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Scientific Program1082nd Conference

July 31-August 02, 2017 Milan, Italy

7th Global Experts Meeting on

Neuropharmacology

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RegistrationsDay 1 July 31, 2017

Keynote ForumIntroductionTitle: Blood-brain barrier in Alzheimer’s disease induced brain pathology and neuroprotection by nanodelivery of cerebrolysinHari Shanker Sharma, Uppsala University, SwedenTitle: Co-ultramicronized palmitoylethanolamide/luteolin facilitates oligodendrocyte precursor cell development and improves outcome in experimental autoimmune encephalomyelitisStephen D Skaper, University of Padua, ItalyTitle: Mitochondrial lesions as an earlier hallmark for liver and brain neuronal damage during the chronic ethanol self-administration in Cynomolgus monkeys: New challenge for treatment strategy Gjumrakch Aliev, GALLY International Biomedical Research Institute Inc., USA

Networking and Refreshments BreakTitle: The impact of dementia on migrant communities: A complex challenge in a globalized worldDavid Truswell, Somefreshthinking Consultancy, UKSessions: Neuroimmunology and Neuroinflammation | Neurochemical Transmission | Alzheimer’s Disease and Dementia | Parkinson’s DiseaseSession Chair: Harish C Pant, National Institutes of Health, USASession Chair: Aruna Sharma, Uppsala University, Sweden

Session IntroductionTitle: Oral treatment with sphingosine-1-phosphate receptors modulator prevents Parkinson symptoms concomitantly to reduced brain inflammation in MPTP mouse modelsMichel CYR, University of Trois-Rivieres, CanadaTitle: The impact of brain lesions on basic emotions and emotion regulation in stroke survivorsMarina Farinelli, Ospedale Privato Villa Bellombra- Consorzio Colibri'- Bologna, Italy Title: ApoE4- targeted therapeutics for ADVarghese John, University of California, USA Title: Intravenous immunoglobulins for children refractory epilepsyAlireza Rezayi, Shahid Beheshti University of Medical Sciences, Iran

Lunch BreakSpecial Session

Title: Translational approach to Neurodegenerative diseases: A small peptide derived from neuronal cell cycle kinase (Cdk5) prevents neurodegeneration Harish C Pant, National Institutes of Health, USASession Chair: Gjumrakch Aliev, GALLY International Biomedical Research Institute Inc., USASession Chair: David Truswell, Somefreshthinking Ltd., UK

Session Introduction

Opening Ceremonyconferenceseries.com

Spiga+S. Andrea

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Title: Thalamocortical circuit in sleep control: The thalamic mGluR1-PLCβ4 pathway is critical in sleep architectureEunji Cheong, Yonsei University, South KoreaTitle: Inhibition of signal transducer and activator of transcription 3 (STAT3) reduces neonatal hypoxic-ischemic brain damageMariya Hristova, University College London, UKTitle: Can tau pathobiology be phenocopied in a cellular expression model?Joel B Schachter, Merck Research Laboratories, USATitle: Nanodelivery of cerebrolysin induces neuroprotection in Parkinson’s diseaseAruna Sharma, Uppsala University, Sweden

Networking and Refreshments BreakTitle: Psychobiotic PS128 rescued motor deficits in MPTP-induced mice modelYing-Chieh Tsai, National Yang-Ming University, TaiwanTitle: Therapeutic strategies for the Parkinson's patient with Alzheimer's changes: The benefits of art, structure and nutritionElizabeth K Barber, Barber Innovations LLC, USA

Panel DiscussionDay 2 August 01, 2017

Spiga+S. AndreaKeynote Forum

IntroductionTitle: Novel paradigm of the development of preclinical diagnosis of Parkinson’s disease Michael V Ugrumov, Institute of Developmental Biology RAS, RussiaTitle: Initial studies on neuroimmune biologyIstvan Berczi, University of Manitoba, CanadaTitle: Molecular mechanism and intervention studies of regenerative mossy fiber sprouting in hippocampus following developmental seizures Ni Hong, Soochow University, China

Networking & Refreshments BreakTitle: PARP1 dependent long-term memory acquisitionM Cohen-Armon, Tel-Aviv University, Israel

Special SessionTitle: The intuitive rational-choice theory of madness: Schizophrenia, criminal insanity & neuroses the fallen empires of psychoanalysis, medical models and drug companiesYacov Rofé, Bar-Ilan University, Israel

Poster PresentationsPoster Judge: Hari Shanker Sharma, Uppsala University, SwedenPoster Judge: Joel B Schachter, Merck Research Laboratories, USA

NPC-001Title: Can we target amino acid metabolism to affect brain tumor growth?Eduard H Panosyan, LABioMed/Harbor-UCLA, USA

NPC-002Title: In vitro effects of newly derivatives of caffeine-8-a-methyl thioglycolic acid on neuroblastoma cell line SHSY5YAlexandra Kasabova, Medical University-Sofia, Bulgaria

NPC-003Title: In vitro effects of new caffeine derivatives on isolated rat synaptosomes

