UNE CLASSIFIED ADVERTISEMENTS

DEADLINES: Ads are due by Thursday, 10 a.m., 2weeks prior to the issue date. Science publisheseach Friday, except the last Friday of the year.Advertisements must be submitted in writing.

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SCIENCE Cmled AdvetWIng1333 H Stret, N.W., Room 940

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HOW TO CALCULATE RATE FOR Cl ASIFIEDAD: Ads are $41 per line with a $410 minimum. Oneline equals 52 characters and spaces; centeredheadings equal 32 characters and spaces.

To ESTIMATE ad cost, count total number of 52character lines and multiply by $41 to find approxi-mate cost of ad per week. Each line of centeredheading counts as one line. Also count one line forwhite space between headline and first line of text;all partial lines are also counted as full lines (includ-ing all centered reply information).

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BOXES AND LOGOS: Any line classified ad can beboxed and/or published with logo to increase itsvisibility on page. Since the box takes up additionalspace, one line now equals 48 characters andspaces: two additional lines will be added to allowfor top and bottom rules. Logos are billed accordingto the number of lines needed to fit logo in space.

CANCELLATIONS: Deadline for cancellation is 10a.m., Tuesday, 10 days prior to issue date.

DISPLAY PERSONNEL ADVERTISEMENTS

For rates, deadlines, and information about fraction-al display ads (all ads 1/6 page and larger) and allmarketplace listings of available products and serv-ices, contact:

1515 BrawyNew York, NY 1003

Telephone: 212-730-1050FAX: 212-362-3725

CONDITIONS: Personnel advertising is acceptedonly with the understanding that the advertisers donot discriminate among applicants on the basis ofrace, sex, religion, age, color, national origin, hand-icap, or sexual preference. Science reserves theright, at its discretion, to decline to publish adver-tisements submitted to it and to decline classifica-tions which it considers misleading.

POSITIONS OPEN

ASSISTANT PROFESSOR. Agricultural Engineer-ing Department, The University ofMaryland. A tenure-

track 10-month faculty position with 100% teaching inthe area of ecological and biological systems engineering

including water quality/water chemistry is available. Ap-pointee IS expected to teach undergraduate and graduatecourses in agricultural engineering and natural resources

management curricula and develop research projects on

ecological or biological systems engineering. A Ph.D. inbiological engineering (and/or combined biology andengineering) or cosely related fields is required. Appli-

t1991 or until position is A16dApplicants should academic tral p and

of reference to: Dr. Add

geergg UniversityAnEqal/iCoo Park,A D A0742.An Equal O nity/nA~tive Action Employw.

VERTEBRATE PHYSIOLOGIST-ANATOMISTThe Department of Biology of Wilkes University

offers a full-time, ASSISTANT PROFESSOR facultyposition commencing on 28 August 1991. The success-

ful candidate will be d to teach courses in humananatomy and physiology for nursing students, a sopho-more level course in comparative anatomy, upper level

courses in mammalian physiology and histology and to

take part in general biology laboratory instruction. While

excellence in teaching is the principal objective of thedepartment, a research program including involvementwith advanced undergraduates is expected.

This is a tenure-track position, but 1-year appoint-ments will be considered.

Applicants must submit full curriculum vitae, threeletters of recommendation, reprints of recent publica-tions, and a statement of tea7; philosophy. Due totime constraints, the deadline for receipt of applicationsis 22 July 1991.Wikes is a comprehensive regional university with a

strong science and engineering component and with a

wide range of undergraduate programs as well as a

limited number of masters degree programs. The uni-versity is located within the historic district of the city ofWilkes-Barre, along the Susquehanna River and has anundergraduate enrollment of approximately 2000 stu-dents. There are approximately 200 biology majors, ofwhom some 70% are in various premed programs. Theplacement of alumni to graduate and professional pro-grams has been very strong. Submit materials to:

Dr. Lester Turocz ima

DeatofBilg

,W UniversityW k-Barre, PA 1766

Wikes is an A~ffrmative Action/Equal OpportunityEmployer.

BIOMOLECULAR ENGINEERINGCOLLEGE OF ENGINEERING

AND TECHNOLOGYOHIO UNIVERSITY

Applications are invited for a tenure-track facultyposition in biomolecular engineering at the rank ofASSISTANT PROFESSOR. Applicants should have a

Ph.D. with an outstanding academic record in an engi-neering or related discipline. The successful candidatewill participate with an active group in extending thebiomolecular engi ern area within the College ofEngineering and Technology and develop a researchprogram of national recognition on the synthesis ofrecombinant proteins and peptides, their large-scale pro-duction, and separation. A strong commitment to bothundergraduate and graduate education is expected. OhioUniversity has an established, internationally renownedprogram in molecular and cellular biology which, togeth-er with the Edison Animal Biotechnology Center, pro-vides a unique opportunity for the foundation of a highlysuccessful Biomolecular Engineering Program. A special

new building to house the program is already in theplanning stage and the new facufty will have the oppor-tunity to work closely with architects to provide astate-of-the-art engineering facility. Substantial starr-up

funds are available. A resume, a brief summar of re-

search experience and plans, and names of at east three

references should be sent to: Profesor W. P. Jepson,Chairman of Chemical Enineerig Deparent,Stocker Center, Ohio Univers, Athens, OH 45701.Applications will be accepted until 15 September 1991or until position is filled. Ohio University is an EqualOpportunity/Afrmative Action Employer.

92

BIOPHARMACEUTICS / PHARMACOKINET-ICS. The Division of Pharmaceutical Sciences seeks a

highly qualified individual with a Ph.D. degree to fill a

tenure-track position at the ASSISTANT OR ASSO-CIATE PROFESSOR level. Responsibilities includeteaching in both the professional and graduate degreeprograms and development of an active extramurallyfunded research program. Applicants should send curric-

ulum vitae, statement of research interests, and names

and addresses of three references by 1 August 1991 to:

Chair, Biopharmaceutics/Phcokinetics SearchCommittee, School of Pharmacy-C238, Universiof Colorado Health Sciences Center, 4200 Eat

Avenue, Denver, CO 80262. The University ofColoradois committed to Equal Opportunity and Afirmative Action.

DEPARTMENT OF MICROBIOLOGYAND IMMUNOLOGY

LOYOLA UNIVERSITY CHICAGO

The Department ofMicrobiology and Immunology ofLoyola University Chicago has an immediate opening fora tenure-track virology position at the level o ASSIST-ANT OR ASSOCIATE PROFESSOR. While thesuccessful candidate is expected to obtain extramuralfunding, the salary is not dependent upon grant funds.Please submit curriculum vitae and the names and ad-dresses of three persons from whom letters of referencecan be solicited to:

Katherie L. Knight, Ph.D., ChairDepartment of Micwbiology and Immunology

LoyosUnversty edical Center

2160 South First Avenue

Maywood, IL 60153Loyola University Chicago is an Equal Opportunity

Educator/Employer.

DIRECTOR, TRANSPLANTATION RE-SEARCH LABORATORY. Seeking a Ph.D. in chem-istry, immunology, or molecular biology with interestand experience in transplantation science to direct re-search laboratory within an extremely active liver trans-plant program. Newly developed facilities, with supportfrom established liver research unit. Need an innovativeself-starter to take charge. Interested candidates shouldsend their risumes to: Charles Miller, M.D., Director,Liver Transplantation, The Mount Sinai MedicalCenter, Box 1104, One Gustave Levy Place, NewYork, NY 10029.p

A position in Batavia Area Office located at FermiNational Accelerator Laboratory to serve as PROJECTMANAGER for the Fermilab Main Injector construc-tion project. Equal Opportunity Employer. U.S. citizen-ship required. Position is graded at GM-15; salary rangesfrom low $60,000's to low $80,000's. Candidates musthave an engineering degree. Send rtsumes no later than

2 August 1991 to: U.Departent of Energy, Fed-eral Peonne Branch/Ms. Lyon, 9800 Cam Avenue,Argonne, IL 60439.

SCIENCE, VOL. 253

AMVAX, Inc., a human pediatric vaccine re-

search, development, and manufacturing compa-ny, has position openings.

PRODUCTION DIRECTORThe individual will be responsible for directing

and managing the production of bacterial vac-cines. The successfuf candidate must have a M.S.1Ph.D. and a minimum of 5 years ofexperience inthe production of bacterial products under GMPconditions. The individual will report directly to

the vice president of manufacturing.

RESEARCH ASSOCIATE-FERMENTATION

Qualified candidate must have a B.S./M.S. inmicrobiology and a minimum of 3 years ofexperience m small scale and large scale fermen-tation. A knowledge ofGMP and experence in

polysaccharide purification would be highly ben-eficial. Equal Opportunity Employer. We offerhighly competitive salaries and benefits. Sendcurriculum vitae/resume to:

AMVAX, Inc.Personnel Director

12040 Indian Creek CourtBeltsille, MD 20705

Telephone: 301470-6100;PAX: 301-470-6198

h

POSITIONS OPEN

1 1

POSITIONS OPEN

ECOLOGICAL MODELING/ENVIRONMENTAL TOXICOLOGY

A tenure-track research/teaching appointment up tothe level of PROFESSOR is available in ClemsonUniversity's Department of Environmental Toxicologyand The Institute of Wildlife and Environmental Toxi-cology. Responsibilities will involve modeling biolocalmovement and effects of contaminants in wildlife toinclude prediction ofeffects from multiple contaminants.Models will be based on toxicology research data fromvertebrate and invertebrate species. Ability to integratefate and effects models and population models is essentialas is advanced computer skills. The integration of eco-systems modeling with GIS technology to develop mod-eling processes that involve geographic and landscapevariables is essential. Requirements include Ph.D. inappropriate discipline and excellence in research as dem-onstrated by publication record and other achievements.Send curriculum vitae, letter of application, and list of

references by 19 July 1991 to: Dr. Raymond Noblet,Department of Environmental Toxicology, P.O. Box709, Pendleton, SC 29670.

Equal Opportunity/Afirmative Action Employer.

THE INTERNATIONALATOMIC ENERGY AGENCY (IAEA)

Seeks DEPUTY DIRECTOR of the Joint FAO/IAEA Division of Nuclear Techniques in Food andAgriculture.

Applicants should hold a Ph.D. or equivalent degree inone ofthe agricultural sciences with thorough knowledgeand experience with isotope and radiation applications magnicuftural research. A minimum of 15 years of experi-ence in scientific administration at the national level;experience in international administration desirable.

Tax-free emoluments of approximately U.S.$67,500per annum. Additional allowances for dependents. Initialcontract for 3 years. Six weeks annual leave. Travel andremoval expenses paid. Applicants should send theircurriculum vitae quoting Vacancy Notice No. 91/029to: The Divsion of Personnel, International AtomicEnergy Agency, P.O. Box 100, Wagramentrasse 5,A-1400 Vienna, Austria, before 21 September 1991.

CURATOR/SYSTEMATISTPosition for ASSISTANT CURATOR of the U.S.

National Tick Collection, Institute of Arthropodologyand Parasitology (IAP) Georgia Southern University.Candidate must have Ph.D. in a zoological science,training in modern systematic theory and practice, back-ground in taxonomy and systematics of taxa of medicallyimportant arthropods (preferably ticks), and experiencein computer applications. Duties include curating theNational Tick Collection, providing tick identificationservice, conducting and publishing original research onticks, and obtaining external grant support. Salary com-petitive depending upon qualifications. Send letter ofapplication, names of three references, curriculum vitaeand official copy of educational transcripts to: J. H.Oliver, Jr., Director, IAP, Georgia Southern Univer-sty, Landrum Box 8056, Statesboro, GA 30460-8056. Deadline: 1 September 1991. Position available 1October 1991. Georgia Southern is an Affirmative Action/Equal Opportunity Institution. The names ofapplicants andnominees, r6sumes, and othergeneral nonevaluative informa-tion are subject to public inspection under the Georgia OpenRecords Act.

PROGRAM ADMINISTRATOR-PROGRAMSSIGMA XI

THE SCIENTIFIC RESEARCH SOCIETY

Develop and expand several of the societyes programs,including grants-rn-aid of research; regional and nationallectureships; special lectures; science, mathematics, andengineering education; and science and society. Essentialqualifications include broad scientific education, a talentfor writing, and experience in writing and managinggrant proposals. An interest or involvement in scienceeducation or science and society topics is advantageous.A Ph.D. or equivalent degree is required. Some travel isinvolved. This position may be of particular interest toresearch scientists with 3 to 5 years of work experience.Position available 1 September 1991, or until filled. Sendrisum6 and salary requirements to: Dr. Evan R Fer~u-son, Director of Programs, Sigma Xi, The scientificResearch Society, P.O. Bo 13975, R archTrianglePark, NC 27709. Sigma Xi is an Equal OpportunityEmployer.

