yhr

Substrate channeling , intermediates Never leaves the enzyme surface

In TCA cycle main chemical reactions are :-

1. Oxidation reduction 2. Hydration dehydration 3. Substrate level

phosphorylation4. Decarboxylation

1. All dehydrogenase group 2. Aconitase and fumarase3. Succinyl CoA synthase .

4. Specially isocitrate and 2-oxoglutarate dehydrogenase.

Anaplerotic Reactions Replenishes TCA cycle intermediate.

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