal

CX3CR1high macrophages and prevents colonic inflammation 7 3

100607 2-I-W25-4-O/P Keita AoiDepartment of Immunology and Cell Biology, Graduate School of

Medicine / Frontier Biosciences, Osaka University, Osaka, Japan

Oral mucosa-specific macrophage subsets contribute to tolerance induction in sublingual

immunotherapy 7 3

100065 2-I-W25-5-O/P Sho SendoDepartment of Rheumatology and Clinical Immunology, Kobe

University Graduate School of Medicine, Kobe, Japan.

CD11b+Gr1dim Tolerogenic Dendritic Cell-like Cells Differentiated

from Monocytic-MDSCs Suppress the Progression of Interstitial Lung Disease in SKG Mice 7 3

100459 2-I-W25-6-O/P Yoshimitsu NakanishiDepartment of Respiratory Medicine and Clinical Immunology,

Graduate School of medicine, Osaka University, Osaka, Japan

Sema6D prevents excess inflammation during high-fat feeding by controlling mitochondrial

metabolism. 7 3

100555 2-I-W25-12-O/P Matsumoto MinoruDivision of Molecular Immunology, Institute for Enzyme Research,

Tokushima University, Tokushima, Japan

Transgenic human AIRE expression in NOD acquired resistance to the diabetes due to the impaired

presentation of self-antigens in the pancreas 7 3

100550 2-I-W25-13-O/P Yuta ShimizuDepartment of Immunochemistry, Research Institute for Microbial

Disease, Osaka University, Laboratory of ImmunochemistryChemical compounds that specifically inhibit aberrant MHC class II expression 7 3

Satoshi IshidoKenichi

AsanoW25

Dendritic cells

and

Macrophages-1:

Organ-specific

Immune

Tolerance

Dec. 13

(Wed.), 201714:25 15:45 Room I

Yoichi

Maekawa

Masahiro

YamamotoW24

Immune

response to

parasite

infections

Dec. 13

(Wed.), 201714:25 15:45 Room H

Kenji IzuharaTomohiro

YoshimotoW23

Allergy-3 :

Allergic

dermatitis, food

allergy and

allergic

conjunctivitis

Dec. 13

(Wed.), 201714:25 15:45 Room G

Taishin

AkiyamaTakeshi NittaW22

T cell-1: T cell

development

and repertoire

selection

Dec. 13

(Wed.), 201714:25 15:45 Room F

7 / 12

100233 3-A-W26-1-O/P Takumi MaruhashiDivision of Immune Regulation, Institute for Genome Research,

Tokushima University, Tokushima, Japan

Immuno-inhibitory co-receptor LAG-3 regulates immunodominance and autoimmunity by virtue of its

conformation-dependent recognition of MHCII 10 3

100251 3-A-W26-2-O/P Hikari OkamuraDivision of Immune Regulation, Institute for Genome Research,

Tokushima UniversitySingle-cell analysis of autoreactive T cells under the control of PD-1 10 3

100166 3-A-W26-4-O/P Daisuke KimuraDivision of Immunology, Department of Molecular Microbiology and

Immunology, Nagasaki University Graduate School of Biomedical

Sciences, Nagasaki, Japan

Interleukin-27-dependent loss of CD4+ T cell-memory during malaria infection 10 3

100130 3-A-W26-5-O/P Shigenori NagaiDepartment of Molecular Immunology, Tokyo Medical and Dental

University, Tokyo, JapanPI3K-Akt pathway enhances type 1 regulatory T cell differentiation induced by IL-27 10 3

100536 3-A-W26-9-O/P Xiaotong CuiLaboratory of Infection and Prevention, Department of Virus

Research, Institute for Frontier Life and Medical Sciences, Kyoto

University, Kyoto, Japan

Interactions between Regnase-1 and Roquin Regulate Helper T Cell Polarization 10 3

100562 3-A-W26-10-O/P Kazuki KishidaDepartment of Immunochemistry, Research Institute for Microbial

Diseases, Osaka UniversityAntigen-specific immune regulation mediated by TCR-like antibodies 10 3

100516 3-A-W27-1-O/P Ryoji KawakamiImmunology Frontier Research Center, Osaka university, Osaka,

JapanEpigenomic signatures of extrathymic-derived regulatory T-cells 10 3

100589 3-A-W27-4-O/P Yumi Yamashita-KanemaruDepartment of Immunology, Faculty of Medicine, University of

Tsukuba, Tsukuba, Ibaraki, JapanDNAM-1 limits Treg cell function via TIGIT-dependent manner 10 3

100389 3-A-W27-7-O/P Yoshiaki Yasumizu Faculty of Medicine, Osaka University, Osaka, Japan Significance of the regulatory T cell-specific epigenetics in autoimmune disease susceptibility 10 3

100578 3-A-W27-10-O/P Chikako ShimokawaDepartment of Parasitology, Graduate School of Medicine, Gunma

University, GunmaSuppression of type 1 diabetes in mice infected with an intestinal nematode 10 3

100030 3-A-W27-14-O/P Hiroki SatookaDepartment of Fundamental Biosciences, Shiga University of Medical