5 JULY 1991

Immunologist/ImmunotoxicologistThe Procter & Gamble Com-pany has an entry-level open-ing in Cincinnati, Ohio for animmunologist with Ph.D. or

postdoctoral training. Thisopening is in the HumanSafety Division at the MiamiValley Laboratories.Research experience inimmunology is required toestablish a research programin the area of immunotoxi-cology with special attentiondirected towards under-standing regional immuneresponses. In addition,experience in the areas ofmolecular biology and/or cellbiology techniques isdesirable.Procter & Gamble is a world

leader in the research, devel-opment, and manufacture ofconsumer products. We offera highly competitive salary, afringe benefit package in thetop 5% of U.S. firms, andexcellent opportunities forpersonal and career growth.Candidates must be presentlyauthorized to work in the U.S.on a full-time basis. Resumes,with a list of publications,should be sent to:

Dr. T. J. Logan, ManagerPh.D. RecruitingImmunology Position, Box FGThe Procter & Gamble Co.Miami Valley LaboratoriesP.O. Box 398707Cincinnati, Ohio 45239-8707Procter& Camble isan

EQUAL OPPORTUNI1YFMPIOYFR

U-____________________________~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~m- m- m- m m-

POSITIONS OPEN

RICE UNIVERSITYEXECUTIVE DIRECTOR FOR THEINSTITUTE OF BIOSCIENCESAND BIOENGINEERING

Position in institute with responsibilities for coordi-nating, developing programs, grants, and informationmaterials. Responsible and creative person required,Ph.D. in biosciences or bioengineering, plus research andsome administrative experience (5+ years) required.Send letter ofapplication, curriculum vitae, and names ofreferences to: Jan West, Rice University, EmploymentOffice, P.O. Box 2666, Houston, TX 77252. Tele-phone: 713-527-4074, Equal Opportunity Employer!Afirmative Action, M/F/V/H.

DIRECTOR OF MOLECULAR PATHOLOGY.The Department ofPathology, Emory University Schoolof Medicine, is seeking an M.D. or Ph.D. to run themolecular pathology laboratory at Grady Memorial Hos-pital. The successful candidate will have training and atleast 3 years of experience in nucleic acid-based diagnos-tic techniques including blotting and amplification tech-nology. Demonstrated experience in applications ofthesetechniques to diagnostic laboratory medicine as well as ineffective collaboration and communication with clini-cians and housestaff is xcted. The candidate mustshow evidence of accomplishment in a basic or clinicalresearch program. Closing date for receipt ofapplicationsis 15 August 1991. Applicants should submit recentcurriculum vitae and the names of three references to:Kenneth W. Sell, M.D., Ph.D., Professor and Chair-man, Department of Pathology, 703 WMB, EmoryUniversity, Atlanta, GA 30322. Emory University is anAffirmative Action/Equal Opportunity Employer.DIRECTOR Rhode Island Atomic Energy Commis-

sion (RIAEC), Rhode Island classified civil service posi-tion. Principal task is oversight of operation and utiliza-tion of RI Nuclear Science Center and its 2-MW research

reactor. Successful applicant will be active participant in

upgrade and conversion of reactor to LEU fuel. Ad-vanced degree required in science or engineering withseveral years of appropriate experience. Send resumeincluding references and salary history to: Chairman,

RIAEC, South Ferry Road, Narragansett, RI02882-1197.

INFORMATION SPECIALISTFOR THE BASIC SCIENCES

The William H. Welch Medical Library, The JohnsHopkins University School of Medicine, invites applica-tions for this position which provides a full range oflibrary and information services to basic sciences depart-ments. Primary responsibilities include: identification ofproblems and needs faced by scientists and students whenretrieving and managing information from scientific da-tabases, consultation and instruction to solve those prob-lems and needs, and participation in the library's instruc-tional program. Applicants should have a graduatedegree in the biological/life sciences and a masters degreein library science, experience with teaching and onlinesearching, and an understanding of research and academ-ic environments.The library offers a competitive salary and benefits

package. Applicants should submit an application letter

and curriculum vitae to: Craig Mulder, The WelchMedical Library, The Johns Hopkins UniversitySchool of Medacine, Baltimore, MD 21205-2113.TheJohns Hopkins University is an Equal Opportunity!Affirmative Action Emptoyer.FACULTY POSmIION. Department of Basic Phar-

maceutical Sciences. Applications and nominations are

sought for a tenure-track position at the ASSISTANT/ASSOCIATE PROFESSOR level in the Departmentof Basic Pharmaceutical Sciences (rank and salary nego-tiable). Candidates with distinguished records of schol-

arship and extramural funding may be considered for

appointment at the level of professor. Applicants should

have a Ph.D. or equivalent in one of the pharmaceuticalsciences with research interest in site-directed drug deliv-ery, molecular/cell biology, or pharmacodynamics. The

successfulo applicant will teach pharmacotherapeutica and

should have a commitment to developing an extramurally

funded research program. Send curriculum vitae, state-

ment of research interests, and the names of three

references to: Carl J. Malanga, Ph.D., West VirginiaUniversity (WVU), Schooof Pharmacy, Morgan-town, WV 26506. WVU is an Affirmative Action/EqualOpportunity Institution.

94

POSITIONS OPEN

AR i seeking a RESEARCH LEADER/LOCA-TION COORDINATOR to lead the research programat the Foreign Disease-Weed Science Research Unit inFrederick, Maryland. The mission of the unit is researchon foreign plant pathogens, which threaten Americanagriculture, use of plant pathogens for biological weedcontrol, and interaction of herbicides and plant growthregulators for enhanced weed control. Degree in plantpathology or plant physiology or a related discipline;1nowledge of plant pathology and plant disease researchmethods; ability to manage a research program andprovide leadership; and ability to communicate m orderto interact with scientists, agencies, and public are re-quired. Knowledge of plant physiology and workingwith diseases under full quarantine are desirable. Must bea U.S. citizen. Salary range $44,000 to $69,000 com-mensurate with experience. For information on the re-search program and position, contact: Dr. Arthur L.Schipper at 215-233-6668. For information on appli-cation procedures/forms, contact: Beverly Webert at301-344-1921. Applications in response to this adver-tisement must be marked 1N058, and be postmarked by14 August 1991.USDA/ARS is an Equal Opportunity Employer.

; L Agricuftur United StatesRiseech Deptmen of

ASeoe AgfiutureENVIRONMENTAL STUDIES AND TOXI-

COLOGY. The Board on Environmental Studies andToxicology (BEST) of the National Research Council(NRC) is seeking aPROGRAM OFFICER for a studyon air pollutants. Responsibilities include working with acommittee, directing work of panels, and providingintellectual overview of report. Requires an M.D. orequivalent and at least 3 years of experience in research,teaching, or administration in toxicology, epidemiology,pharmacology, environmental health science, or a relatedscience. Must understand utilization of scientific infor-mation in decision-making and have ability to integratedata from a wide variety of disciplines. Please submitcurriculum vitae and names of references to: NRC/BEST,HA354-RT, 2101 Constitution Avenue, NW,Washington, DC 20418. Equal Opportunity Employer.FACULTY POSITION-GROSS ANATOMYThe Department of Cellular and Structural Biology at

The University of Texas Health Science Center at SanAntonio invites applications for a tenure-track facultyposition at the ASSISTANT OR ASSOCIATE PRO-FESSOR level. Applicants must have a doctoral degreeand previous teaching experience in gross anatomy butshould be qualified to teach in all of the anatomicaldisciplines. Preference will be given to individuals with a

productive research program capable ofgenerating extra-mural support. Salary will be commensurate with quali-fications. Submit a letter of application, curriculum vitae,and the names of three references to: Dr. Barbara H.Bowman, Chair, Department of Cellular and Struc-tural Biology, The University ofTexas Health ScienceCenter at San Antonio, 7703 Floyd Curl Drive, SanAntonio, TX 78284-7762.An Equal Opportunity/Affirmative Action Employer.

BIOCHEMISTRY/MOLECULAR BIOLOGYTEXAS A&M UNIVERSITY

The Department of Biochemistry and Biophysics isseeking applications for FACULTY POSITIONS.These are 12-month, tenure-track positions to be filled bySeptember 1991. Academic rank is open and dependentupon experience and qualifications. Outstanding individ-uals having research interests dealing with the molecularaspects of regulation, structure, mechanism, or functionin microbial, animal, or plant systems are sought. Inaddition to research, participation in the department'sundergraduate and graduate teaching programs will berequired. A Ph.D. in either biochemistry or a relatedfield,rPlus appropriate postdoctoral experience, is re-

Applicants should send curriculum vitae, list of publi-cations, a brief description of current and future researchdirections, and have three letters of reference sent to: Dr.Robert D. Wells, Department of Biochemistry andBiophysics, Teas A&M University, College Station,TX 7843-2128.

The Texas A&M University System is an AffirmativeAction/Equal Opportunity Employer.

POSITIONS OPEN

DNA AND PROTEINCHEMISTRY FACILITY MANAGERS

Two positions are available for individuals to managethe DNA/Protein Microchemical Core Facility (MCF) atSan Diego State University (SDSU). The DNA Chem-istryManager will perform oligonucleotide synthesis andpurification, as well as DNA sequencing and computeranalysis of DNA and RNA. The Protein ChemistryManager will perform peptide synthesis and sequencing,as welas s protein purification and computer analysis ofprotein sequences. Applicants for these positions shouldhave a master's or doctoral degree in a molecular oranalytical science, as well as extensive experience with theequigment required to perform the relevant analyses and

demonstrated ability to maintain equipment, super-vise personnel, and manage a fee-for-service facility. TheMCP is designed to provide for instructional and re-search support for individuals participating in the Cali-fornia State University Program for Education and Re-search in Biotechnology (CSUPERB). Salary rangeapproximately $2915 to $3512, depending on qualifica-tions. Applicants should submit a resume and the namesof tree references to: SDSU, Personnel Services, SanDiego, CA 92182-0741. For more information tele-phone: 619-594-4646.

Equal Employment Opportunity/AjlrmativeAction/Title1X Employer.

FACULTY POSITIONSIN MOLECULAR BIOLOGY

AND MOLECULAR PHARMACOLOGYThe Department of Pharmacology and Molecular Bi-

ology at The Chicago Medical School is initiating thethird phase of faculty recruitment for tenure-track posi-tions at all levels. Preference will be given to applicantswho have established an independent research programin any aspect of gene expression and molecular pharma-cology.The school is located in a modem facility adjacentto the very pleasant North Shore community of LakeBluff, 38 miles from downtown Chicago and yet easilyaccessible by car or train, with proximity to forestpreserves, Lake Michigan, and cultural attractions. Thedepartment is now in an exciting stage of growth anddevelopment and has already recruited faculty of highcalibre. Excellent core facilities and strong graduateprogram (Ph.D. and M.D./Ph.D.) with substantial finan-cial support are available. Salary, start-up funds, andother benefits highly competitive. Please send curriculumvitae, research plans, and three names for reference to:Dr. Samson T. Jacob, Chairman, DCpartnent ofPharmacology and Molecular Biology, the ChicagoMedical School, 3333 Green Bay Road, North Ch-cago, IL 60064. The Chicago Medical School is an EqualOpportunity/Affirmative Action Employer.

