tablet press double rse version 9.12

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RIGHT STUFF EQUIPMENT GZPT Series Triple Discharge GZP Series Single Discharge GZPS Series Double Discharge GZPY Series Removable Turret

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Page 1: Tablet Press Double RSE Version 9.12

RIGHT STUFF EQUIPMENT

GZPT Series

Triple Discharge

GZP SeriesSingle Discharge

GZPS SeriesDouble Discharge

GZPY SeriesRemovable Turret

Page 2: Tablet Press Double RSE Version 9.12

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GZPS Series Double Discharge High Speed Tablet Press Machine

Page 3: Tablet Press Double RSE Version 9.12

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Introduction

GZPS series are automatic double discharge high speed rotary tablet press machines

Models include 79, 73, 61 and 49 station machines

Double force feeding and double discharge. Two powder filling, dosing, pre-pressing, main pressing and ejection stations with each revolution

Page 4: Tablet Press Double RSE Version 9.12

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Technical Parameters

Model GZPS-79 GZPS-73 GZPS-61 GZPS-49

No. of Punches 79 73 61 49

Revolving Speed (min-max)

16~72 16~72 16~72 16~72

Max. Output ( 000/h ) 14~68 14~63 11.7~52.6 9.4~42.3

Max. Dia. ( mm ) 11 13 16 25

Die Dia. (mm) 22 24 30.18 38.1

Motor Power KW 11 11 11 11

Main pressure KN 100 100 100 100

Pre-pressure KN 100 100 100 100

Max. Filling Depth 16 16 16 20

Dia. of Punch mm 19 19 19 25.35

Pitch Circle Diameter mm 680 680 680 680

Weight Kg 4,800

Dimension mm1,300 X 1,300 X 2,000

Dimension of electrical cabinet

930 X 730 X 1,450

Page 5: Tablet Press Double RSE Version 9.12

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Environment and Material Conditions

• Work Environment– Compliant with cGMP

• Powder requirements– 12 - 60 mesh, good compressibility and flow properties– Homogeneous powder– Non Hygroscopic– Good Compression

• Tablet Type– Round, oval, custom shapes, – Double sided lettering – Double layers tablet– Annular tablet

Page 6: Tablet Press Double RSE Version 9.12

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Frame Construction

Four column structural support. The

four standing columns, together with the

foundation board and top board, form a

rigid body. The generated force during

operation is balanced resulting in low

vibration and robust operation.

Page 7: Tablet Press Double RSE Version 9.12

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Component Construction

Vibration canceling hydraulic system.

Compress rollers are supported by high strength mechanical structure which prevents oil leaking and tablet contamination

Stable Pressure

Page 8: Tablet Press Double RSE Version 9.12

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Pre-pressure

Effectively expels the air in the die

Forms primary tablet shape in dies

Max. pre- pressure 100KN

Heavy pre-pressure guarantees good air

exhausting before tablet shaping. This reduces

the “uncap” rate and improves the production

speed by up to 50%.

Page 9: Tablet Press Double RSE Version 9.12

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Main Pressure Presses tablet to final thickness

Controls the penetration depth of upper

punch

Controls the tablet hardness with

pressure

Controls tablet thickness

Max. main pressure 100 KN

Page 10: Tablet Press Double RSE Version 9.12

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Pressure and Roller Diameter

Same diameter for pre-press and main press rollers achieves maximum pre-pressure and main pressure up to 100KN.

Page 11: Tablet Press Double RSE Version 9.12

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Pressure Detection Advantages

1 Principle of detection: Punch force exerted on rollers and the roller force is measured by the sensor. No need for conversion of the signal. The value displays on the screen directly

2 German Tedea-Huntleigh gravity sensor;

3 The sensor is installed directly below the roller center with capacity to 10T .

Detect directly. Because it is located under the roller center detection errors can be avoided. The result is increased accuracy in filling dosage and even tablet weight

Easy changing and calibration can be completed in the field

Not effected by time and temperature

Easy to test and verify.