Science, Shiga, Japan

The ERM protein moesin regulates CD8+ regulatory T cell homeostasis and self-

torelance 10 3

100564 3-A-W27-15-O/P Reiko Takahashi Research Institute Nozaki Tokushukai, Daitou, JapanInhibition of melanoma proliferation by immunologic mechanism including the plasticity of SOCS1

deficient regulatory T cells 10 3

100334 3-B-W28-1-O/P Shinya HatanoDivision of Host Defense, Medical Institute of Bioregulation, Kyushu

University, Fukuoka, Japan.Development of new monoclonal antibody specific for murine Vγ6 chain 11 2

100075 3-B-W28-2-O/P Tsukasa NabekuraLife Science Center, Tsukuba Advanced Research Alliance,

University of Tsukuba, Ibaraki, Japan

Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus

infection 11 2

100395 3-B-W28-4-O/P Eri IshikawaDepartment of Molecular Immunology, Research Institute for

Microbial Diseases, Osaka University, Osaka, JapanA critical role of protein kinase D in NKT cell development 11 2

100286 3-B-W28-5-O/P Hiroshi WataraiDivision of Stem Cell Cellomics, Institute of Medical Science,

University of Tokyo

A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Technology

Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease 11 2

100060 3-B-W28-11-O/P Goh MurayamaDepartment of Immunology, Juntendo University School of Medicine,

Tokyo, JapanRole of mucosal-associated invariant T cells in lupus pathogenesis 11 2

100392 3-B-W28-12-O/P Asako Chiba Department of Immunology, Juntendo University, Tokyo, Japan MAIT cells exacerbate the disease course of oxazolone colitis. 11 2

100566 3-B-W29-1-O/P Takashi EbiharaLaboratory for Transcriptional Regulation, RIKEN Center for

Integrative Medical SciencesRunx proteins suppress constitutive activity of ILC2 and prevent ILC2 exhaustion after activation 11 2

100047 3-B-W29-4-O/P Takanori SoDepartment of Microbiology and Immunology, Tohoku University

Graduate School of Medicine, Sendai, Japan

Early activation of group 2 innate lymphoid cells in the lung is critically controlled by the TNFR

superfamily molecule GITR 11 2

100147 3-B-W29-5-O/P Natsuko Otaki Laboratory for Innate Immune Systems, RIKEN IMS The role of group 2 innate lymphoid cells in pulmonary fibrosis 11 2

100446 3-B-W29-7-O/P Naoko SatohLaboratory for Intestinal Ecosystem, Center for Integrative Medical

Science, RIKEN

Identification of an ILC2 population in the stomach which responds to commensal and pathogenic

bacteria 11 2

100476 3-B-W29-8-O/P Takato Kobayashi Laboratory for Innate Immune Systems, RIKEN IMS Characterization of group 2 innate lymphoid cells in glandular tissue 11 2

100468 3-B-W29-9-O/P Mariko KamiokaDivision of Mucosal Immunology, Department of Microbiology and


Tokyo, Tokyo, Japan

Innate and adaptive immune cells regulate Paneth cell granule formation and α-defensin

secretion 11 2

Susumu

NAKAE

Shinichiro

SAWAW29

Innate

Lymphocyte-2

(ILC1,2,3)

Dec. 14

(Thu.), 201714:25 15:45 Room B

Kensuke

Shibata

Kazuya

IWABUCHIW28

Innate

Lymphocyte-1

(NKT, MAIT,

gdT, NK)

Dec. 14

(Thu.), 201712:50 14:10 Room B

Naganari

Ohkura

Takashi

SekiyaW27

Tolerance and

immune

suppression -2

Dec. 14

(Thu.), 201714:25 15:45 Room A

Taku OkazakiShunsuke

ChikumaW26

Tolerance and

immune

suppression -1

Dec. 14

(Thu.), 201712:50 14:10 Room A

8 / 12

100237 3-C-W30-1-O/P Jeong-Hwan YoonBiomedical Research Institute, Kyungpook National University

Hospital, Daegu, KoreaRepression of SMAD3 by STAT3 and c-SKI is essential for conventional dendritic cell differentiation 7 3

100240 3-C-W30-2-O/P Haruka SasakiDepartment of Immunology, Yokohama City University Graduate

School of Medicine, Yokohama, Japan

A novel distal enhancer responsible for Irf8 expression in the mononuclear phagocyte

lineage 7 3

100622 3-C-W30-3-O/P Nobuyuki OnaiDepartment of Immunology, Kanazawa Medical University, Ishikawa,

JapanRegulation of pDC development by graded expression of E2-2 7 3

100290 3-C-W30-9-O/P Ryo OkadaDept. of integrated Biosciences, Grad. school of frontier Sciences,

The university of Tokyo, Tokyo, JapanDistribution of DCIR4 among various tissue-resident macrophages 7 3

100369 3-C-W30-10-O/P Naoki MatsumotoGraduate School of Frontier Sciences, the University of Tokyo, Chiba,

JapanCo-expression of DCIR3 and DCIR4 on monocytes 7 3

100500 3-C-W30-11-O/P Miyuki WatanabeDepartment of Molecular Immunology, Research Institute for

Microbial Diseases, Osaka University, Osaka, Japan

Early FcRγ-Erk signaling determines cytokine profile of dendritic cells through C-type lectin

receptors 7 3

100402 3-C-W30-12-O/P Shojiro HajiDepartment of Molecular Immunology, Division of Host Defense,