FACULTY POSITIONPROKARYOTIC MICROBIOLOGIST

Applications are invited for two tenure-track positionsin the Department of Microbiology, University of Penn-sylvania School of Medicine, to commence 1 July 1992.Candidates at the ASSISTANT PROFESSOR level are

preferred, but others will be considered. Applicantsshould have an established research interest in prokary-otic molecular genetics, physiology, or pathogenesis.Candidates should have at least 2 years of postdoctoralexperience and are expected to demonstrate the potentialto develop a strong, independently funded researchprogram. Teaching responsibilities include participationin a team-taught microbiology course for medical stu-

dents and prokaryotic molecular genetics for graduatestudents. Send curriculum vitae, names of at least threereferences, and a description of past research accomplish-ments and future plans to: Dr. Daniel Portnoy, SearchCommittee, Department ofMicrobiologyUniversitofPennsylvania School ofMedicine, Pladlphia, PA19104-6076. Application deadline: 30 October 1991.An Equal Opportunity/Affirmative Action Employer.POSTDOCTORAL POSITION. At Stanford Uni-

versity Center for conservation biology. Plant ecologistwith research interests in conservation biology sought forrenewable 12-month position. Strong quantitative expe-rience, especially in applications of science to practicalconservation problems. Ph.D. and at least two peer-reviewed papers required. Send letter, curriculum vitae,names/teckphone numbers of three references, and state-ment of research interests by 12 August 1991 to: DennisMurphy,Derent ofBiological Sciences, StanfordUniversity, Stanford, CA 94305.

SCIENCE, VOL. 253

z

INFLAMMATION &TISSUE REPAIR

SmithKline Beecham, a world leader in pharmaceu-tical research has the following opportunities forPh.D. trained scientists in the expanding Inflamma-tion and Tissue Repair (ITR) Product SupportDepartment. This group is responsible for world-wide non-clinical studies for ITR products that are

in late-phase clinical trials or currently marketed.

SCIENTIFIC ADVISORThis scientist will oversee worldwide non-clinicalITR studies and answer all technical inquiries re-

garding products in this category. Responsibilitiesinclude designing and executing experimental pro-

tocols in accordance with strategic goals and educat-ing the scientific community on the advantages ofSB products through published papers and lectures.Requirements include a Ph.D. in physiology or

pharmacology, postdoctoral experience in inflam-mation or related discipline and five years' postdoc-toral experience. Experience with small animalmodels and isolated tissue and isolated cell prepara-

tions is preferred. Supervisory and industry experi-ence desired. (Position #G-0171).

ITR INVESTIGATORThis scientist will design and execute experimentalprotocols, present experimental results at U.S. andinternational meetings, and publish research inpeer reviewed journals. This individual will providetechnical advice to Marketing, Sales Training andProduct and Project teams as necessary. Require-ments include a Ph.D. in physiology or pharmacol-ogy, postdoctoral experience in inflammation or

related discipline and experience with a variety ofanimal models and isolated tissue and cell prepara-

tions. (Position #G-0172).SmithKline Beecham offers a competitive

salary, benefits and relocation package and a stimu-lating environment in which to excel and grow.

Our state-of-the-art research facility is located insuburban Philadelphia, near Valley Forge, PA. Forconfidential consideration, forward your C.V. to:

T. Gallagher, Senior Employment Administrator,(Position #), SmithKline Beecham Pharmaceuticals,P.O. Box 1539, King of Prussia, PA 19406. EqualOpportunity Employer, M/F/H/V.

SmithKItne BeechamPharmaceuticalsI

CHANCELLORUNIVERSITY OF NEBRASKA

MEDICAL CENTERand VICE PRESIDENT

UNIVERSITY OF NEBRASKA

The University of Nebraska invites applications andnominations for the position of Chancellor of the Univer-sity of Nebraska Medical Center (UNMC) and VicePresident of the University of Nebraska. The Chancelloris the chief administrative officer of a modern, innovativemedical center which is a major health resource for theState of Nebraska and surrounding region. In certaintargeted areas, such as liver and bone marrow trans-plantation and cancer research, UNMC is a nationalresource.

The Chancellor of the medical center is appointed byand reports to the President of the University ofNebraska. Responsible for providing leadership for allinstructional, research and service programs ofUNMC, the Chancellor also is expected to develop andmaintain effective relationships with all appropriate con-stituencies.

One of four campuses of the Universtiy of Nebraska,which has a total enrolment of 50,000, UNMC servessome 2,400 students in colleges of medicine, nursing,pharmacy and dentistry. The School of Allied Health is apart of the College of Medicine. In addition, UNMC offersgraduate studies and research opportunities in a varietyof basic science, medical science and health care areas.University Hospital is an integral part of UNMC and is amajor midwest referral center. UNMC's Eppley Institutefor research in Cancer and Allied Diseases is a desig-nated cancer research center of the National CancerInstitute. The Meyer Rehabilitation Institute is a centerfor the diagnosis and treatment of children and adultswith developmental, genetic, physical and emotionaldisabilities.

The University seeks an individual with demonstratedleadership ability, a record of excellence in intellectualand academic performance, significant administrativeexperience in higher education and a personal com-mitment to education and research. An earned doctor-ate is desirable. A commitment to affirmative action isessential.

Initial screening of candidates will begin on or about July15, 1991 and will continue until the position is filled.Applications and nominations should be submitted to:

James 0. Armitage, M.D.Chairman

Search Advisory CommitteeUNIVERSITY OF NEBRASKA

3835 Holdrege StretLincoln, NE 68583-0745

The University of Nebraska is an affirmative action, equalopportunity employer which actively seeks and encouragesnominations and expressions of interest from women andminorities.

POSITIONS OPEN

INSTITUTE OF BIOSCIENCES ANDTECHNOLOGY

TEXAS A&M UNIVERSITY

Texas A&M University is establishing the Institute ofBiosciences and Technology (IBT) in the Texas MedicalCenter in Houston. The function of the IBT is to mergethe strengths of the Colleges of Agriculture and LifeSciences, Veterinary Medicine, and Engineering with thescientific and clinical strengths of the Texas MedicalCenter. All FACULTY in the Houston IBT will havepositions in academic departments in College Station.Academic rank is dependent upon experience and quali-fications. Outstanding individuals having research inter-ests dealing with a broad range of biomedical investiga-tions are sought. The 11-story IBT building is scheduledfor completion in September.

Applicants should send curriculum vitae, list of publi-cations, and a brief description of current and futureresearch interests and have three letters of reference sentto: Dr. Robert D. Wells, Director, Institute of Bio-sciences and Technology, Texas A&M University,College Station, TX 77843-2128.The Texas A&M University System is an Afirmative-

Action/Equal Opportunity Employer.

IMMUNOCHEMIST AND IMMUNOLOGIST.National Cancer Institute, National Institutes of Health(NIH), Public Health Service, is seeking applicants forthe following positions: IMMUNOCHEMIST: Towork closely with molecular biologists and immunolo-gists to define new strategies and methodologies for theradiolabeling and analysis of novel genetically engineeredforms of immunoglobulins and Ig-like molecules. Pref-erence for at last 3 years of postdoctoral training. IMMU-NOLOGIST: To analyze and define the host immuneresponse in antitumor active immunotherapy systemsusing recombinant vaccinia constructs, peptides, etc., andstudy the interactions of various effetor cell populationswith novel recombinant forms of Iges; will also interactwith molecular biologists in gene therapy expeints.Prefree for at least 3 years of p al training.Salary commensurate with experience. Please submitcurriculum vite, bibliography, and names of three ref-erences to: Dr. Jeey Sc Laboratory of TumorImmunoogy and Biolgy, National CancerInstit= t,Building 10, Room 8B07, NIH 9000 Rockville Pike,Betheda, MD 20892. U.S. ctizenship and/or pemanntresidey required pending upon tpe of aintnt. AnEqual Opponity Employer.

POSTDOCTORAL ASSOCIATE POSMITON. Toexamine the molecular genetics of alphavirus pathogen-esis. The relationship of virus structure and replication toinduction of disease is being investigated using full-length cDNA clones of Sindbis and Venezuelan equineencephalitis viruses. One goal of these studies is todetermine the molecular and cellular basis for the effect ofspecific mutations on viral pathogenesis. A second goal isthe informed development ofnew alphavirus vaccines. Awide range of projects is available within these researchcontexts, depending on the interests and training goals ofthe applicant. To apply, send curriculum vitae and thenames of three references to: Robert E. Johnston,Ph.D., Department of Microbiology and Immunolo-gy, University of North Carolina at Chapel Hill,CB7290 804 FLOB, Chapel Hill, NC 27599. TheUniversity of North Carolina is an Equal Employment!Affirmative Action Employer.

BEHAVIORAL PHARMACOLOGIST/TOXICOLOGIST

A POSTDOCTORAL POSITION in the Intramu-ral Research Award Fellowship or Visiting Fellow Pro-gram is available for basic and applied research in evalu-ating preclinical efficacy and safety of potential drugabuse treatment compounds. Particular focus is on treat-ments for cocaine and amphetamine abuse and toxicity inanimal models. The individual would work within a

laboratory consisting of behavioral pharmacologists andmedicinal chemists. Applicant, with a background inpharmacology or behavioral neuroscience, must havereceived a Ph.D. within the last 3 years. Send curriculumvitae, citizenship status, and three representative publi-cations to: Dr. J. M. Witkin, Drug DevelopmentGroup, NIDA Addiction Research Center, P.O. Box5180, Baltimore, MD 21224. NIDA is a drug-free andsmoke-free workplace. Equal Opportunity/Afirmative Ac-tion Employer.96

POSITIONS OPEN

POSTDOCTORAL POSMON. Available imme-diately for the study of novel mammalian G protein-linked serotonin receptor genes and their gene products.Several projects are available involving regulation ofgeneexpression or effector mechanisms, depending on mutualinterests. Prior experience in recombinant DNA tech-niques, cell culture, in situ hybridization or immunocy-tochemistry is highly desirable. U.S. citizenship required.Contact: Dr. Mark W. Hamblin, GRECC 182B,Seattle VA Medical Center, 1660 South ColumbianWay, Seattle,WA 98108. Telephone: 206-764-2308.Equal Opportunity Employer. Minorities are encouraged toapply.

POSTDOCTORAL POSMTION. Available 1 July1991 to participate in ongoing studies of molecularmechanisms of signal transduction. Familiarity with re-ceptor biochemistry and recombinant DNA technologydesirable. Projects employ molecular approaches to studyreceptor effector coupling, regulation, and function ofGprotein-linked receptors. Send resume and names ofthree references to: Dr. Gary R. Luthin, Departmentof Physiology, Mail Stop 409, Hahnemann Universi-ty, Broad and Vine, Philadelphia, PA 19102.Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSMON. To investigate thebiochemical and cellular mechanisms of a new antithrom-botic protein therapeutic. Ph.D. in biochemistry, molec-ular or cell biology and experience with one or more ofthe following: protein purification and characterization,regulation of gene expression, cell culture, cell receptors,cytokines. Salary to $35,000. Send curriculum vitae withnames and telephone numbers of three references to:Carolyn L. Orthner, Ph.D., American Red Cross,Holland Laboratory, 15601 Crabbs Branch Way,Rockwille, MD 20855. Equal Opportunity Employer,M/F/H/V.

POSTDOCTORAL POSTIMONPosition in the Department of Pharmacology is imme-

diately available, emphasizing studies on electrophysiol-ogy of inhibitory and excitatory amino acids. Experiencein the molecular expression of amino acid receptors inXenopus oocytes and the subsequent electrophysiologicalrecordings is highly desirable. Knowledge and applica-tion of patch damp techniques would also be an advan-tage. Send your curriculum vitae and names of threereferences to: Dr. D. Martin, Department of Pharma-cology, Box 3813, Duke University Medical Center,Durham, NC 27710. Duke University is an Equal Op-portunity/Affirmative Action Employer.

POSTDOCIORAL POSITION

Available in the study of platelets in clinical coagula-tion, cardiac surgery, and transfusion medicine. Currentresearch includes preservation of platelets for extendingshelf-life and characterization of membranous micropar-ticles released from platelets during activation. Studieswill be carried out in the laboratory of Arthur P. Bode,Ph.D. Must have background in applied science, prefer-ably with interest/experience in clinical pathology labo-ratory.Send curriculum vitae and three letters of reference to:

H. Thomas Norris, M.D., Department of ClinicalPathology and Diagnostic Medicine, Brody 1S-08,East Carolina University School of Medicine, Green-ville, NC 27858. An Equal Opportunity/Affirmative Ac-tion University. Applicants must comply with provisions ofthe immigration reform and control act.

MOLECULAR AND CELLULARNEUROBIOLOGY

POSTDOCTORAL POSITIONSFour postdoctoral positions centering around geneti-

cally determined degenerative diseases of the centralnervous system in humans and animals are availableimmediately in interdisciplinary programs developed atIndiana University Medical Center in Indianapolis. Twopositions require graduate or postgraduate experience inbiochemistry and/or molecular biology and two positionsrequire graduate or postgraduate experience in neuro-morphology. Salaries competitive. Equal OpportunityEmployer. Send curriculum vitae along with the names,addresses, and telephone numbers of three references to:Dr. B. Ghetti, Associate Director, Program in Medi-cal Neurobiology, Room 142, Medical Science Build-ing, 635 Barnhill Drive, Indiana University School ofMedicine, Indianapolis, IN 46202.