Borislav Angelov, Medical University-Sofia, Bulgaria

NPC-004Title: In vitro study of newly synthesized derivatives of caffeine-thioglycolic acid – effects on contractile activity of small brain vesselsMartin Vasilev, Medical University-Sofia, Bulgaria

NPC-005Title: Investigating the mechanism of action of novel smoothened antagonists discovered by in silico screening of the homodimer interface P Banerjee, Neuroscience Paris-Saclay Institute, France

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NPC-006

Title: Postural stability of patients with distal symmetric diabetic polyneuropathy after combined pharmacotherapy with alpha-lipoic acid and benfotiamin, pyridoxine and cyancobalamine Dorina Petrova, National Transport Hospital “Tzar Boris III”, Bulgaria

NPC-007Title: Studying the effectiveness of venlafaxine in mice model of post-traumatic stress disorderNatalia Malikowska, Jagiellonian University Medical College, Poland

NPC-011Title: Jurisdictional consequences in some brain conditionLuisetto Mauro, European specialist in lab medicine, Italy

Lunch BreakSessions: Clinical Neuropharmacology | Psychopharmacology | Behavioral and Addiction Neuropharmacology | NeurotechnologySession Chair: Hari Shanker Sharma, Uppsala University, SwedenSession Chair: Stephen D Skaper, University of Padua, Italy

Session IntroductionTitle: Deep brain stimulation for uncontrollable aggressive behaviour: The benefit beyond our expectationsOscar Bernal-Pacheco, Instituto Roosevelt, ColombiaTitle: Prolonged inhibition of semaphoring-3A pathway via biodegradable implant towards a better therapy for visual sensory impairmentsArieh S Solomon, Tel Aviv University, IsraelTitle: The use of mTOR inhibitor for the treatment of refractory seizures in an infant with hemimegencephalyAnita N Datta, University of British Columbia, CanadaTitle: Delayed cytokine effects of 4 days of intravenous G-CSF infusion for mobilization of peripheral blood stem cells: Possible role for neuroregeneration Young-Ho Lee, Hanyang University College of Medicine, South KoreaTitle: The effects of combination treatment with PME-88 and riluzole on the ALS mouse modelHyo Joon Kim, Presbyterian Medical Center, South KoreaTitle: Exploring the cultural-specific challenges and opportunities of the autism spectrum disorders populations in China and Hong KongKay Chang, University of Macau, China

Networking & Refreshments BreakSession Chair: Ni Hong, Soochow University, ChinaSession Chair: Stephen D Skaper, University of Padua, Italy

Session IntroductionTitle: Peroxynitrite could be a critical therapeutic target for preventing hemorrhagic transformation and poor outcome in ischemia-reperfused rat brains with delayed thrombolysisJiangang Shen, The University of Hong Kong, ChinaTitle: Emotional empathy and cognitive styles in psychodynamic group therapy: UAE experienceHala Fakhiry, Cairo University, Egypt

Young Reseacher’s ForumTitle: Activated M2 phenotype microglia induce differentiation and polarization of monocyte and chemo-attraction in in vitro systemYeonseung Han, Yonsei University, South KoreaTitle: The antiangiogenic activities of Synanthedon tipuliformis sexual pheromone on chorioallantoic membraneZeynab-Sadat Payambarpour, Shahed University, Iran

Day 3 August 02, 2017Spiga+S. Andrea

Sessions: Neural Stem Cell | Neuroethics | Molecular Neuropharmacology | Future Aspects of Neuropharmacology | Case Study Reports Session Chair: Jan Ulfberg, Capio Sleep Center, SwedenSession Chair: Hua P Su, MSD Research Labs, USA

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Session IntroductionTitle: Characterization of non-active site, TrkA selective kinase inhibitors and implications on obtaining kinase selectivityHua P Su, MSD Research Labs, USATitle: Treatment with selenium in restless legs syndromeJan Ulfberg, Capio Sleep Center, SwedenTitle: Combination brexpiprazole and aripiprazole long-acting injectable therapy for treatment-resistant schizophreniaMathew Nguyen, Meridian Behavioral Healthcare, USATitle: New sole presentation for childhood epilepsyMaha Nada, Ain Shams University, EgyptTitle: Tanakan (EGb 761®): New therapeutic possibilities in neurorehabilitationSaule T Turuspekova, KazNMU, Kazakhstan

Networking & Refreshments BreakTitle: The molecular basis of the neurotrophic action of vitamin B12 (Cobalamin)Giuseppe Scalabrino, University of Milan, Italy

Young Reseacher’s ForumTitle: Studying the effectiveness of venlafaxine in mice model of posttraumatic stress disorderNatalia Malikowska, Jagiellonian University Medical College, PolandTitle: Developmental and adult expression of the GPR88: Establishment of its interaction with nuclear partner proteins in the cerebral cortexFlorian Rebeillard, Université Paris Descartes, France

Lunch Break

Panel DiscussionAwards & Closing Ceremony