14th MEET THE PROFESSOR

Advanced InternationalBreast Cancer CoursePADUA, SEPTEMBER 20th-22nd, 2018

DirectorsPier Franco Conte, Gabriel N. Hortobagyi

SECTION OF ONCOLOGY

Breast cancer represents the front runner in cancer research in many aspects. First, this is a common, chronic and lethal disease where medical interventions are successfully inducing a continuous decline in mortality in spite of increasing incidence. Second, biology drives  the entire diagnostic-therapeutic work up of these patients. For these reasons, nowadays, a breast multidisciplinary team should also include pathologists, molecular biologists, oncogeneticists besides the “classic” clinical specialties. Finally, many highly effective interventions are available for each step of the diagnostic and therapeutic work-up of these patients. The increased complexity of the disease, the availability of multiple effective choices and the high expectations of our patients are raising the bar of clinical excellence in this field.

With this goal in mind, the Programme of this international Conference includes lectures on molecular characterization, updated treatments of early and advanced disease, management of difficult cases and hereditary syndromes.

Clinical case discussions and debates are planned to allow a continuous and fruitful exchange of experiences and opinions between speakers and participants.

This 14th Breast Cancer Conference includes a highly qualified international faculty, but will maintain its characteristics of a friendly forum where opinion leaders and attendees will exchange experiences and share the most exiting advances.

In order to reward scientific excellence and to foster international cooperation, the International Scientific Committee of the 14th AIBCC will award the 8th International Prize for Breast Cancer Research to a scientist who has published a breakthrough paper in the previous year. For the first time, we also welcome the presentation of posters from the participants and the best poster will be awarded during the Award Cerimomy.

We welcome medical oncologists, pathologists, breast surgeons, radiation oncologists and basic scientists to listen to breast cancer leaders and to exchange experiences in a friendly atmosphere.

Aims

Gynaecologists and obstetrics, medical oncologists, pathologists, radiologists, radiation oncologists, surgeons. Biologists and nurses. Pharmacists.It won’t be possible to give credits to physicians specialized in different fields.

Addressed to

ProgrammeThursday, September 20th

8.30 Registration

9.15 Introduction to the Conference Pier Franco Conte, Gabriel N. Hortobagyi

SESSION I - EVOLUTION IN BREAST CANCER PREVENTION Chairmen: Francesca Caumo, Stefania Zovato

9.30 Population screening vs risk-adapted surveillance Sylvia Heywang – Kobrunner

9.50 Pharmacological prevention: how and whom? Elefterios Mamounas

10.10 A look into the future: multigene panels Gabriel N. Hortobagyi

10.30 Q&A

10.45 Coffee break

SESSION II - LOCOREGIONAL TREATMENT Chairmen: Jacek Jassem, Gabriel N. Hortobagyi

11.15 Evolution in surgical management of the axilla Viviana E. Galimberti

11.45 Do margins still matter for in situ and invasive lesions? Elefterios Mamounas

12.15 Radiation therapy: what is the real target to aim at Philip Poortmans

12.45 Q&A

13.00 Lunch

14.00 Multidisciplinary Tumor Board 1 – Locoregional treatment Chairman: Jacek Jassem

Panelists: Maia Dzhugashvili, Hesham Elghazaly, Viviana E. Galimberti, Philip Poortmans

Case 1: Locoregional relapse (questions: locoregional treatment with or without radiosensitisers e.g drugs, hyperthermia, EF? “Adjuvant” systemic treatment?) – Laura Martella

Case 2: Breast cancer in a patient previously treated with RT for Hodgkin disease (questions: locoregional treatment? contralateral mastectomy?) – Tania Saibene

Case 3: Healthy patient with familial history asking for risk-reducing mastectomy – Silvia Michieletto

Concluding comments – Jacek Jassem

SESSION III – SUPPORTIVE AND COMPLEMENTARY THERAPIES Chairmen: Pier Franco Conte, Stefania Migliuolo

15.00 Diet: myths and facts Mariateresa Nardi

15.20 Complementary therapies Claudia Bozza

15.40 Scalp cooling Laura Marchioro

16.00 Q&A

16.20 Coffee break

SESSION IV – LONG TERM CONSEQUENCES OF SYSTEMIC TREATMENTS Chairmen: Hesham Elghazaly, Valentina Guarneri