POSTDOCTORALRESEARCHSCIENTIST

Merck Sharp and Dohme ResearchLaboratories at West Point, PA has animmediate opening for a postdoctoralresearch position in the Genetic andCellular Toxicology Department. Thearea of research will involve the develop-ment of in vitro models to assess mecha-nisms of toxicity of pharmaceutical drugcandidates. Applicants should have abackground in cell biology, toxicology, ormolecular biology, and should be familiarwith tissue culture methods.Excellent salary and benefit programsaccompany this position at our modernresearch facilities located 25 miles north-west of Philadelphia.Please send curriculum vitae with refer-ences, transcripts and cover letter to:

Personnel ManagerAd #C-22

Research Personnel, WP42-2Merck Sharp & DohmeResearch LaboratoriesWest Point, PA 19486

EEO/AANH/Employer

FermentationOmniGene, Inc., a Cambridge, MAbiotechnology company, seeks ahighly motivated Ph.D.-level scientistto work with its molecular biologistson the development of recombinantbacterial strains for the production ofproteins, vitamins, and amino acids.Requirements include at least 3years of experience in microbialfermentations and working knowl-edge of computer-controlled,research scale fermentors andrelated equipment. Experience withBacillus advantageous. OmniGeneoffers competitive salaries, based onexperience, and an attractivepackage of fringe benefits.OmniGene is a world leader in thedevelopment and application ofnext-generation technologies in theareas of microbial productionsystems and diagnostics, and hasestablished commercial operationsin DNA probe diagnostics.Qualified candidates shouldforward resume to: OmnlGene,Inc., Human ResourcesDepartment, 85 Bolton Street,Cambridge, MA 02140.

OmniGene is anequal opportunityemployer.

The Division of AIDSNational Institute of Allergy and Infectious Diseases

National Institutes of Health

ASSOCIATE DIRECTORClinical Research Programs

The Associate Director, Clinical Research Program willlead the Medical, Pediatric, Epidemiology, andCommunity Clinical Research Branches of the Division,and be responsible for setting the Division's agenda intreatment and epidemiology research. The idealcandidate will be a physician and have extensiveexperience in HIV medicine and clinical trials, a broadscientific perspective, proven leadership abilities, andbe BC/BE or similarly credentialed in internal medicine,pediatrics or epidemiology/public health.

For more information send C.V. to and/or call:

Dr. Jack KillenDeputy Director, Division of AIDSNational Institute of Allergy andInfectious Diseases

Control Data Building, Room 249P6003 Executive BoulevardBethesda, MD 20892(301) 496-0545

U.S. Citizenship requiredN/H is an Equal Opportunity Employer

MOLECULAR BIOLOGY

QIAGEN INC. is a fast growing *----Los Angeles area company, QIAGENcommitted to excellence in 1AGENthe development and marketing of unique andinnovative products for molecular biology. We areseeking highly motivated and talented individualsto join our expanding sales team.Eastern Regional Sales ManagerApplicants should have a BS/MS degree in mole-cular biology or related fields and 2+ years of labexperience in molecular biology. 3-5 years salesexperience is required (in molecular biology con-sumables preferred). Will be responsible for sixsales reps in the Eastern region.Technical Sales RepresentativesApplicants should have a BS/MS degree in mole-cular biology. Prior sales experience is beneficial,but not required. Sales territories are available inthe Northeast, Southwest, Midwest and Northwest.We offer competitive salaries, benefits includingrelocation assistance and a challenging, highgrowth environment. For immediate considera-lion, please send a resume, salary history andreference names to:

QIAGEN, INC., Human Resources,9259 Eton Avenue, Chatsworth, CA 91311(Phone: 800-426-8157, Fax 818-718-2056).

CARDIOVASCULAR PHARMACOLOGYSmithKline Beecham, a world leader in pharmaceuticalresearch, has an immediate Postdoctoral Scientist opportunityavailable in its Cardiovascular Pharmacology Department.

As a member of this research group, the selected can-didate, in collaboration with pharmacologists, biochemists,and molecular biologists, will explore interactions betweenendothellum and vascular smooth muscle as they relate tomuscle proliferation. The main research focus will be toestablish new cardiovascular models in vivo and in vitro.

Requirements for this position include a Ph.D. inPharmacology, Physiology, Cell Biology or Molecular Biology,and research experience with growth factors and cell cultureis desired. In addition, the successful candidate must have ademonstrated record of contribution to scientific publicationsand good oral and written communication skills. Researchexperience with surgery and a foundation of molecular biol-ogy techniques is also desired.

Our state-of-the-art research facilities are located insuburban Philadelphia, near Valley Forge, PA. We offer acompetitive compensation/benefits/relocation package and astimulating environment in which to grow and excel. Forconfidential consideration, please submit your C.V. and thenames of three references to: Nancy Hasson, EmploymentAdministrator, #H0173, SmithKline Beecham Pharmiceuti-cals, P.O. Box 1539, King of Prussia, PA 19406-0939. We arean Equal Opportunity Employer, M/F/H/V.

SBSmithKItne Beecham

Pharmaceuticals

1

t.;CAll

Public Health Service

*.Postdoctoral Scientists ||INational Institutes of HealthFellowship in Brain

Genentech Inc., a state-of-the-art leader in the biotechnology Lipid Metabolismindustry, has immediate opportunities for two PostdoctoralScientists to conduct independent research on thThetegn Institute o nAging, Nationalfamily of cell adhesion reeptors. Institutes of Health, invites

applications for a Fellowship positionYou will be joining a multidisciplinary team whose goal is to to study brain lipid metabolism indiscover specific integrin antagonists. Current studies are relation to development, aging anddirected at characterizing novel integrins. Parallel studies are neuroplasticity, pharmacological andphysiological activation in animals.directed at elucidating the molecular and cellular basis of Research opportunities includeintegrin/ligand interactions as well as understanding their examination of incorporation ofbiological functions. radiolabeled fatty acids into brain,

using analytical techniques toQualified candidates must have a PhD with experience in one of examine mass and specific activity

within precursor pools andthefollowingareas: ProteinEngineering,MolecularandCell phospholipid species; examiningBiology, or Biochemistry. Candidates with an interest in struc- brain lipid composition in Alzheimerstural biologyare particularly encouraged to apply. disease. The position is located in

Bethesda, Maryland, and is availableGenentech offers an excellent salary and benefits package immediately.coupled with the opportunity to make a significant contribution Interested candidates should submitto our organization. For immediate consideration, please send their Curriculum Vitae and two lettersyour resume to Yvonne Davino, Genentech, Inc., Dept YSSB, of recommendation to: Stanley 1.460 Point San Bruno Blvd., South San Francisco, CA 94080. We Rapoport, M.D., Chief, Labora-tory of Neurosciences, Nationalactively support and promote affirnative action and equal Institute on Aging, Nationalemployment opportunity. Institutes of Health, Bldg. 10,

Room 6C103, 9000 RockvillePike, Bethesda, MD 20892

Genen ech, Inc. ||| NI is an Equal Opportunity Employer

I~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

'~\V CIENCECLIP AND FAX CLASFIED AD ORDER FORMTV 0P) To: Science Classified Advertising

From: Phone: ( )

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Pharmaceutical

WE HAVE $9.2 BILLIONIN SALES. WOULD YOU CARETO MAKE IT $10 BILLION?

SmithKline Beecham is a $9.2 billion global pharmaceuticaland health care company. Our world famous products andreputation mean unsurpassed opportunities for individuals tocombine their scientific and marketing expertise as RegionalMedical Associates.

Our Regional Medical Associates establish relation-ships within major medical institutions for the purpose ofacting as scientific liaison and providing in-depth informa-tion regarding SmithKline Beecham products. This includesthe training of representatives and medical professionals.Travel 45%.

To qualify, you must have a Ph.D. in Pharmacology,Toxicology, Microbiology or related life sciences. Strong mar-keting and communication skills ;And a high degree of initia-tive are also required. An opportunity currently exists in theSan Francisco Bay to Sacramento Valley area.

We offer one of the best compensation packages-including car-in the industry. If you'd like to be a part ofour success, send your resume and salary history to: SCIENCE,BOX #6, Science Classified Advertising, 1333 H Street, NW,Room 940, Washington, DC 20005. We are an Equal Oppor-tunity Employer, M/F/H/V.

SBSmithKline Beecham

Pharmaceuticals

Enquiries may also be sent through BITNET to PERWPH@NUS3090, or through Telefax: (65) 7783948.

AIDS Research at theCenters for Disease Control

Atlanta, GeorgiaResearch Microbiologists

The Laboratory Investigations Branch, Division of HIV/AIDS, isseeking scientists with proven ability to conceive and conductindependent research in molecular virology, immunovirology,and recombination genetics. The Centers for Disease Controlprovides a unique opportunity to collaborate in strongly estab-lished epidemiology programs at an international level andmaintains a large historical library of HIV variants from through-out the world on which to draw for research. Qualified re-searchers will participate in studies of viral as well as hostregulatory elements involved in HIV genetic variation andaltered immunopathogenicity.

Ph.D., M.D., or equivalent years of experience in Microbiology,Immunology, or Molecular Biology with specific training intissue culture and the handling of viral pathogens preferred.Experience in the immunopathogenesis of retroviruses, in vitroexpression systems, and/or protein chemistry is desirable.Salary will depend on experience.

For additional information regarding these positions, contactDr. Mark A. Rayfield or Dr. Gerald Schochetman at (404)639-1000. Interested applicants should send their applicationsand curriculum vitae to:

William NelsonPersonnel Management Specialist

Centers for Disease Control1600 ClIfton Road

Atlanta, Georgia 30333COC is an equal opportunity employerand provides a smoke free environment.

NATIONAL UNIVERSITY OF SINGAPORE

* LEE KUAN YEW|POSTDOCTORAL FELLOWSHIP

A prestigious research fellowship known as the Lee Kuan Yew Postdoctoral Fellowship was recently established in the National University of Singapore(NUS). Applications for the Fellowship are invited from candidates with excellent academic records and research potential, and who had obtained their PhDdegrees in the last few years.

The Fellowship will be tenable for 3 years in the first instance, with possible extension for 2 further years. It will be held concurrently with the candidate'sappointment as a research staff member in the Faculty of Medicine, Faculty of Science or the Institute of Molecular and Cell Biology.

Under the Fellowship, a tax-free stipend of US$1,500 per month will be provided. This will be in addition to the following terms of appointment normallyprovided to a research staff member:

* Gross annual emoluments range from S$50,390 to S$64,200. (The commencing salary will depend on the appointee's qualifications and experience.)(US$1.00 = S$1.74 approximately)

* Leave and medical benefits will be provided. Depending on the type of contract offered, other benefits may include: provident fund benefits or an

end-of-contract gratuity, a seting-in allowance of S$1,000 or S$2,000, subsidised housing at nominal rentals ranging from S$100 to S$216 p.m.,education allowance for up to three children subject to a maximum of S$1 0,000 per annum per child, passage assistance and baggage allowancefor the transportation of personal effects to Singapore.

* The appointee may undertake consultation work of a specialist nature, subject to prior approval, and retain consultation fees up to the equivalent of60% of annual gross salary in any one year.

All academic staff have access to the following computer and telecommunication resources: an individual microcomputer (an IBM-AT compatible or AppleMacintosh), an IBM mainframe computer with 16 MIPS of computing power; an NEC SX supercomputer with 665 MFLOPS of computing power; departmentallaser printers; a wide spectrum of mainframe and microcomputer software; on-line library catalogue; voice-mail; the international computer networks-BITNETand INTERNET, linking academic institutions and research centres all over the world. The campus-wide network, which is based on the high speed opticalfibre based FDDI technology, enables the academic community to access all the computing resources in the University from the convenience of the individualworkstation.

