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2nd Annual Meeting and 1st Review of the FP7 project:

“AnThocyanin and polyphenol bioactives for Health Enhancement through Nutritional Advancement”

ATHENAATHENA245121

18 – 20 June 2012, Campobasso, ItalyUniversità Cattolica del Sacro Cuore, Fondazione "Giovanni Paolo II," Largo Agostino Gemelli, 1

86100 Campobasso, Italy

AGENDA09:00-09:15 MONDAY 18th JUNE

Introduction Isabelle de Froidmont-GörtzResearch DG, European Commission

09:15-09:45 General overview of ATHENA Prof. Cathie MartinCoordinator, John Innes Centre (JIC), Norwich, UK

09:45-11:15 WP2: Mechanisms of action of anthocyanins and related polyphenols in protecting against chronic diseases – overview of WP2 progress for M1-18Presentation of the tasks:

Prof. Michel de Lorgeril Université Joseph Fourier (UJF) Grenoble, France

2.1 Determination of how anthocyanins limit weight gain/fat development

Prof. Marco GiorgioInstituto Europeo di Oncologia SRL (IEO),Milano, Italy

2.2 Determination of how dietary anthocyanins and other polyphenols interact with the metabolism of essential fatty acids in animals to offer cardioprotection and to protect against the Metabolic Syndrome and obesity

Prof. Michel de Lorgeril, (UJF)

2.3 Determination of how dietary anthocyanins reduce the induction and progression of cancer

Prof. Chiara Tonelli/Dr Katia Petroni, Università Degli Studi di Milano (UMIL), Milano, ItalyDr Veena Talagavadi (Pelicci Group), European Institute of Oncology (IEO), Milano, Italy

2.4 Integration of the data on the impact of dietary anthocyanins and related polyphenols on the mechanisms of health promotion

Prof. Chiara Tonelli/Dr Katia Petroni, (UMIL)

Questions- discussion11:15-11:30 Coffee Break

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11:30-13:00 WP1: Benefits and risks of anthocyanins and related polyphenols in the diet - overview of WP1 progress for M1-18Presentations of the tasks:


1.1 Determination of the dose response to anthocyanin phytonutrients and whether anthocyanins from different food sources are equivalent


1.2 Assessment of how well anthocyanins perform in promoting health compared to other polyphenol phytonutrients such as stilbenes, isoflavonoids and catechins.

Prof. Cathie Martin, JIC

Questions- discussion13:00-13.45 Lunch Break13.45-15.15 WP3: Investigation of whether

dietary anthocyanins and related polyphenols are more effective as food or pharma – overview of WP3 progress for M1-18Presentations of the tasks:

Prof. Robert Hall, Stichting Dienst Landbouwkundig Onderzoek (DLO)

3.1 Development of a microbial system for high level anthocyanin production

Prof. Robert Hall/Dr Jules Beekwilder, DLO

3.2 Purification of anthocyanins from tomato, maize and Citrus in large enough amounts for feeding studies to determine the influence of nutritional context on the health-promoting effects of dietary polyphenols

Dr Paolo Rapisarda, Consiglio per la Ricerca e Sperimentazione in Agricoltura (CRA-ACM)Acireale, Italy

3.3 Comparison of the bioavailability of anthocyanins and other polyphenols in different foods and in dietary intervention studies

Prof. Maria Benedetta DonatiUniversità Cattolica del Sacro Cuore (UCSC-CB)

Tasks 3.3 (above) and 3.4 Development of methods for enhancing the bioavailability of polyphenols

Dr Esra Çapanoğlu GüvenIstanbul Teknik Universitesi (ITU)Istanbul, Turkey

Questions- discussion15.15-15.30 Coffee Break15.30-17:00 WP4: Effects of dietary anthocyanins

on promoting human health – overview of WP4 progress for M1-18 Presentations of the tasks:

Dr Paul Kroon, Institute of Food Research (IFR)Norwich, UK

4.1 Human intervention studies to determine the influence of dietary anthocyanins on cardiovascular disease.

Paul Kroon, IFR

4.2 Epidemiological study to determine interaction between anthocyanin consumption, genetic structure and HDL levels in humans

Prof. Daniele Cusi, KOS Genetic SRL (KOS)Milano, Italy

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4.3 Development of high anthocyanin breakfast bars using corn bran from tropical maize for assessing the role of anthocyanins in health promotion in humans, and providing ‘healthy foods’ for consumers.


4.4 Study of the effects of dietary anthocyanins on breast cancer and the side-effects of radiotherapy

Prof. Maria Benedetta Donati Università Cattolica del Sacro Cuore (UCSC-CB)Campobasso, Italy

Questions- discussionEnd of first day and before dinner:“Complimentary” local wine and cheese tasting offered by the Associazione Sommelier Molise.

9.00-10.30TUESDAY 19th JUNEWP5: Project management and dissemination – overview of WP5 progress for M1-18Presentations of the tasks:

Prof. Cathie Martin, Coordinator (JIC)

5.1 Strategic direction Prof. Cathie Martin, Coordinator (JIC)

5.2 Project monitoring Prof. Cathie Martin, Coordinator (JIC)

5.3 Administrative and Financial Management

Anita Bounds, Project Manager, JIC

5.4 Knowledge management and dissemination of knowledge

Dr Marialaura Bonaccio, Communications Unit, (UCSC-CB)

Questions- discussion10.30-10.45 Coffee break10.45-11.15 Overall discussion11.15 Close of the Meeting and Review

Lunch at Centrum Palace Hotel followed by lab visit to Laboratori di Ricerca, Fondazione di Ricerca e Cura "Giovanni Paolo II" and if time permits a tour of some Campobasso highlights, e.g. an archeologic site (Sepinum) (20 mins away) or a mediaeval beautiful burg, Oratino (10-15 minutes), according to the weather and the time available.

EVENING CLOSING SOCIAL DINNER including visit to the factory at ‘La Molisana’WEDNESDAY 20th JUNE - morning Reviewers complete their report;

Project partners return home

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