16.40 Gynecologic Marco Gambacciani

17.00 Cardiovascular and metabolic Giuseppe Curigliano

17.20 Bone health Ingo Diel

17.40 Q&A

18.00 Adjourn

Friday, September 21st

8.00 Poster display

SESSION V – PATHOLOGY, GENOMICS & MOLECULAR BIOLOGY Chairman: Enrico Orvieto

9.00 HER2 testing guidelines: new ASCO/CAP 2018 Giuseppe Viale

9.20 Molecular stratification of HER2+ and TNBC Aleix Prat

9.40 Lobular breast cancer: a separate entity? Caterina Marchiò

10.00 Q&A

10.20 Coffee Break

SESSION VI – NEW PATHWAYS AND NEW DRUGS Chairmen: Sybille Loibl, Aleix Prat

10.50 Insights in resistance to CDK4/6 inhibitors Stephen Johnston

11.10 Targeting the immune system: hopes and hypes Peter Schmid

11.30 Combining radiotherapy and immunotherapy Emanuela Romano

11.50 PARPi and other promising agents Gabriel N. Hortobagyi

12.10 Q&A

12.30 Lunch

SESSION VII – SYSTEMIC TREATMENTS FOR EARLY BREAST CANCER Chairmen: Stephen Johnston, Gabriel N. Hortobagyi

14.00 Extended adjuvant endocrine therapy: why? for whom? with what? Michael Gnant

14.30 Risk adapted adjuvant treatment for HER2+ disease Pier Franco Conte

15.00 Most promising ongoing trials in early disease Hope Rugo

15.30 Q&A

16.00 Multidisciplinary Tumor Board 2 – Early breast cancer: challenging cases for pathologists and clinicians

Chairman: Giuseppe Viale Panelists: Giulia Valeria Bianchi, Maria Vittoria Dieci, Miguel Martin,

Hope Rugo

Case 1: Rare histologies (pleomorphic lobular carcinoma, low aggressive triple negative histologies, micropapillary) – Vassilena Tsvetkova

Case 2: HER2+ (de-escalated treatments for HER2+ disease) Giulia Tasca

Case 3: Management of non pCR after neoadjuvant chemotherapy Carlo Alberto Giorgi

Concluding comments - Maria Vittoria Dieci

17.00 Adjourn

17.30 Ceremony for the presentation of the University of Padua Award for Advances in Breast Cancer 2018 and best poster award

17.45 Lecture of the Awardee

18.15 Cocktail

19.30 Adjourn

The Ceremony and the cocktail will take place in Palazzo Bo, Via VIII Febbraio 2, Padua

Saturday, September 22nd

SESSION VIII – Advanced Breast Cancer Chairmen: Pier Franco Conte, Stephen Johnston

9.00 New therapeutic algorithms HR+ disease - Sibylle Loibl HER2+ disease - Valentina Guarneri TN disease - Miguel Martin

10.30 Q&A

10.40 Coffee break

11.00 Do elderly patients require special management? Matti Aapro

11.20 Multidisciplinary Tumor Board 3 – Management of Advanced Breast Cancer

Chairman: Sandra Swain Panelists: Giulia Valeria Bianchi, Jacek Jassem, Philip Poortmans,

Hope Rugo

Case 1: Bone disease – Zora Baretta

Case 2: Brain mets – Gaia Griguolo

Case 3: Fulminat visceral disease – Luisa Carbognin

Case 4: Oligometastatic disease – Giacomo Pelizzari

Concluding comments – Sandra Swain

12.45 Adjourn and final evaluation questionnaire

Scientific CommitteeHesham ElghazalyDepartment of Clinical Oncology and nuclear medicineUniversity of AinshamsCairo (EG)

Valentina GuarneriDivision of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and GastroenterologyUniversity of Padua (I)

Jacek JassemDepartment of Oncology and RadiotherapyMedical University of Gdansk (PL)

Stephen JohnstonNIHR Biomedical Research Centre for CancerRoyal Marsden NHS Foundation Trust & Institute of Cancer ResearchLondon (UK)