Research Institute for Microbial Diseases, Osaka University, Osaka,

Japan

Recognition of lipids from Helicobacter pylori by dendritic cell immunoactivating receptor

(DCAR). 7 3

100214 3-C-W30-13-O/P Masafumi NakayamaFrontier Research Institute for Interdisciplinary Sciences, Tohoku

UniversityIdentification of a silica receptor associated with canonical inflammasome activation. 7 3

100033 3-C-W31-5-O/P Tanapat PalagaDepartment of Microbiology, Faculty of Science, Chulalongkorn

University, Bangkok, ThailandNotch Signaling Regulates Macrophages Activation by LPS in the Presence of Immune Complex 8 3

100148 3-C-W31-6-O/P Sayako ChibaDivision of Gastroenterology and Hepatology, Department of Internal

Medicine, Keio University School of Medicine, Tokyo, JapanGlycolysis regulates LPS-induced cytokine production in M2 polarized human macrophages 8 3

100149 3-C-W31-7-O/P Akihiro KimuraDept. of Immunology and Pathology, Research Institute National

Center for Global Health and Medicine, Chiba, Japan

The novel ubiquitin ligase complex, NQO1-PDLIM2 inhibits TLR-dependent production of

selective cytokines by degrading IκB-ζ 8 3

100252 3-C-W31-8-O/P Rimpei MORITADepartment of Immunology, International University of Health and

Welfare, School of Medicine, Narita, JapanClathrin heavy chain is an NLRP3 partner for NLRP3 inflammasome activation 8 3

100167 3-C-W31-9-O/P Takuya YashiroDepartment of Biological Science and Technology, Faculty of

lndustrial Science and Technology, Tokyo University of Science,

Tokyo, Japan

Defect of NR4A3 leads to impaired ability of migration in intestinal dendritic cells 8 3

100208 3-C-W31-12-O/P Takeshi NakataniDepartment of respiratory medicine and clinical immunology, Osaka

Univ., Osaka, JapanLamtor1 (p18) plays a crucial role in trafficking of dendritic cells. 8 3

100475 3-C-W31-15-O/P Takumi Kawasaki Nara Institute of Science and Technology (NAIST), Nara, Japan Obesity regulation by PIKfyve, a lipid kinase, in macrophage 8 3

100190 3-D-W32-1-O/P Yasuhiro KikuchiDepartment of Pathology, Sapporo Medical University School of

Medicine, Sapporo, JapanA novel HLA class I peptide encoded by a long non-coding RNA 7 3

100362 3-D-W32-4-O/P Yoh OhnukiDepartment of Immunology, Graduate School of Medicine and

Pharmaceutical Sciences, University of Toyama, 2630 Sugitani,

Toyama 930-0194, Japan

The model of antigen detection system using yeast surface display library 7 3

100626 3-D-W32-6-O/P Keisuke FujiiDepartment of Immuno-Gene Therapy, Mie University Graduate

School of Medicine, Mie, Japan

Phenotypic and clonality analysis of tumor-reactive CD8+ T cells among TILs in human

colorectal tumor tissue 7 3

100507 3-D-W32-7-O/P Taiki MoriyaLaboratory of Immunology, Faculty of Pharmacy, Osaka Ohtani

University, Osaka, Japan

Tumor cell death induction enhances tumor infiltrating dendritic cell migration and increases in tumor

antigen-specific T cells. 7 3

100038 3-D-W32-9-O/P Takuto NosakaSecond Department of Internal Medicine, Faculty of Medical

Sciences, Fukui University, Eiheiji-machi, Japan

Alveolar macrophages drive hepatocellular carcinoma lung metastasis in collaboration with

interstitial macrophages 7 3

100421 3-D-W32-10-O/P Risa FujiiDepartment of Anatomy and Embryology, Faculty of medicine,

University of Tsukuba, Tsukuba, Japan

MafB inhibits tumor growth through regulating Tumor-Associated

–Macrophages in spleen 7 3

100186 3-D-W32-11-O/P Hisashi KanemaruResearch Institute for Microbial Diseases (RIMD), Osaka University,

Osaka, Japan

Basic leucine zipper transcription factor ATF-like 2 exhibits an anti-tumor effect through upregulation of

IL-12 p40 expression 7 3

100469 3-D-W32-14-O/P Hiroshi HIGUCHI School of Medicine, Tokai University, Kanagawa, JapanPhosphatidylserine-mediated incorporation of tumor-derived exosomes and phenotypic changes in

human macrophages 7 3

100574 3-D-W33-1-O/P Okumura GenkiDepartment of Immunology, Faculty of medicine, University of

TsukubaThe role of soluble CD155 in tumor immune response and metastasis 7 3

100299 3-D-W33-2-O/P Ibuki HaradaDepartment of Immunology, Yokohama City University Graduate

School of Medicine, Yokohama, Japan

Soluble factors produced by BCR-ABL-positive leukemic cells may compromise antitumor

immunity in chronic myeloid leukemia 7 3

100404 3-D-W33-3-O/P Hirotake TsukamotoDepartment of Immunology, Graduate School of Medical Sciences,