Multi-detection for each punch guarantees precise pressure when compared with traditional strain gauge type pressure transducer

Page 12: Tablet Press Double RSE Version 9.12

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Pressure and Roller Diameter

Page 13: Tablet Press Double RSE Version 9.12

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Pressure Sensor

German TEDEA gravity sensor LCD50 KTT, pressure detection accurate and direct.

Paster strain gauge type sensor, low accuracy

Dr Pharm Some other machines

Page 14: Tablet Press Double RSE Version 9.12

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Pressure Amplifier Comparison

Dr PharmDr Pharm Swiss Pressure Swiss Pressure

AmplifierAmplifier

Other typesOther types Amplifier Amplifier circuit circuit

boardboard

Page 15: Tablet Press Double RSE Version 9.12

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A 2000 string encoding count plate is A 2000 string encoding count plate is installed on the turret. After 4 frequency installed on the turret. After 4 frequency software conversion, the count plate becomes software conversion, the count plate becomes 8000 string. Each punch gets 8000/49=163 8000 string. Each punch gets 8000/49=163 pulses. For each pulse we collect a press pulses. For each pulse we collect a press value. By comparing the pressing values, we value. By comparing the pressing values, we arrive at the maximum press value. arrive at the maximum press value.

Punch orientation is easy to set up at an Punch orientation is easy to set up at an operator level and does not require operator level and does not require maintenance staff for set up.. By setting up maintenance staff for set up.. By setting up the parameters on the screen, the orientation the parameters on the screen, the orientation can be completed.can be completed.

Punch Orientation Method

Page 16: Tablet Press Double RSE Version 9.12

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Pressure DetectionDr Pharm punch orientation encoder

Other machine type punch orientation sensor

Page 17: Tablet Press Double RSE Version 9.12

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Pressure and Dosing Display

Page 18: Tablet Press Double RSE Version 9.12

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Operating Method No hand adjustment wheels. Main machine is separated from electrical cabinet,

which keeps potential dust away from controls. Pressure and filling position are controlled by servo

motor synchronized with the encoder and displayed on the HMI touch screen

High accuracy with precision to 0.01mm

Page 19: Tablet Press Double RSE Version 9.12

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Controlled Operating Parameters Pressure and thickness adjustment

Tablet weight and dosing adjustment

Automatic lubrication system

Primary motor and feeding motor

Page 20: Tablet Press Double RSE Version 9.12

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Electrical Control System Austrian B&R Industrial Automation Company’s

Programmable Computer Controller . Industrial design, conform to 21 CFR Part 11.

Master frequency: 600MHz, 15 times of PLC speed , C language programming, scan cycle 400us , program memory space 64M , 300 collection points of punch value.

PCC interface232 serial port485 serial portSupports Profibus protocol & TCP/IP Ethernet protocol

Page 21: Tablet Press Double RSE Version 9.12

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Electronic Systems Employed

Internationally branded key components guarantee the reliability and stability of electrical control system.

I/O Controller-BandR Touch screen (main machine controller)-BandR Frequency converter –U.S. LENZE Gravity sensor –German

TEDEA Servo motor -KINCO Electric amplifier –Switzerland FLINTEC Rotary encoder- Japan Low-voltage apparatus-Schneider, Muller Color touch screen menu:

Machine operation status online display, automatic alarm with malfunction, automatic stop, trouble shooting display.

Production information can be displayed, printed and stored.

Page 22: Tablet Press Double RSE Version 9.12

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Upper and lower punches too tight

Electrical control system

Main motor overload

Feed motor overloading

Emergency stop

Pressure over load detection

Monitor the pressure in pre-pressure stage. Stops punches

immediately

Electronic Auto Protection

Page 23: Tablet Press Double RSE Version 9.12

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Electrical Control System

Tablet Weight Control

– Average tablet weight precision ±2%

– Tablet weight < 0.3g: Tablet weight discrepancy ±5%

– Tablet weight ≥0.3g: Tablet weight discrepancy ±3%

Page 24: Tablet Press Double RSE Version 9.12

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Sanitation and Maintenance Double cover board between drive area and tablet

press area means a leak proof structure. Drive area remains clean for extended period.