Sibylle LoiblGerman Breast GroupDepartment of Medicine and ResearchUniversity of Frankfurt (D)

Miguel Martin Medical Oncology Service Hospital Universitario Gregorio Marañon Madrid (E)

Stefania MigliuoloEuropa Donna ItaliaMilan (I)

Fedro Alessandro PeccatoriDepartment of Medical OncologyEuropean Institute of Oncology (IEO)Milan (I)

Philip PoortmansPresident of ECCODepartment of Radiation OncologyInstitut CurieParis (F)

Aleix PratMedical Oncology DepartmentHospital ClinicBarcellona (E)

DirectorsPier Franco ConteDivision of Medical Oncology 2Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and GastroenterologyUniversity of Padua (I)

Gabriel N. HortobagyiDepartment of Breast Medical OncologyThe University of Texas MD Anderson Cancer CenterHouston (USA)

Speakers & Chairmen Matti S. Aapro Multidisciplinary Oncology Institute Clinique De Genolier Genolier (CH)

Zora Baretta Medical Oncology Unit AULS 8 Berica Distretto Ovest Arzignano (I)

Giulia Valeria Bianchi Medical Oncology Unit 1 IRCCS Istituto Nazionale Tumori Milan (I)

Claudia Bozza Department of Oncology ASUIUD Udine

Luisa Carbognin Medical Oncology Unit G.B. Rossi Hospital Verona (I)

Francesca Caumo Radiology Unit Istituto Oncologico Veneto IRCCS University of Padua (I)

Giuseppe Curigliano Department of Oncology European Institute of Oncology University of Milan (I)

Maria Vittoria Dieci Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Ingo Diel Gynaecology Unit Praxisklinik am Rosengarten Mannheim (D)

Maia Dzhugashvili Department of Radiation Oncology Instituto Madrileño de Oncología (Grupo IMO) Murcia (E)

Viviana E. Galimberti Unit of Molecular Senology European Institute of Oncology Milan (I)

Marco Gambacciani Obstetrics & Gynecology Unit S. Chiara Hospital Pisa (I)

Carlo Alberto Giorgi Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Michael Gnant Department of Surgery Medical University Wien (A)

Gaia Griguolo Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Sylvia H. Heywang-Köbrunner Head of Breast Diagnostics Munchen (D)

Eleuterios Mamounas MD Anderson Cancer Center Orlando Comprehensive Breast Program Orlando (F)

Caterina Marchiò Pathology Unit Candiolo Cancer Institute IRCCS Candiolo (I)

Laura Marchioro Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Laura Martella Medical Oncology “S. Anna” Hospital Cona, Ferrara (I)

Silvia Michieletto Breast Surgery Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Mariateresa Nardi Clinical nutrition and dietetics Istituto Oncologico Veneto Padova (I)

Enrico Orvieto General Pathology and Cytopatology Unit Department of Medicine-DIMED University of Padua (I)

Giacomo Pelizzari Medical Oncology Oncology Center Aviano (I)

Emanuela Romano Cancer Immunotherapy Center Institut Curie Paris (F)

Hope Rugo UCSF Carol Franc Buck Breast Care Center Breast Oncology Clinical Trials Program San Francisco (USA)

Tania Saibene Breast Surgery Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Peter Schmid Centre for Experimental Cancer Medicine Bart Cancer Institute Queen Mary University London (UK)

Sandra Swain M. Research Development Georgetown University Medical Center Washington (USA)

Giulia Tasca Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

VassilenaTsvetkova Division of Medical Oncology 2 Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology University of Padua (I)

Giuseppe Viale Department of Pathology European Institute of Oncology University of Milan (I)

Stefania Zovato Familial Cancer Clinic (Unità tumori ereditari) Istituto Oncologico Veneto IRCCS Department of Surgery, Oncology and Gastroenterology Padova

Award, Poster Session & FellowshipsUNIVERSITY OF PADUA AWARD FOR ADVANCES IN BREAST CANCER 2018

The Scientific Committee will select young researchers (< 40 years from any country) who have published in an international peer-reviewed journal, as the principal author, a manuscript reporting important clinical or biological advances in breast cancer. Prof. Conte and Prof. Hortobagyi will select the final winner which will be invited to present his/her study during the annual Conference.