Application forms and further information on terms and conditions of service may be obtained from:

The DirectorPersonnel DepartmentNational University of Singapore10 Kent Ridge CrescentSingapore 0511

1

Em

CANCER PREVENTIONFELLOWSHIP PROGRAM

The Division of Cancer Prevention andControl (DCPC) is acceptingapplications for the Cancer PreventionFellowship Program (CPFP). Thepurpose of this program is to attractindividuals from a multiplicity of healthscience disciplines into the field ofcancer prevention and control. Theprogram provides for: Master ofPublic Health training (new feature);Participation in the DCPC CancerPrevention and Control AcademicCourse; Working at NCI directly withindividual preceptors on cancerprevention and control projects; Fieldassignments in cancer prevention andcontrol programs at other institutions.Funding permitting, as many as tenFellows will be accepted for up tothree years of training, beginning July1, 1992 (date may vary for M.P.H.applicants). Benefits include selectedrelocation and travel expenses, paidfederal holidays, and participatoryhealth insurance.

ELIGIBILITYM.D. or D.D.S. from a U.S., territorial,or Canadian Medical School orequivalent experience. Foreignmedical graduates must have currentECFMG/FMGEMS certification andappropriate experience, e.g., one yearresidency in a training programapproved by the Accreditation Councilfor Graduate Medical Education.

OR

Ph.D., Dr. P.H. or other doctoraldegree in a related discipline(epidemiology, biostatistics, and thebiomedical, nutritional, public health orbehavioral sciences) or equivalentexperience. Foreign education mustbe comparable to that received inaccredited U.S., territorial, orCanadian institutions.

PLUS

U.S. citizenship or resident alieneligible for citizenship within fouryears.

For details and application catalogsend a postcard or letter with yourname and home address to:

Douglas L. Weed, M.D., M.P.H.,Ph.D, Director, Cancer PreventionFellowship Program, Division ofCancer Prevention and Control,National Cancer Institute,Executive Plaza South, T-41,Bethesda, MD 20892.

Further Inquiries: Mrs. BarbaraRedding (301) 496-8640 or 496-8641

Deadline For Receipt ofApplications:

SEPTEMBER 1, 1991

NIH is an Equal Opportunity Employer

CANCER

QUESTION

A SCIENCE Reprint Booklet

Due to the popularity ofScience's recent three-partseries by Robert Pool exam-

ining the debate over thepossible biological effects ofelectromagneticfields,weputthe articles together in one

convenient and comprehen-sivereprintbooklet. The first

article looks at the epidemio-logical evidence for.a link be-tween electromagnetic fieldsandcancer. Thesecondarticledeals with cell and animalstudies, and the third exam-ines policy questions and thepolitics behind the research.

To order copies of this book-let, complete the coupon be-low and send your check,payable to AAAS. All ordersmust be prepaid.

reprint price/piece Total # orderedbooklets1-20 $3.25 Subtotal

21-29 $2.50 CA shipment, add tax_

30 or more $2.00 Total

NAME

ADDRESS

CITY

STATE ZIP

MAIL TO:Corrine Harris * AAAS/Reprints1333 H Street, NW * Washington, DC 20005

POSITIONS OPEN

POSTDOCTORAL POSITION

A postdoctoral position is available to study regulationof cardiac myocyte ion currents and contractions byneurotransmitters and intracellular messengers. Candi-dates with recent Ph.D. or M.D. should have broadpreparation and exmertisein cellular electrophysiologyand signal transduction. Send curriculum vitae and threeletters of reference by 31 August 1991 to: Dr. AchillesPappano, University of Connecticut Health Center,Pharmacology L6004, rmington, CT 06032. AnAfflrmativeAction/Equal Opportunity Employer, M/W/H.

POSTDOCTORAL POSITIONIN HUMAN GENETICS

THE ROCKEFELLER UNIVERSITY

Position available immediately for a Ph.D. in molecu-lar biology to participate in ongoing work using linkageanalysis and positional cloning approaches to identify thegenetic defect in Fanconi anemia, an autosomal recessivedisease with predisposition to birth defects and malig-nancy. Send curriculum vitae and three references to: Dr.Arleen D. Auerbach, The Rockefeller University,1230 York Avenue, New York, NY 10021.An Equal Opportunity/Affirmative Action Employer.

WASHINGTON UNIVERSITYSCHOOL OF MEDICINE

POSTDOCTORAL POSITION. Available in celland molecular biology of receptor trafficking and itsregulation by post-translational modification. Experiencein immunochemical methods, transfection/expression inmammalian cells including site-directed mutagenesis isdesirable. Send curriculum vitae and two references to:Dr. Robert Fallon, Departments of Cell Biology andPediatrics, Washington University School of Medi-cine, Box 8116, St. Louis, MO 63110.

POSTDOCTORAL POSITIONAvailable for investigations ofcellular/molecular mech-

anisms of neurodegenerative diseases. Our laboratoryuses a variety of approaches to study several humanneurodegenerative diseases, including Alzheimer's dis-ease and motor neuron disease, and related animal mod-els. This position is part of a research program dealingwith several research areas, including the neuronal cy-toskeleton, transmitter systems, the amyloid precursorprotein, and trophic factors.Send curriculum vitae and two letters of recommenda-

tion to: Donald L. Price, M.D., Neuropathology Lab-oratory, The Johns Hopkins University School ofMedicine, 509 Pathology Building, 600 North WolfeStreet, Baltimore, MD 21205-2181. Affirmative Ac-tion/Equal Opportunity Employer. We encourage applica-tions from minorities. Because of funding requirements,applicants limited to U.S. citizens/permanent residents.

CENTRE FOR POPULATION BIOLOGYTHREE POSTDOCTORAL RESEARCHERS

INSECT ECOLOGISTMATHEMATICAL POPULATION BIOLOGISTEXPERIMENTAL POPULATION BIOLOGIST

Required at Imperial College's NERC-sponsored In-terdisciplinary Research Centre, based at Silwood Park,Ascot:An INSECT ECOLOGIST with interests in theoret-

ical and experimental metapopulation dynamics, andpopulation genetics, to work principally on the insectfaunaof ragwort (in collaboration with the GeneticsGroup at University College London).A MATHEMATICAL POPULATION BIOLO-

GIST to study the implications ofmass mortality for thedynamics and genetics of metapopulations (in collabora-tion with the NERC Sea Mammal Research Unit, Cam-bridge).An EXPERIMENTAL POPULATION BIOLO-

GIST with an interest in developing and testing popu-lation models in simple laboratory sytems. ndidatesinterested in linking models with field populations alsoconsidered.

All posts are to March 1994 in the first instance. Salaryrange: £11,399 to £18,165 (under review).

Further details and applications: Professor J. H.Lawton, FRS, Centre for Population Biology, Impe-rial College at Silwood Park, Ascot, Berks SL5 7PY,England. Telephone: 0344-294346. Closing date: 2August 1991.

SCIENCE, VOL. 253m

POSITIONS OPEN

POSTDOCTORAL POSITION. Available in neu-roendocrinology. Applications are invited from personswith a Ph.D. and/or M.D. for research with a neuroen-docrine group investigating the roles played by neu-ropeptides in central disorders and in small-cell carcino-ma. Position restricted to U.S. citizen or resident. Sendcurriculum vitae and three letters of reference to: Dr.William G. North, Department of Physiology, Dart-mouth Medical School, Hanover, NH 03756. Dart-mouth College is an Equal Opportunity Employer.

POSTDOCTORAL POSITION. Research involvesinsect behavioral response to toxins and its geneticcorrelation with physiological susceptibility. Expertise inquantitative genetics is required; expertise in mathemat-ical modeling and behavioral studies is desirable. Appli-cations for this 2-year position will be accepted immedi-ately and until the position is filled. Submit curriculumvitae and names and addresses of three references to: Dr.Casey W. Hoy, Department of Entomology, OhioAricultural Research and Development Center,Wooster, OH 44691.

CORNELL UNIVERSITYCOLLEGE OF VETERINARY MEDICINE

DEPARTMENT OF PATHOLOGY

A POSTDOCTORAL POSITION IN MOLECU-LAR BIOLOGY is available immediately to participatein a study of gene interaction during lung development.Emphasis will be placed on studying the interactionbetween protooncogenes and differentiation-specificgenes. Candidates will have a Ph.D. in molecular biologyand experience in DNA sequencing techniques. To ap-ply, please send curriculum vitae and three letters ofrecommendation to: Dr. Roy Levine, Department ofPathology, College of Veterinary Medicme, CorneliUniversity, Ithaca, NY 14853-6401. Cornell Univer-sity is an Equal Opportunity/Afirmative Action Employer/Educator.

POSTDOCTORAL POSITIONS

Two postdoctoral positions available immediately tostudy mechanisms of retinoid receptor-mediated regula-tion of epithelial growth and differentiation or autocrinefactors involved in epithelial transformation. Theseprojects will employ techniques of normal and trans-formed human keratinocyte cell culture, hybridizationanalysis ofRNA expression, protein purification, cDNAcloning, and gene transfer using defective retroviruses.Applicants should have a Ph.D. emphasizing molecularor genetic approaches to the study of problems in cell ordevelopmental biology and employment eligibility veri-fication. Send curriculum vitae, summary of researchexperience, thesis abstract, reprints, and the names ofthree references to: Dr. James G. Rheinwald, Depart-ment of Research and Development, BioSurfaceTechnology, Inc., 64 Sidney Street, Cambridge, MA02139. An Equal Opportunity Employer.

POSTDOCTORAL FELLOW

A postdoctoral fellowship is available in the RadiationEffects Branch of the Naval Research Laboratory. Theposition is in a new basic research program to studyionizing radiation interactions in macromolecules, in-duding DNA. Applications are invited from candidateswith a Ph.D. in biology, biochemistry, biophysics, orradiation biology. The successful candidate will be famil-iar with gel electrophoresis, other separation techniques,and preparation of DNA samples. The appointment,administered through the National Research Council, isfor 2 years with an option for a third year. The stipend isa minimum of $36,000 per year. Position is availableimmediately. For fulther information, contact: Dr.Michael A. Xaesos, Code 4615, Naval Research Lab-oratory, Washington, DC 20375-5000. Telephone:202-767-3938.

An Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL FELLOWSHIP POSITIONIN CARDIAC CELLULAR ELECTROPHYSIOL-OGY. Available immediately in Mayo Foundation. M.D.or Ph.D. degree required. Experience of the patch clamptechnique is preferred. For further information, pleasecontact: Yoshihisa Kurachi, M.D., Ph.D., Division ofCardiovascular Diseases, Mayo Clinic, Rochester,MN 55905. Telephone: 507-284-1834. FAX: 507-284-9111. Mayo Foundation is an Affirmative Action andEqual Opportunity Educator and Employer.

Senior ScientistsCellular and Molecular

BiologyThe Ontario Cancer Institute/PrincessMargaret Hospital is one of North America'slargest cancer research and treatmentcentres, and houses the Department ofMedical Biophysics of the University ofToronto. The institute invites applications forsenior scientist positions in its Division ofCellular and Molecular Biology. Currentprograms in this group include: cellular andmolecular aspects of haemopoiesis,immunology, differentiation, oncogenesis,leukemia/lymphoma and gene regulation.New members should be eligible foracademic appointments in the Department ofMedical Biophysics of the University ofToronto, a graduate department thatemphasizes strong multidisciplinary research.Preference will be given to individuals withresearch interests in fields such as:molecular biology, oncogenes, regulation ofcell cycle, developmental biology and signaltransduction.In accordance with Canadian Immigrationrequirements, first consideration will be givento Canadian citizens and permanentresidents. In accordance with theEmployment Equity Policy of the University ofToronto and the Ontario CancerInstitute/Princess Margaret Hospital,applications are invited from all qualifiedwomen and men.

Interested persons should send theircurriculum vitae, statement of researchinterests, and names of three references, to:Tak W. Mak, Ontario Cancer Institute/Princess Margaret Hospital, 500 SherbourneStreet, Toronto, Ontario M4X 1 K9.