Page 25: Tablet Press Double RSE Version 9.12

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Sanitation and Maintenance

Fans in the tablet press area and drive area maintain positive pressure reducing any powder build up.

Modular structure. Upper rollers, lower rollers and dosing parts are easily removed. Each piece fixed by four screws. All the guide rails can be easily changed for machine maintenance.

Change over time of all the guide rails and rollers is less than 1 hour.

Rubber ring sealing for dies keeps them clean

Page 26: Tablet Press Double RSE Version 9.12

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Force Feeding

Double layer 3 paddle wheel central powder feeding deviceTop stir wheel increase the powder fluidity and consistencyBottom stir wheels for powder filling and dosing provides precise filling depth controlFeeding motor controlled by frequency converter with overload protection and variable speed control.

Double layer 3 paddle wheel feeding device

Page 27: Tablet Press Double RSE Version 9.12

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Dust Collection Device

Dust collection system is aluminum alloy. Thumb screws mean it is easily dismantled and cleaned completely.

Page 28: Tablet Press Double RSE Version 9.12

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Working Area 304 Stainless surface, smooth

and clean. No corrosion

Hermetically sealed tablet pressing area, totally separated from drive area

Interlocked glass door

Two dust collection ports in the tablet press area

Easy to clean the tablet press area. Cover plate can be easily dismantled

Conform to GMP and FDA requirements

Page 29: Tablet Press Double RSE Version 9.12

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Lubrication SystemDouble lubrication system. Grease for bearings and oil for punches and

guide rails.

Batch type and low flow auto pressure oil lubrication system.

Precision distributing valve and central lubrication pump. Oil amount

controlled by electrical system with interval controls avoids tablet

contamination caused by oiling splashing.

Sealed central grease lubrication system is clean, convenient and reliable.

Upper punch caps reduce oiling.

U.S. Bijur oil and grease lubrication system with alarm provides reliable

and fail safe lubrication.

Page 30: Tablet Press Double RSE Version 9.12

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Lubrication System

Page 31: Tablet Press Double RSE Version 9.12

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Machine Guide Rails

Precision guide rails control the movement path of upper and lower punches.

All the filling rails use cosine curve and added lubrication points, which extends the useful life. Also reducing the punch abrading and noise.

All the cams, guide rails are processed by CNC, trilinear coordinate measuring instrument, which guarantee the precision of helicoid and even curve arcs resulting in guaranteed stable punch movement.

Page 32: Tablet Press Double RSE Version 9.12

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Machine Guide Rails

Machines are equipped with different guide rail sets for thick and light tablets pressing. Guide rails change over is easily done in less than an hour.

Equipped with guide rails auto recognition device. The guide rails are recognized automatically after installation. Position of dosing guide rails and press rollers are automatically adjusted to a safe position if the wrong guides are installed.

Page 33: Tablet Press Double RSE Version 9.12

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Punch and Dies

EU standard Die : Cr12MoV alloy tool

steel. Good hardness and wear properties.

Punches : 6CrW2Si alloy tool steel. Good hardness and wear properties.

100% interchangeability GZPS-49 D type GZPS-61 B type GZPS-73 BB type

Page 34: Tablet Press Double RSE Version 9.12

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Other Functions

Permanent magnetic force damping for lower punches. Lower punches have no contact with damping melt, which extends punch life and guarantee the consistency of damps, avoiding punch bounce and unrestrained drop down with reduced operating noise.

Oil and dust control for the dies and punches.