POSTER SESSION

Participants can send one or more abstracts.

The form (available on the web site: https://meettheprofessor.accmed.org) should be filled out by following specific guidelines:• Use the capitol letter for the title• Indicate each author’s affiliation (that should include institution, department

and town)• Underline the designated presenting author’s name.• Use font Times New Roman 10, single line spacing.Abstracts will be selected by the Scientific Committee and will be shown during the poster session on September 22nd from 8 am. Poster size: 70 (wide) x 100 (high).

People sending the selected abstracts will have free registration, dinners and accommodation as well as a reimbursement of travel expenses (max of travel reimbursement € 200,00 for Italian participants and € 300,00 for European and worldwide participants). Abstracts should be sent within July 1st. A confirmation will be sent by email within July 20th.

FELLOWSHIPS

Some fellowship (for under 40) will be awarded which will include registration and 3 Hotel nights. Those interested should send the registration form together with a short CV and a motivation letter within July 1st. The organizing secretariat will confirm the award of the fellowship within July 20th and it will proceed with the organization of logistics.

Un’azione sostenibile a favore della formazioneIscrizione gratuita per i medici UNDER 35 fino a esaurimento posti

CME Based on Italian regulations, Accademia Nazionale di Medicina (provider n. 31) will assign to the activity CME (31-228175): 11,2 CME points.

The credit certification is subject to:• Professions/specializations should correspond to those which have been

accredited for CME;• 90% attendance to the meeting;• Completion of the meeting evaluation form;• Completion of the final questionnarie (at least 75% of correct answers).

We would like to remind you to participants that only 1/3 of CME credits acquired during the years 2017/2019 can come from a sponsorship.

Official LanguageThe official language of the Meeting is English. No simultaneous translation will be provided.

Free admission is available for 3 people “under 35”. Registration forms will be accepted on a first-come, first-served basis until spaces will be full. The Organization Secretariat will confirm the registration by email.

Under 35

The registration fee are:- € 250,00 - € 150,00 for graduate students - € 150,00 for nursesThey include the conference bag and all coffee breaks and lunches. They do not include Hotel accomodation, dinners and travel expenses.

To register, please send:• registration form duly filled out (even when sponsored by a Pharmaceutical Company)• privacy statement and consent to the use of personal data (as in the back of the form)• payment

to Accademia Nazionale di Medicina - Galleria Ugo Bassi 2, 40121 Bologna (fax 0039 51 0569162 – e.mail: info.bologna@accmed.org), within August 25th, 2018.

Online registration is possible on the website http://meettheprofessor.accmed.org.

By submitting the form and the payment, your registration is completed with the exception of specific decisions of the Meeting Secretariat.Incomplete registration will NOT be admitted.The registration will be confirmed by e-mail, please put your e-mail address on the registration form.

CANCELLATION• If the participants minimum number is not reached, Accademia Nazionale di

Medicina will advise by a written communication and proceed with the total refund of the fee.

• In order to cancel please give advise with a written communication to Accademia Nazionale di Medicina within 10 days from the beginning. A 70% of the registration fee will be returned. Any cancellation after that deadline will not be reimbursed.

Registration

Meeting VenueCentro Congressi Papa LucianiVia Forcellini 170/APadua

How to reach the meeting venue:Radio taxi: 049 651333The Congress Centre Papa Luciani has a large and free parking.

With the patronage ofINSTITUTIONS

SCIENTIFIC SOCIETIES

Comune di Padova

With the unconditional contribution of

BRONZE SPONSOR

CONTRIBUTORS

› AMGEN› CLOVIS ONCOLOGY IT› GENOMIC HEALTH INTERNATIONAL› IPSEN› TAKEDA

SILVER SPONSOR

Sponsored by

ACCADEMIA NAZIONALE DI MEDICINA

www.accmed.org

General Manager: Stefania Ledda

Organizing Partner

Forum ServiceVia Martin Piaggio 17/6

16122 Genova

Information:http://meettheprofessor.accmed.org

Ph. +3951 0569163 – 6360080Fax +3951 0569162

info.bologna@accmed.org

Hotel bookingbooking@forumservice.net

Ph. +391083794244Fax +391083794260