Kumamoto University, Kumamoto, Japan

Combined blockade of IL-6 and PD-L1 signals breaks a mutual regulation of their

immunosuppressive effects on anti-tumor immunity 7 3

100462 3-D-W33-4-O/P Haruka WadaDivision of Immunobiology, Institute for Genetic Medicine, Hokkaido

UniversityTumor initiating cell in immunocompetent animal defined by immunological features 7 3

100055 3-D-W33-5-O/P Chie Kudo-SaitoDepartment of Immune Medicine, National Cancer Center Research

Institute, Tokyo, Japan

Targeting the pathogenic mesenchymal stromal/stem cells prevents immune

exhaustion 7 3

100634 3-D-W33-6-O/P Aya HirataDepartment of Immune Medicine, National Cancer Center Research

InstituteEffect of Imatinib mesylate to tumor immunosuppressive microenvironment 7 3

100114 3-D-W33-8-O/P Marija MojicDivision of Pathogenic Biochemistry Institute of Natural Medicine,

University of Toyama, Toyama, Japan

Tumor-specific CTL's reduced clonality and proliferation index, not the inhibitory immune

checkpoint expression, as hallmarks of B16 melanoma immune evasion 7 3

100575 3-D-W33-9-O/P Satoshi UehaDepartment of Molecular Preventive Medicine, Graduate School of


TCR sequencing reveals the generation and expansion of tumor-specific CD8+ T cell

clones after anti-CD4 antibody treatment in tumor-bearing mice 7 3

Toshihiko

Torigoe

Yoshihiro

HayakawaW33

Tumor

immunology-2

(Immunosuppre

ssion and

modulation in

tumor immunity)

Dec. 14

(Thu.), 201714:25 15:45 Room D

Yutaka

Kawakami

Hirokazu

MatsushitaW32

Tumor

immunology-1

(Tumor

antigens,

antigen

presenting cells,

anti-tumor T

cells)

Dec. 14

(Thu.), 201712:50 14:10 Room D

Tsuneyasu

Kaisho

Rikinari

HanayamaW31

Dendritic cells

and

Macrophages-3:

Inflammatory

Responses

Dec. 14

(Thu.), 201714:25 15:45 Room C

Tomohiko

Tamura

Masafumi

NakayamaW30

Dendritic cells

and

Macrophages-2:

Development

and Recognition

Dec. 14

(Thu.), 201712:50 14:10 Room C

9 / 12

100103 3-E-W34-1-O/P Sachiko HiroseToin Human Science and Technology Center, Department of

Biomedical Engineering, Toin University of Yokohama, Yokohama,

Japan

Independent effect of inhibitory IgG Fc receptor IIB

on B cells and monocytes on Yaa-induced murine

lupus7 3

100198 3-E-W34-2-O/P Hisashi NomuraDepartment of Dermatology, Keio University School of Medicine,

Tokyo, Japan

FcγRIIb plays an important role in maintaining clonal ignorance and prevents pemphigus

phenotype in pathogenic anti-desmoglein 3 antibody knock-in mice 7 3

100386 3-E-W34-3-O/P Hitomi Sakatani Nara Institute of Science and Technology, Nara, Japan Novel compounds that induce specifically class switching to IgA 7 3

100489 3-E-W34-4-O/P Saori FukaoResearch Institute for Biomedical Sciences, Tokyo University of

Science, Chiba, JapanRegulation of IgE production by an RNA binding protein 7 3

100315 3-E-W34-5-O/P Akihiko MutoDepartment of Biochemistry, Tohoku University Graduate School of

Medicine, Miyagi, JapanSingle-cell analysis of gene regulatory network in activated B cells 7 3

100613 3-E-W34-6-O/P Adachi TakahiroDepartment of Immunology, Medical Research Institute, Tokyo

Medical and Dental University, Tokyo, Japan

Intravital imaging of Ca2+ signals in lymphocytes of the Ca2+ biosensor

YC3.60 transgenic mice 7 3

100089 3-E-W34-7-O/P Mineto OtaThe Department of Allergy and Rheumatology, Graduate School of

Medicine, The University of Tokyo, Tokyo, JapanAbnormal B cell receptor repertoire maturation in SLE unveiled by RNA sequencing of immune cells 7 3

100043 3-E-W34-8-O/P Tsubasa OkanoDepartment of Pediatrics and Developmental Biology, Graduate

School of Medical and Dental Sciences, Tokyo Medical and Dental

University (TMDU), Tokyo, Japan

Maternal B cells, engrafted in patients with X-linked severe combined immunodeficiency (X-SCID),

could undergo class switch recombination without somatic hypermutation and cause IgG1

gammopathy.7 3

100426 3-E-W35-1-O/P Katsuya SatoDepartment of Molecular Pathobiochemistry, Gifu University School

of Medicine, Gifu, JapanAnalysis of cis-regulatory elements involved in the regulation of expression of Aicda 7 2

100126 3-E-W35-2-O/P Mayuko ShimodaLaboratory of Host Defense, Research Institute for Microbial

Diseases Osaka University, Suita, Osaka, JapanGANP maintains antibody structural integrity during somatic hypermutation 7 2

100610 3-E-W35-3-O/P Kei HaniudaResearch Institute for Biomedical Sciences, Tokyo University of

