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Research Article: New Research | Integrative Systems
Temporal Regulation of GABAA Receptor Subunit Expression: Role in Synapticand Extrasynaptic Communication in the Suprachiasmatic Nucleus
Functional GABAA receptor rhythms in the SCN
James C. Walton, John K. McNeill, Khallyl A. Oliver and H. Elliott Albers
Neuroscience Institute and Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA 30303,USA
DOI: 10.1523/ENEURO.0352-16.2017
Received: 28 November 2016
Revised: 11 April 2017
Accepted: 12 April 2017
Published: 21 April 2017
Author Contributions: JCW and HEA designed the research, analyzed the data, and wrote the manuscript.JCW, JKM, and KAO performed the research.
Funding: HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)100000065F32NS092545
Funding: HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)100000065R01NS078220
The authors declare no competing financial interests.
National Institutes of Health grant R01NS078220 to HEA and F32NS092545 to JCW.
Correspondence should be addressed to James C. Walton, Neuroscience Institute and Center for BehavioralNeuroscience, Georgia State University, PO Box 5030, Atlanta, GA 30303, USA, E-mail: [email protected]
Cite as: eNeuro 2017; 10.1523/ENEURO.0352-16.2017
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Experiment 1: Effects of GABAA receptor subtype-specific agonists on phase
resetting.
in vivo
Experiment 2: GABAA receptor subunit gene expression in the SCN.
Experiment 3: GABAA receptor subunit protein expression in the SCN.
Statistics.
t
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p
Experiment 1: Phase shifting effects of GABAA agonists.
F p
F p
F p
p
p
Experiment 2: GABAA receptor subunit gene expression in the SCN.
p
t
t p
t
p
t p
t p
Experiment 3: GABAA receptor subunit protein immunoreactivity in the SCN.
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Treatment vs Treatment p
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DORSAL CENTRAL POSTERIOR
DORSAL CAUDAL
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VENTRAL CENTRAL ANTERIOR
VENTRAL CENTRAL POSTERIOR
VENTRAL CAUDAL
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