tell it straight 2016: blocking the roads to resistance in breast cancer
TRANSCRIPT
Blocking the roads to resistance in breast cancer
Neil Conlon
Breast cancer is the 2nd most common cancer in women
One in ten women diagnosed every year…
Breast cancer is more than one diseaseHER2-positiveHormone receptor
positiveTriple
Negative
HER2-positive(~20%)
AggressivePoorer prognosis
Other breast cancers
400 cases/year
CellHER2
Cell Surface
Cell Growth
HER2
CellDeath
100,000’s have benefited from HER2-targeted drugs
?Drug
Resistance
CellDeath
My Research
Look for druggable weaknesses
Resistance is futile!
Thanks for listening!