Science, Chiba, JapanGerminal center B cell development by glycolysis and mitochondrial metabolism 7 2

100585 3-E-W35-4-O/P Wataru IseImmunology Frontier Research Center, Osaka University, Osaka,

JapanThe heightened T-B interaction associates with plasma-prone germinal center B cells 7 2

100598 3-E-W35-5-O/P Atsuko KayabaDepartment of Experimental Immunology, Institute of Development,

Aging and Cancer, Tohoku University, Sendai, Japan

PIR-B suppresses IL-6 secretion from mesenchymal stem cells and regulates the immunoglobulin

production of plasma cells. 7 2

100527 3-E-W35-6-O/P Ari Itoh-NakadaiDepartment of Experimental Immunology, Institute of Development,

Aging and Cancer, Tohoku University, Tokyo, JapanSecretory leukocyte peptidase inhibitor (SLPI) is highly expressed in long-lived plasma cells 7 2

100636 3-E-W35-7-O/P Koji TokoyodaDeutsches Rheuma-Forschungszentrum Berlin (DRFZ), Berlin,

GermanySalmonella remotely suppresses long-lasting humoral immunity 7 2

100374 3-E-W35-8-O/P Katsuki UsamiInternational Education and Research Center for Food and

Agricultural Immunology, Graduate School of Agricultural Science,

Tohoku University, Miyagi, Japan

Important role of the immunological network between large intestine and mammary gland in

breastfeeding 7 2

100406 3-E-W35-9-O/P Hirohiko OnoNational Center of Neurology and Psychiatry National Institute of

Neuroscience, Department of Immunology, Tokyo, JapanDysregulated B cells in Myalgic encephalomyelitis/Chronic Fatigue Syndrome 7 2

100326 3-F-W36-1-O/P Akira NakajimaCenter for Innovation in Immunoregulative Technology and

Therapeutics, Graduate School of Medicine, Kyoto University

Mucus-associated functional factors in Bacteroidetes promotes inter-

phylum symbiosis and colonic homeostasis 7 3

100344 3-F-W36-3-O/P Eiji Miyauchi Laboratory for Intestinal Ecosystem, IMS, RIKEN, Yokohama, JapanMimicry peptides from gut commensals stimulate myelin-specific T cells and exacerbate experimental

autoimmune encephalomyelitis 7 3

100660 3-F-W36-5-O/P Takashi TanakaLaboratory for Inflammatory Regulation, REKEN Center for Integrative

Medical Sciences, Yokohama, Japan

Microbiota-dependent development of non-alcoholic steatohepatitis (NASH) in PDLIM2-

deficient mice. 7 3

100052 3-F-W36-9-O/P Masaaki HASHIGUCHIDepartment of Immunology, Dokkyo Medical University School of

Medicine, Mibu, Tochigi, Japan

Tumor necrosis factor superfamily member (TNFSF) 13, APRIL and TNFSF13B, BAFF downregulate

homeostatic immunoglobulin production in intestines 7 3

100243 3-F-W36-11-O/P Tadashi TakeuchiLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative

Medical SciencesGut microbial metabolite acetate modulates affinity of IgA to maintain intestinal homeostasis 7 3

100293 3-F-W36-14-O/P Mayuri TanakaLaboratory of Adjuvant Innovation, Center for Vaccine and Adjuvant

Research, National Institutes of Biomedical Innovation, Health and

Nutrition, Osaka, Japan

Essential role of CARD14 in murine experimental psoriasis 7 3

100601 3-F-W36-17-O/P Saeko NakajimaDepartment of Dermatology, Kyoto University Graduate School of

Medicine

Candida albicans skin colonization exacerbates the inflammation of murine psoriasis-like

dermatitis 7 3

100624 3-F-W36-18-O/P Gyohei EgawaDepartment of Dermatology, Kyoto University Graduate School of

Medicine, Kyoto, Japan

Revisiting the concept of CHS response; effector T cells infiltrates into the hapten-entry sites

and confer long-lasting local memory 7 3

Koji HaseGyohei

EgawaW36

Mucosal-Skin

Immunity-2

Dec. 14

(Thu.), 201712:50 14:10 Room F

Masaki Hikida Wataru IseW35

Germinal center

reaction and

plasma cells

Dec. 14

(Thu.), 201714:25 15:45 Room E

Yoshiteru

Sasaki

Reiko

ShinkuraW34

B cell

development

and function

Dec. 14

(Thu.), 201712:50 14:10 Room E

10 / 12

100323 3-F-W37-1-O/P Hiroe Tetsu Laboratory for innate Immune Systems, RIKEN, IMS, Japan Role of group 2 innate lymphoid cells in the skin 7 2

100486 3-F-W37-4-O/P Chieko IshifuneDepartment of Immunology and Parasitology, Institute of Biomedical

Sciences, Tokushima University Graduate School, Tokushima, Japan

Notch signal controls the number of

TCRαβ+CD8αα+ intraepithelial lymphocytes via

phospholipid asymmetry by maintaining fllipase ATP8a27 2

100175 3-F-W37-6-O/P Hideaki TakagiDivision of Immunology, Department of Infectious Diseases, Faculty

of Medicine, University of MiyazakiTolerogenesis of gastrointestinal plasmacytoid dendritic cells impacts the induction of oral tolerance 7 2