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* HOSPITA L -

5 JULY 1991

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RESEARCH ASSOCIATE Ir: Il MOLECULARAND l|OdlrtlCELLULARBIOLOGY 1 AgouronAmgen is a leader in the applicationsrof Pi c S, kilmolecular and cellular biology to the RECEPTR STRUCTURE BASEDdevelopment of human therapeutics. DRUG DESIGNOur successes in the development ofEpogen® (recombinant human erythro- gouron Phac tic nc., a recognized pioneer and.poe.l lrec iadthmneryho afin the field of rtional drug design, is located in lapoietin) and Neupogen@ (recombinant Jolla, California in the midst adynamic and challengingevonnof wademicandiedustiaresearchcenters. Wehuman granulocyte colony stimulating are seeking talented Ph.D. scientists to join ourfactor) have placed us firmly at the fore- |multidisciplinary team in the following areas:front of the biotechnology industry. As a A background in macromolecular crystallography and ex-result of these successes and our con- refinement andPlentarhcis required.elson,tinuing commitment to research, we are Computational Chemistrytinuing commitment to researc, wearefTraining and experience in quantum mechanics,actively seeking a Research Associate maolecularsimuiationsquantiativemolecularmodel-

_ _ ing force field development, ~~~~~orother computer assistedfor our Inflammatory Cell Research drequired. Scientific programmingProgram. The success candidate for each position must be willing

to interact closely with colleagues in a wide range of scien-The objectives of this program are to tific disciplines.We offer competitive salaries and benefits in a superb loca-isolate and characterize protein factors tion. asendurrsmesandthenamesofreferences.. . ~~~~~~~~~~~~~~~~inconfidence to:and corresponding genes involved in Human Resources Reference - BVmigration and activation of phagocytes. 11025 North Torrey Pines Road, La Jolla, CA 92037Minimum qualifications include a BS orMS in an appropriate field with two yearsof laboratory experience in molecularand cellular biology. Experience in basicrecombinant DNA methodologiesand/or cell culture techniques is highly Public Health Servicedesirable. National Institutes of Health

Amgen offers a stimulating and chal- National Cancer institute, Division of Cancer Treat-lenging environment on the leading ment, Clinical Oncology Program, Radiationedge of biotechnology as well as an Oncology Branchattractive location among the Santa Position Title: Radiation Oncoiogist, PhotodynamicMonica coastal mountains. Our com- TSPoR ialistpensation and relocation packages TeaySeilsreflect Amgen's commitment to attract Job Description: The position will entail clinicaland retain the best scientific talent pos- trials with photodynamic treatment in conjunction with thesible. .i

y heb the necssary psk Surgery Branch, NCL. In addition laboratory efforts, bothIsible. If you have the necessary skiIISlls | chemical and biologic, toward a wider use and under-and would like to be a part of a company standing of photodynamic sensitizers is a key componentthat places its highest priority on its of this position.human resources, please send a Qualifications: M.D. who is B.E. or B.C. inresume or CV, in confidence, to: Radiation Oncology with experience in both academic

AMGEN, INC.Recruitment, Dept. #595Amgen CenterThousand OaksCA 91320-1789Equ_

Op0rnityEmffY~ At,

radiation oncology and specifically photodynamic therapy.The applicant should have a broad background in thebasic sciences.

Salary: Dependent upon qualifications.Location: Building 10, NIH, Bethesda, MD. Ifinterested please send cover letter to: Eli Glatsteln,M.D., Chief, Radiation Oncology Branch, NationalCancer Institute, B-10, B3B69, 9000 Rockvllle Pike,Bethesda, Maryland 20892.

NIH is an Equal Opportunity Employer

ROMASSOCIATE DIRECTOR

CURATORIALThe Royal Ontario Museum is seeking applications for theposition of Associate Director, Curatorial (ADC), which becamevacant on the appointment of the former ADC as Director ofthe Museum. The ADC is responsible for the management,administration and financial control of the curatorial andresearch activities and related services at the Museum.Reporting to the ADC are nineteen curatorial departmentsresponsible for Earth Sciences, Life Sciences and various Artand Archaeology subject areas, as well as the Library andArchives and a Collections Management department (coveringRegistration, Conservation and Photography). The ADC isresponsible for approximately 180 staff and a total budget ofover $9 million.

The primary responsibility of the position is to provideleadership for curatorial excellence within the Museum whichwill ensure the preservation, conservation and integrity ofpresentation to the public of the Museum's collections; thequality of collections related research; and structured curatorialinput into the programme of gallery development, temporaryexhibitions, and other public programmes.

The successful candidate will hold a Ph.D. degree or theequivalent and will have demonstrated high scholarlyachievement in one of the academic subject areas covered bythe Museum. He or she will also have demonstrated superiormanagerial, communication and problem-solving skills obtainedthrough progressively more responsible positions.

The ADC reports to the Director and normally is ActingDirector in the absence of the Director. The position requiresconsiderable independent judgment and action within theADC's area of responsibility, as well as cose liaison andparticipation with other senior staff and department heads inorder to ensure the success of the Museum's many objectives.The ADC has frequent contact with Museum trustees,members and volunteers, as well as various governmentagencies.

The position is a term appointment for five years made by theBoard of Trustees on the recommendation of the Director, andrenewable by mutual consent. A qualified candidate could begranted a curatorial position in the Museum at the end of theterm of office as ADC.

The salary for this position will be comparable to similar levelsof responsibility in Ontario Universities and other publicinstitutions and the appointment will be effective at as early adate as can be mutually agreed.

Applications should be sent to Dr. John McNeill, Director,Royal Ontario Museum, 100 Queen's Park, Toronto,Ontario, Canada, MI5S 2C6, no later than August 31, 1991.

In accordance with Canadian Immigration regulations, thisadvertisement is directed primarily to Canadian citizens andpermanent residents of Canada; others who are interested inthe poskion are invited to write indicating their interest.

We want people

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Imagination can get you everywhereat Anheuser-Busch. We could not havegrown to become America's #1 brewer,and one of the Fortune 50, without akeeneye for innovation- not only in our prod-ucts, but also in social and environmen-tal concerns.

Food MicrobiologistResponsibilities for this position

include initiating and executing pro-

grams to assist in the quality asgr-

ance development of aseptic bever-ages and new food, products. Theseprograms willWecompass spoilage or-

ganism identification,HACCPprograadevelopmentand the evaluation thelatest rapid nmbhods.

The idealitsdWate must hatchatleast a Master's der in microbiologyor food nicrwj )ii

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You believe thatittikeepthe onlyway to keepsunotenjoyalltherewards andadvthat such leadership can bring? LookintoAnheuser-Busch.Andfindyourplaceat the top. Send your resume today to:ANHEUSER-BUSCH COMPANIES; Cor-porate Employment; Dept A61KB-134;One Busch Place; St. Louis, MO 63118.

We are an Equal OpportunityEmployer.

ANHELWSER-BLSiCHCOMPANIESWe're behind some ofthe best ideas in the businessI

POSITIONS OPEN

POMS OCTORAL FELLOW. In Frederick, Mary-land. Forty hours per week, 8:30 a.m. to 5:00 p.m.;salary: $30,472 per year. To conduct research in molec-ular biology ofETS ges to develop nmthodologies forthe large-scale production of recombinant proteins forstrucural studies. This entails te construction ofvariousexpression vectors, identification of relevant proteins,development of protocols to p 10- to 100-milligramquantities of such proteins. Experience in developmentof oxidation techques deling with the conversion ofalkanolamines and B-hydroxymtrosamines to the corre-sponding ketones, research on the physicalchemicalproperties of carcin-modified DN Knowledgeand skill in organic chemistry, biology of ETS proteins,gas chromatography, liquid column chromatography, gelfiltration chromatography, high-pressure liquid chroma-tography, ultraviolet spectroscopy, nudear magnetic res-onance, and mass spectroscopy. Ph.D. or equivalentqualification in biological science and 1 yearoflaboratoryexperience in purification of ETS recombinant proteinsfrom micrograms to milligam requied Mail resumeand copy of ad to: D.E.E.D., 1100 North EutawStreet, Room 212, Baltimore, MD 21201. J.O.#9048004.

COMPUTATIONAL CHEMISTRY/QSARPOSTDOCTORAL ASSOCIATE POSITION

The University of Minnesota seeks a postdoctoralassociate to develop quantitative structure-activity rela-tionships (QSAR) of drugs, industrial chemicals, andtoxic asents.Minimum qualifications: A PhD. degree in medicinal

chemistry or chemicalbiological sciences with substantialcourse work in strcturl chemistry and computer sci-ence. Ph.D. degree must be completed by starting date ofappointment.

Desired qualifications: (i) familiarity with modemtechniques ofQSAR evident from peer-reviewed publi-cations, (ii) two or more years ofexperience in universityor industrial setting working in computational chemistryor QSAR, and (iii) experience in obtaining external grantsupport. The latest state-of-the-art hardware and soft-ware are available.

Salary is negotiable. To apply, send an applicationletter, current rsume, and the names, addresses, andtelephone number of three references. Applications mustbe postmarke by 1 August 1991. Send applications to:QSAR Search Commi Natural Resources Re-search Institute, University ofMinnesota, 5013 Mill-er Trunk Highway, Duluth, MN 55811.The University ofMinnesota is committed to thepolicy that

all persons shall have equal acces to its programs, facilities,and employment without regard to race, religion, color, sex,national origin, handicap, age, veteran status, or sexualorentation.

POSITDOCTORAL RESEARCH ASSOCIATE.In Soil Ecology and Nutrient Cycling. To work onlrge-scale, multidisciplinary study of nitrogen cyclingand biological process in high and low chemical inputagricultural systems, in relation to groundwater contam-ination with nitrates. Research will involve biologicalN-transformations, uptake, and export. Duties are fieldsampling, laboratory analyses, and data analysis.

Qualifications: Ph.D. in relevant subject. Experience innutrient cycling and analyses with knowledge of soilecology. Two-year appointment from 30 July 1991 withpotential renewal. Salary competitive. Send letter, tran-scripts, and three references to: Dr. J. M. Blair, Ento-mology Department, Ohio State Unity, 1735Neil Avenue, Cohimbus, OH 43210, telephone: 614-292-0372, by 24 July 1991.

U.S. DEPARTMENT OF AGRICULTUREAGRICULTURAL RESEARCH SERVICE (ARS)POSIDOCTORAL RESEARCH ASSOCIATE,

NURIITION AND IMMUNE STATUS. Two-yearappointment. Western Human Nutrition Research Cen-ter (WHNRC), San Francisco, California, seeks candi-date with a recent Ph.D. in immunology/nutrition/bio-chemistry/related fields to study regulation of immunestatus by dietary fats and other nutrients in humans.Experience in immunological assays, tissue culture, andeicosanoids desirable. Salary: $33,605 to $40,278 plusbenefits. Call 415-5564381 or send rdsumr to: Dr. D.S. Kelley, WHNRC, Box 29997, Presidio of SanFrancisco, CA 94129. ARS is an Equal OpportunityEmployer.

104

POSITIONS OPEN

Immediate opening. POSIDOCTORAL FEL-LOW/RESEARCH ASSOCIATE. A position for amolecular biologistwith experience in developing recom-binant and chumeric antibodies is now open. Responsi-bilities will include production and testing of novelfusion proteins and elopment of immunotoxins forcancer therapy. Salary commensurate with experience.Contact: Dr. M. Rosenblum, Ph.D., Chief; Immuno-pharmacology Section, Department of Clinical Im-munology and Biological Tpy, M. D. AndersonCancer Center, 1515 Holcombe Boulevard, Box 041,Houston, TX 77030. Equal Opportunity Employer.

ANTICIPATED POSTDOCTORAL RE-SEARCHER OR RESEARCH ASSOCIATE. Posi-tion available for 1 to 3 years. Postdoctoral researcher:Ph.D. required. Research associate: M.S. required. Expe-rience in benthiC/estuarine ecology. Responsibilities: con-duct inde t research and particapate m ongoingprojects on bioturbation, fishing feeding, and responses topollutants. Anticipated hire date is 1 September 1991,pending final apval. Send lett of application curric-ulum vitae, andf three letters of reference to: Dr. John W.Fleeger, Dpartmet of Zoology and Physiology, Lou-na Sta University (LSU), Baton Rouge, LA

70803-1725. Teephone: 504-388-1132; FAX: 504-388-1763. Application deadline is 15 August 1991. LSUis an Equal Opportunity Employer.

The Fred Hutchinson Cancer Research Center is seek-ing an M.D. or Ph.D. for an appointment at the AS-SISTANT MEMBER level in human immunogenetics.This individual must have a strong background in humanimmunogenetics and be capable of providing leadershipin the development and implementation of state-of-the-art molecular methods for analysis of HLA genes. Ap-plicants must have the ability to conduct independentresearch. Candidates should send curriculum vitae, aconcise statement of their research plans, three letters ofreference, and letter of application to: Clinical ResearchDivision New Appointments Committee, HumanImmunogenetics Search, M246, Fred HutchinsonCancer Research Center, 1124 Columbia, Seattle,WA 98104. Smoke-free environment. An Equal Opportu-nity Employer.