Page 35: Tablet Press Double RSE Version 9.12

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Conforms to GMP

Stainless construction and smooth surfaces within tablet press area. Electronics and drive components are separate from tablet press area. Dustproof and oil proof sealing protection for punch holes effectively

keeps powder from penetrating drive parts. Dust cover on the touch screen maintains a clear display. 360 access for cleaning. All materials conform to GMP

Page 36: Tablet Press Double RSE Version 9.12

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CNC Production Area

Foundation Bed Production

Page 37: Tablet Press Double RSE Version 9.12

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CNC Production AreaHigh precision CNC ensures precision of spare parts and exact part

replacement. CNC machines: CPV-1200B, 3060VMC, CPV-900, 1020VMC/A, Haas Vertical & more

Page 38: Tablet Press Double RSE Version 9.12

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CNC Production Area

High precision CNC ensures precision of spare parts and exact part replacement. CNC machines: CPV-1200B, 3060VMC, CPV-900,

1020VMC/A, Haas Vertical & more

Page 39: Tablet Press Double RSE Version 9.12

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Processing EquipmentHigh precision CNC ensures precision of spare parts and exact part

replacement. CNC machines: CPV-1200B, 3060VMC, CPV-900, 1020VMC/A, Haas Vertical & more

Page 40: Tablet Press Double RSE Version 9.12

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CNC Production Area

HBM-5T Horizontal boring and milling machining center

Page 41: Tablet Press Double RSE Version 9.12

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Processing Equipment for Tooling

Page 42: Tablet Press Double RSE Version 9.12

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Detection EquipmentTrilinear coordinates measuring instrument, imported from

Switzerland, precise inspection for complex spare parts.

Page 43: Tablet Press Double RSE Version 9.12

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Tablet Machine Production Area

Page 44: Tablet Press Double RSE Version 9.12

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Supplemental Equipment

Uphill tablet de-duster• Tablet elevating and tablet

de-dusting, mainly used for connecting to tablet press machine and metal detector.

• Long de-dusting path, automatic tablet turnover and polishing. Effective de-dusting conforms to GMP.

Page 45: Tablet Press Double RSE Version 9.12

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Supplemental Equipment

• This machine is mainly composed of blower, filter, fan, pulse ash removing, controls and ash collection.

• Reversible air blasts extends filter life.

• Filter cartridge submicron filtering. Clean space.

• Convenient operation and maintenance.

• Colleting on the spot, disposing on the spot

• Outer cover stainless material.

AS-59Ⅲ Dust collector

Page 46: Tablet Press Double RSE Version 9.12

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Corollary Equipment

Technical parameters

TypeAS-59Ⅲ

Air volume ( m3/h ) 1400~1600

Available pressure ( Pa ) 950-590

Filter area ( m2 ) 12

collection efficiency 99.99

Power 380V/50Hz

Nominal power 2.2kW

Dimension ( L×W×H )(mm)

560×580×1530

Weight (kg) 135

AS-59Ⅲ Dust collector

Page 47: Tablet Press Double RSE Version 9.12

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Parts Lists and AvailabilitySer. NO. Computer NO. Name Chart NO. Material Amount Remarks

01 2600000281 Seal ring FB32x44x10 JBY-399 1

02 2101135 nomolock 1-35 nodular cast ironQT450-10

1

03 9000700800 angular contact ball bearing 7008AC

GB/292-93 2

04 21011322 gasket 1-322 Q235A 2

05 2101000026 compressed spring 5x32x75.6

GB2089-80 1 p=10.1 ;n=6; n0=8

06 2101138 Helical gear end cap 1-38 45 1

07 Round nut M20X1.5 GB812-88 2

08 2101136 Helical gear 1-36 45 1

09 9000700100 angular contact ball bearing 7001AC

GB/292-93 1

10 2101137 Worm 1-37 30CrMo 1

11 9000720300 angular contact ball bearing 7203AC

GB/292-93 1

Page 48: Tablet Press Double RSE Version 9.12

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Technical DocumentsSer. Ser. NO.NO. NameName AmountAmount RemarksRemarks

1 Product specification 1

2 Product quality certificate 1

3 Purchased parts specification and certification 1

4Quality certificates for materials contacting with powder

1 set

5 GMP authentication documentation

5.1 Equipment maintenance regulations 1set

5.2 Equipment cleaning and disinfecting regulations 1set

5.3 Equipment test and verity project 1set

5.4 Equipment cleaning and disinfecting checking project 1set

5.5 Equipment maintenance and overhauling regulations 1 set