100253 3-F-W37-7-O/P Takashi KanayaLaboratory for Intestinal Ecosystem, RIKEN Center for Integrative

Medical Sciences, Yokohama, Kanagawa, Japan

IL-22 binding protein (IL-22BP) regulates the properties of follicle-associated epithelium (FAE) to

facilitate antigen uptake into Peyer’s patches 7 2

100639 3-F-W37-11-O/P Kamachi FumitakaDepartment of Applied Biological Science, Faculty of Science and

Technology, Tokyo University of Science, Chiba, JapanEffects of gut microbial metabolites of linoleic acid on cytokine profuction by immune cells 7 2

100388 3-F-W37-12-O/P Motoyoshi NagaiGraduate School of Pharmaceutical Science, Keio University, Tokyo,

Japan

Nutritional signals are essential for the regulation of cell dynamics and mucosal immune response in

GALT 7 2

100221 3-F-W37-15-O/P Hidehiko SuzukiLaboratory of Vaccine Materials and Laboratory of Gut Environmental

System, National Institutes of Biomedical Innovation, Health and

Nutrition (NIBIOHN)

Development of divalent food poisoning vaccine by augmented antigenicity of Clostridium

perfringens enterotoxin 7 2

100452 3-F-W37-17-O/P Hideki Asanuma National Institute of Infectious Diseases, Tokyo, JAPANEssential roles for protective SIgA Abs induced by nasal G9.1 combined influenza VLP

vaccine 7 2

100127 3-G-W38-1-O/P Shigeru IwataThe First Department of Internal Medicine, School of Medicine,

University of Occupational & Environmental Health, Japan,

Kitakyushu, Fukuoka, Japan

IFN-γ-T-bet mediated metabolic reprograming

in T　helper 1 cellsand its relevance to

pathogenesis of SLE7 4

100023 3-G-W38-2-O/P Maiko Okumura1st Department of Internal Medicine, Graduate School of Medicine

and Pharmaceutical Sciences (Medicine), University of Toyama

Production of Ro52/TRIM21 autoantibodies that react to PEP08 epitope in Ro52 clinically relate to the

morbidity and severity of interstitial lung disease in connective tissue diseases. 7 4

100156 3-G-W38-3-O/P Yusuke Takeshima1Department of Allergy and Rheumatology, Graduate School of

Medicine, the University of Tokyo, Tokyo, Japan

Comprehensive analysis of genome and transcriptome analysis of immune cell subsets in peripheral

blood mononuclear cells (PBMCs) revealed mitochondria contribution in B cells to systemic lupus

erythematosus.7 4

100331 3-G-W38-4-O/P Natsumoto BunkiDepartment of Allergy and Rheumatology, Graduate School of

Medicine, The University of Tokyo, Japan

Pathophysiological analysis of systemic lupus erythematosus (SLE) using patient-derived induced

pluripotent stem cells 7 4

100307 3-G-W38-6-O/P Yukiko IwasakiDepartment of Allergy and Rheumatology, Graduate School of

Medicine, The University of Tokyo, Japan

Plasma metabolomic analysis combined with transcriptome data has potential for stratification of SLE

patients 7 4

100552 3-G-W38-7-O/P Yuki SasagawaLaboratory of Immunochemistry, WPI Immunology Frontier Reseach

Center, Osaka University, Osaka, Japan

Antiphospholipid antibody recognizes β2GPI complexed with HLA class II molecules via its

domain V 7 4

100573 3-G-W38-8-O/P Satoko MorikamiDepartment of Obstetrics and Gynecology, Kobe University Graduate

School of Medicine, Hyogo, Japan

Prothrombin complexed with HLA class II molecules is an autoantibody target in antiphospholipid

syndrome 7 4

100222 3-G-W39-4-O/P Haruka TsuchiyaDepartment of Allergy and Rheumatology, The University of Tokyo,

Tokyo, Japan

Identification EP300 as a Novel Therapeutic Target for Rheumatoid Arthritis by the Comprehensive

Analysis of Fibroblast-like Synoviocytes 7 4

100255 3-G-W39-5-O/P Shinsuke YasudaDepartment of Rheumatology, Endocrinology and Nephrology, Faculty

of Medicine and Graduate School of Medicine, Hokkaido University,

Sapporo, Japan

RasGRP-Ras-MAPK activation in fibroblast-like synoviocytes from patients

with rheumatoid arthritis and inhibition of this pathway by Ras translocation 7 4

100036 3-G-W39-7-O/P Harumi ShiraiDepartment of Allergy and Rheumatology, Graduate School of


Investigation of pathogenesis of Adult onset Still’s disease through lymphocyte subsets

analysis in peripheral blood followed by RNA-sequencing 7 4

100084 3-G-W39-8-O/P Noriko AraseDepartment of Immunochemistry, Research Institute for Microbial

Diseases, Osaka UniversityRecognition of SS-A/IgG/HLA-DR complex by autoantibodies in Sjogren’s syndrome 7 4

100132 3-G-W39-9-O/P Yoshinobu KoyamaCenter for Autoimmune Diseases, Division of Rheumatology, Japan