SENIOR RESEARCH BIOCHEMIST. Elucida-tion of structure of drug metabolites. Determination ofmolecular weight and structures ofproteins and polypep-tides. Develop and implement analytical methods todetermine drug candidates and their metabolites in bodyfluids. Liquid chromatography in combination with at-mospheric pressure ionization mass spectrometry. Deter-mination of minute amounts of drugs and their metab-olites with human and animal body fluids. Proteinmapping and sequencing applying mass spectrometryand capillary electrophoresis. Preclinical biotransforma-tion studies. Requires Ph.D. in analytical chemistry and 2years of postdoctoral experience in atmospheric pressureionization MS/MS as applied to qualitative and quanti-tative analysis of zenobiotics and in metabolites in bodyfluids. Use of supercritical fluid chromatography in con-junction with double focusing mass spectrometry andapplication of capillary electrophoresis-atmosphericpressure ionization mass spectrometry for characteriza-tion of peptides. Forty hours per week; $54,000 per year.Send r~sume or curriculum vitae to: Philadelphia JobBank, 444 North 3rd Str, Philadelphia, PA 19123,JO #4382511, with proofoflegal authority to work in theUnited States.

RESEARCH SCIENTIST. Forty hours per week;salary: $45,000 per year. Conduct research into biofilmformation, techniques for monitoring the formation ofbiological deposits in paper mills, and factors affectingthe growth of filamentous organisms. Modeling indus-trial systems and the use oftechniques, including electronmicroscopy, to monitor the development of biofilms andthe efficacy of chemical removal and/or prevention ofbiofouling. Supervise customer service laboratory per-sonnel. Requirements: Ph.D. in biological sciences; musthave 1 year of experience in job offered or 1 year ofexperience as research associate. Must have expertise inbacterial biofilms in industrial environments, filamentousgrowth of bacteria, modeling of industrial systems, bio-cide efficacy studies, and electron microscopy as evi-denced by published materials and invited presentations.Send rvsumd to: Job Service of Florida, 1307 NorthMonroe Street, Tallahassee, FL 32303. Job Order #FL-0455002. Must show legal proof of right to workpermanently in the United States.

POSITIONS OPEN

ASSOCIATE STAFF SCIENTIST. By 5 August1991, please send resume to: Employment SecurityDepartment, Employment Service Division, Job #253372-D, Olympia, WA 98504. Job description:Conducts independent research in purification of murineand human hematopoietic stem cells using dual lasermultiparameter flow cytometry, and the identification,purification and molecular cloning of cytokines affectingdifferentiation and self renewal ofpuripotent stem cells asassessed by in vitro and in vivo assays. Requirements:Must have Ph.D. in experimental hematology. Must have2 years of scientific research experience in purificationand analysis of hematopoietic stem cells, including utili-zation of dual laser multiparameter flow cytometry, anddevelopment of screening assays for cytokines. Must havepublished three articles in related subjects in refereedscientific journals. Must have proofoflegal authority to workin the United States. Salary range: $38,000 to $42,000per year, depending on experience. Forty hours per week,9:00 a.m. to 5:00 p.m., Monday through Friday. Positionis in Seattle, Washington. Equal Opportunity Employer.SENIOR RESEARCH ASSOCIATE. A position

for a molecular biologist is immediately available toinvestigate the molecular mechanism involved in cell tocell communication and intracellular Ca2' regulation ofthe myometrium during pregnancy and labor. Interestedpersons having a Ph.D. in biochemistry or molecularbiology and at last 3 years of postdoctoral researchexperience in cloning and gene expression in mammaliansystem are encouraged to apply. Preference will be givento candidates having expertise in cDNA cloning; se-quencing; Northern, Western, and Southern blotting;polymerase chain reaction; fusion protein vectors con-struction; and designing of primers and cDNA probes.Previous expertise in studies of the gap junctions and N'and Ca2W pumps in relation to myometrial activity isrequired. Send curriculum vitae to: Robert E. Garfield,Ph.D., The University of Texas Medical Branch(UTMB), Department of Obstetrics and Gynecology,301 University Boulevard, E-87, Galveston, TX77550. UTMB is an Equal Opportunity/MIF/VIHIAffir-mative Action Employer. UTMB hires only individualsauthorized to work in the United States.

SENIOR AND INTERMEDIATE LEVELSTAFF ENVIRONMENTAL SCIENTISTS

Vermont-based consulting firm involved in interna-tional development work, seeks senior and intermediatelevel environmental scientists for home-office technicalsupport of projects in watershed management, environ-mental impact assessments, agriculture, forestry, andother resource management. Minimum MS/M.A.,Ph.D. preferred, in environmental or natural resourcesfields with 5 to 10 years of professional experience.Overseas development experience an asset. Primary skillsin EIA, resources inventories, and field research. Knowl-edge of French or Spanish helpful. Some short-termoverseas travel required. Willingness and ability to devel-op domestic work desirable. Applicants should send cur-riculum vitae to: Associates m Rural Develpment(ARD), Inc., Department El, P.O. Box 1397, Burling-ton, VT 05402. ARD is an Equal Opportunity Employer.RESEARCH MICROBIOLOGIST. Forty hours

per week, 9:00 a.m. to 5:00 p.m.; salary: $28,000 peryear. Conduct culture screening and optimixation exper-iments with anaerobic bactena to produce hydrogenfrom synthesis gas. Develop cultures of methanotrophicbacteria to convert methane into methanol. Define opti-mal cultures of anaerobic bacteria to produce acetic acidfrom waste gases. Bacterial physiology experiments tomaximize the performance of various microorganisms.Preparation of research reports and proposals. Minimumrequirements: Ph.D. with major or specialty in microbi-ology, 2 years ofexperience in anaerobic bacteria, includ-ing bacterial physiology, manipulation of conditions tomaximize culture performance, operation of fermenta-tion systems, culture screening and isolation, authorshipof two articles on bacterial physiology and anaerobicfermentation that have been published in microbiologyjournals. Send risume to: The Employment SecurityDivision, P.O. Box 1205, Fayetteville, AR 72702, JobOrder #538699. Must have proof of legal authority to

work in the United States.

SCIENCE welcomes placement of line classified adsby FAX. Please include name and telephone number forour confirmation call when transmitting ad to:

FAX NUMBER: 202-682-0816

SCIENCE, VOL. 253

1

Keystone Symposia1992 Meetings

Intermediate Biomarkers of Precancer and theirApplication in ChemopreventionOctober 3-7, 1991; Keystone, Colorado

Inflammation, Growth Regulatory Molecules andAtherosclerosisJanuary 13-19, 1992; Keystone, Colorado

Molecular Biology of the Endothelial CellJanuary 13-19, 1992; Keystone, Colorado

Transcription Regulation in Development,Differentiation and DiseaseJanuary 13-20, 1992; Tamarron, Colorado

Molecular and Cellular Biology of Host-ParasiteInteractionsJanuary 15-20, 1992; Park City, Utah

Bone Marrow TransplantationJanuary 19-26, 1992; Keystone, Colorado

Molecular Mechanisms in DNA Replication &RecombinationJanuary 25 - February 1, 1992; Taos, New Mexico

Negative Growth ControlJanuary 26 - February 2, 1992; Keystone, Colorado

Positive Growth ControlJanuary 26 - February 2, 1992; Keystone, Colorado

Nutrition & Central Nervous System FunctionFebruary 2-6, 1992; Lake Tahoe. California

Cytokines in Growth. Development and PathogenesisFebruary 1-8, 1992; Taos, New Mexico

Melanoma and Biology of the Neural CrestFebruary 1-8, 1992; Taos, New Mexico

Steroid/Thyroid Receptor Gene Super FamilyFebruary 21-27, 1992; Tamarron, Colorado

HematopoiesisFebruary 27 - March 5. 1992; Tamarron, Colorado

Cell Biology of Virus Entry. Replication andPathogenesisFebruary 28. March 5, 1992; Taos, New Mexico

Recognition of Endotoxin in Biologic SystemsMarch 1-7, 1992; Lake Tahoe, California

Antigen Presentation Functions of the MHCMarch 5-11, 1992; Taos, New Mexico

Breast and Prostate CancerMarch 7-13,1992; Lake Tahoe, California

Strategies in Chemoprevention of Hormone-Dependent CancersMarch 10-13,1992; Lake Tahoe, California

Metal Ion/Molecular Biology InterfaceMarch 13-19, 1992; Lake Tahoe, California

GlycobiologyMarch 21-27, 1992; Park City, Utah

Prevention and Treatment of AIDSMarch 27 - April 3, 1992; Keystone, Colorado

Critical Research Directions in Pediatric HIV InfectionMarch 27-31, 1992; Frisco, Colorado

Fundamental Mechanisms of TranscriptionMarch 28 - April 3, 1992; Copper Mountain, Colorado

Advances in Understanding NeurodegenerativeDisordersMarch 28 - April 4, 1992; Big Sky, Montana

Synapse Formation and Function: The Neuromus-cular Junction and the Central Nervous SystemMarch 28 - April 4, 1992; Big Sky, Montana

Molecular Biology of Human Genetic DiseaseApril 3-10, 1992; Copper Mountain, Colorado

Gene Transfer, Replacement and AugmentationApril 3-9, 1992; Copper Mountain, Colorado

Growth and Differentiation Factors in VertebrateDevelopmentApril 3-10, 1992; Keystone, Colorado

Tissue EngineeringApril 3-10, 1992; Keystone, Colorado

Integrins: Cell Adhesion and TransmembraneCommunication in Development and DiseaseApril 3-10, 1992; Keystone, Colorado

Crop Improvement via Biotechnology:An International PerspectiveApril 10-16, 1992; Keystone, Colorado

JRegistration in any meeting in a shaded groupqualifies for attendance in any meeting in thatgroup.

For more information please contact:

Keystone SymposiaDrawer 1630, Dept. S.Silverthorne, CO. 80498Phone: (303) 262-1230 . Fax: (303) 262-1525

We'll Help You BuildA New Lab

Let the free Science product in-formation service put you in touchwith the vendors whose productsyou will need.

Simply write us a letter statingthe specifics about your proposedlab and the instruments andsupplies you need. We will do therest. Write to:

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SCIENCE

GENOME SEQUENCINGCONFERENCE mISeptember 22-25, 1991

Hyatt Regency, Hilton Head, South CarolinaAbstract deadline August 2. 1991

The third annual Genome Sequencing Conference is an international conferencedevoted to discussion of the most current analyses and approaches tounderstanding the human genome. Innovative research by U.S., European andJapanese groups will be presented and discussed. Presentations will detaildiscoveries from the human genome and model organisms including mouse,Drosophila, C. elegans, yeast, plants, E. coli, M. capricolum and a number ofviruses. State-of-the-art technologies and new computational approaches will alsobe covered. Poster sessions, workshops and discussion groups will provide aforum for researchers to present their latest data. Early registration isencouraged.

Co-chairs: J. Craig Venter (NIH) and Leroy Hood (CalTech)

Participants to include: M. Adams, F. Blattner, D. Botstein, J. Bowie, C. Cantor,C. T. Caskey, E. Chen, A. Efstratiadis, C. Fields, R. Gesteland, R. Gibbs,

W. Gilat, H. Goodman, D. Hard, M. Hunkapiller, R. Keller, B. Koop, M. Lalande,D. Lipman, A. Martin-Gallardo, W. R. McCombie, R. Moyzis, W. Nierman,D. R. Sibson, T. Smith, J. Sulston, E. Uberbacher, J. Watson, D. Yandell

For further Information contact:Susan Wallace, Genome Sequencing Conference Ill,

P. 0. Box 541, Rockville, Maryland 20848, (301) 480-0634(301) 480-8588 FAX, E-mail: swallaceiloglady.ninds.nih.gov

K

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6

POSITIONS OPEN

STAFF SCIENTISTPerform the following functions in relation to freeze-

dried red cells: Develop biophysical and biochemicaltechniques to evaluate the membrane viscoelasticity andgeometry with the use of rheological techniques includ-ing laser diffractometry, filtrometry, viscometry, and celltransit analyzer. Test the aggregation behavior with theuse of light transmission method. Test the effects ofdrugs on the rheological properties. Monitor the efficien-cy of the lyophilization process to preserve the integrityand physiological function. Statistical analysis ofdata andpreparation of papers for publication in scientific jour-nals. Requirements: Ph.D. in pharmacology (rheology).Special knowledge in and/or ability to use: Theory andexperimental techniques in blood rheology, characteriza-tion ofred cell membrane properties, methods for assessingoxidative stress in red cells, rheokgical techniques indudinglaser diffractory, filtromety, viscmey, cell transit ana-lyzer, and light tansmision method. Salary: $55,000 peryear. Jobntenrview site: Pasaea, California. Send this adand rdsume to: Job #TC11211; P.O. Box 9570, Sacra-mento, CA 95823-0570 no later than 19 July 1991.