Red Cross Okayama Hospital,Okayama, Japan

Exercise-induced pulmonary hypertension at early stage of systemic sclerosis: changes in gene

expression of peripheral blood cells 7 4

100480 3-G-W39-10-O/P Yoshimichi OkayamaAllergy and Immunology Research Project Team, Center for

Institutional Research and Medical Education, Nihon University

School of Medicine

Autoantibodies (AAbs) against the FcεRI α-chain and IgE in patients with chronic

spontaneous urticaria (CSU) induced statistically higher ability of FcεRI aggregation compared

with non-atopic control (NC) subjects7 4

100314 3-G-W39-11-O/P Sugimori YusukeDepartment of Allergy and Rheumatology, Graduate School of


Comprehensive Flow Cytometric Analysis of Immune Cell Subsets in PBMCs from Idiopathic

Inflammatory Myopathy Patients 7 4

100363 3-H-W40-1-O/P Jing WangInstitute of Enzyme Research, Tokushima University, Tokushima,

JapanTracking the fate of neutrophils in sterile injury using photoactivation and intravital imaging 7 3

100370 3-H-W40-14-O/P Wakabayashi Seiichiro Dermatology, Chiba University, Chiba, JapanHomeostasis of peripheral macrophages are controlled by mast cells via newly identified c-

Kit+CD11b+ tissue-resident macrophage progenitor cells 7 3

100434 3-H-W40-15-O/P Yuta KogureDivision of Mucosal Immunology, Department of Microbiology and


Tokyo, Tokyo, Japan

Mesenchymal-mediated skin-specific regulatory system for the control of tissue resident mast cells 7 3

100604 3-H-W40-20-O/P Shota ToyoshimaAllergy and Immunology Research Project Team, Center for

Institutional Research and Medical Education, Nihon University


Comparison of microRNA in human mast cell-derived exosomes in innate and acquired immunity 7 3

100616 3-H-W40-21-O/P Jun-ichi KashiwakuraDepartment of Immunology, Graduate School of Pharmaceutical

Sciences, Hokkaido University, Hokkaido, JapanSTAP-2 is an adopter molecule to positively regulate basophil activation 7 3

100456 3-H-W40-22-O/P Tomoyuki BandoOno pharmaceutical co., ltd. Exploratory Research Laboratories,

Osaka, JAPAN

Differential usage of COX-1 and COX-2 in prostaglandin production by mast cells and

basophils 7 3

100488 3-H-W40-24-O/P Takuya OHTADepartment of Immune Regulation, Tokyo Medical and Dental

University Graduate School, Tokyo, Japan

Skin-resident memory CD4+ T cells play an essential role in acquired tick resistance

through IL-3-mediated basophil recruitment 7 3

100665 3-H-W40-27-O/P Kensuke MiyakeDepartment of Immune Regulation, Graduate School of Medical and

Dental Sciences, Tokyo Medical and Dental University (TMDU),

Tokyo, Japan

Basophils exert antigen presentation via trogocytosis-mediated acquisition of peptide-MHC class II

complexes from dendritic cells (DCs) 7 3

Atsuhito

Nakao

Yosuke

KurashimaW40

Granulocyte &

Mast cells

Dec. 14

(Thu.), 201712:50 14:10 Room H

Kimito

Kawahata

Shingo

NakayamadaW39

Systemic

autoimmune

disease (3)

Dec. 14

(Thu.), 201714:25 15:45 Room G

Yoshiya

Tanaka

Masayuki

NishideW38

Systemic

autoimmune

disease (2)

Dec. 14

(Thu.), 201712:50 14:10 Room G

Eiji UmemotoJun

KunisawaW37

Mucosal-Skin

Immunity-3

Dec. 14

(Thu.), 201714:25 15:45 Room F

11 / 12

100433 3-H-W41-1-O/P Takumi ItohDepartment of Therapy Development and Innovation for Immune

disorders and Cancers, Graduate School of Medicine, Juntendo


IL-26 facilitates angiogenesis and skin inflammation via inducing FGF2 production in a murine model

of imiquimod-induced psoriasis 7 3

100482 3-H-W41-4-O/P Taro WatabeDepartment of gastroenterology, Tokyo Medical and Dental University,

Tokyo, JapanAnalysis of ileocecal immune response in an experimental colitis model using intra-vital imaging 7 3

100385 3-H-W41-9-O/P Kota NishihamaMie University Graduated School of Medicine, Diabetes, Metabolism

and Endocrinology, Tsu, JapanAnti-diabetic effect of matrix metalloproteinase-2 and its correlation with protein S in diabetes 7 3

100415 3-H-W41-11-O/P Atsuro TakeshitaDiabetes, Metabolism and Endocrinology, Mie University Graduate

School of Medicine, Tsu, JapanProtein S reduces the progression of diabetic nephropathy in mice 7 3

100330 3-H-W41-13-O/P Yosuke KurashimaDivision of Mucosal Immunology, Department of Microbiology and


Tokyo, Tokyo, Japan

Mesenchymal-myeloid cell interactions in renal microenvironment for pathological fibrogenic

machinery in kidney fibrosis 7 3

100638 3-H-W41-14-O/P Naoto SasakiDepartment of Medical Pharmaceutics, Kobe Pharmaceutical