SENIOR RESEARCH ASSOCIATESECTION LEADER, PERMANENT POSITIONACADEMIC APPOINTMENT POSSIBLE

E rienced biochemist with glycoconjugate interestin ce biolo at UHSIThe Chicago Medical School,Heather M. B ih Cancer Biology Research Laboratory.Bench-work-orented individual with meticulous work-ing habits for in-depth investigations of role of humancarcinoma cell membrane glycoconjugates in primarytumor establishment. Technical help available. Especiallyoutstanding salary and benefits in view ofthe importanceof the academic task, not grant-dependent. Send curric-ulum vitae, details of bench-work expertise, and bibliog-raphy to: Box 538, Lake Bluff, IL 60044. EqualOpportunity Employer, M/F.

RESEARCH ASSISTANT. Full time, to developand manage monoclonal antibody production facility.Experience in animal tissue culture, production of hy-bridomas, and antibody selection techniques mandatory.Ability to develop ELISA assays required. Managementskills are critical. Interest in developing collaborativeinteraction with faculty important. Send letter ofinterest,curriculum vitae, transcript of all academic records, andthree letters of reference to: Dr. Russel Meints, Centerfor Gene Research and Biotechnology, 3096 CordleyHail, Oregon State University (OSU), Corvallis, OR97331-2906. Application deadline is 31 July 1991.OSU is anAfflrmativeAction/Equal Opportunity Employerand complies with Section 504 of the Rehabilitation Act of1973. OSU has a policy ofbeing responsive to the needs ofdual-career couples.

SENIOR RESEARCH ASSOCIATE. For firm innortheastern Ohio. To perform research on numericalsimulations of materials processing, with the aim ofprocessing key materials for the semiconductor industryand developing high-temperature materials and coatingsfor aerospace engineering. To apply finite element meth-ods and boundary element methods to the solution ofproblems in fluid dynamics, transport phenomenon incrystal growth, and polymer processing. Involves exten-sive use of Cray 2, Cray X-MP, and Cray Y-MP supercomputers. Must have Ph.D. in engineering mechanicsor materials science and academic program must haveincluded one graduate course each in the areas of:advanced finite element analysis, molecular theory ofpolymer materials, introduction to polymer rheology,applied numerical methods, and advanced mechanics ofcontinua. Must have had 6 months of experience asresearch assistant or materials scientist and research expe-rience must have been in computational fluid dynamics.Must be conversant with advanced finite element meth-ods and boundary element methods as well as with thespecial software package FIDAP (Fluid Dynamics Anal-ysis Package) and ability to perform advanced scientificcomputations on Cray super computers including theCray 2, X-MP, and Y-MP with a good knowledge of thevectorization and parallel processing techniques, as evi-denced by academic letter(s) of reference, employertestimonial(s), and/or publication(s). Forty hours perweek, 8:30 a.m. to 5:30 p.m., Monday to Friday;$41,000 per year. Must have proofoflegal authority to workpermanently in the United States. Send resum6 and coursetascript in duplicate (no calls) to: J. Davies, JO#1255727, Ohio Bureau of Employment Services,P.O. Box 1618, Columbus, OH 43216.

POSITIONS OPEN

SENIOR WETLAND ECOLOGIST. Salaried po-sition with existing wetland regulatory team in theHouston office of a national consulting firm. Advanceddegree required in wetland ecology or related discipline.Duties include wetland delineations, environmental as-sessments, mitigation design, and implementation. Posi-tion offers growth in other areas of environmental con-sulting, project management, and client development.Submit resumes to: James 0. Jones, Espey, Hustonand Associates, Inc., P.O. Box 519, Austin, TX78767.

RESEARCH ASSOCIATE. For university in north-eastern Ohio. To conduct laser light scattering andmagnetic field deformation experiments on monomer

and polymer liquid crystal materials to understand theliquid crystal phases and phase transitions, investigatesurface topography of vacuum deposited thin films to

determine the aligning mechanism of liquid crystal mol-ecules using atomic force and scanning tunneling micro-scopes, write manuscripts for publication m scientificjournals, and present the work at scientific meetings.Must have a Ph.D. in physics. Ph.D. dissertation must bein the area ofliquid crystal physics with special emphasison liquid crystal phases and phase transitions. No expe-

rience required. Forty hours per week, 8 a.m. to 5 p.m.;

$24,000 per year. Musthave proofoflegal authority to work

permanently in the United States. Send resume in duplicate(no calls) to: G. Maugans, JO# 1295334, Ohio Bu-reau of Emplo nt Services, P.O. Box 1618, Co-lumbus, OH426

ASSOCIATE RESEARCH BIOLOGIST

The Department of Biological Sciences, The Univer-sity of Alabama, seeks applicants for a nontenure-track,3-year, research position with possibility of renewal forthree additional years. Responsibilities include develop-ing and managing databases and networking activities forbiological collections, long-range planning for and acqui-sition of hardware and software, and network connec-

tiviq for biological specimen data resources. Strongpreference for a Ph.D. in biological systematic relatedfields and experience with biological accession data andfor demonstrated success in securing extramural funding.Experience with dBASE is essential and familiarity withUNIX systems and TCP/IP-based network communica-tions is desirable. Send letter of interest, resume, andthree letters of reference to: Dr. Robert R. Haynes,Department of Biological Sciences, The University ofAlabama, Box 870344, Tuscaloosa, AL 35487-0344.The University ofAlabama is an Equal Opportunity/Aflir-mative Action Employer.

COURSES AND TRAINING

HYPERTENSION SUMMER SCHOOL

15 to 20 September 1991, Heinsheim Castle, Germa-ny. Co-sponsored by The International Union of Phar-macology (IUPHAR); The World Hypertension League(WHL); The TRANSGENEUR Program of the Euro-pean Community; The College de France/INSERM,Paris; The German Institute for High Blood PressureResearch, Heidelberg.

This is a 1-week residential course in English for recentM.D. and Ph.D. graduates beginning a career in clinicaland experimental high blood pressure research. Topicswill include: molecular and cellular biology of cardiovas-cular disease; vascular endothelium; and general aspectsof hypertension research. Maximum class size will be 20students.

Faculty: F. Alhenc-Gelas, Paris; P. Corvol, Paris; D.

Ganten, Heidelberg; M. Lathtop, Paris; J. Menard,Paris; J. Mulfins, Edinburgh- M. Paul, Heidelberg; J.Pouyssegur, Nice; R. Rettig, Heidelberg; F. Soubrier,Paris; T. Unger, Heidelberg.To apply, please send within the next 2 weeks curric-

ulum vitae with publication list, two letters of reference,and a note indicating your scientific and personal inter-ests and expectations from the course to: HypertensionSummer School, German Institute for High Blood

Pressure Research, Wielandtstrage 26, D-6900Heidelberg, Germany. Telephone: +49-622145099.FAX: +49-6221-402485. Course fee, including mate-

rials and accommodation, is 250.00 German marks. A

number of educational grants are available and studentsin need are encouraged to apply informally. The summer

school is supported by an educational grant from The

Parke-Davis Conference Series.

POSITIONS OPEN

The Fred Hutchinson Cancer Research Center is seek-ing an M.D. or Ph.D. for an appointment at the AS-SISTANT MEMBER level in neurobiology. This indi-vidual must have a strong background in basicneurological sciences addressing problems of cellulardifferentiation and gene regulation. In addition to devel-oping an independent research program, the candidatewill articipate in clinical activities and the developmentof cinically oriented neurological studies. Candidatesshould send curriculum vitae, a concise statement of theirresearch plans, three letters of reference, and letter ofapplication to: Clinical Research Division New Ap-pointments Committee, Neurobiology Search, M246,Fred Hutchinson Cancer Research Center, 1124 Co-lumbia, Seattle, WA 98104. Smoke-free environment. AnEqual Opportunity Employer.

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Reader serice number 46

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Large Marine Ecosystems

Patterns, Processes, and WeldsKenneth Sherman, Lewis Alexander,and Barry Gold, editors

1990; 247 pp.; Softcover;ISBN #0-87168-384-9(indexed and illustrated)#90-30S; $34.95 (AAASmembers $27.95)

Large marine ecosystems (LMEs)- the relatively narrow ocean zones thatproduce nearly 95% of the world's useable marine biomass - are becomingincreasinglystressedbybothnatural andanthropogenic changes, arousingmajorinternational concern about potentially negative ecologic and economic ef-fects.This volume, from a AAAS symposium, deals with the projected impacts of

global changes on ocean productivity, and provides scientific, geographic,socioeconomic, and legal arguments formanagingLMEs asmultinationalunits,in order to sustain biomass yields of major coastal regions.A useful book for conservationists and natural resource policymakers.

I. Perturbations and Yields of LargeMarine Ecosystems

The Weddell Sea: A High Polar Ecosystem G. HempelEnvironmental Influence on Recruitment and Biomass Yieldsin the Norwegian Sea Ecosystem -B. Ellertsen, P. Fossum, P.Solemdal, S. Sundby, and S. TilsethFluctuation in the Cod Biomass of the West Greenland SeaEcosystem in Relation to Climate- H. Hovgaard and E. BuchThe Caribbean Sea: A Large Marine Ecosystem in Crisis W.J. Richards and J. A. BohnsackProductivity and Fisheries Potential ofthe Banda Sea Ecosys-tem J. J. Zijlstra and M. A. Baars

I1. Biodynamics of Large MarineEcosystems

Biodynamics of the Sea: Preliminary Observations on HighDimensionality and the Effect of Physics on Predator-PreyInterrelationships B. J. Rothschild and T. R. OsbornPhysical-Optical-Biological Scales Relevant to Recruitment inLarge Marine Ecosystems T. D. DickeyDirect Simulation of the Effect of Turbulence on PlanktonicContact Rates - T. Osborn, H. Yamazaki, and K SquiresApplication of Molecular Techniques to the Study of MarineRecruitment Problems -D. A. Powers, F. W. Allendorf, and T.ChenApplication of Image Analysis in Demographic Studies ofMarine Zooplankton in Large Marine Ecosystems - M. S.Berman

Growth, Survival, and Recruitment in Large Marine Ecosys-tems - G. C. LaurencePerspectives on Larval Fish Ecology and Recruitment Pro-cesses: Probing the Scales of Relationships - C. T. Taggartand K. T. Frank

Ill. Theory and Management of LargeMarine Ecosystems

Scaling Pattern and Process in Marine Ecosystems - R. E.RicklefsPhysical and Biological Scales and the Modelling of Predator-Prey Interactions in Large Marine Ecosystems - S. A. LevinBiomass Potential of Large Marine Ecosystems: A SystemsApproach - N. J. Bax and T. LaevastuProductivity, Perturbations, and Options forBiomass Yields inLarge Marine Ecosystems - K. ShermanGeographic Perspectives in the Management ofLarge MarineEcosystems - L. M. AlexanderInterrelationships ofLaw in the Management ofLarge MarineEcosystems - M. H. Belsky

Other books in the series:Variability and Management ofLarge MarineEcosystemsKenneth Sherman and Lewis M. Alexander, editors, 1986Biomass Yields and Geography ofLarge MarineEcosystemsKenneth Sherman and Lewis M. Alexander, editors, 1989Available from Westview Press, Boulder, Colorado.

Order from: By mail, individuals must prepay with check or charge card. Send check to AAAS Books, Dept. A27, PO Box753, Waldorf, MD 20604.- By phone (use VISA/MasterCard only) call 301-645-5643 (9am-4pm ET) and ask for AAAS. By fax,301-843-0159. Add $4.00 postage/handling per order. Please specify item #89-18S. For shipments to California, add applicablesales tax.

American Association for the Advancement of Science

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