University, Kobe, Japan

Ultraviolet B exposure prevents atherosclerotic cardiovascular disease by regulating

immunoinflammatory responses 7 3

100492 3-H-W41-15-O/P Akira TaruyaDepartment of Cardiovascular Medicine, Wakayama Medical

University, Wakayama, JapanDecline of lysyl oxidase protein causes acute aortic dissection in Spi-B knockout mice 7 3

100437 3-H-W41-16-O/P Tomonori KaifuDepartment of Immunology, Tohoku Medical and Pharmaceutical

UniversityDCIR negatively regulates osteoclastogenesis by binding to a novel endogenous ligand 7 3

100609 3-I-W42-4-O/P Ryunosuke MuroGraduate School of Medicine and Faculty of Medicine, The

University of Tokyo, Japan

Control of proinflammatory γδT cell development by linage-specific TCR signaling

pathway 7 3

100015 3-I-W42-5-O/P Honglian TongDivision of Molecular and Cellular Immunoscience, Department of

Biomolecular Sciences, Faculty of Medicine, Saga University, Saga,

Japan

Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-

stimulated T cells 7 3

100391 3-I-W42-6-O/P Takayuki ImanishiRIKEN Center for Integrative Medical Sciences (IMS) Laboratory for

Cell Signaling, Yokohama, JapanTCR-signals control STING-mediated type 1 IFN responses in T cells 7 3

100178 3-I-W42-9-O/P Eun Jeong Park Mie University Graduate School of Medicine, Mie, Japan β7 integrin-mediated homing of exosomes to the gut 7 3

100594 3-I-W42-10-O/P Yuji KamiokaDepartment of Molecular Genetics, Institute of Biomedical Science,

Kansai Medical University, Osaka, JapanRoles of Rap1 and Kindlin-3 in lymphocyte homing to peripheral lymph nodes 7 3

100417 3-I-W42-11-O/P Tsuyoshi SatoDepartment of Biosciences, School of Science, Kitasato University,

kanagawa, JapanT cell specific Rap1-deficient mice develop spontaneous colitis 7 3

100461 3-I-W42-12-O/P Naoyuki Kondo Kansai medical university, Hirakata, Osaka, Japan NDR1 acts as a molecular hub for the organization of immunological synapse 7 3

100478 3-I-W42-14-O/P Akiko Hashimoto-Tane RIKEN Center for Integrative Medical Science, Yokohama, Japan Molecular assembly and function of PTPN22 in T cell receptor signaling 7 3

100187 3-I-W43-1-O/P Jisu MaDepartment of Immunoparasitology, Research Institute for Microbial

Diseases, Osaka University, Osaka, Japan

PLCβ plays an important role in CD8 T cell-mediated host defense against

Toxoplasma gondii 7 3

100059 3-I-W43-5-O/P Akihiro ShimbaInstitute for Frontier Life and Medical Sciences, Kyoto University,

Kyoto, Japan

Glucocorticoids drive diurnal changes in distibution and response of T cells via IL-7 receptor

expression 7 3

100262 3-I-W43-8-O/P Mohammad A SAYEMDivision of Cellular Signaling, Advanced Institute of Medical

Research, Keio University School of Medicine, Tokyo, Japan

IL-8 has a negative role on tumor infiltrating CD8+ T cells in various

cancers 7 3

100563 3-I-W43-11-O/P Akio OhtaDepartment of Molecular Medicine, Foundation for Biomedical

Research and Innovation, Kobe, JapanTransient hypoxia persistently inhibits T cell activation 7 3

100022 3-I-W43-13-O/P Junpei SuzukiDepartment of Hematology, Clinical Immunology and Infectious

Diseases, Ehime University Graduate School of Medicine, Ehime,

Japan

The tumor suppressor menin epigenetically regulates CD8 T cell senescence via the

modulation of glutamine metabolism 7 3

100582 3-I-W43-14-O/P Hisako AkatsukaDepartment of Host Defense Mechanism, Tokai University School. of

Medicine, Kanagawa Japan

AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through ATG7-independent

pathway 7 3

100140 3-I-W43-15-O/P Michio MiyajimaLaboratory for Mucosal Immunity, Center for Integrative Medical

Sciences, RIKEN Yokohama Institute, Yokohama, Japan

Systemic metabolic shift induced by PD-1 deficiency perturbs brain monoamines and emotional

behaviour 7 3

100414 3-I-W43-17-O/P Harumichi IahigameLaboratory for Tissue Dynamics, RIKEN Center for Integrative

Medical Sciences, Kanagawa, Japan

Developmental plasticity of KLRG1+ effector CD8+ T cells

promotes protective immunity 7 3

Harumi SuzukiEi

WakamatsuW43

T cell-3 : T cell

function

Dec. 14

(Thu.), 201714:25 15:45 Room I

Satoshi

Matsuda

Tadashi

YokosukaW42

T cell-2 : T cell

signaling

Dec. 14

(Thu.), 201712:50 14:10 Room I

Keishi FujioMotomu

HashimotoW41

Tissue-specific

immune

diseases III

Dec. 14

(Thu.), 201714:25 15:45 Room H

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the 46th annual meeting of the japanese society for...

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